HK59397A - Paroxetine hydrochloride anhydrate substantially free of bound organic solvent - Google Patents

Paroxetine hydrochloride anhydrate substantially free of bound organic solvent

Info

Publication number
HK59397A
HK59397A HK59397A HK59397A HK59397A HK 59397 A HK59397 A HK 59397A HK 59397 A HK59397 A HK 59397A HK 59397 A HK59397 A HK 59397A HK 59397 A HK59397 A HK 59397A
Authority
HK
Hong Kong
Prior art keywords
organic solvent
substantially free
paroxetine hydrochloride
hydrochloride anhydrate
bound organic
Prior art date
Application number
HK59397A
Other languages
English (en)
Inventor
Victor Witold Jacewicz
Neal Ward
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27267578&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK59397(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9502297.6A external-priority patent/GB9502297D0/en
Priority claimed from GBGB9503112.6A external-priority patent/GB9503112D0/en
Priority claimed from GBGB9509807.5A external-priority patent/GB9509807D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of HK59397A publication Critical patent/HK59397A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK59397A 1995-02-06 1997-05-08 Paroxetine hydrochloride anhydrate substantially free of bound organic solvent HK59397A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9502297.6A GB9502297D0 (en) 1995-02-06 1995-02-06 Novel compound
GBGB9503112.6A GB9503112D0 (en) 1995-02-17 1995-02-17 Novel compound
GBGB9509807.5A GB9509807D0 (en) 1995-05-15 1995-05-15 Novel compounds

Publications (1)

Publication Number Publication Date
HK59397A true HK59397A (en) 1997-05-16

Family

ID=27267578

Family Applications (1)

Application Number Title Priority Date Filing Date
HK59397A HK59397A (en) 1995-02-06 1997-05-08 Paroxetine hydrochloride anhydrate substantially free of bound organic solvent

Country Status (47)

Country Link
EP (3) EP0808314B1 (ja)
JP (2) JP2915338B2 (ja)
KR (1) KR100289885B1 (ja)
CN (3) CN1090187C (ja)
AR (2) AR001982A1 (ja)
AT (1) AT407528B (ja)
AU (2) AU701518C (ja)
BE (1) BE1009112A3 (ja)
BG (1) BG62967B1 (ja)
BR (1) BR9600534A (ja)
CA (4) CA2211522C (ja)
CH (3) CH689229A5 (ja)
CZ (1) CZ297171B6 (ja)
DE (3) DE69621777T2 (ja)
DK (2) DK11996A (ja)
DZ (1) DZ1989A1 (ja)
ES (1) ES2114471B1 (ja)
FI (3) FI111544B (ja)
FR (1) FR2730232B1 (ja)
GR (1) GR1002466B (ja)
HK (1) HK59397A (ja)
HU (1) HUP9600255A1 (ja)
IE (1) IE80500B1 (ja)
IL (1) IL117035A (ja)
IT (1) IT1289532B1 (ja)
LU (1) LU88711A1 (ja)
LV (1) LV11618B (ja)
MA (1) MA23802A1 (ja)
MC (1) MC2411A1 (ja)
MX (1) MX9600484A (ja)
MY (1) MY132529A (ja)
NL (1) NL1002248C2 (ja)
NO (3) NO301009B1 (ja)
NZ (1) NZ280943A (ja)
OA (1) OA10261A (ja)
PL (1) PL189247B1 (ja)
PT (1) PT101827B (ja)
RO (1) RO112426B1 (ja)
RU (1) RU2125052C1 (ja)
SE (1) SE521084C2 (ja)
SG (1) SG43787A1 (ja)
SI (2) SI21923B (ja)
SK (1) SK283608B6 (ja)
TR (1) TR199600096A2 (ja)
TW (1) TW503238B (ja)
UA (1) UA49796C2 (ja)
WO (1) WO1996024595A1 (ja)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3882224B2 (ja) 1996-05-31 2007-02-14 旭硝子株式会社 パロキセチンの製造方法
DE69739561D1 (de) * 1996-06-13 2009-10-15 Sumitomo Chemical Co Piperidin Derivative als Zwischenprodukte zur Herstellung von Paroxetine und Verfahren zu ihrer Herstellung
JP2000514653A (ja) * 1996-07-15 2000-11-07 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 立体特異的分割のためのエステラーゼのスクリーニングおよびその使用
US5672612A (en) * 1996-09-09 1997-09-30 Pentech Pharmaceuticals, Inc. Amorphous paroxetine composition
US6638948B1 (en) 1996-09-09 2003-10-28 Pentech Pharmaceuticals, Inc. Amorphous paroxetine composition
CA2193939C (en) * 1996-12-24 2002-02-12 K.S. Keshava Murthy Useful form of anhydrous paroxetine hydrochloride
AU3108097A (en) 1997-06-10 1998-12-30 Synthon B.V. 4-phenylpiperidine compounds
ATE207065T1 (de) * 1997-08-08 2001-11-15 Aventis Pharma Gmbh Kristallform von n-(4-trifluormethylphenyl)-5- methylisoxazol-4-carbonsäureamid
GB9726907D0 (en) * 1997-12-19 1998-02-18 Smithkline Beecham Plc Novel compounds
BR9908825A (pt) * 1998-03-16 2000-11-21 Smithkline Beecham Plc Forma cristalina de paroxetina
GB9806312D0 (en) * 1998-03-24 1998-05-20 Smithkline Beecham Plc Novel formulations
US6699882B2 (en) 1998-03-24 2004-03-02 Smithkline Beecham P.L.C. Paroxetine compositions
AU2003200534B2 (en) * 1998-03-24 2004-12-02 Smithkline Beecham Plc Paroxetine compositions
JP3796351B2 (ja) 1998-04-13 2006-07-12 住友化学株式会社 パロキセチン塩酸塩無水和物の乾燥方法
GB9812941D0 (en) * 1998-06-16 1998-08-12 Smithkline Beecham Plc Method of treatment
CH689805A8 (fr) * 1998-07-02 2000-02-29 Smithkline Beecham Plc Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant.
ES2138937B1 (es) 1998-07-07 2000-10-01 Medichem Sa Polimorfo de maleato de paroxetina y formulaciones farmaceuticas que lo contienen.
PL345885A1 (en) * 1998-08-07 2002-01-14 Smithkline Beecham Plc Process for the preparation of a non-crystalline anhydrate form of paroxetine hydrochloride
GB9824298D0 (en) * 1998-11-05 1998-12-30 Smithkline Beecham Plc Novel process
GB9826176D0 (en) * 1998-11-28 1999-01-20 Smithkline Beecham Plc Novel process
GB9826175D0 (en) * 1998-11-28 1999-01-20 Smithkline Beecham Plc Novel process
GB9826178D0 (en) * 1998-11-30 1999-01-20 Smithkline Beecham Plc Novel process
GB9826242D0 (en) * 1998-11-30 1999-01-20 Smithkline Beecham Plc Novel process
GB9826180D0 (en) * 1998-11-30 1999-01-20 Smithkline Beecham Plc Novel process
JP2002531452A (ja) * 1998-11-30 2002-09-24 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 混合パロキセチンプロパン−２−オール溶媒和物
GB9826171D0 (en) * 1998-11-30 1999-01-20 Smithkline Beecham Plc Novel compounds
GB9828767D0 (en) * 1998-12-29 1999-02-17 Smithkline Beecham Plc Novel process
EP1161241B1 (de) * 1999-03-12 2005-12-07 Aesica Pharmaceuticals Ltd. Stabile pharmazeutische anwendungsform für paroxetin-anhydrat
GB9914583D0 (en) * 1999-06-22 1999-08-25 Smithkline Beecham Plc Novel process
GB9914585D0 (en) * 1999-06-22 1999-08-25 Smithkline Beecham Plc Novel process
GB9919001D0 (en) * 1999-08-12 1999-10-13 Smithkline Beecham Plc Novel process
GB9923439D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
GB9923445D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
GB9923446D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
HU226912B1 (en) * 2000-04-07 2010-03-01 Richter Gedeon Nyrt New paroxetin salt and medicament containing it
WO2002022609A1 (fr) * 2000-09-14 2002-03-21 Asahi Glass Company, Limited Procede de production de sel de paroxetine sensiblement exempt de solvant organique
AU2002259114A1 (en) * 2002-02-22 2003-09-09 Teva Pharmaceutical Industries Ltd. Preparation of paroxetine involving novel intermediates
KR20080055990A (ko) * 2005-11-22 2008-06-19 테바 파마슈티컬 인더스트리즈 리미티드 시나칼셋 ＨＣｌ의 결정형 및 이의 제조 방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1422263A (en) * 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds
GB8430581D0 (en) * 1984-12-04 1985-01-09 Ferrosan As Treatment
ES2058061T3 (es) * 1985-10-25 1994-11-01 Beecham Group Plc Derivado de piperidina, su preparacion y su uso como medicamento.
GB8626936D0 (en) * 1986-11-11 1986-12-10 Ferrosan As Treatment
DK716088D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Reduktion af piperidin-dion-derivater samt intermediat
DK715988D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Etherifikation og dealkylering af piperidin-derivater samt intermediater
US5371092A (en) * 1990-11-24 1994-12-06 Beecham Group, P.L.C. Use of paroxetine for the treatment of senile dementia, bulimia, migraine or anorexia
GB9325644D0 (en) * 1993-12-15 1994-02-16 Smithkline Beecham Plc Novel formulation

Also Published As

Publication number Publication date
CZ297171B6 (cs) 2006-09-13
CA2211522A1 (en) 1996-08-07
SI9600036A (en) 1996-10-31
IT1289532B1 (it) 1998-10-15
FI20030162A (fi) 2003-02-03
IL117035A (en) 2000-02-29
ITMI960203A0 (ja) 1996-02-05
NO20015070D0 (no) 2001-10-18
SK14396A3 (en) 1996-11-06
CA2210022C (en) 2005-09-13
BG100333A (bg) 1996-08-30
RU2125052C1 (ru) 1999-01-20
TR199600096A2 (tr) 1996-08-21
NO301009B3 (ja) 2003-01-06
SI21923A (sl) 2006-06-30
MC2411A1 (fr) 1996-12-02
PL312646A1 (en) 1996-08-19
CA2168829A1 (en) 1996-08-07
ES2114471A1 (es) 1998-05-16
EP1378508A1 (en) 2004-01-07
MX9600484A (es) 1997-01-31
AR036856A2 (es) 2004-10-06
IE960104A1 (en) 1996-08-07
HUP9600255A1 (en) 1997-03-28
EP1136490B1 (en) 2004-01-07
ES2114471B1 (es) 1999-08-16
IE80500B1 (en) 1998-08-12
JPH11228571A (ja) 1999-08-24
MA23802A1 (fr) 1996-10-01
DE19603797C2 (de) 1998-11-12
BG62967B1 (bg) 2000-12-29
AU4786496A (en) 1996-08-27
CN1143643A (zh) 1997-02-26
CN1636993A (zh) 2005-07-13
CA2210023C (en) 1999-02-09
EP0808314A1 (en) 1997-11-26
PT101827A (pt) 1996-09-30
FI20030370A (fi) 2003-03-12
FR2730232A1 (fr) 1996-08-09
FR2730232B1 (fr) 1997-08-01
NL1002248A1 (nl) 1996-08-06
AU701518C (en) 2006-12-07
NZ280943A (en) 1997-01-29
DE19603797A1 (de) 1996-08-14
LV11618A (lv) 1996-12-20
CA2211522C (en) 1999-12-07
ATA21096A (de) 2000-08-15
FI960519A (fi) 1996-08-07
SI21923B (sl) 2006-12-31
PL189247B1 (pl) 2005-07-29
CH689229A5 (de) 1998-12-31
SG43787A1 (en) 1997-11-14
KR960031409A (ko) 1996-09-17
NO311519B1 (no) 2001-12-03
DK11996A (da) 1996-08-07
DZ1989A1 (fr) 2002-10-15
AU4332896A (en) 1996-08-15
AT407528B (de) 2001-04-25
CH689804A5 (de) 1999-11-30
CZ32096A3 (en) 1996-08-14
OA10261A (en) 1997-09-19
CN1090187C (zh) 2002-09-04
FI111544B (fi) 2003-08-15
DK200100223A (ja) 2001-02-12
SK283608B6 (sk) 2003-10-07
BR9600534A (pt) 1997-05-13
JP2915338B2 (ja) 1999-07-05
CA2210023A1 (en) 1996-08-07
SE521084C2 (sv) 2003-09-30
UA49796C2 (uk) 2002-10-15
SE9600406D0 (sv) 1996-02-05
MX198371B (ja) 2000-08-29
EP0808314B1 (en) 2002-06-12
LV11618B (en) 1997-04-20
CN1289496C (zh) 2006-12-13
NO970939L (no) 1996-08-07
SE9600406L (sv) 1996-08-07
CN1310180A (zh) 2001-08-29
TW503238B (en) 2002-09-21
KR100289885B1 (ko) 2001-05-15
PT101827B (pt) 1997-08-29
DE69621777D1 (de) 2002-07-18
LU88711A1 (fr) 1996-08-23
SI9600036B (sl) 2006-12-31
DE69631298D1 (de) 2004-02-12
NO960472L (no) 1996-08-07
CA2210022A1 (en) 1996-08-07
NO20015070L (no) 1996-08-07
HU9600255D0 (en) 1996-03-28
FI960519A0 (fi) 1996-02-05
AR001982A1 (es) 1998-01-07
CN1216055C (zh) 2005-08-24
NO970939D0 (no) 1997-02-28
EP1136490A1 (en) 2001-09-26
GR1002466B (el) 1996-11-06
DE69631298T2 (de) 2004-11-18
NL1002248C2 (nl) 1996-09-11
DE69621777T2 (de) 2003-01-02
NO960472D0 (no) 1996-02-05
JPH08245620A (ja) 1996-09-24
WO1996024595A1 (en) 1996-08-15
MY132529A (en) 2007-10-31
BE1009112A3 (fr) 1996-11-05
CH688353A5 (de) 1997-08-15
NO301009B1 (no) 1997-09-01
ITMI960203A1 (it) 1997-08-05
RO112426B1 (ro) 1997-09-30
AU701518B2 (en) 1999-01-28
IL117035A0 (en) 1996-09-12
CA2168829C (en) 1997-12-16

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20130131