JPS56128787A - Cephalosporin derivative and its preparation - Google Patents

Cephalosporin derivative and its preparation

Info

Publication number
JPS56128787A
JPS56128787A JP3024680A JP3024680A JPS56128787A JP S56128787 A JPS56128787 A JP S56128787A JP 3024680 A JP3024680 A JP 3024680A JP 3024680 A JP3024680 A JP 3024680A JP S56128787 A JPS56128787 A JP S56128787A
Authority
JP
Japan
Prior art keywords
formula
compound shown
cephalosporin derivative
preparation
heterocyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP3024680A
Other languages
Japanese (ja)
Other versions
JPH0129798B2 (en
Inventor
Takashi Tsuruoka
Katsuyoshi Iwamatsu
Shigeharu Inoue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meiji Seika Kaisha Ltd
Original Assignee
Meiji Seika Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Seika Kaisha Ltd filed Critical Meiji Seika Kaisha Ltd
Priority to JP3024680A priority Critical patent/JPS56128787A/en
Publication of JPS56128787A publication Critical patent/JPS56128787A/en
Publication of JPH0129798B2 publication Critical patent/JPH0129798B2/ja
Granted legal-status Critical Current

Links

Abstract

NEW MATERIAL:A cephalosporin derivative shown by the formula I [R1 is H, NH2, NHCOR4(R4 is NH2 or 1W5C alkyl optionally substituted by NH2); R2 is H, COOR5(R5 is H or 1W5C alkyl); R3 is heterocyclic, heterocyclic thio, or azide, m and n are or 2], and its pharmaceutically acceptable salt or ester.
EXAMPLE: 7-(3D,L-3-Amino-3-carboxy)propylthioacetamide-3-(1-methyl-1H-tetrazole-5-yl)thiomethyl-3-cephem-4-carboxylic acid.
USE: An antimicrobial agent. Effective against wide range of bacteria, especially having high activities in an organism.
PROCESS: For example, a compound shown by the formula II (X is halogen) is reacted with a compound shown by the formula III, to give a compound shown by the formula I. The reaction is carried out preferably in a solvent, e.g., water, etc. in the presence of an acid binder.
COPYRIGHT: (C)1981,JPO&Japio
JP3024680A 1980-03-12 1980-03-12 Cephalosporin derivative and its preparation Granted JPS56128787A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP3024680A JPS56128787A (en) 1980-03-12 1980-03-12 Cephalosporin derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3024680A JPS56128787A (en) 1980-03-12 1980-03-12 Cephalosporin derivative and its preparation

Publications (2)

Publication Number Publication Date
JPS56128787A true JPS56128787A (en) 1981-10-08
JPH0129798B2 JPH0129798B2 (en) 1989-06-14

Family

ID=12298345

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3024680A Granted JPS56128787A (en) 1980-03-12 1980-03-12 Cephalosporin derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS56128787A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0727426A2 (en) * 1995-02-15 1996-08-21 Bristol-Myers Squibb Company Cephalosporin derivatives

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6210513A (en) * 1985-07-09 1987-01-19 Matsushita Electric Ind Co Ltd Cooking unit

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6210513A (en) * 1985-07-09 1987-01-19 Matsushita Electric Ind Co Ltd Cooking unit

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0727426A2 (en) * 1995-02-15 1996-08-21 Bristol-Myers Squibb Company Cephalosporin derivatives
EP0727426A3 (en) * 1995-02-15 1996-10-23 Bristol Myers Squibb Co Cephalosporin derivatives

Also Published As

Publication number Publication date
JPH0129798B2 (en) 1989-06-14

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