HK1251457A1 - Methods for making dpa-enriched compositions of omega-3 polyunsaturated fatty acids in free acid form - Google Patents

Methods for making dpa-enriched compositions of omega-3 polyunsaturated fatty acids in free acid form Download PDF

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Publication number
HK1251457A1
HK1251457A1 HK18110835.8A HK18110835A HK1251457A1 HK 1251457 A1 HK1251457 A1 HK 1251457A1 HK 18110835 A HK18110835 A HK 18110835A HK 1251457 A1 HK1251457 A1 HK 1251457A1
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HK
Hong Kong
Prior art keywords
amount
acid
epa
dpa
dha
Prior art date
Application number
HK18110835.8A
Other languages
English (en)
Chinese (zh)
Inventor
Timothy J Maines
Bernardus N M MACHIELSE
Bharat M Mehta
Gerald WISLER
Michael Davidson
Peter Ralph WOOD
Original Assignee
Omthera Pharmaceuticals Inc.
Chrysalis Pharma Ag
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48744082&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1251457(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Omthera Pharmaceuticals Inc., Chrysalis Pharma Ag filed Critical Omthera Pharmaceuticals Inc.
Publication of HK1251457A1 publication Critical patent/HK1251457A1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Materials For Photolithography (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK18110835.8A 2012-01-06 2015-03-17 Methods for making dpa-enriched compositions of omega-3 polyunsaturated fatty acids in free acid form HK1251457A1 (en)

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
US201261583796P 2012-01-06 2012-01-06
US201261583796P 2012-01-06
US201261664047P 2012-06-25 2012-06-25
US201261664047P 2012-06-25
US201261669940P 2012-07-10 2012-07-10
US201261669940P 2012-07-10
US201261680622P 2012-08-07 2012-08-07
US201261680622P 2012-08-07
US201261710517P 2012-10-05 2012-10-05
US201261710517P 2012-10-05
US201261713388P 2012-10-12 2012-10-12
US201261713388P 2012-10-12

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
HK15102685.9A Addition HK1202073B (en) 2012-01-06 2013-01-04 Dpa-enriched compositions of omega-3 polyunsaturated fatty acids in free acid form

Related Child Applications (1)

Application Number Title Priority Date Filing Date
HK15102685.9A Division HK1202073B (en) 2012-01-06 2013-01-04 Dpa-enriched compositions of omega-3 polyunsaturated fatty acids in free acid form

Publications (1)

Publication Number Publication Date
HK1251457A1 true HK1251457A1 (en) 2019-02-01

Family

ID=48744082

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Application Number Title Priority Date Filing Date
HK18110835.8A HK1251457A1 (en) 2012-01-06 2015-03-17 Methods for making dpa-enriched compositions of omega-3 polyunsaturated fatty acids in free acid form

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US (5) US20150004224A1 (enExample)
EP (2) EP2800563B1 (enExample)
JP (3) JP6399655B2 (enExample)
KR (2) KR102153245B1 (enExample)
CN (3) CN104321055A (enExample)
BR (1) BR112014016788A8 (enExample)
CA (1) CA2860512C (enExample)
CL (1) CL2014001803A1 (enExample)
CO (1) CO7061070A2 (enExample)
CY (1) CY1120663T1 (enExample)
DK (1) DK2800563T3 (enExample)
DO (1) DOP2014000159A (enExample)
EC (1) ECSP14012527A (enExample)
ES (1) ES2685703T3 (enExample)
HK (1) HK1251457A1 (enExample)
HR (1) HRP20181418T1 (enExample)
HU (1) HUE039659T2 (enExample)
IL (3) IL233517A (enExample)
IN (1) IN2014DN06125A (enExample)
LT (1) LT2800563T (enExample)
MX (1) MX358319B (enExample)
MY (1) MY165048A (enExample)
NZ (1) NZ626699A (enExample)
PE (1) PE20142459A1 (enExample)
PH (2) PH12014501553A1 (enExample)
PL (1) PL2800563T3 (enExample)
PT (1) PT2800563T (enExample)
RS (1) RS57777B1 (enExample)
RU (2) RU2664429C2 (enExample)
SG (2) SG10201701004RA (enExample)
SI (1) SI2800563T1 (enExample)
SM (1) SMT201800519T1 (enExample)
UA (1) UA114615C2 (enExample)
WO (1) WO2013103902A1 (enExample)
ZA (1) ZA201405765B (enExample)

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