GEP20032898B - Integrin Receptor Antagonists, Pharmaceutical Composition Containing the Same and Methods for Treatment - Google Patents

Integrin Receptor Antagonists, Pharmaceutical Composition Containing the Same and Methods for Treatment

Info

Publication number
GEP20032898B
GEP20032898B GE4041A GEAP1998005455A GEP20032898B GE P20032898 B GEP20032898 B GE P20032898B GE 4041 A GE4041 A GE 4041A GE AP1998005455 A GEAP1998005455 A GE AP1998005455A GE P20032898 B GEP20032898 B GE P20032898B
Authority
GE
Georgia
Prior art keywords
integrin receptor
treatment
methods
receptor antagonists
alpha
Prior art date
Application number
GE4041A
Inventor
Mark E Duggan
Robert S Meissner
John H Hutchinson
Wasyl Halczenko
Ben C Askew
Paul J Coleman
Michael A Patane
Jiabing Wang
James J Perkins
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9810182.7A external-priority patent/GB9810182D0/en
Priority claimed from GBGB9810882.2A external-priority patent/GB9810882D0/en
Priority claimed from GBGB9810892.1A external-priority patent/GB9810892D0/en
Priority claimed from GBGB9811283.2A external-priority patent/GB9811283D0/en
Priority claimed from GBGB9812686.5A external-priority patent/GB9812686D0/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of GEP20032898B publication Critical patent/GEP20032898B/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1. Technical Result Increase in efficiency of treatment of diseases caused by integrin receptor. 2. Essence Compounds and derivatives, the structural formulas of which are provided in the description, are integrin receptor antagonists, more particularly, the antagonists of the integrin receptors alpha vbeta3, alpha vbeta5 and alpha vbeta6. Pharmaceutical compositions containing them and methods of treating bone resorption, osteoporosis, vascular restenosis, diabetic retinopathy, macular degeneration, inflammation and diseases caused by tumor growth and metastasis are disclosed. 3. Field of Application Medicine.
GE4041A 1997-12-17 1998-12-14 Integrin Receptor Antagonists, Pharmaceutical Composition Containing the Same and Methods for Treatment GEP20032898B (en)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US6991097P 1997-12-17 1997-12-17
US7919798P 1998-03-24 1998-03-24
US7994498P 1998-03-30 1998-03-30
US8039798P 1998-04-02 1998-04-02
US8325198P 1998-04-27 1998-04-27
GBGB9810182.7A GB9810182D0 (en) 1998-05-13 1998-05-13 Vitronectin receptor antagonists
GBGB9810882.2A GB9810882D0 (en) 1998-05-20 1998-05-20 Vitronectin receptor antagonists
GBGB9810892.1A GB9810892D0 (en) 1998-05-20 1998-05-20 Vitronectin receptor antagonists
GBGB9811283.2A GB9811283D0 (en) 1998-05-26 1998-05-26 Vironectin receptor antagonists
GBGB9812686.5A GB9812686D0 (en) 1998-06-12 1998-06-12 Vitronectin receptor antagonists
US9258898P 1998-07-13 1998-07-13

Publications (1)

Publication Number Publication Date
GEP20032898B true GEP20032898B (en) 2002-09-10

Family

ID=45477317

Family Applications (1)

Application Number Title Priority Date Filing Date
GE4041A GEP20032898B (en) 1997-12-17 1998-12-14 Integrin Receptor Antagonists, Pharmaceutical Composition Containing the Same and Methods for Treatment

Country Status (1)

Country Link
GE (1) GEP20032898B (en)

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