|
US6168778B1
(en)
|
1990-06-11 |
2001-01-02 |
Nexstar Pharmaceuticals, Inc. |
Vascular endothelial growth factor (VEGF) Nucleic Acid Ligand Complexes
|
|
US6762290B1
(en)
|
1999-07-29 |
2004-07-13 |
Gilead Sciences, Inc. |
High affinity vascular endothelial growth factor (VEGF) receptor nucleic acid ligands and inhibitors
|
|
US6221839B1
(en)
|
1994-11-14 |
2001-04-24 |
Helsinki University Licensing Ltd. Oy |
FIt4 ligand and methods of use
|
|
US6645933B1
(en)
|
1995-08-01 |
2003-11-11 |
Helsinki University Licensing Ltd. Oy |
Receptor ligand VEGF-C
|
|
US6818220B1
(en)
|
1994-11-14 |
2004-11-16 |
Licentia Ltd. |
Vascular endothelial growth factor C (VEGF-C) protein and gene mutants thereof, and uses thereof
|
|
US6245530B1
(en)
|
1995-08-01 |
2001-06-12 |
Ludwig Institute For Cancer Research |
Receptor ligand
|
|
US6403088B1
(en)
|
1995-08-01 |
2002-06-11 |
Helsinki University Licensing, Ltd. |
Antibodies reactive with VEGF-C, a ligand for the Flt4 receptor tyrosine kinase (VEGFR-3)
|
|
US6130071A
(en)
*
|
1997-02-05 |
2000-10-10 |
Helsinki University Licensing, Ltd. |
Vascular endothelial growth factor C (VEGF-C) ΔCys156 protein and gene, and uses thereof
|
|
US6267958B1
(en)
|
1995-07-27 |
2001-07-31 |
Genentech, Inc. |
Protein formulation
|
|
US6685940B2
(en)
|
1995-07-27 |
2004-02-03 |
Genentech, Inc. |
Protein formulation
|
|
US6361946B1
(en)
|
1997-02-05 |
2002-03-26 |
Licentia Ltd |
Vascular endothelial growth factor C (VEGF-C) protein and gene, mutants thereof, and uses thereof
|
|
US7727761B2
(en)
|
1995-08-01 |
2010-06-01 |
Vegenics Limited |
Vascular endothelial growth factor C (VEGF-C) protein and gene, mutants thereof, and uses thereof
|
|
US7371376B1
(en)
|
1996-10-18 |
2008-05-13 |
Genentech, Inc. |
Anti-ErbB2 antibodies
|
|
US6426335B1
(en)
|
1997-10-17 |
2002-07-30 |
Gilead Sciences, Inc. |
Vascular endothelial growth factor (VEGF) nucleic acid ligand complexes
|
|
US6051698A
(en)
*
|
1997-06-06 |
2000-04-18 |
Janjic; Nebojsa |
Vascular endothelial growth factor (VEGF) nucleic acid ligand complexes
|
|
US7125714B2
(en)
|
1997-02-05 |
2006-10-24 |
Licentia Ltd. |
Progenitor cell materials and methods
|
|
DE69829891T2
(de)
|
1997-04-07 |
2005-10-06 |
Genentech, Inc., South San Francisco |
Anti-VEGF Antikörper
|
|
US6884879B1
(en)
|
1997-04-07 |
2005-04-26 |
Genentech, Inc. |
Anti-VEGF antibodies
|
|
US20070059302A1
(en)
|
1997-04-07 |
2007-03-15 |
Genentech, Inc. |
Anti-vegf antibodies
|
|
US20020032315A1
(en)
|
1997-08-06 |
2002-03-14 |
Manuel Baca |
Anti-vegf antibodies
|
|
DE19744531A1
(de)
*
|
1997-10-09 |
1999-05-27 |
Klaus Dr Rer Nat Bosslet |
Bindemoleküle gegen Rezeptor-Ligand-Komplexe
|
|
US6391311B1
(en)
|
1998-03-17 |
2002-05-21 |
Genentech, Inc. |
Polypeptides having homology to vascular endothelial cell growth factor and bone morphogenetic protein 1
|
|
GB9723780D0
(en)
*
|
1997-11-12 |
1998-01-07 |
Univ Manchester |
Regulation of ocular angiogenesis
|
|
IL137649A
(en)
*
|
1998-02-18 |
2004-08-31 |
Genentech Inc |
Method of adsorption chromatography
|
|
EP1064382B1
(de)
|
1998-03-17 |
2008-08-20 |
Genentech, Inc. |
Zu vegf und bmp1 homologe polypeptide
|
|
EP1579871A1
(de)
|
1998-12-22 |
2005-09-28 |
Genentech, Inc. |
Antagonisten von vaskular-endothelialen Zellwachstumsfaktoren und ihre Anwendung
|
|
DE10008946C1
(de)
|
2000-02-25 |
2001-10-18 |
Basf Coatings Ag |
Verfahren zur Herstellung farb- und/oder effektgebender Mehrschichtlackierungen auf Automobilkarosserien
|
|
EP2792747A1
(de)
|
2000-06-23 |
2014-10-22 |
Genentech, Inc. |
Zusammensetzungen und Verfahren zur Diagnose und Behandlung von Erkrankungen in Verbindung mit Angiogenese
|
|
EP2075253A1
(de)
|
2000-06-23 |
2009-07-01 |
Genentech, Inc. |
Methoden und Verbindungen zur Diagnose und Behandlung von Krankheiten, an denen Angiogenese beteiligt ist
|
|
DE10043405C1
(de)
|
2000-09-04 |
2002-06-27 |
Basf Coatings Ag |
Verfahren zur Herstellung farb- und/oder effektgebender Lackierungen
|
|
DE10130972C1
(de)
|
2001-06-27 |
2002-11-07 |
Basf Coatings Ag |
Verfahren zur Herstellung von Beschichtungen aus thermisch und mit aktinischer Strahlung härtbaren Beschichtungsstoffen und mit dem Verfahren herstellbare Lackierungen
|
|
US20050123925A1
(en)
|
2002-11-15 |
2005-06-09 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
EP1472275B1
(de)
|
2002-02-05 |
2008-12-17 |
Genentech, Inc. |
Proteinaufreinigung
|
|
WO2003068258A1
(en)
*
|
2002-02-15 |
2003-08-21 |
Richard Brunner |
7s immunoglobulin for treatment of choroidal neovascularisation_
|
|
SI1501369T1
(sl)
|
2002-04-26 |
2015-10-30 |
Genentech, Inc. |
Neafinitetno čiščenje proteinov
|
|
RS20150135A1
(sr)
*
|
2003-05-30 |
2015-08-31 |
Genentech Inc. |
Tretman sa anti-vegf antitelima
|
|
US7601341B2
(en)
|
2003-06-05 |
2009-10-13 |
Research Development Foundation |
Vascular endothelial growth factor fusion constructs used to inhibit osteoclastogenesis
|
|
JP4599355B2
(ja)
|
2003-07-28 |
2010-12-15 |
ジェネンテック, インコーポレイテッド |
プロテインaアフィニティークロマトグラフィーの間のプロテインaの浸出の低減
|
|
NZ592039A
(en)
|
2003-08-27 |
2013-03-28 |
Ophthotech Corp |
Combination therapy for the treatment of ocular neovascular disorders
|
|
DE102004027650A1
(de)
|
2004-06-05 |
2006-01-05 |
Basf Coatings Ag |
Verfahren zum Beschichten elektrisch leitfähiger Substrate
|
|
SI1771474T1
(sl)
|
2004-07-20 |
2010-06-30 |
Genentech Inc |
Inhibitorji angiopoetinu podobnega proteina kombinacije in njihova uporaba
|
|
US8604185B2
(en)
|
2004-07-20 |
2013-12-10 |
Genentech, Inc. |
Inhibitors of angiopoietin-like 4 protein, combinations, and their use
|
|
US7655229B2
(en)
|
2004-09-02 |
2010-02-02 |
Chan Andrew C |
Anti-FC-gamma RIIB receptor antibody and uses therefor
|
|
US7662926B2
(en)
|
2004-09-02 |
2010-02-16 |
Genentech, Inc. |
Anti-Fc-gamma receptor antibodies, bispecific variants and uses therefor
|
|
PT1802334E
(pt)
|
2004-10-21 |
2012-11-28 |
Genentech Inc |
Método para tratamento de doenças neovasculares intraoculares
|
|
NZ561763A
(en)
|
2005-03-24 |
2009-02-28 |
Thrombogenics Nv |
Novel anti PLGF antibody
|
|
CA2606989A1
(en)
*
|
2005-04-29 |
2006-11-09 |
Research Development Foundation |
Vascular targeting of ocular neovascularization
|
|
EP1904095B1
(de)
|
2005-06-30 |
2013-05-29 |
VIB, vzw |
Behandlung von leberzirrhose und ihre komplikationen
|
|
WO2007011873A2
(en)
*
|
2005-07-15 |
2007-01-25 |
Genentech, Inc. |
Method for treating intraocular neovascular diseases
|
|
US8168584B2
(en)
|
2005-10-08 |
2012-05-01 |
Potentia Pharmaceuticals, Inc. |
Methods of treating age-related macular degeneration by compstatin and analogs thereof
|
|
UA96139C2
(uk)
|
2005-11-08 |
2011-10-10 |
Дженентек, Інк. |
Антитіло до нейропіліну-1 (nrp1)
|
|
US8101365B2
(en)
|
2006-01-05 |
2012-01-24 |
Genentech, Inc. |
Anti-EphB4 antibodies and methods using same
|
|
RU2451031C2
(ru)
|
2006-01-20 |
2012-05-20 |
Дженентек, Инк. |
Антитела к эфрину в2 и способы их применения
|
|
AR059851A1
(es)
|
2006-03-16 |
2008-04-30 |
Genentech Inc |
Anticuerpos de la egfl7 y metodos de uso
|
|
AU2007319672B2
(en)
|
2006-06-06 |
2011-06-30 |
Genentech, Inc. |
Anti-DLL4 antibodies and methods using same
|
|
FR2902799B1
(fr)
|
2006-06-27 |
2012-10-26 |
Millipore Corp |
Procede et unite de preparation d'un echantillon pour l'analyse microbiologique d'un liquide
|
|
RU2542471C2
(ru)
|
2006-11-15 |
2015-02-20 |
Коуда Терапьютикс, Инк. |
Улучшенные способы и композиции для заживления ран
|
|
US20080248033A1
(en)
|
2006-12-19 |
2008-10-09 |
Genentech, Inc. |
VEGF-specific antagonists for adjuvant and neoadjuvant therapy and the treatment of early stage tumors
|
|
US8163886B2
(en)
|
2006-12-21 |
2012-04-24 |
Emd Millipore Corporation |
Purification of proteins
|
|
US8569464B2
(en)
|
2006-12-21 |
2013-10-29 |
Emd Millipore Corporation |
Purification of proteins
|
|
US8362217B2
(en)
|
2006-12-21 |
2013-01-29 |
Emd Millipore Corporation |
Purification of proteins
|
|
RU2474585C2
(ru)
|
2007-01-22 |
2013-02-10 |
Дженентек, Инк. |
Осаждение и очистка белков полиэлектролитами
|
|
ES2541051T3
(es)
|
2007-05-17 |
2015-07-15 |
Genentech, Inc. |
Estructuras cristalinas de fragmentos de neuropilina y complejos neuropilina-anticuerpo
|
|
CN101754771B
(zh)
|
2007-05-17 |
2015-03-04 |
健泰科生物技术公司 |
抗神经毡蛋白2抗体对肿瘤转移的抑制
|
|
PE20090321A1
(es)
|
2007-06-04 |
2009-04-20 |
Genentech Inc |
Anticuerpos anti-notch1 nrr, metodo de preparacion y composicion farmaceutica
|
|
EP2586788B1
(de)
|
2007-07-09 |
2017-11-29 |
Genentech, Inc. |
Verhindern der Disulfid-Bindungsreduktion während der rekombinanten Herstellung von Polypeptiden
|
|
HUE024877T2
(en)
|
2007-10-30 |
2016-02-29 |
Genentech Inc |
Antibody purification by cation exchange chromatography
|
|
CL2008003302A1
(es)
|
2007-11-09 |
2009-03-06 |
Genentech Inc |
Uso de una proteina de funsion kinasa 1 similar al receptor de activina (alk-1) y fc (alk1.fc) porque sirve para preparar un medicamento contra tumor,cancer o desordenes proliferativos.
|
|
TWI468417B
(zh)
|
2007-11-30 |
2015-01-11 |
Genentech Inc |
抗-vegf抗體
|
|
WO2009151514A1
(en)
|
2008-06-11 |
2009-12-17 |
Millipore Corporation |
Stirred tank bioreactor
|
|
KR20180005753A
(ko)
|
2008-06-25 |
2018-01-16 |
에스바테크 - 어 노바티스 컴파니 엘엘씨 |
Vegf를 억제하는 안정하고 가용성인 항체
|
|
HUE066562T2
(hu)
|
2008-08-14 |
2024-08-28 |
Genentech Inc |
Eljárások szennyezés eltávolítására indigén fehérje kiszorításos ioncserés membrán kromatográfia alkalmazásával
|
|
EP2684570A1
(de)
|
2008-09-10 |
2014-01-15 |
F. Hoffmann-La Roche AG |
Zusammensetzungen und Verfahren zur Prävention des oxidativen Abbaus von Proteinen
|
|
WO2010037864A2
(en)
|
2008-10-02 |
2010-04-08 |
Vib Vzw |
Inhibition of plgf to treat philadelphia chromosome positive leukemia
|
|
AU2009303526B2
(en)
|
2008-10-14 |
2015-01-15 |
Genentech, Inc. |
Immunoglobulin variants and uses thereof
|
|
NZ592591A
(en)
|
2008-11-03 |
2012-04-27 |
Molecular Partners Ag |
Binding proteins comprising ankyrin repeast domains that inhibit the vegf-a receptor interaction
|
|
KR20180117734A
(ko)
|
2008-11-22 |
2018-10-29 |
제넨테크, 인크. |
유방암의 치료를 위한, 화학요법과 조합된 항-vegf 항체의 용도
|
|
US20110020327A1
(en)
|
2008-12-16 |
2011-01-27 |
Millipore Corporation |
Purification of proteins
|
|
DK2370561T3
(da)
|
2008-12-16 |
2019-10-21 |
Emd Millipore Corp |
Omrøringstankreaktor og fremgangsmåde
|
|
CA2746120A1
(en)
|
2008-12-23 |
2010-07-01 |
Genentech, Inc. |
Methods and compositions for diagnostic use in cancer patients
|
|
US8435488B2
(en)
|
2009-02-27 |
2013-05-07 |
Genentech, Inc. |
Methods and compositions for protein labelling
|
|
RU2011149798A
(ru)
|
2009-05-08 |
2013-06-20 |
Дженентек, Инк. |
Гуманизированные анти-egfl7-антитела и способы их применения
|
|
EP2443234B1
(de)
|
2009-06-15 |
2018-08-15 |
Icon Genetics GmbH |
Nicotiana benthamiana-pflanzen mit mangelnder xylosyltransferase-aktivität
|
|
SG177640A1
(en)
|
2009-07-13 |
2012-02-28 |
Genentech Inc |
Diagnostic methods and compositions for treatment of cancer
|
|
TW201106972A
(en)
|
2009-07-27 |
2011-03-01 |
Genentech Inc |
Combination treatments
|
|
ES2513292T3
(es)
|
2009-07-31 |
2014-10-24 |
Genentech, Inc. |
Inhibición de metástasis tumoral usando anticuerpos anti-G-CSF
|
|
MX355650B
(es)
|
2009-08-11 |
2018-04-26 |
Genentech Inc |
Produccion de proteinas en medios de cultivo de celulas libres de glutamina.
|
|
KR20120107069A
(ko)
|
2009-08-15 |
2012-09-28 |
제넨테크, 인크. |
이전에 치료된 유방암의 치료를 위한 항혈관신생 요법
|
|
BR112012004697B8
(pt)
|
2009-09-01 |
2021-05-25 |
Genentech Inc |
método para purificar um polipeptídeo compreendendo uma região ch2/ch3
|
|
RU2012114094A
(ru)
|
2009-09-11 |
2013-10-20 |
Дженентек, Инк. |
Способ идентификации пациента с увеличенной вероятностью ответа на противораковый агент
|
|
KR101557545B1
(ko)
|
2009-09-17 |
2015-10-06 |
에프. 호프만-라 로슈 아게 |
암 환자에서 진단 용도를 위한 방법 및 조성물
|
|
WO2011056502A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Bone morphogenetic protein receptor type ii compositions and methods of use
|
|
WO2011056497A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Activin receptor type iib compositions and methods of use
|
|
US8486397B2
(en)
|
2009-12-11 |
2013-07-16 |
Genentech, Inc. |
Anti-VEGF-C antibodies and methods using same
|
|
CN107095846A
(zh)
|
2009-12-21 |
2017-08-29 |
霍夫曼-拉罗奇有限公司 |
抗体配制剂
|
|
MX2012007379A
(es)
|
2009-12-23 |
2012-08-31 |
Genentech Inc |
Anticuerpos anti-bv8 y usos de los mismos.
|
|
WO2011095596A1
(en)
|
2010-02-04 |
2011-08-11 |
Vivalis |
Fed-batch process using concentrated cell culture medium for the efficient production of biologics in eb66 cells
|
|
SG10201401123VA
(en)
|
2010-02-23 |
2014-08-28 |
Genentech Inc |
Anti-Angiogenesis Therapy For The Treatment Of Ovarian Cancer
|
|
CA2791652C
(en)
|
2010-03-02 |
2018-06-12 |
Kyowa Kirin Co., Ltd. |
Modified antibody composition
|
|
KR101878369B1
(ko)
|
2010-03-22 |
2018-07-16 |
제넨테크, 인크. |
단백질-함유 제제의 안정화에 유용한 조성물 및 방법
|
|
EP2554669B1
(de)
|
2010-03-26 |
2018-09-19 |
Kyowa Hakko Kirin Co., Ltd. |
Neuer antikörper mit darin eingeführter modifikationsstelle und antikörperfragment
|
|
TWI510246B
(zh)
|
2010-04-30 |
2015-12-01 |
Molecular Partners Ag |
抑制vegf-a受體交互作用的經修飾結合性蛋白質
|
|
BR112012027828A2
(pt)
|
2010-05-03 |
2016-08-09 |
Genentech Inc |
composição de matéria, artigo de fabricação e método de redução da viscosidade de uma formulação contendo proteína e de preparação de uma formulação aquosa contendo proteína
|
|
CN102892791B
(zh)
|
2010-05-17 |
2017-05-17 |
Emd密理博公司 |
用于纯化生物分子的刺激响应性聚合物
|
|
JP6050226B2
(ja)
|
2010-05-28 |
2016-12-21 |
ジェネンテック, インコーポレイテッド |
Ldh及びpdhk発現を下方制御することによる乳酸レベルの低下及びポリペプチド生産の増加
|
|
WO2011153243A2
(en)
|
2010-06-02 |
2011-12-08 |
Genentech, Inc. |
Anti-angiogenesis therapy for treating gastric cancer
|
|
WO2011153224A2
(en)
|
2010-06-02 |
2011-12-08 |
Genentech, Inc. |
Diagnostic methods and compositions for treatment of cancer
|
|
KR101924653B1
(ko)
|
2010-06-24 |
2018-12-03 |
제넨테크, 인크. |
단백질-함유 제제를 안정화시키기 위한 알킬글리코시드 함유 조성물 및 방법
|
|
NZ605449A
(en)
|
2010-07-09 |
2015-03-27 |
Genentech Inc |
Anti-neuropilin antibodies and methods of use
|
|
WO2012010549A1
(en)
|
2010-07-19 |
2012-01-26 |
F. Hoffmann-La Roche Ag |
Method to identify a patient with an increased likelihood of responding to an anti-cancer therapy
|
|
CN104634971A
(zh)
|
2010-07-19 |
2015-05-20 |
霍夫曼-拉罗奇有限公司 |
鉴定响应抗癌疗法的可能性升高的患者的方法
|
|
WO2012017925A1
(ja)
|
2010-08-02 |
2012-02-09 |
協和発酵キリン株式会社 |
物質の製造方法
|
|
CN104474546A
(zh)
|
2010-08-13 |
2015-04-01 |
弗·哈夫曼-拉罗切有限公司 |
用于疾病治疗的针对IL-1β和IL-18的抗体
|
|
AR082693A1
(es)
|
2010-08-17 |
2012-12-26 |
Roche Glycart Ag |
Terapia de combinacion de un anticuerpo anti-cd20 afucosilado con un anticuerpo anti-vegf
|
|
WO2012030512A1
(en)
|
2010-09-03 |
2012-03-08 |
Percivia Llc. |
Flow-through protein purification process
|
|
MX349293B
(es)
|
2010-11-15 |
2017-07-21 |
Five Prime Therapeutics Inc * |
Tratamiento de cancer con dosis elevadas de proteinas de fusion del receptor del factor de crecimiento de fibroblastos 1 (fgfr1) solubles.
|
|
WO2012081628A1
(ja)
|
2010-12-15 |
2012-06-21 |
大学共同利用機関法人情報・システム研究機構 |
タンパク質の生産方法
|
|
US9611458B2
(en)
|
2010-12-27 |
2017-04-04 |
Kyowa Hakko Kirin Co., Ltd |
Method for preparing aqueous solution containing culture medium and chelating agent
|
|
WO2012092539A2
(en)
|
2010-12-31 |
2012-07-05 |
Takeda Pharmaceutical Company Limited |
Antibodies to dll4 and uses thereof
|
|
WO2012095514A1
(en)
|
2011-01-14 |
2012-07-19 |
Vivalis |
Recombinant protein production system
|
|
FI2694072T4
(fi)
|
2011-04-01 |
2024-09-30 |
Genentech Inc |
Akt-inhibiittoriyhdisteen ja abirateronin yhdistelmä käytettäväksi terapeuttisissa hoidoissa
|
|
US9527925B2
(en)
|
2011-04-01 |
2016-12-27 |
Boehringer Ingelheim International Gmbh |
Bispecific binding molecules binding to VEGF and ANG2
|
|
EP3549952A1
(de)
|
2011-04-20 |
2019-10-09 |
Acceleron Pharma Inc. |
Endoglinpolypeptide und verwendungen davon
|
|
WO2012151317A1
(en)
|
2011-05-03 |
2012-11-08 |
Genentech, Inc. |
Vascular disruption agents and uses thereof
|
|
WO2012172054A1
(en)
|
2011-06-16 |
2012-12-20 |
Scil Proteins Gmbh |
Modified multimeric ubiquitin proteins binding vegf-a
|
|
EP2551348B1
(de)
|
2011-07-29 |
2014-09-24 |
Icon Genetics GmbH |
Produktion von galactosylierten N-Glycanen in Pflanzen
|
|
JP2014525412A
(ja)
|
2011-08-17 |
2014-09-29 |
ジェネンテック, インコーポレイテッド |
難治性腫瘍における血管新生の阻害
|
|
US10196664B2
(en)
|
2011-10-04 |
2019-02-05 |
Icon Genetics Gmbh |
Nicotiana benthamiana plants deficient in fucosyltransferase activity
|
|
EP2785739B1
(de)
|
2011-12-01 |
2017-03-15 |
ThromboGenics N.V. |
Verbesserung eines augendrucksenkungsergebnisses
|
|
WO2013082511A1
(en)
|
2011-12-02 |
2013-06-06 |
Genentech, Inc. |
Methods for overcoming tumor resistance to vegf antagonists
|
|
PL2794635T3
(pl)
|
2011-12-22 |
2019-02-28 |
F.Hoffmann-La Roche Ag |
Membranowa chromatografia jonowymienna
|
|
PL2825558T3
(pl)
|
2012-03-13 |
2019-11-29 |
Hoffmann La Roche |
Terapia skojarzona w leczeniu raka jajnika
|
|
SG11201406112TA
(en)
|
2012-03-27 |
2014-10-30 |
Genentech Inc |
Improved harvest operations for recombinant proteins
|
|
ES2742379T3
(es)
|
2012-05-31 |
2020-02-14 |
Hoffmann La Roche |
Procedimientos de tratamiento del cáncer usando antagonistas de unión al eje de PD-1 y antagonistas de VEGF
|
|
SI3495387T1
(sl)
|
2012-07-13 |
2021-12-31 |
Roche Glycart Ag |
Bispecifična protitelesa proti VEGF/proti ANG-2 in njihova uporaba pri zdravljenju bolezni očesnih žil
|
|
EP3446709A1
(de)
|
2012-08-07 |
2019-02-27 |
F. Hoffmann-La Roche AG |
Kombinationstherapie zur behandlung von glioblastomen
|
|
US10035822B2
(en)
|
2012-11-15 |
2018-07-31 |
Apellis Pharmaceuticals, Inc. |
Cell-reactive, long-acting, or targeted compstatin analogs and related compositions and methods
|
|
WO2014100095A1
(en)
|
2012-12-19 |
2014-06-26 |
Genentech, Inc. |
Methods and compositions for radiohalogen protein labeling
|
|
MY170528A
(en)
|
2013-02-18 |
2019-08-09 |
Vegenics Pty Ltd |
Vegfr-3 ligand binding molecules and uses thereof
|
|
MX365567B
(es)
|
2013-03-13 |
2019-06-07 |
Genentech Inc |
Formulaciones de anticuerpo.
|
|
WO2014152391A1
(en)
|
2013-03-15 |
2014-09-25 |
Apellis Pharmaceuticals, Inc. |
Cell-penetrating compstatin analogs and uses thereof
|
|
WO2014190147A2
(en)
|
2013-05-23 |
2014-11-27 |
Five Prime Therapeutics, Inc. |
Methods of treating cancer
|
|
SI4374873T1
(sl)
|
2013-07-12 |
2026-01-30 |
Astellas Us Llc |
Sredstvo za uporabo pri zdravljenju ali preprečevanju oftalmoloških stanj
|
|
US10617755B2
(en)
|
2013-08-30 |
2020-04-14 |
Genentech, Inc. |
Combination therapy for the treatment of glioblastoma
|
|
US10456470B2
(en)
|
2013-08-30 |
2019-10-29 |
Genentech, Inc. |
Diagnostic methods and compositions for treatment of glioblastoma
|
|
AU2014339898B2
(en)
|
2013-10-25 |
2020-07-23 |
Acceleron Pharma, Inc. |
Endoglin peptides to treat fibrotic diseases
|
|
ES2875878T3
(es)
|
2013-11-18 |
2021-11-11 |
Formycon Ag |
Composición farmacéutica de un anticuerpo anti-VEGF
|
|
UA122479C2
(uk)
|
2014-01-24 |
2020-11-25 |
Дана-Фарбер Кенсер Інстітьют, Інк. |
Виділена молекула антитіла, яка зв’язується з людським білком програмованої смерті-1 (pd-1)
|
|
PL3099717T3
(pl)
|
2014-01-31 |
2019-10-31 |
Novartis Ag |
Cząsteczki przeciwciała dla TIM-3 i ich zastosowanie
|
|
EA201691765A1
(ru)
|
2014-03-14 |
2016-12-30 |
Новартис Аг |
Молекулы антител против lag-3 и их применения
|
|
EP3122900A1
(de)
|
2014-03-24 |
2017-02-01 |
F. Hoffmann-La Roche AG |
Krebsbehandlung mit c-met-antagonisten und korrelation desselben mit hgf-expression
|
|
KR20160146747A
(ko)
|
2014-03-31 |
2016-12-21 |
제넨테크, 인크. |
항혈관신생제 및 ox40 결합 효능제를 포함하는 조합 요법
|
|
WO2015173260A1
(en)
|
2014-05-12 |
2015-11-19 |
Formycon Ag |
Pre-filled plastic syringe containing a vegf antagonist
|
|
CN106686977B
(zh)
|
2014-07-09 |
2022-03-25 |
豪夫迈·罗氏有限公司 |
Ph调整以改善细胞库的解冻复苏
|
|
JP2017523776A
(ja)
|
2014-07-14 |
2017-08-24 |
ジェネンテック, インコーポレイテッド |
膠芽腫の診断方法及びその治療用組成物
|
|
EP3180018B1
(de)
|
2014-08-12 |
2019-07-24 |
Massachusetts Institute Of Technology |
Synergistische tumorbehandlung mit il-2 und integrin-bindendem fc-fusionsprotein
|
|
WO2016025647A1
(en)
|
2014-08-12 |
2016-02-18 |
Massachusetts Institute Of Technology |
Synergistic tumor treatment with il-2, a therapeutic antibody, and a cancer vaccine
|
|
WO2016029191A2
(en)
|
2014-08-22 |
2016-02-25 |
Auckland Uniservices Limited |
Channel modulators
|
|
EP3191126B1
(de)
|
2014-09-13 |
2020-05-13 |
Novartis AG |
Kombinationstherapien aus alk-hemmern
|
|
ES2949173T3
(es)
|
2014-09-15 |
2023-09-26 |
Hoffmann La Roche |
Formulaciones de anticuerpo
|
|
KR20170066546A
(ko)
|
2014-10-03 |
2017-06-14 |
노파르티스 아게 |
조합 요법
|
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
|
SG11201702401RA
(en)
|
2014-10-14 |
2017-04-27 |
Novartis Ag |
Antibody molecules to pd-l1 and uses thereof
|
|
JP6929771B2
(ja)
|
2014-11-10 |
2021-09-01 |
ジェネンテック, インコーポレイテッド |
抗インターロイキン−33抗体及びその使用
|
|
EP3233918A1
(de)
|
2014-12-19 |
2017-10-25 |
Novartis AG |
Kombinationstherapien
|
|
EP3237639A2
(de)
|
2014-12-23 |
2017-11-01 |
Genentech, Inc. |
Zusammensetzungen und verfahren zur behandlung und diagnostizierung von chemotherapieresistentem krebs
|
|
EP3303397A1
(de)
|
2015-06-08 |
2018-04-11 |
H. Hoffnabb-La Roche Ag |
Verfahren zur krebsbehandlung mit anti-ox40-antikörpern und pd-1-achsen-bindungsantagonisten
|
|
US20180340025A1
(en)
|
2015-07-29 |
2018-11-29 |
Novartis Ag |
Combination therapies comprising antibody molecules to lag-3
|
|
EP3328418A1
(de)
|
2015-07-29 |
2018-06-06 |
Novartis AG |
Kombinationstherapien mit antikörpermolekülen gegen pd-1
|
|
US20180207273A1
(en)
|
2015-07-29 |
2018-07-26 |
Novartis Ag |
Combination therapies comprising antibody molecules to tim-3
|
|
KR20180090785A
(ko)
|
2015-10-07 |
2018-08-13 |
아펠리스 파마슈티컬스 인코포레이티드 |
투여 요법
|
|
BR112018007703A2
(pt)
|
2015-10-30 |
2018-11-06 |
Genentech Inc |
anticorpos, ácido nucleico isolado, métodos de produção de um anticorpo e de tratamento de um distúrbio, composição farmacêutica, terapia de combinação e uso do anticorpo
|
|
PT3370768T
(pt)
|
2015-11-03 |
2022-04-21 |
Janssen Biotech Inc |
Anticorpos que se ligam especificamente ao pd-1 e seus usos
|
|
KR102854749B1
(ko)
|
2015-11-18 |
2025-09-04 |
에스아이오2 메디컬 프로덕츠, 엘엘씨 |
안과 제제용 제약 패키지
|
|
CN108883172A
(zh)
|
2015-11-18 |
2018-11-23 |
福迈康股份公司 |
包含vegf拮抗剂的液体配制品的预填充药物包装
|
|
US20180326126A1
(en)
|
2015-11-18 |
2018-11-15 |
Formycon Ag |
Pre-filled plastic syringe containing a vegf antagonist
|
|
CN108495651A
(zh)
|
2015-12-17 |
2018-09-04 |
诺华股份有限公司 |
抗pd-1的抗体分子及其用途
|
|
EP3407868A1
(de)
|
2016-01-26 |
2018-12-05 |
Formycon AG |
Flüssigformulierung eines vegf-antagonisten
|
|
JP2019510517A
(ja)
|
2016-03-29 |
2019-04-18 |
ジェルター, インコーポレイテッド |
細胞質内体積に対するペリプラズム体積の比率が0.5:1および10:1の間にあるグラム陰性細菌におけるタンパク質の発現
|
|
PL3443350T3
(pl)
|
2016-04-15 |
2021-05-31 |
F. Hoffmann-La Roche Ag |
Sposoby monitorowania i leczenia nowotworu
|
|
WO2017181079A2
(en)
|
2016-04-15 |
2017-10-19 |
Genentech, Inc. |
Methods for monitoring and treating cancer
|
|
JP2019524706A
(ja)
|
2016-07-08 |
2019-09-05 |
ジェネンテック, インコーポレイテッド |
Muc16陽性癌治療の応答性を評価するためのヒト精巣上体タンパク質4(he4)の使用
|
|
EP3481963B1
(de)
|
2016-07-08 |
2025-10-29 |
Genentech, Inc. |
Methoden zur diagnose und behandlung von krebs durch bestimmung des expressionsstatus und mutatonsstatus von nrf2 sowie downstream genen von nrf2.
|
|
CN109689102A
(zh)
|
2016-08-12 |
2019-04-26 |
基因泰克公司 |
Mek抑制剂,pd-1轴抑制剂,和vegf抑制剂的组合疗法
|
|
US10350266B2
(en)
|
2017-01-10 |
2019-07-16 |
Nodus Therapeutics, Inc. |
Method of treating cancer with a multiple integrin binding Fc fusion protein
|
|
EP3568150A4
(de)
|
2017-01-10 |
2020-12-02 |
Xcella Biosciences, Inc. |
Kombinationstumorbehandlung mit integrin-bindendem fc-fusionsprotein und immunmodulator
|
|
MX2019010295A
(es)
|
2017-03-01 |
2019-11-21 |
Genentech Inc |
Métodos de diagnóstico y terapéuticos para el cáncer.
|
|
BR112019020955A2
(pt)
|
2017-04-07 |
2020-05-05 |
Apellis Pharmaceuticals, Inc. |
regimes de dosagem e composições e métodos relacionados
|
|
WO2018215580A1
(en)
|
2017-05-24 |
2018-11-29 |
Formycon Ag |
Method for sterilizing prefilled plastic syringes containing a vegf antagonist
|
|
US20200171244A1
(en)
|
2017-05-24 |
2020-06-04 |
Sio2 Medical Products, Inc. |
Sterilizable pharmaceutical package for ophthalmic formulations
|
|
WO2018217995A1
(en)
|
2017-05-24 |
2018-11-29 |
Formycon Ag |
Sterilizable pre-filled pharmaceutical packages comprising a liquid formulation of a vegf-antagonist
|
|
MX2019015885A
(es)
|
2017-06-22 |
2020-09-10 |
Novartis Ag |
Moleculas de anticuerpo que se unen a cd73 y usos de las mismas.
|
|
US20200172628A1
(en)
|
2017-06-22 |
2020-06-04 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
WO2019020777A1
(en)
|
2017-07-26 |
2019-01-31 |
Formycon Ag |
LIQUID FORMULATION OF A VEGF ANTAGONIST
|
|
US11180541B2
(en)
|
2017-09-28 |
2021-11-23 |
Geltor, Inc. |
Recombinant collagen and elastin molecules and uses thereof
|
|
JP2021507884A
(ja)
|
2017-12-15 |
2021-02-25 |
アペリス・ファーマシューティカルズ・インコーポレイテッドApellis Pharmaceuticals,Inc. |
投与レジメンならびに関連組成物および方法
|
|
US12398209B2
(en)
|
2018-01-22 |
2025-08-26 |
Janssen Biotech, Inc. |
Methods of treating cancers with antagonistic anti-PD-1 antibodies
|
|
CN111699004A
(zh)
|
2018-02-06 |
2020-09-22 |
豪夫迈·罗氏有限公司 |
眼科疾病的治疗
|
|
CN113975264A
(zh)
|
2018-04-16 |
2022-01-28 |
上海岸阔医药科技有限公司 |
预防或治疗肿瘤疗法副作用的方法
|
|
MX2020012598A
(es)
|
2018-05-24 |
2021-05-27 |
Janssen Biotech Inc |
Agentes aglutinantes del psma y usos de estos.
|
|
UY38247A
(es)
|
2018-05-30 |
2019-12-31 |
Novartis Ag |
Anticuerpos frente a entpd2, terapias de combinación y métodos de uso de los anticuerpos y las terapias de combinación
|
|
WO2019232244A2
(en)
|
2018-05-31 |
2019-12-05 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
IL279782B2
(en)
|
2018-07-03 |
2026-05-01 |
Bristol Myers Squibb Co |
Methods for producing recombinant proteins
|
|
KR20210074341A
(ko)
|
2018-10-10 |
2021-06-21 |
베링거 인겔하임 인터내셔날 게엠베하 |
고밀도 생물 반응기 배양에서 막 기체 전달을 위한 방법
|
|
EP3867646A1
(de)
|
2018-10-18 |
2021-08-25 |
F. Hoffmann-La Roche AG |
Diagnostische und therapeutische verfahren für sarkomatoiden nierenkrebs
|
|
EP3875595A4
(de)
|
2018-11-02 |
2022-07-13 |
Kyowa Kirin Co., Ltd. |
Verfahren zur herstellung eines flüssigen mediums
|
|
WO2020109343A1
(en)
|
2018-11-29 |
2020-06-04 |
F. Hoffmann-La Roche Ag |
Combination therapy for treatment of macular degeneration
|
|
WO2020205716A1
(en)
|
2019-04-01 |
2020-10-08 |
Genentech, Inc. |
Compositions and methods for stabilizing protein-containing formulations
|
|
GB2597416A
(en)
|
2019-04-12 |
2022-01-26 |
Geltor Inc |
Recombinant elastin and production thereof
|
|
AR118720A1
(es)
|
2019-04-19 |
2021-10-27 |
Janssen Biotech Inc |
Métodos para tratar el cáncer de próstata con un anticuerpo anti-psma / cd3
|
|
MX2021013222A
(es)
|
2019-05-03 |
2022-01-06 |
Genentech Inc |
Metodos para tratar el cancer con un anticuerpo anti-pd-l1.
|
|
PE20240329A1
(es)
|
2019-06-05 |
2024-02-27 |
Regeneron Pharma |
Dispositivos y metodos para administracion de dosis de precision
|
|
US20220315887A1
(en)
|
2019-08-01 |
2022-10-06 |
Bristol-Myers Squibb Company |
Methods of improving protein productivity in fed-batch cell cultures
|
|
JP2022548881A
(ja)
|
2019-09-18 |
2022-11-22 |
ノバルティス アーゲー |
Entpd2抗体、組合せ療法並びに抗体及び組合せ療法を使用する方法
|
|
US12385054B2
(en)
|
2019-11-19 |
2025-08-12 |
Protalix Ltd. |
Removal of constructs from transformed cells
|
|
EP4118114A1
(de)
|
2020-03-13 |
2023-01-18 |
Genentech, Inc. |
Anti-interleukin-33-antikörper und verwendungen davon
|
|
US12091681B2
(en)
|
2020-03-27 |
2024-09-17 |
Mendus B.V. |
Ex vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy
|
|
CN115698717A
(zh)
|
2020-04-03 |
2023-02-03 |
基因泰克公司 |
癌症的治疗和诊断方法
|
|
WO2022003568A1
(en)
|
2020-06-30 |
2022-01-06 |
Dcprime B.V. |
Use of leukemia-derived cells in ovarian cancer vaccines
|
|
CN116194570A
(zh)
|
2020-09-22 |
2023-05-30 |
百时美施贵宝公司 |
用于产生治疗性蛋白的方法
|
|
JP2023545999A
(ja)
|
2020-10-05 |
2023-11-01 |
プロタリクス リミテッド |
ダイサー(dicer)様ノックアウト植物細胞
|
|
KR102975432B1
(ko)
|
2020-11-13 |
2026-06-10 |
제넨테크, 인크. |
고형 종양 치료를 위한 krasg12c 억제제 및 vegf 억제제를 포함하는 방법 및 조성물
|
|
KR20230135075A
(ko)
|
2021-01-22 |
2023-09-22 |
멘두스 비.브이. |
종양 백신접종 방법
|
|
MX2023008909A
(es)
|
2021-01-28 |
2023-10-23 |
Janssen Biotech Inc |
Proteínas de unión a psma y usos de estas.
|
|
WO2022190058A1
(en)
|
2021-03-12 |
2022-09-15 |
Dcprime B.V. |
Methods of vaccination and use of cd47 blockade
|
|
EP4329734A4
(de)
|
2021-04-26 |
2025-04-02 |
Celanese EVA Performance Polymers LLC |
Implantierbare vorrichtung zur verzögerten freisetzung einer makromolekularen arzneimittelverbindung
|
|
JP2024516230A
(ja)
|
2021-04-30 |
2024-04-12 |
ジェネンテック, インコーポレイテッド |
がんのための治療及び診断方法並びに組成物
|
|
KR20240028452A
(ko)
|
2021-07-02 |
2024-03-05 |
제넨테크, 인크. |
암을 치료하기 위한 방법 및 조성물
|
|
IL309120A
(en)
|
2021-07-28 |
2024-02-01 |
Hoffmann La Roche |
Methods and compositions for the treatment of cancer
|
|
US20250115666A1
(en)
|
2021-08-05 |
2025-04-10 |
Bristol-Myers Squibb Company |
Cell culture methods for producing therapeutic proteins
|
|
US12649031B2
(en)
|
2021-09-08 |
2026-06-09 |
Regeneron Pharmaceuticals, Inc. |
Methods for delivering agents with pre-filled syringes to minimize intraocular inflammation
|
|
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|
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|
|
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|
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|
|
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|
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|
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|
|
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|
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|
|
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|
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|
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|
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