IL173052A - Nucleic Acid-Lipid Particles Containing Rna Interfering, Preparations Containing and Uses - Google Patents

Nucleic Acid-Lipid Particles Containing Rna Interfering, Preparations Containing and Uses

Info

Publication number
IL173052A
IL173052A IL173052A IL17305206A IL173052A IL 173052 A IL173052 A IL 173052A IL 173052 A IL173052 A IL 173052A IL 17305206 A IL17305206 A IL 17305206A IL 173052 A IL173052 A IL 173052A
Authority
IL
Israel
Prior art keywords
compositions
nucleic acid
same
interfering rna
lipid particles
Prior art date
Application number
IL173052A
Other languages
English (en)
Hebrew (he)
Other versions
IL173052A0 (en
Original Assignee
Protiva Biotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Protiva Biotherapeutics Inc filed Critical Protiva Biotherapeutics Inc
Publication of IL173052A0 publication Critical patent/IL173052A0/en
Publication of IL173052A publication Critical patent/IL173052A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL173052A 2003-07-16 2006-01-10 Nucleic Acid-Lipid Particles Containing Rna Interfering, Preparations Containing and Uses IL173052A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US48814403P 2003-07-16 2003-07-16
US50327903P 2003-09-15 2003-09-15
US52940603P 2003-12-11 2003-12-11
PCT/CA2004/001051 WO2005007196A2 (en) 2003-07-16 2004-07-16 Lipid encapsulated interfering rna

Publications (2)

Publication Number Publication Date
IL173052A0 IL173052A0 (en) 2006-06-11
IL173052A true IL173052A (en) 2015-03-31

Family

ID=34084527

Family Applications (2)

Application Number Title Priority Date Filing Date
IL173052A IL173052A (en) 2003-07-16 2006-01-10 Nucleic Acid-Lipid Particles Containing Rna Interfering, Preparations Containing and Uses
IL237721A IL237721B (en) 2003-07-16 2015-03-12 Lipid-wrapped interfering RNA and uses thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL237721A IL237721B (en) 2003-07-16 2015-03-12 Lipid-wrapped interfering RNA and uses thereof

Country Status (12)

Country Link
US (3) US20050064595A1 (enExample)
EP (2) EP1648519B1 (enExample)
JP (4) JP4951338B2 (enExample)
KR (1) KR101168440B1 (enExample)
CN (1) CN101291653B (enExample)
AU (2) AU2004257373B2 (enExample)
CA (1) CA2532228C (enExample)
ES (1) ES2559828T3 (enExample)
IL (2) IL173052A (enExample)
NZ (1) NZ544637A (enExample)
SG (1) SG190613A1 (enExample)
WO (1) WO2005007196A2 (enExample)

Families Citing this family (437)

* Cited by examiner, † Cited by third party
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CA2532228A1 (en) 2005-01-27
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AU2004257373A1 (en) 2005-01-27
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CA2532228C (en) 2017-02-14
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