HUE026136T2 - Functional influenza virus-like particles (VLP-K) - Google Patents

Functional influenza virus-like particles (VLP-K) Download PDF

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Publication number
HUE026136T2
HUE026136T2 HUE06826264A HUE06826264A HUE026136T2 HU E026136 T2 HUE026136 T2 HU E026136T2 HU E06826264 A HUE06826264 A HU E06826264A HU E06826264 A HUE06826264 A HU E06826264A HU E026136 T2 HUE026136 T2 HU E026136T2
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HU
Hungary
Prior art keywords
influenza
vlp
vlps
virus
protein
Prior art date
Application number
HUE06826264A
Other languages
English (en)
Hungarian (hu)
Inventor
Gale Smith
Rick Bright
Peter Pushko
Jinyou Zhang
Kutub Mahmood
Original Assignee
Novavax Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novavax Inc filed Critical Novavax Inc
Publication of HUE026136T2 publication Critical patent/HUE026136T2/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08RNA viruses
    • C07K14/11Orthomyxoviridae, e.g. influenza virus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5258Virus-like particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16123Virus like particles [VLP]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
HUE06826264A 2005-10-18 2006-10-18 Functional influenza virus-like particles (VLP-K) HUE026136T2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US72751305P 2005-10-18 2005-10-18
US78084706P 2006-03-10 2006-03-10
US80000606P 2006-05-15 2006-05-15
US83119606P 2006-07-17 2006-07-17
US83211606P 2006-07-21 2006-07-21
US84549506P 2006-09-19 2006-09-19

Publications (1)

Publication Number Publication Date
HUE026136T2 true HUE026136T2 (en) 2016-05-30

Family

ID=37963272

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE06826264A HUE026136T2 (en) 2005-10-18 2006-10-18 Functional influenza virus-like particles (VLP-K)

Country Status (19)

Country Link
EP (1) EP1937301B1 (OSRAM)
JP (5) JP5714799B2 (OSRAM)
KR (1) KR101359723B1 (OSRAM)
CN (2) CN103865892B (OSRAM)
AU (1) AU2006304640B2 (OSRAM)
BR (1) BRPI0617486A2 (OSRAM)
CA (1) CA2625406C (OSRAM)
DK (1) DK1937301T3 (OSRAM)
ES (1) ES2543056T3 (OSRAM)
HU (1) HUE026136T2 (OSRAM)
IL (1) IL190775A (OSRAM)
NZ (1) NZ567164A (OSRAM)
PL (1) PL1937301T3 (OSRAM)
PT (1) PT1937301E (OSRAM)
RU (1) RU2483751C2 (OSRAM)
SG (1) SG2014012868A (OSRAM)
SI (1) SI1937301T1 (OSRAM)
TW (1) TWI488968B (OSRAM)
WO (1) WO2007047831A2 (OSRAM)

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Also Published As

Publication number Publication date
PL1937301T3 (pl) 2015-10-30
PT1937301E (pt) 2015-09-14
KR101359723B1 (ko) 2014-02-05
SG2014012868A (en) 2014-09-26
WO2007047831A2 (en) 2007-04-26
EP1937301B1 (en) 2015-04-22
EP1937301A4 (en) 2009-06-24
WO2007047831A3 (en) 2007-07-19
AU2006304640A1 (en) 2007-04-26
JP2012157367A (ja) 2012-08-23
IL190775A (en) 2016-04-21
EP1937301A2 (en) 2008-07-02
ES2543056T3 (es) 2015-08-14
JP2016135142A (ja) 2016-07-28
CN101325966A (zh) 2008-12-17
NZ567164A (en) 2012-06-29
JP2009511084A (ja) 2009-03-19
JP5714799B2 (ja) 2015-05-07
AU2006304640B2 (en) 2012-10-11
CN103865892B (zh) 2017-04-12
BRPI0617486A2 (pt) 2011-07-26
RU2008119501A (ru) 2009-11-27
SI1937301T1 (sl) 2015-08-31
CA2625406A1 (en) 2007-04-26
CA2625406C (en) 2016-08-09
JP2017189178A (ja) 2017-10-19
CN103865892A (zh) 2014-06-18
KR20080081901A (ko) 2008-09-10
DK1937301T3 (en) 2015-07-20
JP5771558B2 (ja) 2015-09-02
IL190775A0 (en) 2008-11-03
JP2015083018A (ja) 2015-04-30
RU2483751C2 (ru) 2013-06-10
TW200732476A (en) 2007-09-01
TWI488968B (zh) 2015-06-21
CN101325966B (zh) 2014-04-09
HK1121687A1 (en) 2009-04-30

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