PL1937301T3 - Funkcjonalne cząsteczki podobne do wirusa grypy (VLP) - Google Patents

Funkcjonalne cząsteczki podobne do wirusa grypy (VLP)

Info

Publication number
PL1937301T3
PL1937301T3 PL06826264T PL06826264T PL1937301T3 PL 1937301 T3 PL1937301 T3 PL 1937301T3 PL 06826264 T PL06826264 T PL 06826264T PL 06826264 T PL06826264 T PL 06826264T PL 1937301 T3 PL1937301 T3 PL 1937301T3
Authority
PL
Poland
Prior art keywords
vlps
particles
influenza virus
functional influenza
functional
Prior art date
Application number
PL06826264T
Other languages
English (en)
Inventor
Gale Smith
Rick Bright
Peter Pushko
Jinyou Zhang
Kutub Mahmood
Original Assignee
Novavax Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novavax Inc filed Critical Novavax Inc
Publication of PL1937301T3 publication Critical patent/PL1937301T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/11—Orthomyxoviridae, e.g. influenza virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5258—Virus-like particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16123—Virus like particles [VLP]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
PL06826264T 2005-10-18 2006-10-18 Funkcjonalne cząsteczki podobne do wirusa grypy (VLP) PL1937301T3 (pl)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US72751305P 2005-10-18 2005-10-18
US78084706P 2006-03-10 2006-03-10
US80000606P 2006-05-15 2006-05-15
US83119606P 2006-07-17 2006-07-17
US83211606P 2006-07-21 2006-07-21
US84549506P 2006-09-19 2006-09-19
EP20060826264 EP1937301B1 (en) 2005-10-18 2006-10-18 Functional influenza virus like particles (vlps)
PCT/US2006/040862 WO2007047831A2 (en) 2005-10-18 2006-10-18 Functional influenza virus like particles (vlps)

Publications (1)

Publication Number Publication Date
PL1937301T3 true PL1937301T3 (pl) 2015-10-30

Family

ID=37963272

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06826264T PL1937301T3 (pl) 2005-10-18 2006-10-18 Funkcjonalne cząsteczki podobne do wirusa grypy (VLP)

Country Status (20)

Country Link
EP (1) EP1937301B1 (pl)
JP (5) JP5714799B2 (pl)
KR (1) KR101359723B1 (pl)
CN (2) CN101325966B (pl)
AU (1) AU2006304640B2 (pl)
BR (1) BRPI0617486A2 (pl)
CA (1) CA2625406C (pl)
DK (1) DK1937301T3 (pl)
ES (1) ES2543056T3 (pl)
HK (1) HK1121687A1 (pl)
HU (1) HUE026136T2 (pl)
IL (1) IL190775A (pl)
NZ (1) NZ567164A (pl)
PL (1) PL1937301T3 (pl)
PT (1) PT1937301E (pl)
RU (1) RU2483751C2 (pl)
SG (1) SG2014012868A (pl)
SI (1) SI1937301T1 (pl)
TW (1) TWI488968B (pl)
WO (1) WO2007047831A2 (pl)

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US9101578B2 (en) 2006-05-01 2015-08-11 Technovax, Inc. Polyvalent influenza virus-like particle (VLP) compositions
US8778353B2 (en) 2006-05-01 2014-07-15 Technovax, Inc. Influenza virus-like particle (VLP) compositions
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US8202967B2 (en) 2006-10-27 2012-06-19 Boehringer Ingelheim Vetmedica, Inc. H5 proteins, nucleic acid molecules and vectors encoding for those, and their medicinal use
CA2615372A1 (en) * 2007-07-13 2009-01-13 Marc-Andre D'aoust Influenza virus-like particles (vlps) comprising hemagglutinin
ES2542644T3 (es) * 2007-07-19 2015-08-07 Novavax, Inc. VLPS quiméricas de la gripe aviar
US9592285B2 (en) * 2007-11-12 2017-03-14 The Trustees Of The University Of Pennsylvania Vaccines against multiple subtypes of influenza virus
EP2610345B1 (en) 2007-11-27 2015-08-19 Medicago Inc. Recombinant influenza virus-like particles (VLPS) produced in transgenic plants expressing hemagglutinin
PT2294202E (pt) 2008-07-08 2015-10-09 Medicago Inc Antigénios gripais recombinantes solúveis
CN102165062B (zh) * 2008-07-18 2017-09-08 麦迪卡格公司 新的流感病毒免疫表位
MX2011005604A (es) * 2008-11-28 2011-09-01 Merial Ltd Vacuna recombinante para influenza aviar y sus usos.
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SI2445928T1 (en) 2009-06-24 2018-05-31 Medicago Inc. HYPER PARTICULARS, SIMILAR VIRUSES OF GRIPE, WHICH HAVE EXPOSED HEMAGLUTININE
KR102115226B1 (ko) 2009-09-22 2020-05-27 메디카고 인코포레이티드 식물-유래 단백질의 제조방법
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US10130697B2 (en) 2010-03-23 2018-11-20 Wisconsin Alumni Research Foundation (Warf) Vaccines comprising mutant attenuated influenza viruses
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CN101947317B (zh) * 2010-09-27 2012-05-30 武汉大学 一种h5n1禽流感病毒样颗粒疫苗的规模化制备方法
CN102676461A (zh) * 2011-03-17 2012-09-19 中国科学院上海巴斯德研究所 一种利用果蝇细胞生产病毒样颗粒的方法及应用
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US10494613B2 (en) 2015-08-28 2019-12-03 Wisconsin Alumni Research Foundation (Warf) Generation of infectious influenza viruses from virus-like particles
RU2639491C2 (ru) * 2015-08-31 2017-12-21 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Вирионы и вирусоподобные частицы вируса мозаики альтернантеры как усилители иммунного ответа
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CN107353328A (zh) * 2017-08-23 2017-11-17 上海市动物疫病预防控制中心 一种重组的h9n2亚型禽流感病毒样颗粒及其制备方法和用途
CN110240634B (zh) * 2018-03-08 2022-09-06 普莱柯生物工程股份有限公司 一种禽流感病毒样颗粒疫苗、及其制备方法和应用
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KR102151962B1 (ko) * 2020-03-24 2020-09-04 안병철 어린 포유동물의 전염성 질병을 예방 또는 치료하기 위한 혈청 조성물의 제조방법, 상기 방법에 의해 제조된 혈청 조성물 및 이의 용도
US20230125824A1 (en) * 2020-03-24 2023-04-27 Byung Chul Ahn Method for producing serum composition for preventing or treating mucosarelated infectious disease in young mammals, serum composition produced thereby, and use thereof
CN113461786B (zh) * 2020-03-30 2022-09-13 普莱柯生物工程股份有限公司 一种禽流感病毒样颗粒疫苗、及其制备方法和应用
KR20230005313A (ko) 2020-05-01 2023-01-09 사이노셀테크 엘티디. 단백질/펩타이드 항원의 면역원성 개선 방법
CN112342149A (zh) * 2020-11-12 2021-02-09 新疆畜牧科学院兽医研究所（新疆畜牧科学院动物临床医学研究中心） 一种禽流感病毒样颗粒组装表达系统及其应用
CN112979796A (zh) * 2021-04-27 2021-06-18 军事科学院军事医学研究院军事兽医研究所 马抗甲型h5n1虎源流感病毒免疫球蛋白和特异性免疫球蛋白及其精制方法
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Also Published As

Publication number Publication date
JP2015083018A (ja) 2015-04-30
JP2017189178A (ja) 2017-10-19
NZ567164A (en) 2012-06-29
BRPI0617486A2 (pt) 2011-07-26
TWI488968B (zh) 2015-06-21
CN103865892A (zh) 2014-06-18
TW200732476A (en) 2007-09-01
AU2006304640A1 (en) 2007-04-26
ES2543056T3 (es) 2015-08-14
SI1937301T1 (sl) 2015-08-31
IL190775A (en) 2016-04-21
CA2625406C (en) 2016-08-09
WO2007047831A3 (en) 2007-07-19
KR101359723B1 (ko) 2014-02-05
JP5714799B2 (ja) 2015-05-07
PT1937301E (pt) 2015-09-14
AU2006304640B2 (en) 2012-10-11
JP2016135142A (ja) 2016-07-28
SG2014012868A (en) 2014-09-26
CN101325966A (zh) 2008-12-17
EP1937301A2 (en) 2008-07-02
WO2007047831A2 (en) 2007-04-26
JP2009511084A (ja) 2009-03-19
JP2012157367A (ja) 2012-08-23
HK1121687A1 (en) 2009-04-30
RU2483751C2 (ru) 2013-06-10
EP1937301B1 (en) 2015-04-22
CN103865892B (zh) 2017-04-12
CN101325966B (zh) 2014-04-09
RU2008119501A (ru) 2009-11-27
HUE026136T2 (en) 2016-05-30
IL190775A0 (en) 2008-11-03
CA2625406A1 (en) 2007-04-26
KR20080081901A (ko) 2008-09-10
EP1937301A4 (en) 2009-06-24
DK1937301T3 (en) 2015-07-20
JP5771558B2 (ja) 2015-09-02

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