JPS5735512A - Preventive and remedy for thrombosis - Google Patents
Preventive and remedy for thrombosisInfo
- Publication number
- JPS5735512A JPS5735512A JP8807280A JP8807280A JPS5735512A JP S5735512 A JPS5735512 A JP S5735512A JP 8807280 A JP8807280 A JP 8807280A JP 8807280 A JP8807280 A JP 8807280A JP S5735512 A JPS5735512 A JP S5735512A
- Authority
- JP
- Japan
- Prior art keywords
- remedy
- thrombosis
- preventive
- long period
- active component
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
- C07C57/03—Monocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Abstract
PURPOSE: To provide a preventive and remedy for thrombosis, capable of inhibiting the coagulation of blood platelet and dissolving the coagulated blood platelet, by using (all-Z)-4,7,10,13,16,19-docosahexanoic acid, etc. as active component.
CONSTITUTION: A preventive and remedy for thrombosis, having excellent for the prevention and remedy of deep phlebothrombosis, etc., and cardiac infarction, etc. caused thereby, can be obtained by using a compound selected from (all-Z)-4,7,10, 13,16,19-docosahexanoic acid, its pharmacologically permissible salt, ester, and amide as an active component. As the compound can be easily absorbed through the intestines, is orally administrable, and is stable in blood, it keeps the effect for a long period. Furthermore, it can be taken in a relatively high dose for a long period, without getting too fat by the excessive caloric intake. The above acid can be separated from aquatic animals by conventional process.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8807280A JPS5735512A (en) | 1980-06-27 | 1980-06-27 | Preventive and remedy for thrombosis |
PCT/JP1981/000148 WO1982000095A1 (en) | 1980-06-27 | 1981-06-27 | Thrombosis-prophylatic and curing agent |
GB8204905A GB2090529B (en) | 1980-06-27 | 1981-06-27 | Thrombosis-prophylactic and curing agent |
DE19813152174 DE3152174A1 (en) | 1980-06-27 | 1981-06-27 | THROMBOSIS-PROPHYLATIC AND CURING AGENT |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8807280A JPS5735512A (en) | 1980-06-27 | 1980-06-27 | Preventive and remedy for thrombosis |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5735512A true JPS5735512A (en) | 1982-02-26 |
JPH0141604B2 JPH0141604B2 (en) | 1989-09-06 |
Family
ID=13932644
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP8807280A Granted JPS5735512A (en) | 1980-06-27 | 1980-06-27 | Preventive and remedy for thrombosis |
Country Status (3)
Country | Link |
---|---|
JP (1) | JPS5735512A (en) |
GB (1) | GB2090529B (en) |
WO (1) | WO1982000095A1 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60237017A (en) * | 1984-05-09 | 1985-11-25 | Nippon Light Metal Co Ltd | Fat transfusion solution agent |
JPS60248610A (en) * | 1984-05-23 | 1985-12-09 | Nitsusui Seiyaku Kk | Preventive and remedy for complicated diabetes |
JPH0249723A (en) * | 1988-04-18 | 1990-02-20 | Taiyo Fishery Co Ltd | Encephalon function improving composition, learning ability enhancing agent, memory enhancing agent, preventive and remedy for dementia or functional food having encephalon function improving effect |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3307244A1 (en) * | 1982-08-06 | 1984-02-16 | Theodor 6450 Hanau Splithoff | Carrier preferably for holding a sign |
US4701469A (en) * | 1983-04-15 | 1987-10-20 | Roussel Uclaf | Triglycerides, process for therapeutical applications and compositions containing them |
US4607052A (en) * | 1983-04-15 | 1986-08-19 | Roussel-Uclaf | Triglycerides, dietetic and therapeutical applications and compositions containing them |
GB8603621D0 (en) * | 1986-02-14 | 1986-03-19 | Habib N | Modifying lipid structure of cell membranes |
DE3615710A1 (en) * | 1986-05-09 | 1987-11-26 | Hoechst Ag | PREPARATIONS FOR THE SYNTHESIS OF PROSTAGLANDINES AND HYDROXY FATTY ACIDS IN BIOLOGICAL SYSTEMS |
GB8729751D0 (en) * | 1987-12-21 | 1988-02-03 | Norsk Hydro As | Feed additive & feed containing such additive |
GB2218984B (en) * | 1988-05-27 | 1992-09-23 | Renafield Limited | Process for preparing high-concentration mixtures of polyunsaturated fatty acids & their esters and their prophylactic or therapeutic uses |
GB2218904A (en) * | 1988-05-27 | 1989-11-29 | Renafield Limited | Pharmaceutical composition based on high-concentration esters of docosahexaenoic acid |
GB8819110D0 (en) * | 1988-08-11 | 1988-09-14 | Norsk Hydro As | Antihypertensive drug & method for production |
GB2223943A (en) * | 1988-10-21 | 1990-04-25 | Tillotts Pharma Ag | Oral disage forms of omega-3 polyunsaturated acids |
FR2643637B1 (en) * | 1989-02-27 | 1991-09-20 | Natura Medica Laboratoires | CALCIUM ION COMPLEX WITH AT LEAST ONE UNSATURATED FATTY ACID, BIOMEDIATING AGENT COMPRISING SUCH A COMPLEX, PHARMACEUTICAL COMPOSITION INCORPORATING SAME AND PLANT OR ORGAN EXTRACTS CONTAINING THE SAME |
ITMI20010129A1 (en) | 2001-01-25 | 2002-07-25 | Pharmacia & Upjohn Spa | ESSENTIAL FATTY ACIDS IN THE THERAPY OF HEART INSUFFICIENCY AND HEART FAILURE |
GB0403247D0 (en) | 2004-02-13 | 2004-03-17 | Tillotts Pharma Ag | A pharmaceutical composition |
CA2860512C (en) | 2012-01-06 | 2019-02-05 | Omthera Pharmaceuticals, Inc. | Dpa-enriched compositions of omega-3 polyunsaturated fatty acids in free acid form |
JP6173437B2 (en) | 2012-05-07 | 2017-08-02 | オムセラ・ファーマシューティカルズ・インコーポレイテッド | Statins and omega-3 fatty acid compositions |
CN104958725A (en) * | 2015-07-05 | 2015-10-07 | 四川金堂海纳生物医药技术研究所 | Oral administration medicament for treating venous thrombosis and preparation method thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA784083B (en) * | 1978-05-26 | 1980-02-27 | Wellcome Found | Fatty acid and derivatives thereof,and formulations containing them for use in treatment or prophyllaxis of thrombo-embolic conditions |
AU527784B2 (en) * | 1978-05-26 | 1983-03-24 | Bang, Hans Olaf Dr. | Treatment of thromboembolic conditions withall-z)-5, 8, 11, 14, 17-eicosapentaenoic acid |
-
1980
- 1980-06-27 JP JP8807280A patent/JPS5735512A/en active Granted
-
1981
- 1981-06-27 WO PCT/JP1981/000148 patent/WO1982000095A1/en active Application Filing
- 1981-06-27 GB GB8204905A patent/GB2090529B/en not_active Expired
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60237017A (en) * | 1984-05-09 | 1985-11-25 | Nippon Light Metal Co Ltd | Fat transfusion solution agent |
JPS60248610A (en) * | 1984-05-23 | 1985-12-09 | Nitsusui Seiyaku Kk | Preventive and remedy for complicated diabetes |
JPH0249723A (en) * | 1988-04-18 | 1990-02-20 | Taiyo Fishery Co Ltd | Encephalon function improving composition, learning ability enhancing agent, memory enhancing agent, preventive and remedy for dementia or functional food having encephalon function improving effect |
Also Published As
Publication number | Publication date |
---|---|
GB2090529B (en) | 1985-04-24 |
JPH0141604B2 (en) | 1989-09-06 |
GB2090529A (en) | 1982-07-14 |
WO1982000095A1 (en) | 1982-01-21 |
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