JPS5759896A - Production of thiazolineazetidinone derivative - Google Patents

Production of thiazolineazetidinone derivative

Info

Publication number
JPS5759896A
JPS5759896A JP55137022A JP13702280A JPS5759896A JP S5759896 A JPS5759896 A JP S5759896A JP 55137022 A JP55137022 A JP 55137022A JP 13702280 A JP13702280 A JP 13702280A JP S5759896 A JPS5759896 A JP S5759896A
Authority
JP
Japan
Prior art keywords
halogen
derivative
thiazolinazetidinone
conducted
organic solvent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP55137022A
Other languages
Japanese (ja)
Other versions
JPS6221072B2 (en
Inventor
Shigeru Torii
Kenji Uneyama
Hideo Tanaka
Junzo Nogami
Norio Saito
Takashi Shiroi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Chemical Co Ltd
Otsuka Kagaku Yakuhin KK
Original Assignee
Otsuka Chemical Co Ltd
Otsuka Kagaku Yakuhin KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Chemical Co Ltd, Otsuka Kagaku Yakuhin KK filed Critical Otsuka Chemical Co Ltd
Priority to JP55137022A priority Critical patent/JPS5759896A/en
Publication of JPS5759896A publication Critical patent/JPS5759896A/en
Publication of JPS6221072B2 publication Critical patent/JPS6221072B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)

Abstract

PURPOSE: The electrolytic reaction of a specific thiazolinazetidinone derivative is conducted in a water-organic solvent mixture system in the presence of halogen salt or acid to produce the titled compound used as an intermediate of antibiotics efficiently in a short time in high yield.
CONSTITUTION: The electrolytic reaction of a thiazolinazetidinone derivative of formulaI(R1 is alkyl, alkenyl, alkoxy, aryl, acyl; R2 is carboxyl, protected carboxyl) such as 2-(3-benzyl-7-oxo-4-thio-2,6-diazabicyclo[3,2,0]hept-2-ene-6-yl)-3- methyl-3-butenoic methyl ester, is conducted in a water-organic solvent (such as methylene chloride) mixture system in the presence of at least one selected from halogen salts such as sodium chloride and halogen acids such as hydrochloric acid to give the objective compound of formula II (X is halogen).
COPYRIGHT: (C)1982,JPO&Japio
JP55137022A 1980-09-30 1980-09-30 Production of thiazolineazetidinone derivative Granted JPS5759896A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP55137022A JPS5759896A (en) 1980-09-30 1980-09-30 Production of thiazolineazetidinone derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55137022A JPS5759896A (en) 1980-09-30 1980-09-30 Production of thiazolineazetidinone derivative

Publications (2)

Publication Number Publication Date
JPS5759896A true JPS5759896A (en) 1982-04-10
JPS6221072B2 JPS6221072B2 (en) 1987-05-11

Family

ID=15189000

Family Applications (1)

Application Number Title Priority Date Filing Date
JP55137022A Granted JPS5759896A (en) 1980-09-30 1980-09-30 Production of thiazolineazetidinone derivative

Country Status (1)

Country Link
JP (1) JPS5759896A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3216256A1 (en) 1981-05-01 1982-11-18 Otsuka Kagaku Yakuhin K.K., Osaka THIAZOLINOAZETIDINE DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF
WO1984001152A1 (en) * 1982-09-24 1984-03-29 Otsuka Kagaku Yakuhin Azetidinone compounds
US4789740A (en) * 1983-03-10 1988-12-06 Otsuka Kagaku Yakuhin Kabushiki Kaisha Halogenation process for preparing 2-(oxoazetidinyl)-3-chloromethyl-3-butenoate

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3216256A1 (en) 1981-05-01 1982-11-18 Otsuka Kagaku Yakuhin K.K., Osaka THIAZOLINOAZETIDINE DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF
WO1984001152A1 (en) * 1982-09-24 1984-03-29 Otsuka Kagaku Yakuhin Azetidinone compounds
JPS5955888A (en) * 1982-09-24 1984-03-31 Otsuka Chem Co Ltd Azetidinone compound
JPS6343399B2 (en) * 1982-09-24 1988-08-30 Ootsuka Kagaku Kk
US4789740A (en) * 1983-03-10 1988-12-06 Otsuka Kagaku Yakuhin Kabushiki Kaisha Halogenation process for preparing 2-(oxoazetidinyl)-3-chloromethyl-3-butenoate

Also Published As

Publication number Publication date
JPS6221072B2 (en) 1987-05-11

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