HU172304B - Process for producing 7-thiazolylacetamido-ceph-3-eme-4-carboxylic acid derivatives - Google Patents

Process for producing 7-thiazolylacetamido-ceph-3-eme-4-carboxylic acid derivatives

Info

Publication number
HU172304B
HU172304B HU75TA00001381A HUTA001381A HU172304B HU 172304 B HU172304 B HU 172304B HU 75TA00001381 A HU75TA00001381 A HU 75TA00001381A HU TA001381 A HUTA001381 A HU TA001381A HU 172304 B HU172304 B HU 172304B
Authority
HU
Hungary
Prior art keywords
thiazolylacetamido
ceph
eme
producing
carboxylic acid
Prior art date
Application number
HU75TA00001381A
Other languages
Hungarian (hu)
Inventor
Michihiko Ochiai
Osami Aki
Akira Morimoto
Taiichi Okada
Kenji Kawakita
Yoshihiro Matsushita
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of HU172304B publication Critical patent/HU172304B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/40—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HU75TA00001381A 1975-06-09 1975-12-17 Process for producing 7-thiazolylacetamido-ceph-3-eme-4-carboxylic acid derivatives HU172304B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB24611/75A GB1536281A (en) 1975-06-09 1975-06-09 Cephem compounds

Publications (1)

Publication Number Publication Date
HU172304B true HU172304B (en) 1978-07-28

Family

ID=10214399

Family Applications (1)

Application Number Title Priority Date Filing Date
HU75TA00001381A HU172304B (en) 1975-06-09 1975-12-17 Process for producing 7-thiazolylacetamido-ceph-3-eme-4-carboxylic acid derivatives

Country Status (7)

Country Link
JP (5) JPS5822039B2 (en)
AT (2) AT344894B (en)
GB (1) GB1536281A (en)
HK (1) HK2282A (en)
HU (1) HU172304B (en)
MY (1) MY8200219A (en)
SE (1) SE444809B (en)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1536281A (en) * 1975-06-09 1978-12-20 Takeda Chemical Industries Ltd Cephem compounds
DK154939C (en) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd METHOD OF ANALOGUE FOR THE PREPARATION OF THIAZOLYLACETAMIDO-CEPHEM COMPOUNDS OR PHARMACEUTICAL ACCEPTABLE SALTS OR ESTERS THEREOF
FR2346014A1 (en) * 1976-01-23 1977-10-28 Roussel Uclaf Amino-thiazolyl-hydroxyimino-acetamido-cephalosporanic acids - with antibacterial activity
SE440655B (en) * 1976-01-23 1985-08-12 Roussel Uclaf SET TO MAKE NEW OXIME DERIVATIVES OF 7-AMINO-THIAZOLYL-ACETAMIDO-CEPHALOSPORANIC ACID
GB1576625A (en) * 1976-04-12 1980-10-08 Fujisawa Pharmaceutical Co Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof
FI771866A (en) * 1976-06-28 1977-12-29 Fujisawa Pharmaceutical Co
PH17188A (en) * 1977-03-14 1984-06-14 Fujisawa Pharmaceutical Co New cephem and cepham compounds and their pharmaceutical compositions and method of use
AU520269B2 (en) * 1977-03-14 1982-01-21 Fujisawa Pharmaceutical Co., Ltd. Cephem and cepham compounds
JPS5444695A (en) * 1977-09-13 1979-04-09 Fujisawa Pharmaceut Co Ltd 3,7-disubstituted-3-cephem-4-carboxylic acid and its salt and their preparation
US4370326A (en) * 1977-09-13 1983-01-25 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds and composition
FR2410655A1 (en) * 1977-12-05 1979-06-29 Roussel Uclaf NEW OXIMES DERIVED FROM 3-SUBSTITUTE 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC, THEIR METHOD OF PREPARATION AND THEIR APPLICATION AS MEDICINAL PRODUCTS
DE2758001A1 (en) * 1977-12-24 1979-07-12 Hoechst Ag CEPHALOSPORINE DERIVATIVES AND METHOD FOR THEIR PRODUCTION
FR2387235A1 (en) * 1978-01-23 1978-11-10 Fujisawa Pharmaceutical Co PROCESS FOR THE PREPARATION OF COMPOUNDS OF 3,7-DISUBSTITUE-3-CEPHEM-4-CARBOXYLIC ACID AND NEW PRODUCTS THUS OBTAINED, HAVING A STRONG ANTIBACTERIAL ACTIVITY
JPS54106495A (en) * 1978-02-09 1979-08-21 Dai Ichi Seiyaku Co Ltd Cephem derivative
JPS54128594A (en) * 1978-03-27 1979-10-05 Fujisawa Pharmaceut Co Ltd 3,7-disubstituted-3-cephem-4-carboxylic acid derivative
FR2432521A1 (en) * 1978-03-31 1980-02-29 Roussel Uclaf NOVEL O-SUBSTITUTED OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR USE AS MEDICAMENTS
DE2818263A1 (en) * 1978-04-26 1979-11-08 Bayer Ag BETA LACTAMANTIBIOTICS
US4703046A (en) * 1978-09-08 1987-10-27 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds and processes for preparation thereof
BE878637A (en) * 1978-09-11 1980-03-06 Fujisawa Pharmaceutical Co PROCESS FOR THE PREPARATION OF 3,7-DISUBSTITUTED 3-CEPHEM-4-CARBOXYLIC ACID COMPOUNDS AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, NOVEL PRODUCTS THUS OBTAINED AND THEIR USE FOR THEIR ANTIMICROBIAL ACTIVITIES
JPS5594354A (en) * 1979-01-12 1980-07-17 Fujisawa Pharmaceut Co Ltd Syn-isomer of 2-substituted imino-3-oxo-4-halobutyric acid, its salt, and their preparation
JPS5543089A (en) * 1978-09-12 1980-03-26 Fujisawa Pharmaceut Co Ltd Preparation of 3-cephem compound
US4409215A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical Co., Ltd. 7-Acylamino-3-substituted cephalosporanic acid derivatives and processes for the preparation thereof
JPS56125392A (en) * 1980-03-06 1981-10-01 Fujisawa Pharmaceut Co Ltd Cepham and cephem compound and preparation thereof
JPS57154175A (en) * 1981-03-16 1982-09-22 Mitsui Toatsu Chem Inc 2-thiazoleamine derivative, its preparation, and drug composition comprising it
US4457929A (en) * 1982-03-29 1984-07-03 Bristol-Myers Company 3-Quaternary ammonium methyl)-substituted cephalosporin derivatives
ATE30724T1 (en) 1982-06-28 1987-11-15 Bristol Myers Co CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
IL69246A (en) * 1982-08-07 1986-07-31 Tanabe Seiyaku Co 7-((2-aminothiazolyl-2-pyrrolidonyl or(piperidonyl)-oxyimino)acetamido)cephem carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
JPS6150973A (en) * 1983-11-16 1986-03-13 Fujisawa Pharmaceut Co Ltd Substituted iminoacetic acid derivative and salt and preparation thereof
IT1180207B (en) * 1984-07-30 1987-09-23 Istituto Biochimico Italiano PROCEDURE FOR THE PREPARATION, WITH HIGH YIELD AND PURITY, OF BETA-LACTAMIC ANTIBIOTICS
JPS60155167A (en) * 1984-07-31 1985-08-15 Fujisawa Pharmaceut Co Ltd Substituted iminoacetic acid derivative and its salt
JPS61121746U (en) * 1985-01-16 1986-07-31
EP0210815A3 (en) * 1985-07-25 1988-04-20 Beecham Group Plc 6-beta-(alpha-etherified oxyimino)-acylamino penicillanic-acid derivatives, their preparation and use
GB8519606D0 (en) * 1985-08-05 1985-09-11 Fujisawa Pharmaceutical Co 3 7-d substituted-3-cephem compounds
WO1988005776A1 (en) * 1987-02-02 1988-08-11 Teijin Limited Cephalosporin compounds or their salts, process for their preparation, and parmaceutical compositions
EP0347459A4 (en) * 1987-02-03 1990-04-10 Teijin Ltd Cephalosporin compounds or their salts, process for their preparation, and pharmaceutical compositions.
JPH02281051A (en) * 1989-04-21 1990-11-16 Toyo Tire & Rubber Co Ltd Tread rubber composition for tire
JPH09110877A (en) 1995-10-17 1997-04-28 Katayama Seiyakushiyo:Kk Cephem compound, its production and antibacterial agent containing the compound

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1536281A (en) * 1975-06-09 1978-12-20 Takeda Chemical Industries Ltd Cephem compounds

Also Published As

Publication number Publication date
JPS51149296A (en) 1976-12-22
SE444809B (en) 1986-05-12
ATA967775A (en) 1977-12-15
GB1536281A (en) 1978-12-20
JPS5756485A (en) 1982-04-05
JPS5822039B2 (en) 1983-05-06
AT347587B (en) 1979-01-10
MY8200219A (en) 1982-12-31
SE7713233L (en) 1977-11-23
JPS5989686A (en) 1984-05-23
JPS61143388A (en) 1986-07-01
JPH0346474B2 (en) 1991-07-16
ATA517177A (en) 1978-05-15
AT344894B (en) 1978-08-10
JPS58185553A (en) 1983-10-29
HK2282A (en) 1982-01-22
JPS6155905B2 (en) 1986-11-29
JPS5858353B2 (en) 1983-12-24

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628