|
US6168778B1
(en)
|
1990-06-11 |
2001-01-02 |
Nexstar Pharmaceuticals, Inc. |
Vascular endothelial growth factor (VEGF) Nucleic Acid Ligand Complexes
|
|
US6762290B1
(en)
|
1999-07-29 |
2004-07-13 |
Gilead Sciences, Inc. |
High affinity vascular endothelial growth factor (VEGF) receptor nucleic acid ligands and inhibitors
|
|
US6818220B1
(en)
|
1994-11-14 |
2004-11-16 |
Licentia Ltd. |
Vascular endothelial growth factor C (VEGF-C) protein and gene mutants thereof, and uses thereof
|
|
US6403088B1
(en)
|
1995-08-01 |
2002-06-11 |
Helsinki University Licensing, Ltd. |
Antibodies reactive with VEGF-C, a ligand for the Flt4 receptor tyrosine kinase (VEGFR-3)
|
|
US6645933B1
(en)
|
1995-08-01 |
2003-11-11 |
Helsinki University Licensing Ltd. Oy |
Receptor ligand VEGF-C
|
|
US6130071A
(en)
*
|
1997-02-05 |
2000-10-10 |
Helsinki University Licensing, Ltd. |
Vascular endothelial growth factor C (VEGF-C) ΔCys156 protein and gene, and uses thereof
|
|
US6221839B1
(en)
|
1994-11-14 |
2001-04-24 |
Helsinki University Licensing Ltd. Oy |
FIt4 ligand and methods of use
|
|
US6245530B1
(en)
|
1995-08-01 |
2001-06-12 |
Ludwig Institute For Cancer Research |
Receptor ligand
|
|
US6685940B2
(en)
|
1995-07-27 |
2004-02-03 |
Genentech, Inc. |
Protein formulation
|
|
US6267958B1
(en)
|
1995-07-27 |
2001-07-31 |
Genentech, Inc. |
Protein formulation
|
|
US6361946B1
(en)
|
1997-02-05 |
2002-03-26 |
Licentia Ltd |
Vascular endothelial growth factor C (VEGF-C) protein and gene, mutants thereof, and uses thereof
|
|
US7423125B2
(en)
|
1995-08-01 |
2008-09-09 |
Vegenics Limited |
Antibodies to VEGF-C
|
|
US7371376B1
(en)
|
1996-10-18 |
2008-05-13 |
Genentech, Inc. |
Anti-ErbB2 antibodies
|
|
US6426335B1
(en)
|
1997-10-17 |
2002-07-30 |
Gilead Sciences, Inc. |
Vascular endothelial growth factor (VEGF) nucleic acid ligand complexes
|
|
US6051698A
(en)
*
|
1997-06-06 |
2000-04-18 |
Janjic; Nebojsa |
Vascular endothelial growth factor (VEGF) nucleic acid ligand complexes
|
|
US7125714B2
(en)
|
1997-02-05 |
2006-10-24 |
Licentia Ltd. |
Progenitor cell materials and methods
|
|
IL132240A0
(en)
|
1997-04-07 |
2001-03-19 |
Genentech Inc |
Anti-vegf antibodies
|
|
US6884879B1
(en)
|
1997-04-07 |
2005-04-26 |
Genentech, Inc. |
Anti-VEGF antibodies
|
|
US20070059302A1
(en)
|
1997-04-07 |
2007-03-15 |
Genentech, Inc. |
Anti-vegf antibodies
|
|
US20020032315A1
(en)
|
1997-08-06 |
2002-03-14 |
Manuel Baca |
Anti-vegf antibodies
|
|
DE19744531A1
(de)
*
|
1997-10-09 |
1999-05-27 |
Klaus Dr Rer Nat Bosslet |
Bindemoleküle gegen Rezeptor-Ligand-Komplexe
|
|
US6391311B1
(en)
|
1998-03-17 |
2002-05-21 |
Genentech, Inc. |
Polypeptides having homology to vascular endothelial cell growth factor and bone morphogenetic protein 1
|
|
GB9723780D0
(en)
*
|
1997-11-12 |
1998-01-07 |
Univ Manchester |
Regulation of ocular angiogenesis
|
|
IL137649A
(en)
*
|
1998-02-18 |
2004-08-31 |
Genentech Inc |
Method of adsorption chromatography
|
|
ES2389387T3
(es)
|
1998-03-17 |
2012-10-25 |
Genentech, Inc. |
Polipéptidos homólogos de VEGF y de BMP1
|
|
EP2016953A3
(de)
|
1998-12-22 |
2009-04-15 |
Genentech, Inc. |
Vaskuläre endotheliale Zellwachstumsfaktor-Antagonisten und Verwendungen
|
|
DE10008946C1
(de)
|
2000-02-25 |
2001-10-18 |
Basf Coatings Ag |
Verfahren zur Herstellung farb- und/oder effektgebender Mehrschichtlackierungen auf Automobilkarosserien
|
|
EP2042597B1
(de)
|
2000-06-23 |
2014-05-07 |
Genentech, Inc. |
Zusammensetzungen und Verfahren zur Diagnose und Behandlung von Erkrankungen in Verbindung mit Angiogenese
|
|
CA2709771A1
(en)
|
2000-06-23 |
2002-01-03 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
|
|
DE10043405C1
(de)
|
2000-09-04 |
2002-06-27 |
Basf Coatings Ag |
Verfahren zur Herstellung farb- und/oder effektgebender Lackierungen
|
|
DE10130972C1
(de)
|
2001-06-27 |
2002-11-07 |
Basf Coatings Ag |
Verfahren zur Herstellung von Beschichtungen aus thermisch und mit aktinischer Strahlung härtbaren Beschichtungsstoffen und mit dem Verfahren herstellbare Lackierungen
|
|
US20050123925A1
(en)
|
2002-11-15 |
2005-06-09 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
CA2473144C
(en)
|
2002-02-05 |
2013-05-28 |
Genentech, Inc. |
Protein purification
|
|
US20050106136A1
(en)
*
|
2002-02-15 |
2005-05-19 |
Richard Brunner |
7s immunoglobulin for treatment of choroidal neovascularisation
|
|
DK1501369T3
(en)
|
2002-04-26 |
2015-09-28 |
Genentech Inc |
Non-affinity purification of proteins
|
|
NZ621449A
(en)
*
|
2003-05-30 |
2015-07-31 |
Genentech Inc |
Treatment with anti-vegf antibodies
|
|
US7601341B2
(en)
|
2003-06-05 |
2009-10-13 |
Research Development Foundation |
Vascular endothelial growth factor fusion constructs used to inhibit osteoclastogenesis
|
|
HUE029951T2
(en)
|
2003-07-28 |
2017-04-28 |
Genentech Inc |
Reduction of Protein A Dissolution in Protein A Affinity Chromatography
|
|
NZ592039A
(en)
|
2003-08-27 |
2013-03-28 |
Ophthotech Corp |
Combination therapy for the treatment of ocular neovascular disorders
|
|
DE102004027650A1
(de)
|
2004-06-05 |
2006-01-05 |
Basf Coatings Ag |
Verfahren zum Beschichten elektrisch leitfähiger Substrate
|
|
US8604185B2
(en)
|
2004-07-20 |
2013-12-10 |
Genentech, Inc. |
Inhibitors of angiopoietin-like 4 protein, combinations, and their use
|
|
EP1771474B1
(de)
|
2004-07-20 |
2010-01-27 |
Genentech, Inc. |
Angiopoietin-like 4 protein hemmer kombinationen und deren verwendung
|
|
US7662926B2
(en)
|
2004-09-02 |
2010-02-16 |
Genentech, Inc. |
Anti-Fc-gamma receptor antibodies, bispecific variants and uses therefor
|
|
US7655229B2
(en)
|
2004-09-02 |
2010-02-02 |
Chan Andrew C |
Anti-FC-gamma RIIB receptor antibody and uses therefor
|
|
EP1802334B1
(de)
*
|
2004-10-21 |
2012-08-29 |
Genentech, Inc. |
Methode zur behandlung von intraokulären neovaskularisations erkrankungen
|
|
MX2007011735A
(es)
|
2005-03-24 |
2008-03-14 |
Thrombogenics Nv |
Anticuerpo anti-plgf novedoso.
|
|
US20070025957A1
(en)
*
|
2005-04-29 |
2007-02-01 |
Rosenblum Michael G |
Vascular targeting of ocular neovascularization
|
|
US7867490B2
(en)
|
2005-06-30 |
2011-01-11 |
Vib Vzw |
Treatment of liver cirrhosis and its complications
|
|
WO2007011873A2
(en)
*
|
2005-07-15 |
2007-01-25 |
Genentech, Inc. |
Method for treating intraocular neovascular diseases
|
|
US8168584B2
(en)
*
|
2005-10-08 |
2012-05-01 |
Potentia Pharmaceuticals, Inc. |
Methods of treating age-related macular degeneration by compstatin and analogs thereof
|
|
UA96139C2
(uk)
|
2005-11-08 |
2011-10-10 |
Дженентек, Інк. |
Антитіло до нейропіліну-1 (nrp1)
|
|
EP1973950B1
(de)
|
2006-01-05 |
2014-09-17 |
Genentech, Inc. |
Anti-ephb4-antikörper sowie verfahren zu deren verwendung
|
|
CN103193885B
(zh)
|
2006-01-20 |
2015-05-13 |
健泰科生物技术公司 |
抗ephrinb2抗体及其使用方法
|
|
AR059851A1
(es)
|
2006-03-16 |
2008-04-30 |
Genentech Inc |
Anticuerpos de la egfl7 y metodos de uso
|
|
AR061246A1
(es)
|
2006-06-06 |
2008-08-13 |
Genentech Inc |
Anticuerpos anti- dill4 y metodos que los usan
|
|
FR2902799B1
(fr)
|
2006-06-27 |
2012-10-26 |
Millipore Corp |
Procede et unite de preparation d'un echantillon pour l'analyse microbiologique d'un liquide
|
|
JP5960944B2
(ja)
|
2006-11-15 |
2016-08-02 |
コーダ セラピューティクス, インコーポレイテッド |
創傷治癒のための改善された方法および組成物
|
|
MY183404A
(en)
|
2006-12-19 |
2021-02-18 |
Genentech Inc |
Vegf-specific antagonists for adjuvant and neoadjuvant therapy and the treatment of early stage tumors
|
|
US8569464B2
(en)
|
2006-12-21 |
2013-10-29 |
Emd Millipore Corporation |
Purification of proteins
|
|
WO2008079280A1
(en)
|
2006-12-21 |
2008-07-03 |
Millipore Corporation |
Purification of proteins
|
|
US8362217B2
(en)
|
2006-12-21 |
2013-01-29 |
Emd Millipore Corporation |
Purification of proteins
|
|
JP5361738B2
(ja)
|
2007-01-22 |
2013-12-04 |
ジェネンテック, インコーポレイテッド |
多価電解質沈殿物及びタンパク質の精製
|
|
WO2008143666A2
(en)
|
2007-05-17 |
2008-11-27 |
Genentech, Inc. |
Crystal structures of neuropilin fragments and neuropilin-antibody complexes
|
|
US8648173B2
(en)
|
2007-05-17 |
2014-02-11 |
Genentech, Inc. |
Inhibition of tumor metastasis by anti neuropilin 2 antibodies
|
|
PE20090321A1
(es)
|
2007-06-04 |
2009-04-20 |
Genentech Inc |
Anticuerpos anti-notch1 nrr, metodo de preparacion y composicion farmaceutica
|
|
HUE037162T2
(hu)
|
2007-07-09 |
2018-08-28 |
Genentech Inc |
Diszulfidkötés redukciójának megelõzése polipeptidek rekombináns elõállítása során
|
|
CN105315323A
(zh)
|
2007-10-30 |
2016-02-10 |
健泰科生物技术公司 |
通过阳离子交换层析进行的抗体纯化
|
|
ES2554812T3
(es)
|
2007-11-09 |
2015-12-23 |
Genentech, Inc. |
Composiciones de antagonistas de quinasa 1 de tipo receptor de activina y métodos de uso
|
|
TWI580694B
(zh)
|
2007-11-30 |
2017-05-01 |
建南德克公司 |
抗-vegf抗體
|
|
WO2009151514A1
(en)
|
2008-06-11 |
2009-12-17 |
Millipore Corporation |
Stirred tank bioreactor
|
|
HRP20241467T1
(hr)
|
2008-06-25 |
2025-01-03 |
Novartis Ag |
Stabilna i topljiva protutijela koja inhibiraju vegf
|
|
ES2978373T3
(es)
|
2008-08-14 |
2024-09-11 |
Genentech Inc |
Métodos para eliminar un contaminante usando cromatografía de membrana de intercambio iónico de desplazamiento de proteínas indígenas
|
|
MX2011002372A
(es)
|
2008-09-10 |
2011-04-04 |
Genentech Inc |
Composiciones y metodos para la prevencion de la degradacion oxidativa de proteinas.
|
|
CN102239178B
(zh)
|
2008-10-02 |
2017-06-23 |
Vib研究所 |
抑制PlGF以治疗费城染色体阳性白血病
|
|
KR101834999B1
(ko)
|
2008-10-14 |
2018-03-06 |
제넨테크, 인크. |
이뮤노글로불린 변이체 및 그의 용도
|
|
MX359570B
(es)
|
2008-11-03 |
2018-10-01 |
Molecular Partners Ag |
Proteinas de union que inhiben la interaccion en el receptor de vegf-a.
|
|
PL2752189T3
(pl)
|
2008-11-22 |
2017-04-28 |
F. Hoffmann-La Roche Ag |
Zastosowanie przeciwciała anty-VEGF w połączeniu z chemioterapią do leczenia raka sutka
|
|
SG171764A1
(en)
|
2008-12-16 |
2011-07-28 |
Millipore Corp |
Purification of proteins
|
|
US20100190963A1
(en)
|
2008-12-16 |
2010-07-29 |
Millipore Corporation |
Stirred Tank Reactor And Method
|
|
SG172355A1
(en)
|
2008-12-23 |
2011-07-28 |
Genentech Inc |
Methods and compositions for diagnostic use in cancer patients
|
|
SG173812A1
(en)
|
2009-02-27 |
2011-09-29 |
Genentech Inc |
Methods and compositions for protein labelling
|
|
SG175891A1
(en)
|
2009-05-08 |
2011-12-29 |
Genentech Inc |
Humanized anti-egfl7 antibodies and methods using same
|
|
AU2010262087B9
(en)
|
2009-06-15 |
2015-07-30 |
Icon Genetics Gmbh |
Nicotiana benthamiana plants deficient in xylosyltransferase activity
|
|
SG10201510152RA
(en)
|
2009-07-13 |
2016-01-28 |
Genentech Inc |
Diagnostic methods and compositions for treatment of cancer
|
|
TW201106972A
(en)
|
2009-07-27 |
2011-03-01 |
Genentech Inc |
Combination treatments
|
|
KR20120089253A
(ko)
|
2009-07-31 |
2012-08-09 |
제넨테크, 인크. |
Bv8? 또는 g?csf?길항제를 이용한 종양 전이의 억제
|
|
WO2011019619A1
(en)
|
2009-08-11 |
2011-02-17 |
Genentech, Inc. |
Production of proteins in glutamine-free cell culture media
|
|
MX336476B
(es)
|
2009-08-15 |
2016-01-20 |
Genentech Inc |
Terapia anti-angiogenesis para el tratamiento de cancer de mama previamente tratado.
|
|
EP3736338A1
(de)
|
2009-09-01 |
2020-11-11 |
F. Hoffmann-La Roche AG |
Verbesserte proteinreinigung durch eine modifizierte protein-a-elution
|
|
SG179070A1
(en)
|
2009-09-11 |
2012-04-27 |
Genentech Inc |
Method to identify a patient with an increased likelihood of responding to an anti-cancer agent
|
|
MX2012002909A
(es)
|
2009-09-17 |
2012-04-19 |
Hoffmann La Roche |
Metodos y composiciones para su uso en diagnostico de pacientes con cancer.
|
|
WO2011056497A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Activin receptor type iib compositions and methods of use
|
|
WO2011056502A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Bone morphogenetic protein receptor type ii compositions and methods of use
|
|
TWI505836B
(zh)
|
2009-12-11 |
2015-11-01 |
Genentech Inc |
抗-vegf-c抗體及其使用方法
|
|
BR112012013093A2
(pt)
|
2009-12-21 |
2017-12-12 |
Genentech Inc |
''formulação farmacêutica aquosa estável, artigo, métodos para estabilizar um anticorpo, para tratamento de uma doença ou distúrbio em um indivíduo, para reduzir a agregação de um anticorpo monoclonal terapêutico e de fabricação de uma formulação farmaceutica, frasco e tanque de aço inoxidável
|
|
NZ600826A
(en)
|
2009-12-23 |
2014-09-26 |
Genentech Inc |
Anti-bv8 antibodies and uses thereof
|
|
EP2531592A1
(de)
|
2010-02-04 |
2012-12-12 |
Vivalis |
Fed-batch-verfahren mit konzentriertem zellkulturmedium zur effizienten produktion von biologischen wirkstoffen bei eb66-zellen
|
|
TWI619509B
(zh)
|
2010-02-23 |
2018-04-01 |
建南德克公司 |
治療先前未經治療之ⅲ期或ⅳ期卵巢癌、輸卵管癌或原發性腹膜癌之卡鉑、太平洋紫杉醇與抗-vegf抗體之組合
|
|
EP2543727B1
(de)
|
2010-03-02 |
2016-08-31 |
Kyowa Hakko Kirin Co., Ltd. |
Modifizierte antikörperzusammensetzung
|
|
CA2792125C
(en)
|
2010-03-22 |
2019-02-12 |
Genentech, Inc. |
Compositions and methods useful for stabilizing protein-containing formulations
|
|
WO2011118739A1
(ja)
|
2010-03-26 |
2011-09-29 |
協和発酵キリン株式会社 |
新規修飾部位導入抗体および抗体フラグメント
|
|
AR081361A1
(es)
|
2010-04-30 |
2012-08-29 |
Molecular Partners Ag |
Proteinas de union modificadas que inhiben la interaccion de receptor del factor de crecimiento endotelial vascular de glicoproteina a vegf-a
|
|
CN102958538A
(zh)
|
2010-05-03 |
2013-03-06 |
弗·哈夫曼-拉罗切有限公司 |
用于降低含有蛋白质的制剂的粘度的组合物和方法
|
|
EP2571903B1
(de)
|
2010-05-17 |
2019-09-04 |
EMD Millipore Corporation |
Stimulusreaktive polymere zur aufreinigung von biomolekülen
|
|
WO2011150241A2
(en)
|
2010-05-28 |
2011-12-01 |
Genentech, Inc. |
Decreasing lactate level and increasing polypeptide production by downregulating the expression of lactate dehydrogenase and pyruvate dehydrogenase kinase
|
|
WO2011153243A2
(en)
|
2010-06-02 |
2011-12-08 |
Genentech, Inc. |
Anti-angiogenesis therapy for treating gastric cancer
|
|
WO2011153224A2
(en)
|
2010-06-02 |
2011-12-08 |
Genentech, Inc. |
Diagnostic methods and compositions for treatment of cancer
|
|
MY184736A
(en)
|
2010-06-24 |
2021-04-20 |
Genentech Inc |
Compositions and methods containing alkylglycosides for stabilizing protein-containing formulations
|
|
WO2012006503A1
(en)
|
2010-07-09 |
2012-01-12 |
Genentech, Inc. |
Anti-neuropilin antibodies and methods of use
|
|
CN103109189A
(zh)
|
2010-07-19 |
2013-05-15 |
霍夫曼-拉罗奇有限公司 |
鉴定响应抗癌疗法的可能性升高的患者的方法
|
|
EP2596359A1
(de)
|
2010-07-19 |
2013-05-29 |
F.Hoffmann-La Roche Ag |
Verfahren zur identifizierung eines patienten mit erhöhter wahrscheinlichkeit des ansprechens auf eine antitumortherapie
|
|
WO2012017925A1
(ja)
|
2010-08-02 |
2012-02-09 |
協和発酵キリン株式会社 |
物質の製造方法
|
|
CN104474546A
(zh)
|
2010-08-13 |
2015-04-01 |
弗·哈夫曼-拉罗切有限公司 |
用于疾病治疗的针对IL-1β和IL-18的抗体
|
|
AR082693A1
(es)
|
2010-08-17 |
2012-12-26 |
Roche Glycart Ag |
Terapia de combinacion de un anticuerpo anti-cd20 afucosilado con un anticuerpo anti-vegf
|
|
WO2012030512A1
(en)
|
2010-09-03 |
2012-03-08 |
Percivia Llc. |
Flow-through protein purification process
|
|
BR112013012041A2
(pt)
|
2010-11-15 |
2016-11-08 |
Five Prime Therapeutics Inc |
''terapias de combinações de domínio extracelular fgfr1"
|
|
PT2653540T
(pt)
|
2010-12-15 |
2018-02-27 |
Kyowa Hakko Kirin Co Ltd |
Processo de produção de proteínas
|
|
EP3147355B1
(de)
|
2010-12-27 |
2020-07-22 |
Kyowa Kirin Co., Ltd. |
Verfahren zur herstellung einer wässrigen lösung mit einem kulturmedium und einem chelatbildner
|
|
WO2012092539A2
(en)
|
2010-12-31 |
2012-07-05 |
Takeda Pharmaceutical Company Limited |
Antibodies to dll4 and uses thereof
|
|
WO2012095514A1
(en)
|
2011-01-14 |
2012-07-19 |
Vivalis |
Recombinant protein production system
|
|
US9527925B2
(en)
|
2011-04-01 |
2016-12-27 |
Boehringer Ingelheim International Gmbh |
Bispecific binding molecules binding to VEGF and ANG2
|
|
ES2620644T3
(es)
|
2011-04-01 |
2017-06-29 |
Genentech, Inc. |
Combinaciones de compuestos inhibidores de AKT y agentes quimioterapéuticos, y métodos de uso
|
|
CN108178789B
(zh)
|
2011-04-20 |
2021-11-02 |
阿塞勒隆制药公司 |
内皮糖蛋白多肽及其用途
|
|
WO2012151317A1
(en)
|
2011-05-03 |
2012-11-08 |
Genentech, Inc. |
Vascular disruption agents and uses thereof
|
|
WO2012172054A1
(en)
|
2011-06-16 |
2012-12-20 |
Scil Proteins Gmbh |
Modified multimeric ubiquitin proteins binding vegf-a
|
|
EP2551348B1
(de)
|
2011-07-29 |
2014-09-24 |
Icon Genetics GmbH |
Produktion von galactosylierten N-Glycanen in Pflanzen
|
|
MX2014001736A
(es)
|
2011-08-17 |
2014-03-31 |
Genentech Inc |
Inhibicion de angiogenesis en tumores refractarios.
|
|
CA2850571C
(en)
|
2011-10-04 |
2021-01-05 |
Icon Genetics Gmbh |
Nicotiana benthamiana plants deficient in fucosyltransferase activity
|
|
ES2628321T3
(es)
|
2011-12-01 |
2017-08-02 |
Thrombogenics N.V. |
Mejora del resultado de una trabeculectomía
|
|
WO2013082511A1
(en)
|
2011-12-02 |
2013-06-06 |
Genentech, Inc. |
Methods for overcoming tumor resistance to vegf antagonists
|
|
US10364268B2
(en)
|
2011-12-22 |
2019-07-30 |
Genentech, Inc. |
Ion exchange membrane chromatography
|
|
SI2825558T1
(sl)
|
2012-03-13 |
2019-08-30 |
F. Hoffmann-La Roche Ag |
Kombinirana terapija za zdravljenje raka jajčnikov
|
|
RU2017139267A
(ru)
|
2012-03-27 |
2019-02-12 |
Дженентек, Инк. |
Усовершенствованные способы выделения рекомбинантных белков
|
|
JP6312659B2
(ja)
|
2012-05-31 |
2018-04-18 |
ジェネンテック, インコーポレイテッド |
Pd−1系結合アンタゴニスト及びvegfアンタゴニストを用いた癌の治療方法
|
|
LT3495387T
(lt)
|
2012-07-13 |
2021-11-25 |
Roche Glycart Ag |
Bispecifiniai anti-vegf / anti-ang-2 antikūnai ir jų panaudojimas akių kraujagyslių ligoms gydyti
|
|
RU2015104001A
(ru)
|
2012-08-07 |
2016-09-27 |
Дженентек, Инк. |
Комбинированная терапия для лечения глиобластомы
|
|
EP3929206A1
(de)
|
2012-11-15 |
2021-12-29 |
Apellis Pharmaceuticals, Inc. |
Langwirkende compstatin-analoga sowie verwandte zusammensetzungen und verfahren
|
|
EP2934602B1
(de)
|
2012-12-19 |
2019-02-27 |
Genentech, Inc. |
Verfahren und zusammensetzungen zur radiohalogen proteinmarkierung
|
|
MY199344A
(en)
|
2013-02-18 |
2023-10-24 |
Vegenics Pty Ltd |
Ligand binding molecules and uses thereof
|
|
CN105209069B
(zh)
|
2013-03-13 |
2019-08-23 |
豪夫迈·罗氏有限公司 |
抗体配制剂
|
|
US10308687B2
(en)
|
2013-03-15 |
2019-06-04 |
Apellis Pharmaceuticals, Inc. |
Cell-penetrating compstatin analogs and uses thereof
|
|
SG11201509596YA
(en)
|
2013-05-23 |
2015-12-30 |
Five Prime Therapeutics Inc |
Methods of treating cancer
|
|
KR102948178B1
(ko)
|
2013-07-12 |
2026-04-10 |
아스텔라스 유에스 엘엘씨 |
안과적 질환을 치료하거나 예방하기 위한 방법
|
|
US10617755B2
(en)
|
2013-08-30 |
2020-04-14 |
Genentech, Inc. |
Combination therapy for the treatment of glioblastoma
|
|
US10456470B2
(en)
|
2013-08-30 |
2019-10-29 |
Genentech, Inc. |
Diagnostic methods and compositions for treatment of glioblastoma
|
|
EA035481B1
(ru)
|
2013-10-25 |
2020-06-23 |
Акселерон Фарма, Инк. |
Эндоглиновые пептиды для лечения фиброзных заболеваний
|
|
ES2875878T3
(es)
|
2013-11-18 |
2021-11-11 |
Formycon Ag |
Composición farmacéutica de un anticuerpo anti-VEGF
|
|
CA2935423C
(en)
|
2014-01-24 |
2023-11-07 |
Dana-Farber Cancer Institute, Inc. |
Antibody molecules to pd-1 and uses thereof
|
|
AU2015210750B2
(en)
|
2014-01-31 |
2020-08-20 |
Children's Medical Center Corporation |
Antibody molecules to TIM-3 and uses thereof
|
|
WO2015138920A1
(en)
|
2014-03-14 |
2015-09-17 |
Novartis Ag |
Antibody molecules to lag-3 and uses thereof
|
|
MX2016012285A
(es)
|
2014-03-24 |
2017-01-23 |
Genentech Inc |
Tratamiento de cáncer con antagonista de c-met y correlación de estos con la expresión de hgf.
|
|
WO2015153514A1
(en)
|
2014-03-31 |
2015-10-08 |
Genentech, Inc. |
Combination therapy comprising anti-angiogenesis agents and ox40 binding agonists
|
|
RU2702748C2
(ru)
|
2014-05-12 |
2019-10-11 |
Формикон Аг |
Предварительно заполненный пластиковый шприц, содержащий антагонист vegf
|
|
WO2016007752A1
(en)
|
2014-07-09 |
2016-01-14 |
Genentech, Inc. |
Ph adjustment to improve thaw recovery of cell banks
|
|
JP2017523776A
(ja)
|
2014-07-14 |
2017-08-24 |
ジェネンテック, インコーポレイテッド |
膠芽腫の診断方法及びその治療用組成物
|
|
WO2016025647A1
(en)
|
2014-08-12 |
2016-02-18 |
Massachusetts Institute Of Technology |
Synergistic tumor treatment with il-2, a therapeutic antibody, and a cancer vaccine
|
|
WO2016025642A1
(en)
|
2014-08-12 |
2016-02-18 |
Massachusetts Institute Of Technology |
Synergistic tumor treatment with il-2 and integrin-binding-fc-fusion protein
|
|
JP6683686B2
(ja)
|
2014-08-22 |
2020-04-22 |
オークランド ユニサービシーズ リミティド |
チャネル調節剤
|
|
WO2016040882A1
(en)
|
2014-09-13 |
2016-03-17 |
Novartis Ag |
Combination therapies of egfr inhibitors
|
|
SG11201701821QA
(en)
|
2014-09-15 |
2017-04-27 |
Genentech Inc |
Antibody formulations
|
|
KR20170066546A
(ko)
|
2014-10-03 |
2017-06-14 |
노파르티스 아게 |
조합 요법
|
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
|
WO2016061142A1
(en)
|
2014-10-14 |
2016-04-21 |
Novartis Ag |
Antibody molecules to pd-l1 and uses thereof
|
|
AU2015346460A1
(en)
|
2014-11-10 |
2017-03-23 |
Genentech, Inc. |
Anti-interleukin-33 antibodies and uses thereof
|
|
EP3233918A1
(de)
|
2014-12-19 |
2017-10-25 |
Novartis AG |
Kombinationstherapien
|
|
HK1243141A1
(zh)
|
2014-12-23 |
2018-07-06 |
豪夫迈.罗氏有限公司 |
用於治疗和诊断化学疗法抗性癌症的组合物和方法
|
|
HK1251474A1
(zh)
|
2015-06-08 |
2019-02-01 |
豪夫迈‧罗氏有限公司 |
使用抗ox40抗体和pd-1轴结合拮抗剂治疗癌症的方法
|
|
WO2017019897A1
(en)
|
2015-07-29 |
2017-02-02 |
Novartis Ag |
Combination therapies comprising antibody molecules to tim-3
|
|
EP4378957A3
(de)
|
2015-07-29 |
2024-08-07 |
Novartis AG |
Kombinationstherapien mit antikörpermolekülen gegen pd-1
|
|
ES2878188T3
(es)
|
2015-07-29 |
2021-11-18 |
Novartis Ag |
Terapias de combinación que comprenden moléculas de anticuerpos contra LAG-3
|
|
CA3287719A1
(en)
|
2015-10-07 |
2026-03-02 |
Apellis Pharmaceuticals, Inc. |
Use of long-acting compstatin analog for treating a complement-mediated disorder
|
|
SG11201803356SA
(en)
|
2015-10-30 |
2018-05-30 |
Genentech Inc |
Anti-htra1 antibodies and methods of use thereof
|
|
KR20250099459A
(ko)
|
2015-11-03 |
2025-07-01 |
얀센 바이오테크 인코포레이티드 |
Pd-1과 특이적으로 결합하는 항체 및 그의 용도
|
|
WO2017085253A1
(en)
|
2015-11-18 |
2017-05-26 |
Formycon Ag |
Pre-filled plastic syringe containing a vegf antagonist
|
|
WO2018218013A2
(en)
|
2017-05-24 |
2018-11-29 |
Sio2 Medical Products, Inc. |
Sterilizable pharmaceutical package for ophthalmic formulations
|
|
AU2016356717B2
(en)
|
2015-11-18 |
2022-09-29 |
Sio2 Medical Products, Inc. |
Pharmaceutical package for ophthalmic formulations
|
|
RU2734958C2
(ru)
|
2015-11-18 |
2020-10-26 |
Формикон Аг |
Предварительно заполненная фармацевтическая упаковка, содержащая жидкий состав на основе антагониста vegf
|
|
EP3389712B1
(de)
|
2015-12-17 |
2024-04-10 |
Novartis AG |
Antikörpermoleküle gegen pd-1 und verwendungen davon
|
|
WO2017129685A1
(en)
|
2016-01-26 |
2017-08-03 |
Formycon Ag |
Liquid formulation of a vegf antagonist
|
|
CN109312299A
(zh)
|
2016-03-29 |
2019-02-05 |
格尔托公司 |
蛋白质在具有0.5:1至10:1的周质体积与细胞质体积比的革兰氏阴性菌中的表达
|
|
MX384141B
(es)
|
2016-04-15 |
2025-03-14 |
Genentech Inc |
Métodos para monitorear y terapias para usarse en tratar el cáncer.
|
|
JP2019515670A
(ja)
|
2016-04-15 |
2019-06-13 |
ジェネンテック, インコーポレイテッド |
がんをモニタリングし治療するための方法
|
|
JP2019524706A
(ja)
|
2016-07-08 |
2019-09-05 |
ジェネンテック, インコーポレイテッド |
Muc16陽性癌治療の応答性を評価するためのヒト精巣上体タンパク質4(he4)の使用
|
|
CN109890982B
(zh)
|
2016-07-08 |
2023-07-07 |
基因泰克公司 |
通过nrf2及其下游目标基因的表达状态和突变状态诊断和治疗癌症的方法
|
|
CN109689102A
(zh)
|
2016-08-12 |
2019-04-26 |
基因泰克公司 |
Mek抑制剂,pd-1轴抑制剂,和vegf抑制剂的组合疗法
|
|
US10603358B2
(en)
|
2017-01-10 |
2020-03-31 |
Nodus Therapeutics |
Combination tumor treatment with an integrin-binding-Fc fusion protein and immune stimulator
|
|
US10350266B2
(en)
|
2017-01-10 |
2019-07-16 |
Nodus Therapeutics, Inc. |
Method of treating cancer with a multiple integrin binding Fc fusion protein
|
|
CA3052670A1
(en)
|
2017-03-01 |
2018-09-07 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
|
CN116059313A
(zh)
|
2017-04-07 |
2023-05-05 |
阿佩利斯制药有限公司 |
给药方案以及相关组合物和方法
|
|
EP3630043A1
(de)
|
2017-05-24 |
2020-04-08 |
Formycon AG |
Sterilisierbare vorgefüllte pharmazeutische verpackungen mit einer flüssigen formulierung eines vegf-antagonisten
|
|
WO2018215580A1
(en)
|
2017-05-24 |
2018-11-29 |
Formycon Ag |
Method for sterilizing prefilled plastic syringes containing a vegf antagonist
|
|
US11312783B2
(en)
|
2017-06-22 |
2022-04-26 |
Novartis Ag |
Antibody molecules to CD73 and uses thereof
|
|
WO2018237173A1
(en)
|
2017-06-22 |
2018-12-27 |
Novartis Ag |
ANTIBODY MOLECULES DIRECTED AGAINST CD73 AND CORRESPONDING USES
|
|
WO2019020777A1
(en)
|
2017-07-26 |
2019-01-31 |
Formycon Ag |
LIQUID FORMULATION OF A VEGF ANTAGONIST
|
|
US11180541B2
(en)
|
2017-09-28 |
2021-11-23 |
Geltor, Inc. |
Recombinant collagen and elastin molecules and uses thereof
|
|
KR20240167712A
(ko)
|
2017-12-15 |
2024-11-27 |
아펠리스 파마슈티컬스 인코포레이티드 |
투여 요법 및 관련 조성물 및 방법
|
|
US12398209B2
(en)
|
2018-01-22 |
2025-08-26 |
Janssen Biotech, Inc. |
Methods of treating cancers with antagonistic anti-PD-1 antibodies
|
|
WO2019154776A1
(en)
|
2018-02-06 |
2019-08-15 |
F. Hoffmann-La Roche Ag |
Treatment of ophthalmologic diseases
|
|
CN111989095A
(zh)
|
2018-04-16 |
2020-11-24 |
上海岸阔医药科技有限公司 |
预防或治疗肿瘤疗法副作用的方法
|
|
MA52777A
(fr)
|
2018-05-24 |
2021-04-14 |
Janssen Biotech Inc |
Agents de liaison psma et utilisations correspondantes
|
|
UY38247A
(es)
|
2018-05-30 |
2019-12-31 |
Novartis Ag |
Anticuerpos frente a entpd2, terapias de combinación y métodos de uso de los anticuerpos y las terapias de combinación
|
|
US20210214459A1
(en)
|
2018-05-31 |
2021-07-15 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
RS65472B1
(sr)
|
2018-07-03 |
2024-05-31 |
Bristol Myers Squibb Co |
Postupak proizvodnje rekombinantnih proteina
|
|
US12415980B2
(en)
|
2018-10-10 |
2025-09-16 |
Boehringer Ingelheim International Gmbh |
Method for membrane gas transfer in high density bioreactor culture
|
|
AU2019361983A1
(en)
|
2018-10-18 |
2021-05-20 |
Genentech, Inc. |
Diagnostic and therapeutic methods for sarcomatoid kidney cancer
|
|
JP7453151B2
(ja)
|
2018-11-02 |
2024-03-19 |
協和キリン株式会社 |
液体培地の調製方法
|
|
WO2020109343A1
(en)
|
2018-11-29 |
2020-06-04 |
F. Hoffmann-La Roche Ag |
Combination therapy for treatment of macular degeneration
|
|
AU2020254582B2
(en)
|
2019-04-01 |
2025-12-18 |
Genentech, Inc. |
Compositions and methods for stabilizing protein-containing formulations
|
|
TW202104254A
(zh)
|
2019-04-12 |
2021-02-01 |
美商格爾托公司 |
重組彈性蛋白及其生產
|
|
AR118720A1
(es)
|
2019-04-19 |
2021-10-27 |
Janssen Biotech Inc |
Métodos para tratar el cáncer de próstata con un anticuerpo anti-psma / cd3
|
|
KR20220004744A
(ko)
|
2019-05-03 |
2022-01-11 |
제넨테크, 인크. |
항-pd-l1 항체를 이용하여 암을 치료하는 방법
|
|
MA54325A
(fr)
|
2019-06-05 |
2022-05-11 |
Regeneron Pharma |
Dispositifs et procédés pour l'administration précise de doses
|
|
EP4007808A1
(de)
|
2019-08-01 |
2022-06-08 |
Bristol-Myers Squibb Company |
Verfahren zur verbesserung der proteinproduktivität in fed-batch-zellkulturen
|
|
JP2022548881A
(ja)
|
2019-09-18 |
2022-11-22 |
ノバルティス アーゲー |
Entpd2抗体、組合せ療法並びに抗体及び組合せ療法を使用する方法
|
|
WO2021100034A1
(en)
|
2019-11-19 |
2021-05-27 |
Protalix Ltd. |
Removal of constructs from transformed cells
|
|
JP7767298B2
(ja)
|
2020-03-13 |
2025-11-11 |
ジェネンテック, インコーポレイテッド |
抗インターロイキン-33抗体及びその使用
|
|
WO2021191870A1
(en)
|
2020-03-27 |
2021-09-30 |
Dcprime B.V. |
Ex vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy
|
|
CN115698717A
(zh)
|
2020-04-03 |
2023-02-03 |
基因泰克公司 |
癌症的治疗和诊断方法
|
|
KR20230033647A
(ko)
|
2020-06-30 |
2023-03-08 |
멘두스 비.브이. |
난소암 백신에서 백혈병 유래 세포의 용도
|
|
US12486525B2
(en)
|
2020-09-22 |
2025-12-02 |
Bristol-Myers Squibb Company |
Methods for increasing productivity of therapeutic proteins
|
|
WO2022074646A1
(en)
|
2020-10-05 |
2022-04-14 |
Protalix Ltd. |
Dicer-like knock-out plant cells
|
|
CN116568326A
(zh)
|
2020-11-13 |
2023-08-08 |
基因泰克公司 |
用于治疗实体瘤的方法及包括krasg12c抑制剂和vegf抑制剂的组合物
|
|
AU2022211682A1
(en)
|
2021-01-22 |
2023-08-03 |
Mendus B.V. |
Methods of tumor vaccination
|
|
KR20230137393A
(ko)
|
2021-01-28 |
2023-10-04 |
얀센 바이오테크 인코포레이티드 |
Psma 결합 단백질 및 이의 용도
|
|
WO2022190058A1
(en)
|
2021-03-12 |
2022-09-15 |
Dcprime B.V. |
Methods of vaccination and use of cd47 blockade
|
|
WO2022231930A1
(en)
|
2021-04-26 |
2022-11-03 |
Celanese Eva Performance Polymers Llc |
Implantable device for sustained release of a macromolecular drug compound
|
|
WO2022232503A1
(en)
|
2021-04-30 |
2022-11-03 |
Genentech, Inc. |
Therapeutic and diagnostic methods and compositions for cancer
|
|
CA3223534A1
(en)
|
2021-07-02 |
2023-01-05 |
Genentech, Inc. |
Methods and compositions for treating cancer
|
|
KR20240038008A
(ko)
|
2021-07-28 |
2024-03-22 |
에프. 호프만-라 로슈 아게 |
암 치료 방법 및 조성물
|
|
US20250115666A1
(en)
|
2021-08-05 |
2025-04-10 |
Bristol-Myers Squibb Company |
Cell culture methods for producing therapeutic proteins
|
|
IT202100023357A1
(it)
|
2021-09-09 |
2023-03-09 |
Cheirontech S R L |
Peptidi con attività anti-angiogenica
|
|
US20240390869A1
(en)
|
2021-09-21 |
2024-11-28 |
Bristol-Myers Squibb Company |
Methods of controlling the level of dissolved oxygen (do) in a solution comprising a recombinant protein in a storage container
|
|
WO2023080900A1
(en)
|
2021-11-05 |
2023-05-11 |
Genentech, Inc. |
Methods and compositions for classifying and treating kidney cancer
|
|
KR20240144944A
(ko)
|
2022-01-28 |
2024-10-04 |
온퀄리티 파마슈티컬스 차이나 리미티드 |
항종양제와 관련된 질병 또는 증상을 예방하거나 치료하는 방법
|
|
US20250188088A1
(en)
|
2022-02-21 |
2025-06-12 |
Onquality Pharmaceuticals China Ltd. |
Compound and use thereof
|
|
EP4514845A1
(de)
|
2022-04-29 |
2025-03-05 |
Broadwing Bio LLC |
Bispezifische antikörper und verfahren zur behandlung von augenerkrankungen
|
|
USD1120314S1
(en)
|
2022-11-30 |
2026-03-24 |
Regeneron Pharmaceuticals, Inc. |
Dose delivery device
|
|
WO2024263904A1
(en)
|
2023-06-23 |
2024-12-26 |
Genentech, Inc. |
Methods for treatment of liver cancer
|
|
WO2024263195A1
(en)
|
2023-06-23 |
2024-12-26 |
Genentech, Inc. |
Methods for treatment of liver cancer
|