JPS56128787A - Cephalosporin derivative and its preparation - Google Patents
Cephalosporin derivative and its preparationInfo
- Publication number
- JPS56128787A JPS56128787A JP3024680A JP3024680A JPS56128787A JP S56128787 A JPS56128787 A JP S56128787A JP 3024680 A JP3024680 A JP 3024680A JP 3024680 A JP3024680 A JP 3024680A JP S56128787 A JPS56128787 A JP S56128787A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound shown
- cephalosporin derivative
- preparation
- heterocyclic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
NEW MATERIAL:A cephalosporin derivative shown by the formula I [R1 is H, NH2, NHCOR4(R4 is NH2 or 1W5C alkyl optionally substituted by NH2); R2 is H, COOR5(R5 is H or 1W5C alkyl); R3 is heterocyclic, heterocyclic thio, or azide, m and n are or 2], and its pharmaceutically acceptable salt or ester.
EXAMPLE: 7-(3D,L-3-Amino-3-carboxy)propylthioacetamide-3-(1-methyl-1H-tetrazole-5-yl)thiomethyl-3-cephem-4-carboxylic acid.
USE: An antimicrobial agent. Effective against wide range of bacteria, especially having high activities in an organism.
PROCESS: For example, a compound shown by the formula II (X is halogen) is reacted with a compound shown by the formula III, to give a compound shown by the formula I. The reaction is carried out preferably in a solvent, e.g., water, etc. in the presence of an acid binder.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3024680A JPS56128787A (en) | 1980-03-12 | 1980-03-12 | Cephalosporin derivative and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3024680A JPS56128787A (en) | 1980-03-12 | 1980-03-12 | Cephalosporin derivative and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56128787A true JPS56128787A (en) | 1981-10-08 |
JPH0129798B2 JPH0129798B2 (en) | 1989-06-14 |
Family
ID=12298345
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP3024680A Granted JPS56128787A (en) | 1980-03-12 | 1980-03-12 | Cephalosporin derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56128787A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0727426A2 (en) * | 1995-02-15 | 1996-08-21 | Bristol-Myers Squibb Company | Cephalosporin derivatives |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6210513A (en) * | 1985-07-09 | 1987-01-19 | Matsushita Electric Ind Co Ltd | Cooking unit |
-
1980
- 1980-03-12 JP JP3024680A patent/JPS56128787A/en active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6210513A (en) * | 1985-07-09 | 1987-01-19 | Matsushita Electric Ind Co Ltd | Cooking unit |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0727426A2 (en) * | 1995-02-15 | 1996-08-21 | Bristol-Myers Squibb Company | Cephalosporin derivatives |
EP0727426A3 (en) * | 1995-02-15 | 1996-10-23 | Bristol Myers Squibb Co | Cephalosporin derivatives |
Also Published As
Publication number | Publication date |
---|---|
JPH0129798B2 (en) | 1989-06-14 |
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