HRP20180223T4 - Kombinacija spoja akt-inhibitora i abiraterona za primjenu u terapeutskim postupcima - Google Patents

Kombinacija spoja akt-inhibitora i abiraterona za primjenu u terapeutskim postupcima Download PDF

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Publication number
HRP20180223T4
HRP20180223T4 HRP20180223TT HRP20180223T HRP20180223T4 HR P20180223 T4 HRP20180223 T4 HR P20180223T4 HR P20180223T T HRP20180223T T HR P20180223TT HR P20180223 T HRP20180223 T HR P20180223T HR P20180223 T4 HRP20180223 T4 HR P20180223T4
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Croatia
Prior art keywords
compound
combination
use according
abiraterone
cancer
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HRP20180223TT
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English (en)
Croatian (hr)
Inventor
Michelle NANNINI
Deepak Sampath
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Genentech, Inc.
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46931958&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20180223(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech, Inc. filed Critical Genentech, Inc.
Publication of HRP20180223T1 publication Critical patent/HRP20180223T1/hr
Publication of HRP20180223T4 publication Critical patent/HRP20180223T4/hr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/28—Compounds containing heavy metals
    • A61K31/282—Platinum compounds
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
    • A—HUMAN NECESSITIES
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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HRP20180223TT 2011-04-01 2012-03-30 Kombinacija spoja akt-inhibitora i abiraterona za primjenu u terapeutskim postupcima HRP20180223T4 (hr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161470624P 2011-04-01 2011-04-01
US201161470803P 2011-04-01 2011-04-01
EP12764765.9A EP2694072B2 (en) 2011-04-01 2012-03-30 Combination of akt inhibitor compound and abiraterone for use in therapeutic treatments
PCT/US2012/031679 WO2012135759A1 (en) 2011-04-01 2012-03-30 Combinations of akt inhibitor compounds and abiraterone, and methods of use

Publications (2)

Publication Number Publication Date
HRP20180223T1 HRP20180223T1 (hr) 2018-03-09
HRP20180223T4 true HRP20180223T4 (hr) 2024-10-11

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HRP20180223TT HRP20180223T4 (hr) 2011-04-01 2012-03-30 Kombinacija spoja akt-inhibitora i abiraterona za primjenu u terapeutskim postupcima

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US (7) US20150064171A1 (enExample)
EP (4) EP2694071B1 (enExample)
JP (4) JP6143739B2 (enExample)
KR (4) KR101950044B1 (enExample)
CN (8) CN103841975A (enExample)
AU (4) AU2012236166A1 (enExample)
BR (4) BR112013025354A2 (enExample)
CA (4) CA2831937A1 (enExample)
DK (1) DK2694072T4 (enExample)
ES (3) ES2657750T3 (enExample)
FI (1) FI2694072T4 (enExample)
HK (1) HK1204575A1 (enExample)
HR (1) HRP20180223T4 (enExample)
HU (1) HUE036513T2 (enExample)
IL (4) IL228638A0 (enExample)
LT (1) LT2694072T (enExample)
ME (1) ME02998B (enExample)
MX (4) MX354509B (enExample)
MY (1) MY179607A (enExample)
PL (2) PL2694485T3 (enExample)
PT (1) PT2694072T (enExample)
RS (1) RS56759B2 (enExample)
RU (4) RU2631240C2 (enExample)
SG (5) SG10201504303SA (enExample)
SI (1) SI2694072T2 (enExample)
SM (1) SMT201800250T1 (enExample)
TR (1) TR201802093T4 (enExample)
WO (4) WO2012135753A1 (enExample)
ZA (4) ZA201308062B (enExample)

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AU2009204483B2 (en) 2008-01-04 2014-03-13 Intellikine, Llc Certain chemical entities, compositions and methods
US8193182B2 (en) 2008-01-04 2012-06-05 Intellikine, Inc. Substituted isoquinolin-1(2H)-ones, and methods of use thereof
US9447049B2 (en) 2010-03-01 2016-09-20 University Of Tennessee Research Foundation Compounds for treatment of cancer
UA105005C2 (uk) 2008-06-16 2014-04-10 Юніверсіті Оф Теннессі Рісерч Фаундейшн Сполуки для лікування раку
US11084811B2 (en) 2010-03-01 2021-08-10 Oncternal Therapeutics, Inc. Compounds for treatment of cancer
KR20180080358A (ko) 2011-01-10 2018-07-11 인피니티 파마슈티칼스, 인코포레이티드 이소퀴놀린온 및 이의 고체 형태의 제조 방법
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