JPS55143982A - Thiophene derivative - Google Patents
Thiophene derivativeInfo
- Publication number
- JPS55143982A JPS55143982A JP15913479A JP15913479A JPS55143982A JP S55143982 A JPS55143982 A JP S55143982A JP 15913479 A JP15913479 A JP 15913479A JP 15913479 A JP15913479 A JP 15913479A JP S55143982 A JPS55143982 A JP S55143982A
- Authority
- JP
- Japan
- Prior art keywords
- derivative
- formula
- thienyl
- reacting
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Abstract
NEW MATERIAL:A thiophene derivative of formula I (R is lower alkyl or phenyl).
EXAMPLE: 1-Methylsulfinyl-1-methylthio-2-(2'-thienyl)ethylene.
USE: Industrially useful intermediate of thienyl acetic acid or its derivative which is a chemical modifier for antibiotics such as penicillin and cephalosporin.
PROCESS: The compound I is prepared by reacting an aldehyde of formula II with formaldehyde mercaptal S-oxide of formula III in the presence of a strong base (e.g. alkyl lithium) which exhibits ≥pH10 as 0.1N aqueous solution. The compound I can be converted to thienyl acetic acid or its derivative in high yield, by reacting with water or an alcohol in the presence of a mineral acid.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15913479A JPS5829952B2 (en) | 1979-12-10 | 1979-12-10 | Thiophene derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15913479A JPS5829952B2 (en) | 1979-12-10 | 1979-12-10 | Thiophene derivative |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1235476A Division JPS5295657A (en) | 1976-02-09 | 1976-02-09 | Furan or thiophen derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS55143982A true JPS55143982A (en) | 1980-11-10 |
JPS5829952B2 JPS5829952B2 (en) | 1983-06-25 |
Family
ID=15686984
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP15913479A Expired JPS5829952B2 (en) | 1979-12-10 | 1979-12-10 | Thiophene derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5829952B2 (en) |
-
1979
- 1979-12-10 JP JP15913479A patent/JPS5829952B2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
JPS5829952B2 (en) | 1983-06-25 |
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