JPS57128635A - Pharmaceutical preparation of gamma-globulin for venoclysis - Google Patents
Pharmaceutical preparation of gamma-globulin for venoclysisInfo
- Publication number
- JPS57128635A JPS57128635A JP1352181A JP1352181A JPS57128635A JP S57128635 A JPS57128635 A JP S57128635A JP 1352181 A JP1352181 A JP 1352181A JP 1352181 A JP1352181 A JP 1352181A JP S57128635 A JPS57128635 A JP S57128635A
- Authority
- JP
- Japan
- Prior art keywords
- globulin
- gamma
- venoclysis
- sufficiently low
- activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
PURPOSE: A pharmaceutical preparation of gamma-globulin for venoclysis being stable for a long time, useful for remedying and preventing various kinds of microbisms, comprising a gamma-globulin having a sufficiently low anticomplementary activity and sodium chloride and L-arginine or L-lysine in a specific ratio.
CONSTITUTION: 1pts.wt. gamma-globulin having sufficiently low anticomplementary activity is blended with 0.12W0.24pts.wt. sodium chloride and 0.69W1.04pts.wt. L-alignine or 0.58W0.88pts.wt. L-lysine, to give a gamma-globulin for venoclysis. Since a gamma-globulin so far obtained from plasma contains impurities exhibiting high anticomplementary activity, its use is limited to an intramuscular injection, but it has such defects that it has a pain of the affected part, and it is decomposed during its long retention time in the affected part so that sufficient concentration in the blood is not attained. The above-mentioned defects are eliminated by adding stabilizers nontoxic to a living body, exhibiting activity at a concentration close to a physiologic osmotic pressure to a gamma-globulin with its impurities removed, having sufficiently low anticomplementary activity.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1352181A JPS57128635A (en) | 1981-01-30 | 1981-01-30 | Pharmaceutical preparation of gamma-globulin for venoclysis |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1352181A JPS57128635A (en) | 1981-01-30 | 1981-01-30 | Pharmaceutical preparation of gamma-globulin for venoclysis |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57128635A true JPS57128635A (en) | 1982-08-10 |
Family
ID=11835452
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1352181A Pending JPS57128635A (en) | 1981-01-30 | 1981-01-30 | Pharmaceutical preparation of gamma-globulin for venoclysis |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57128635A (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011034604A2 (en) | 2009-09-17 | 2011-03-24 | Baxter Healthcare, S.A. | Stable co-formulation of hyaluronidase and immunoglobulin, and methods of use thereof |
US8906368B2 (en) | 2003-11-18 | 2014-12-09 | Zlb Behring Ag | Immunoglobulin preparations having increased stability |
US9241897B2 (en) | 2010-02-04 | 2016-01-26 | Csl Behring Ag | Immunoglobulin preparation |
US9422364B2 (en) | 2010-02-26 | 2016-08-23 | Csl Behring Ag | Immunoglobulin preparation and storage system for an immunoglobulin preparation |
US10301376B2 (en) | 2008-03-17 | 2019-05-28 | Baxalta GmbH | Combinations and methods for subcutaneous administration of immune globulin and hyaluronidase |
-
1981
- 1981-01-30 JP JP1352181A patent/JPS57128635A/en active Pending
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8906368B2 (en) | 2003-11-18 | 2014-12-09 | Zlb Behring Ag | Immunoglobulin preparations having increased stability |
US10301376B2 (en) | 2008-03-17 | 2019-05-28 | Baxalta GmbH | Combinations and methods for subcutaneous administration of immune globulin and hyaluronidase |
USRE49967E1 (en) | 2008-03-17 | 2024-05-14 | Takeda Pharmaceutical Company Limited | Combinations and methods for subcutaneous administration of immune globulin and hyaluronidase |
WO2011034604A2 (en) | 2009-09-17 | 2011-03-24 | Baxter Healthcare, S.A. | Stable co-formulation of hyaluronidase and immunoglobulin, and methods of use thereof |
US9084743B2 (en) | 2009-09-17 | 2015-07-21 | Baxter International Inc. | Stable co-formulation of hyaluronidase and immunoglobulin, and methods of use thereof |
US9241897B2 (en) | 2010-02-04 | 2016-01-26 | Csl Behring Ag | Immunoglobulin preparation |
US10137197B2 (en) | 2010-02-04 | 2018-11-27 | Csl Behring Ag | Process for preparing an immunoglobulin preparation |
US9422364B2 (en) | 2010-02-26 | 2016-08-23 | Csl Behring Ag | Immunoglobulin preparation and storage system for an immunoglobulin preparation |
US10434176B2 (en) | 2010-02-26 | 2019-10-08 | Csl Behring Ag | Immunoglobulin preparation and storage system for an immunoglobulin preparation |
US11419936B2 (en) | 2010-02-26 | 2022-08-23 | Csl Behring Ag | Immunoglobulin preparation and storage system for an immunoglobulin preparation |
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