|
US3325353A
(en)
|
1965-06-07 |
1967-06-13 |
Monsanto Co |
Gastropodicidally effective 2', 5-dichloro-4'-cyanosalicylanilides
|
|
US3975532A
(en)
|
1973-06-14 |
1976-08-17 |
Ici United States Inc. |
Hexahydro-1H-furo(3,4-c) pyrrole compounds for treating pain
|
|
DE2853220A1
(de)
|
1978-12-09 |
1980-07-03 |
Hoechst Ag |
Neue amino-pyrimidin-carbanilide, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und ihre verwendung
|
|
US4507481A
(en)
|
1983-07-29 |
1985-03-26 |
Pennwalt Corporation |
Pyrrolo[1,2-a]imidazoles and imidazo[1,2-a]pyridines
|
|
WO1987002367A2
(en)
|
1985-10-18 |
1987-04-23 |
The Upjohn Company |
Cyclic hydrocarbons with an aminoalkyl sidechain
|
|
US5656644A
(en)
|
1994-07-20 |
1997-08-12 |
Smithkline Beecham Corporation |
Pyridyl imidazoles
|
|
EP0630644A4
(en)
|
1992-11-16 |
1996-02-28 |
Leonidov Nikolai B |
ANTIMICROBIAL AND INTERFERON INDUCING PHARMACEUTICAL COMPOUND.
|
|
GB9315595D0
(en)
|
1993-07-28 |
1993-09-08 |
Res Inst Medicine Chem |
New compounds
|
|
MXPA99008417A
(es)
|
1997-03-11 |
2005-02-03 |
Searle & Co |
Terapia de combinacion que emplaza benzotiepinas inhibidoras de transporte de acido biliar ileal e inhibidores de hmg co-a reductasa.
|
|
US6420338B1
(en)
|
1997-06-13 |
2002-07-16 |
New York University Medical Center |
Inhibition of the Src kinase family pathway as a method of treating HBV infection and hepatocellular carcinoma
|
|
FR2765577A1
(fr)
|
1997-07-02 |
1999-01-08 |
Hoechst Schering Agrevo Sa |
Nouveaux amides aromatiques, leur procede de preparation et leur application comme pesticides
|
|
GB9805520D0
(en)
|
1998-03-17 |
1998-05-13 |
Zeneca Ltd |
Chemical compounds
|
|
DE19817262A1
(de)
|
1998-04-18 |
1999-10-21 |
Bayer Ag |
Neue 2-heterocyclisch substituierte Dihydropyrimidine
|
|
US6525069B1
(en)
|
1998-12-18 |
2003-02-25 |
Bristol-Myers Squibb Pharma Co. |
N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
|
|
ATE538794T1
(de)
|
1999-01-13 |
2012-01-15 |
Bayer Healthcare Llc |
Gamma carboxyarylsubstituierte diphenylharnstoffverbindungen als p38 kinasehemmer
|
|
AU5636900A
(en)
|
1999-06-30 |
2001-01-31 |
Merck & Co., Inc. |
Src kinase inhibitor compounds
|
|
DE10012549A1
(de)
|
2000-03-15 |
2001-09-20 |
Bayer Ag |
Arzneimittel gegen virale Erkrankungen
|
|
DE10012823A1
(de)
|
2000-03-16 |
2001-09-20 |
Bayer Ag |
Arzneimittel gegen virale Erkrankungen
|
|
DE10013126A1
(de)
|
2000-03-17 |
2001-09-20 |
Bayer Ag |
Arzneimittel gegen virale Erkrankungen
|
|
ES2330719T3
(es)
|
2000-12-28 |
2009-12-15 |
SHIONOGI & CO., LTD. |
Derivados de 2-piridona con afinidad para el receptor cannabinoide de tipo 2.
|
|
DE10109856A1
(de)
|
2001-03-01 |
2002-09-05 |
Bayer Ag |
Arzneimittel gegen virale Erkrankungen
|
|
US7312214B2
(en)
|
2002-05-10 |
2007-12-25 |
Bristol-Myers Squibb Company |
1, 1-disubstituted cycloalkyl derivatives as factor Xa inhibitors
|
|
CA2493625A1
(en)
|
2002-07-25 |
2004-02-19 |
Pharmacia Italia S.P.A. |
Bicyclo-pyrazoles active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
|
|
US20050113450A1
(en)
|
2002-08-23 |
2005-05-26 |
Atli Thorarensen |
Antibacterial agents
|
|
US20040209930A1
(en)
|
2002-10-02 |
2004-10-21 |
Carboni Joan M. |
Synergistic methods and compositions for treating cancer
|
|
DE10257358A1
(de)
|
2002-12-09 |
2004-07-08 |
Bayer Healthcare Ag |
Substituierte Pyrrole
|
|
US7232825B2
(en)
|
2003-05-02 |
2007-06-19 |
Guoqing P Chen |
Phenylaminopyrimidine derivatives and methods of use
|
|
EP1663227A2
(en)
|
2003-09-10 |
2006-06-07 |
Synta Pharmaceuticals Corporation |
Dihydropyridine compounds for treating or preventing metabolic disorders
|
|
DK1696898T3
(en)
|
2003-12-02 |
2016-02-22 |
Univ Ohio State Res Found |
ZN2 + -CHELATING DESIGN-BASED SHORT-CHAIN FAT ACIDS AS AN UNKNOWN CLASS OF HISTONDEACETYLASE INHIBITORS
|
|
EP1771169A1
(en)
|
2004-07-14 |
2007-04-11 |
PTC Therapeutics, Inc. |
Methods for treating hepatitis c
|
|
WO2006033995A2
(en)
|
2004-09-16 |
2006-03-30 |
Valeant Research And Development |
Thiazolidin-4-ones having anti-hepatitis b activity
|
|
UY29300A1
(es)
|
2004-12-22 |
2006-07-31 |
Astrazeneca Ab |
Compuestos quimicos
|
|
EA200800321A1
(ru)
|
2005-07-14 |
2008-06-30 |
Такеда Сан Диего, Инк. |
Ингибиторы гистондеацетилазы
|
|
JP5261176B2
(ja)
|
2005-08-16 |
2013-08-14 |
アイカジェン， インコーポレイテッド |
電位作動型ナトリウムチャンネル阻害剤
|
|
US20070219239A1
(en)
|
2006-02-10 |
2007-09-20 |
Mjalli Adnan M |
Nitrogen-containing heterocycle derivatives, pharmaceutical compositions, and methods of use thereof as antiviral agents
|
|
WO2008042639A1
(en)
|
2006-10-02 |
2008-04-10 |
Irm Llc |
Compounds and compositions as protein kinase inhibitors
|
|
JP2008184403A
(ja)
|
2007-01-29 |
2008-08-14 |
Japan Health Science Foundation |
新規ｃ型肝炎ウイルス阻害剤
|
|
WO2008120759A1
(ja)
|
2007-03-30 |
2008-10-09 |
Japan Tobacco Inc. |
ウレア化合物およびその用途
|
|
EP2152688A1
(en)
|
2007-05-04 |
2010-02-17 |
Irm Llc |
Compounds and compositions as c-kit and pdgfr kinase inhibitors
|
|
TWI394575B
(zh)
|
2007-07-09 |
2013-05-01 |
Golden Biotechnology Corp |
Application of Cynanchum auranthone Cyclohexenone Compounds in the Preparation of Drugs for the Suppression of Hepatitis B Virus
|
|
CA2693588C
(en)
|
2007-07-13 |
2015-11-17 |
Icagen, Inc. |
Sodium channel inhibitors
|
|
CA2695071A1
(en)
|
2007-08-02 |
2009-02-05 |
F. Hoffmann-La Roche Ag |
The use of benzamide derivatives for the treatment of cns disorders
|
|
MX2010005356A
(es)
|
2007-11-16 |
2010-05-27 |
Schering Corp |
Derivados de indol 3-heterociclico sustituidos y metodos de uso de los mismos.
|
|
WO2009131065A1
(ja)
|
2008-04-24 |
2009-10-29 |
萬有製薬株式会社 |
アリールスルホニル誘導体を有効成分とする長鎖脂肪酸伸長酵素阻害剤
|
|
CN102131801B
(zh)
|
2008-06-25 |
2015-04-08 |
福拉姆医药股份有限公司 |
1,2-二取代的杂环化合物
|
|
JP2010030970A
(ja)
|
2008-07-31 |
2010-02-12 |
Bayer Cropscience Ag |
殺虫性ベンゼンジカルボキサミド誘導体
|
|
US8101643B2
(en)
|
2009-02-27 |
2012-01-24 |
Enanta Pharmaceuticals, Inc. |
Benzimidazole derivatives
|
|
WO2010123139A1
(ja)
|
2009-04-24 |
2010-10-28 |
持田製薬株式会社 |
スルファモイル基を有するアリールカルボキサミド誘導体
|
|
PE20121118A1
(es)
|
2009-05-12 |
2012-09-05 |
Romark Lab Lc |
Compuestos de haloalquil heteroaril benzamida
|
|
WO2011008597A1
(en)
|
2009-07-14 |
2011-01-20 |
Schering Corporation |
Dihydroimidazoisoquinoline derivatives useful as pde10 inhibitors
|
|
US8377970B2
(en)
|
2009-10-08 |
2013-02-19 |
Rhizen Pharmaceuticals Sa |
Modulators of calcium release-activated calcium channel
|
|
CN102093320B
(zh)
|
2009-12-09 |
2013-08-28 |
扬子江药业集团上海海尼药业有限公司 |
一种可溶性环氧化物水解酶抑制剂
|
|
WO2011088561A1
(en)
|
2010-01-20 |
2011-07-28 |
University Of Manitoba |
Anti-viral compounds and compositions
|
|
US20110281950A1
(en)
|
2010-05-11 |
2011-11-17 |
Baiocchi Robert A |
Compositions and methods for reducing proliferation and viability of lymphoblastoid cells
|
|
WO2011151651A1
(en)
|
2010-06-03 |
2011-12-08 |
Arrow Therapeutics Limited |
Benzodiazepine compounds useful for the treatment of hepatitis c
|
|
EP3085368A1
(en)
|
2011-07-01 |
2016-10-26 |
Baruch S. Blumberg Institute |
Sulfamoylbenzamide derivatives as antiviral agents against hbv infection
|
|
WO2013096744A1
(en)
|
2011-12-21 |
2013-06-27 |
Novira Therapeutics, Inc. |
Hepatitis b antiviral agents
|
|
EA026977B1
(ru)
|
2012-01-06 |
2017-06-30 |
Янссен Сайенсиз Айрлэнд Юси |
4,4-дизамещенные 1,4-дигидропиримидины и их применение в качестве лекарственных препаратов для лечения гепатита b
|
|
DK2803662T3
(en)
|
2012-01-13 |
2017-05-01 |
Nippon Chemiphar Co |
P2X4 receptor antagonist
|
|
CN104822267B
(zh)
|
2012-02-29 |
2018-01-23 |
巴鲁克·S·布伦博格研究所 |
乙型肝炎病毒共价闭合环状dna形成的抑制剂及其使用方法
|
|
US20130267517A1
(en)
|
2012-03-31 |
2013-10-10 |
Hoffmann-La Roche Inc. |
Novel 4-methyl-dihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection
|
|
EP2831060B1
(en)
|
2012-03-31 |
2016-05-04 |
F.Hoffmann-La Roche Ag |
Novel 4-methyl-dihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection
|
|
WO2013163404A1
(en)
|
2012-04-27 |
2013-10-31 |
The Uab Research Foundation |
TREATING VIRAL INFECTIONS HAVING VIRAL RNAs TRANSLATED BY A NON-IRES MEDIATED MECHANISM
|
|
US20130309196A1
(en)
|
2012-05-16 |
2013-11-21 |
Gilead Sciences, Inc. |
Antiviral compounds
|
|
SG11201407970VA
(en)
|
2012-06-01 |
2014-12-30 |
Univ Drexel |
Modulation of hepatitis b virus cccdna transcription
|
|
CN103626752B
(zh)
|
2012-08-24 |
2015-08-12 |
广东东阳光药业有限公司 |
二氢嘧啶类化合物及其在药物中的应用
|
|
EA038942B1
(ru)
|
2012-08-28 |
2021-11-12 |
Янссен Сайенсиз Айрлэнд Юси |
Сульфамоил-ариламиды и их применение в качестве лекарственных препаратов для лечения гепатита b
|
|
MX2015002954A
(es)
|
2012-09-10 |
2015-06-05 |
Hoffmann La Roche |
Nuevas 6-aminoacido-heteroarilhidropirimidinas para el tratamiento y profilaxis de la infeccion del virus de la hepatitis b.
|
|
PT2912019T
(pt)
|
2012-10-25 |
2021-05-25 |
Tetra Discovery Partners Llc |
Inibidores heteroarilo da pde4
|
|
CN105209031A
(zh)
|
2012-12-27 |
2015-12-30 |
德雷克塞尔大学 |
针对hbv感染的新型抗病毒剂
|
|
TWI648274B
(zh)
|
2013-02-15 |
2019-01-21 |
英商葛蘭素史克智慧財產發展有限公司 |
作為激酶抑制劑之雜環醯胺類 （二）
|
|
EA035500B1
(ru)
|
2013-05-17 |
2020-06-25 |
Янссен Сайенсиз Айрлэнд Юси |
Производные сульфамоилтиофенамида и их применение в качестве медикаментов для лечения гепатита b
|
|
TWI651300B
(zh)
|
2013-05-17 |
2019-02-21 |
健生科學愛爾蘭無限公司 |
胺磺醯基吡咯醯胺衍生物及其作為用於治療ｂ型肝炎藥物的用途
|
|
CN105209470B
(zh)
|
2013-05-17 |
2018-02-06 |
豪夫迈·罗氏有限公司 |
用于治疗和预防乙型肝炎病毒感染的6‑桥连的杂芳基二氢嘧啶
|
|
JP6748431B2
(ja)
|
2013-07-12 |
2020-09-02 |
京都ケミカル株式会社 |
抗菌剤、袋入り抗菌剤およびシート型抗菌剤
|
|
AR098414A1
(es)
|
2013-11-14 |
2016-05-26 |
Bristol Myers Squibb Co |
PIPERAZINAS DE PIRAZOLO SUSTITUIDO COMO INHIBIDORES DE CASEÍNA QUINASA 1 d/e
|
|
RU2678990C1
(ru)
|
2013-11-19 |
2019-02-05 |
Саншайн Лейк Фарма Ко., Лтд. |
Соединения дигидропиримидина и их применение в фармацевтических препаратах
|
|
SG11201601813UA
(en)
|
2013-11-27 |
2016-04-28 |
Sunshine Lake Pharma Co Ltd |
Processes for preparing dihydropyrimidine derivatives and intermediates thereof
|
|
WO2015103756A1
(en)
|
2014-01-09 |
2015-07-16 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
US9169212B2
(en)
|
2014-01-16 |
2015-10-27 |
Novira Therapeutics, Inc. |
Azepane derivatives and methods of treating hepatitis B infections
|
|
EA201691261A1
(ru)
|
2014-01-30 |
2016-11-30 |
Ф. Хоффманн-Ля Рош Аг |
Новые дигидрохинолизиноны для лечения и профилактики инфекции, вызванной вирусом гепатита b
|
|
JP6306750B2
(ja)
|
2014-03-07 |
2018-04-04 |
エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ |
Ｂ型肝炎ウイルス感染症の治療および予防のための新規な６−縮合ヘテロアリールジヒドロピリミジン
|
|
SG11201605896WA
(en)
|
2014-03-28 |
2016-08-30 |
Sunshine Lake Pharma Co Ltd |
Dihydropyrimidine compounds and their application in pharmaceuticals
|
|
RU2016146365A
(ru)
|
2014-05-13 |
2018-06-19 |
Ф. Хоффманн-Ля Рош Аг |
Новые дигидрохинолизиноны для лечения и профилактики заражения вирусом гепатита b
|
|
BR112016028000B1
(pt)
|
2014-05-30 |
2022-05-17 |
Qilu Pharmaceutical Co., Ltd |
Derivado de alça de di-hidropirimido como um inibidor de hbv
|
|
CN107001283B
(zh)
|
2014-07-31 |
2021-05-25 |
国家健康与医学研究院 |
Flt3受体拮抗剂
|
|
JP6506836B2
(ja)
|
2014-08-14 |
2019-04-24 |
エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ |
Ｂ型肝炎ウイルス感染症の処置および予防のための新規ピリダゾンおよびトリアジノン
|
|
WO2016025933A2
(en)
|
2014-08-15 |
2016-02-18 |
Ptc Therapeutics, Inc. |
Substituted polycyclic antibacterial compounds
|
|
US9637485B2
(en)
|
2014-11-03 |
2017-05-02 |
Hoffmann-La Roche Inc. |
6,7-dihydrobenzo[a]quinolizin-2-one derivatives for the treatment and prophylaxis of hepatitis B virus infection
|
|
WO2016089990A1
(en)
|
2014-12-02 |
2016-06-09 |
Novira Therapeutics, Inc. |
Sulfide alkyl and pyridyl reverse sulfonamide compounds for hbv treatment
|
|
RU2742305C2
(ru)
|
2014-12-30 |
2021-02-04 |
Новира Терапьютикс, Инк. |
Производные и способы лечения инфекций гепатита в
|
|
WO2016107832A1
(en)
|
2014-12-30 |
2016-07-07 |
F. Hoffmann-La Roche Ag |
Novel tetrahydropyridopyrimidines and tetrahydropyridopyridines for the treatment and prophylaxis of hepatitis b virus infection
|
|
CN107207505B
(zh)
|
2015-02-11 |
2018-12-14 |
豪夫迈·罗氏有限公司 |
治疗和预防乙型肝炎病毒感染的 2-氧代-6,7-二氢苯并[a]喹嗪-3-甲酸衍生物
|
|
US10442788B2
(en)
|
2015-04-01 |
2019-10-15 |
Enanta Pharmaceuticals, Inc. |
Hepatitis B antiviral agents
|
|
RU2595038C1
(ru)
|
2015-04-03 |
2016-08-20 |
Виктор Вениаминович Тец |
Лекарственное средство с противовирусной активностью (варианты)
|
|
WO2016177655A1
(en)
|
2015-05-04 |
2016-11-10 |
F. Hoffmann-La Roche Ag |
Tetrahydropyridopyrimidines and tetrahydropyridopyridines as inhibitors of hbsag (hbv surface antigen) and hbv dna production for the treatment of hepatitis b virus infections
|
|
US10738035B2
(en)
|
2015-05-13 |
2020-08-11 |
Enanta Pharmaceuticals, Inc. |
Hepatitis B antiviral agents
|
|
US10179131B2
(en)
|
2015-07-13 |
2019-01-15 |
Enanta Pharmaceuticals, Inc. |
Hepatitis B antiviral agents
|
|
JP6598974B2
(ja)
|
2015-07-21 |
2019-10-30 |
エフ．ホフマン−ラ ロシュ アーゲー |
Ｂ型肝炎ウイルス感染症の治療および予防のための新規な三環式４−ピリドン−３−カルボン酸誘導体
|
|
US10301255B2
(en)
|
2015-07-22 |
2019-05-28 |
Enanta Pharmaceuticals, Inc. |
Hepatitis B antiviral agents
|
|
JP6506880B2
(ja)
|
2015-07-27 |
2019-04-24 |
エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ |
Ｂ型肝炎ウィルス感染症の治療および予防のための新規な四環式４−オキソ−ピリジン−３−カルボン酸誘導体
|
|
JP6559324B2
(ja)
|
2015-07-28 |
2019-08-14 |
エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ |
Ｂ型肝炎ウイルス感染の治療及び予防用の新規６，７−ジヒドロピリド［２，１−ａ］フタラジン−２−オン類
|
|
WO2017061466A1
(ja)
|
2015-10-05 |
2017-04-13 |
富山化学工業株式会社 |
抗ｂ型肝炎ウイルス剤
|
|
ES2794639T3
(es)
|
2015-11-04 |
2020-11-18 |
Qilu Pharmaceutical Co Ltd |
Forma cristalina, método de preparación y compuesto intermedio de compuesto con anillo dihidropirido
|
|
WO2017136403A1
(en)
|
2016-02-02 |
2017-08-10 |
Enanta Pharmaceuticals, Inc. |
Hepatitis b antiviral agents
|
|
US20200270265A1
(en)
|
2016-02-19 |
2020-08-27 |
Novartis Ag |
Tetracyclic pyridone compounds as antivirals
|
|
JP6904970B2
(ja)
|
2016-03-07 |
2021-07-21 |
エナンタ ファーマシューティカルズ インコーポレイテッド |
Ｂ型肝炎抗ウイルス剤
|
|
ES2881776T3
(es)
*
|
2016-03-08 |
2021-11-30 |
Novartis Ag |
Compuestos tricíclicos útiles para tratar las infecciones por ortomixovirus
|
|
HUE064145T2
(hu)
|
2016-04-15 |
2024-03-28 |
Epizyme Inc |
Amin-szubsztituált aril- vagy heteroaril vegyületek, mint EHMT1 és EHMT2 inhibitorok
|
|
BR102017010009A2
(pt)
|
2016-05-27 |
2017-12-12 |
Gilead Sciences, Inc. |
Compounds for the treatment of hepatitis b virus infection
|
|
CN109843296A
(zh)
|
2016-06-10 |
2019-06-04 |
英安塔制药有限公司 |
乙型肝炎抗病毒药剂
|
|
CA3027008C
(en)
|
2016-06-10 |
2021-02-09 |
Les Laboratoires Servier |
(hetero)aryl-substituted-piperidinyl derivatives, a process for their preparation and pharmaceutical compositions containing them
|
|
AR108586A1
(es)
|
2016-06-10 |
2018-09-05 |
Lilly Co Eli |
Compuestos de 2,3-dihidro-1h-indol
|
|
FR3052452B1
(fr)
|
2016-06-10 |
2018-06-22 |
Les Laboratoires Servier |
Nouveaux derives de piperidinyle, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
WO2017211809A1
(en)
|
2016-06-10 |
2017-12-14 |
Bayer Pharma Aktiengesellschaft |
Radio-pharmaceutical complexes
|
|
WO2017216686A1
(en)
|
2016-06-16 |
2017-12-21 |
Novartis Ag |
8,9-fused 2-oxo-6,7-dihydropyrido-isoquinoline compounds as antivirals
|
|
WO2017216685A1
(en)
|
2016-06-16 |
2017-12-21 |
Novartis Ag |
Pentacyclic pyridone compounds as antivirals
|
|
CN109414448B
(zh)
|
2016-06-17 |
2021-10-26 |
豪夫迈·罗氏有限公司 |
用于减少PAPD5或PAPD7 mRNA治疗乙型肝炎感染的核酸分子
|
|
CN109311880B
(zh)
|
2016-06-29 |
2021-09-03 |
豪夫迈·罗氏有限公司 |
用于治疗和预防乙型肝炎病毒感染的新的四氢吡啶并嘧啶类化合物
|
|
WO2018001944A1
(en)
|
2016-06-29 |
2018-01-04 |
F. Hoffmann-La Roche Ag |
Novel dihydropyrrolopyrimidines for the treatment and prophylaxis of hepatitis b virus infection
|
|
WO2018019297A1
(zh)
|
2016-07-29 |
2018-02-01 |
银杏树药业(苏州)有限公司 |
异喹啉酮类化合物及其制备抗病毒药物的应用
|
|
CN110156774A
(zh)
|
2016-07-29 |
2019-08-23 |
新波制药有限公司 |
用于治疗hbv感染的新颖治疗剂
|
|
TW201811788A
(zh)
|
2016-09-09 |
2018-04-01 |
瑞士商諾華公司 |
作為抗病毒劑之多環吡啶酮化合物
|
|
WO2018073753A1
(en)
*
|
2016-10-18 |
2018-04-26 |
Novartis Ag |
Fused tetracyclic pyridone compounds as antivirals
|
|
CN110088104B
(zh)
|
2016-11-03 |
2022-04-12 |
豪夫迈·罗氏有限公司 |
用于治疗和预防乙型肝炎病毒感染的四氢吡啶并嘧啶化合物
|
|
US11124495B2
(en)
|
2016-11-03 |
2021-09-21 |
Hoffmann-La Roche, Inc. |
Tetrahydroisoquinolines and terahydronaphthyridines for the treatment of hepatitis B virus infection
|
|
CN110088103B
(zh)
|
2016-11-03 |
2022-04-12 |
豪夫迈·罗氏有限公司 |
用于治疗和预防乙型肝炎病毒感染的新的四氢吡啶并嘧啶化合物
|
|
TWI794190B
(zh)
|
2016-11-07 |
2023-03-01 |
加拿大商愛彼特生物製藥公司 |
含有取代的吡啶酮之三環化合物及其使用方法
|
|
WO2018087345A1
(en)
|
2016-11-14 |
2018-05-17 |
F. Hoffmann-La Roche Ag |
COMBINATION THERAPY OF AN HBsAg INHIBITOR, A NUCLEOS(T)IDE ANALOGUE AND AN INTERFERON
|
|
PT3565806T
(pt)
|
2017-01-06 |
2022-05-19 |
Rivus Pharmaceuticals Inc |
Novos derivados de fenilo
|
|
CN106810548B
(zh)
|
2017-01-13 |
2019-02-15 |
苏州爱科百发生物医药技术有限公司 |
一种二氢异喹啉类化合物
|
|
UY37581A
(es)
|
2017-02-02 |
2018-08-31 |
Gilead Sciences Inc |
Compuestos para el tratamiento de la infección por virus de la hepatitis b
|
|
WO2018154466A1
(en)
|
2017-02-21 |
2018-08-30 |
Glaxosmithkline Intellectual Property Development Limited |
Dihydroquinolizinones as antivirals
|
|
CN106928245B
(zh)
|
2017-03-06 |
2019-06-11 |
河南春风医药科技有限公司 |
一种喹嗪酮类化合物及其制备方法和应用
|
|
CN106928215B
(zh)
|
2017-03-06 |
2019-03-22 |
河南春风医药科技有限公司 |
一种喹嗪酮类化合物的制备方法
|
|
BR112019018650B1
(pt)
|
2017-03-09 |
2021-12-14 |
Fujian Cosunter Pharmaceutical Co., Ltd |
Composto inibidor de antígeno de superfície de vírus da hepatite b, composição farmacêutica e seus usos
|
|
TW201841911A
(zh)
|
2017-03-31 |
2018-12-01 |
日商富士軟片股份有限公司 |
４－吡啶酮化合物或其鹽、包含４－吡啶酮化合物之藥物組成物及劑
|
|
CN108727378A
(zh)
|
2017-04-19 |
2018-11-02 |
银杏树药业(苏州)有限公司 |
新型异喹啉类化合物及其医药用途
|
|
AR111419A1
(es)
|
2017-04-27 |
2019-07-10 |
Novartis Ag |
Compuestos fusionados de indazol piridona como antivirales
|
|
CN108794481A
(zh)
|
2017-04-28 |
2018-11-13 |
齐鲁制药有限公司 |
化合物的多晶型、其制备方法和用途
|
|
CN110066278B
(zh)
|
2017-06-01 |
2021-06-08 |
广东东阳光药业有限公司 |
稠合三环类化合物及其在药物中的应用
|
|
US10952978B2
(en)
|
2017-08-28 |
2021-03-23 |
Enanta Pharmaceuticals, Inc. |
Hepatitis B antiviral agents
|
|
SI3692040T1
(sl)
|
2017-10-05 |
2023-05-31 |
Glaxosmithkline Intellectual Property Development Limited |
Kemijske spojine
|
|
EP3710455A1
(en)
|
2017-11-17 |
2020-09-23 |
Novartis AG |
Novel dihydroisoxazole compounds and their use for the treatment of hepatitis b
|
|
EP3694856B1
(en)
|
2017-11-22 |
2023-10-25 |
Sunshine Lake Pharma Co., Ltd. |
Fused tricyclic compounds and uses thereof in medicine
|
|
GB201720163D0
(en)
|
2017-12-04 |
2018-01-17 |
Galapagos Nv |
Novel compounds and pharmaceutical compositions thereof for the treatment of hepatitis B
|
|
TW201936192A
(zh)
|
2017-12-06 |
2019-09-16 |
美商因那塔製藥公司 |
B 型肝炎抗病毒試劑
|
|
TW201927789A
(zh)
|
2017-12-06 |
2019-07-16 |
美商因那塔製藥公司 |
B型肝炎抗病毒試劑
|
|
JP2021507906A
(ja)
|
2017-12-20 |
2021-02-25 |
ノバルティス アーゲー |
抗ウイルス剤としての融合三環式ピラゾロ−ジヒドロピラジニル−ピリドン化合物
|
|
EP3732177B1
(en)
|
2017-12-28 |
2021-11-17 |
F. Hoffmann-La Roche AG |
Dihydropyrimidinylthiazole for the treatment and prophylaxis of hepatitis b virus infection
|
|
US11058678B2
(en)
|
2018-01-22 |
2021-07-13 |
Enanta Pharmaceuticals, Inc. |
Substituted heterocycles as antiviral agents
|
|
CN111801331A
(zh)
|
2018-02-28 |
2020-10-20 |
诺华股份有限公司 |
吲哚-2-羰基化合物及其用于治疗乙型肝炎的用途
|
|
WO2019191166A1
(en)
|
2018-03-29 |
2019-10-03 |
Enanta Pharmaceuticals, Inc. |
Hepatitis b antiviral agents
|
|
MX2020011275A
(es)
|
2018-04-25 |
2020-11-13 |
Bayer Ag |
Novedosos compuestos de heteroaril-triazol y hetroaril[-]tetrazol como plaguicidas.
|
|
ES2942443T3
(es)
|
2018-06-05 |
2023-06-01 |
Albireo Ab |
Compuestos de benzotia(di)azepina y su uso como moduladores de ácidos biliares
|
|
UY38383A
(es)
|
2018-09-21 |
2020-04-30 |
Enanta Pharm Inc |
Heterociclos funcionalizados como agentes antivirales
|
|
CN111116577A
(zh)
|
2018-10-30 |
2020-05-08 |
广东东阳光药业有限公司 |
稠合四环类化合物及其在药物中的应用
|
|
US11198693B2
(en)
*
|
2018-11-21 |
2021-12-14 |
Enanta Pharmaceuticals, Inc. |
Functionalized heterocycles as antiviral agents
|
|
TW202033523A
(zh)
|
2019-01-17 |
2020-09-16 |
美商愛彼特生物製藥股份有限公司 |
經取代的多環羧酸、其類似物及使用其之方法
|
|
HUE060905T2
(hu)
|
2019-02-06 |
2023-04-28 |
Albireo Ab |
Benzotiadiazepin vegyületek és azok alkalmazása epesav modulátorként
|
|
ES2955799T3
(es)
|
2019-02-06 |
2023-12-07 |
Albireo Ab |
Compuestos de benzotiazepina y su uso como moduladores de los ácidos biliares
|
|
PE20220168A1
(es)
|
2019-03-15 |
2022-01-28 |
Ionis Pharmaceuticals Inc |
Compuestos y metodos para reducir la expresion de kcnt1
|
|
US11236108B2
(en)
|
2019-09-17 |
2022-02-01 |
Enanta Pharmaceuticals, Inc. |
Functionalized heterocycles as antiviral agents
|
|
TWI877263B
(zh)
|
2019-12-04 |
2025-03-21 |
瑞典商艾爾比瑞歐公司 |
苯并噻二氮呯化合物及其作為膽酸調節劑之用途
|
|
AR120679A1
(es)
|
2019-12-04 |
2022-03-09 |
Albireo Ab |
Compuestos de benzoti(di)azepina y su uso como moduladores ácido biliar
|
|
AR120676A1
(es)
|
2019-12-04 |
2022-03-09 |
Albireo Ab |
Compuestos de benzoti(di)azepina y su uso como ácido biliar
|
|
TWI877262B
(zh)
|
2019-12-04 |
2025-03-21 |
瑞典商艾爾比瑞歐公司 |
苯并噻氮呯化合物及其作為膽酸調節劑之用途
|
|
TWI867107B
(zh)
|
2019-12-04 |
2024-12-21 |
瑞典商艾爾比瑞歐公司 |
苯并噻(二)氮呯化合物及其作為膽酸調節劑之用途
|
|
WO2022029101A1
(en)
|
2020-08-03 |
2022-02-10 |
Albireo Ab |
Benzothia(di)azepine compounds and their use as bile acid modulators
|
|
JP2024500309A
(ja)
|
2020-12-04 |
2024-01-09 |
アルビレオ エービー |
ベンゾチア（ジ）アゼピン化合物および胆汁酸モジュレータとしてのその使用
|
|
KR102265708B1
(ko)
|
2021-03-19 |
2021-06-16 |
(주)프레이저테라퓨틱스 |
아미노산 유도체, 이의 제조방법 및 이를 포함하는 b형 간염 또는 d형 간염 치료용 약학적 조성물
|
|
WO2022225035A1
(ja)
|
2021-04-22 |
2022-10-27 |
学校法人愛知医科大学 |
Ｂ型肝炎ウイルスに対する抗ウイルス効果を有する胆汁酸誘導体
|
|
TW202313579A
(zh)
|
2021-06-03 |
2023-04-01 |
瑞典商艾爾比瑞歐公司 |
苯并噻(二)氮呯(benzothia(di)azepine)化合物及其作為膽酸調節劑之用途
|
|
WO2023164183A1
(en)
|
2022-02-25 |
2023-08-31 |
Assembly Biosciences, Inc. |
Benzothia(dia)zepine compounds for treatment of hbv and hdv
|
|
WO2023164179A1
(en)
|
2022-02-25 |
2023-08-31 |
Assembly Biosciences, Inc. |
Benzothia(dia)zepine compounds for treatment of hbv and hdv
|
|
WO2023164186A1
(en)
|
2022-02-25 |
2023-08-31 |
Assembly Biosciences, Inc. |
Benzothia(dia)zepine compounds for treatment of hbv and hdv
|
|
WO2023164181A1
(en)
|
2022-02-25 |
2023-08-31 |
Assembly Biosciences, Inc. |
Benzothia(dia)zepine compounds for treatment of hbv and hdv
|