JPS5661314A - Preventive against side-effect for dialytic patient - Google Patents

Preventive against side-effect for dialytic patient

Info

Publication number
JPS5661314A
JPS5661314A JP13803079A JP13803079A JPS5661314A JP S5661314 A JPS5661314 A JP S5661314A JP 13803079 A JP13803079 A JP 13803079A JP 13803079 A JP13803079 A JP 13803079A JP S5661314 A JPS5661314 A JP S5661314A
Authority
JP
Japan
Prior art keywords
preventive
carnitine
patient
dialytic
actions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP13803079A
Other languages
Japanese (ja)
Other versions
JPH0440328B2 (en
Inventor
Yuzo Kawashima
Yoshiroku Tomiyama
Noboru Yamazaki
Yoshikazu Suzuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to JP13803079A priority Critical patent/JPS5661314A/en
Publication of JPS5661314A publication Critical patent/JPS5661314A/en
Publication of JPH0440328B2 publication Critical patent/JPH0440328B2/ja
Granted legal-status Critical Current

Links

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PURPOSE: A preventive for a dialytic patient against side effects, e.g., disorder of blood vessel of heart, weaking of the whole body, etc., comprising carnitine or its salt.
CONSTITUTION: A preventive comprising a dl-, d-, or l-derivative of carnitine shown by the formula or their pharmaceutically acceptable salts as an active ingredient. When a patient of renopathy, etc. is subjected to dialysis continuously, harmful actions such as disorder of blood vessel of heart, e.g, arrhythmia, myocardial infraction, etc., weakening of the whole body, giddiness, headache, etc. occur. But the administration of carmitine is capable of preventing and remedying these harmful actions. The preventive is prescribed orally or parenterally. The reason is uncertain, but the fact that carnitine or its salt reduces a concentration of fatty acid in the blood and has actions to promote the absorption of long-chain Acyl- CoA to mitochondria membtane and to improve the energy metabolism of cardiac muscle is considered to be related to the reason.
COPYRIGHT: (C)1981,JPO&Japio
JP13803079A 1979-10-24 1979-10-24 Preventive against side-effect for dialytic patient Granted JPS5661314A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP13803079A JPS5661314A (en) 1979-10-24 1979-10-24 Preventive against side-effect for dialytic patient

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13803079A JPS5661314A (en) 1979-10-24 1979-10-24 Preventive against side-effect for dialytic patient

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2212937A Division JPH06102624B2 (en) 1990-08-10 1990-08-10 Anti-arrhythmic drugs of non-heart origin

Publications (2)

Publication Number Publication Date
JPS5661314A true JPS5661314A (en) 1981-05-26
JPH0440328B2 JPH0440328B2 (en) 1992-07-02

Family

ID=15212397

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13803079A Granted JPS5661314A (en) 1979-10-24 1979-10-24 Preventive against side-effect for dialytic patient

Country Status (1)

Country Link
JP (1) JPS5661314A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60156613A (en) * 1984-01-24 1985-08-16 Japan Hosupitaru Supply:Kk Preventive agent for dialysis shock
GB2230953A (en) * 1989-05-05 1990-11-07 Sigma Tau Ind Farmaceuti Compositions containing D-carnitine or an acyl derivative for the treatment of protozoal disease

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54151130A (en) * 1978-05-15 1979-11-28 Cavazza Claudio Treating agent for kidney disease

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54151130A (en) * 1978-05-15 1979-11-28 Cavazza Claudio Treating agent for kidney disease

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60156613A (en) * 1984-01-24 1985-08-16 Japan Hosupitaru Supply:Kk Preventive agent for dialysis shock
GB2230953A (en) * 1989-05-05 1990-11-07 Sigma Tau Ind Farmaceuti Compositions containing D-carnitine or an acyl derivative for the treatment of protozoal disease
GB2230953B (en) * 1989-05-05 1993-03-24 Sigma Tau Ind Farmaceuti Compositions containing d-carnitine or an acyl derivative for the treatment of protozoal disease

Also Published As

Publication number Publication date
JPH0440328B2 (en) 1992-07-02

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