JPS52139713A - Sustained release cefalexin preparations - Google Patents

Sustained release cefalexin preparations

Info

Publication number
JPS52139713A
JPS52139713A JP5492576A JP5492576A JPS52139713A JP S52139713 A JPS52139713 A JP S52139713A JP 5492576 A JP5492576 A JP 5492576A JP 5492576 A JP5492576 A JP 5492576A JP S52139713 A JPS52139713 A JP S52139713A
Authority
JP
Grant status
Application
Patent type
Prior art keywords
cefalexin
sustained release
preparations
preparation
japio
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP5492576A
Other versions
JPS5547611B2 (en )
Inventor
Hiroshi Kato
Hideyuki Maekawa
Yasushi Takagishi
Original Assignee
Shionogi & Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine

Abstract

PURPOSE: Sustained release cefalexin preparation comprising a combination of its rapid-dissolving preparation with its enteric preparation, which is maintained at high concentration in the blood for a long time with administration of longer intervals.
COPYRIGHT: (C)1977,JPO&Japio
JP5492576A 1976-05-13 1976-05-13 Expired JPS5547611B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP5492576A JPS5547611B2 (en) 1976-05-13 1976-05-13

Applications Claiming Priority (27)

Application Number Priority Date Filing Date Title
JP5492576A JPS5547611B2 (en) 1976-05-13 1976-05-13
CA 276514 CA1085296A (en) 1976-05-13 1977-04-20 Long acting preparation of cefalexin for effective treatments of bacterial infection sensitive to cefalexin
NZ18392777A NZ183927A (en) 1976-05-13 1977-04-26 Long-acting cefalexin preparation
NL7704879A NL7704879A (en) 1976-05-13 1977-05-03 Long acting cefalexinepreparaat.
PT6651477A PT66514B (en) 1976-05-13 1977-05-05 Process for long acting preparation of cefalexin for effective treatments of bacterial infections sensitive to cefalexin
ZA7702757A ZA7702757B (en) 1976-05-13 1977-05-09 Long acting preparation of cefalexin for effective treatments of bacterial infection sensitive to cefalexin
IE94077A IE45415B1 (en) 1976-05-13 1977-05-09 Long acting preparation of cefalexin
ES458710A ES458710A1 (en) 1976-05-13 1977-05-11 A method for obtaining a preparation of cephalexin deaccion prolonged.
FI771491A FI771491A (en) 1976-05-13 1977-05-11
SE7705502A SE426780B (en) 1976-05-13 1977-05-11 Process for the production tell up of a cefalexin
AU2507877A AU508793B2 (en) 1976-05-13 1977-05-11 Long acting preparation of cefalexin for effective treatmentsof bacterial infection sensitive to cefalexin
GB1985377A GB1543543A (en) 1976-05-13 1977-05-11 Long acting preparation of cefalexin
DK208077A DK208077A (en) 1976-05-13 1977-05-11 Cefalexinpreparat
PL19805877A PL111183B1 (en) 1976-05-13 1977-05-12 Method of obtaining a cephaloxine preparation
MX573977U MX5976E (en) 1976-05-13 1977-05-12 Improved process for preparing a pharmaceutical composition from cephalexin
SU2485596A SU1218919A3 (en) 1976-05-13 1977-05-12 Method of producing cephalexin of prolonged action for peroral application
RO9031277A RO72935A (en) 1976-05-13 1977-05-12 The process of obtaining a long-acting cephalexin preparation for oral administration in human medicine
HU184196B HU184196B (en) 1976-05-13 1977-05-12 Process for producing preparation containing 7-/d-2-amino-2-phenylacetamino/-3-methyl-3-cephem-4-carboxylic acid monohydrate
GR770153444A GR68895B (en) 1976-05-13 1977-05-12
FR7714616A FR2350836B1 (en) 1976-05-13 1977-05-12
AT341877A AT351159B (en) 1976-05-13 1977-05-12 A method for making a preparation with cephalexin- partially delayed active ingredient delivery for oral administration to humans
IL5207577A IL52075A (en) 1976-05-13 1977-05-12 Long acting preparation of cefalexin for effective treatments of bacterial infection sensitive to cefalexin
DE19772721785 DE2721785C2 (en) 1976-05-13 1977-05-13
CS316777A CS208196B2 (en) 1976-05-13 1977-05-13 Method of making the perorally applicable preparation with the retarded liberation of the cefalexine as the active component
AR26762177A AR224494A1 (en) 1976-05-13 1977-05-13 A process for preparing long-acting cephalexin
BE177585A BE854640A (en) 1976-05-13 1977-05-13 cefalexin preparation of a prolonged work for the effective treatment of infections by bacteria susceptible to cefalexin
DD19892277A DD132232A5 (en) 1976-05-13 1977-05-13 A process for the manufacture of an orally verabfolgbaren cephalexinpraeparates sustained-release

Publications (2)

Publication Number Publication Date
JPS52139713A true true JPS52139713A (en) 1977-11-21
JPS5547611B2 JPS5547611B2 (en) 1980-12-01

Family

ID=12984185

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5492576A Expired JPS5547611B2 (en) 1976-05-13 1976-05-13

Country Status (10)

Country Link
JP (1) JPS5547611B2 (en)
BE (1) BE854640A (en)
CA (1) CA1085296A (en)
DE (1) DE2721785C2 (en)
DK (1) DK208077A (en)
ES (1) ES458710A1 (en)
FI (1) FI771491A (en)
FR (1) FR2350836B1 (en)
GB (1) GB1543543A (en)
NL (1) NL7704879A (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5545601A (en) * 1978-09-26 1980-03-31 Toyo Jozo Co Ltd Long-acting cephalexin and its preparation
JPS5659707A (en) * 1979-10-19 1981-05-23 Toyo Jozo Co Ltd Lasting antibiotic pharmaceutical and its preparation
JPS5883613A (en) * 1981-11-10 1983-05-19 Toa Eiyou Kagaku Kogyo Kk Isosorbitol nitrate pharmaceutical
JPS5883106U (en) * 1981-11-30 1983-06-06
JPS601128A (en) * 1983-06-15 1985-01-07 Shionogi & Co Ltd Long-acting cefaclor preparation
JPS6144811A (en) * 1984-08-10 1986-03-04 Ss Pharmaceut Co Ltd Sustained release diclofenac sodium pharmaceutical
JPS62226926A (en) * 1986-03-27 1987-10-05 Teisan Seiyaku Kk Long acting complex granule
JP2008535922A (en) * 2005-04-12 2008-09-04 エラン・ファルマ・インターナショナル・リミテッド Controlled release compositions comprising a cephalosporin to treat bacterial infections

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2453639B1 (en) * 1979-04-09 1982-03-19 Sanofi Sa
JPS5826816A (en) * 1981-08-11 1983-02-17 Teisan Seiyaku Kk Compounded granule having prolonged effect consisting of spherical granule
JPH0122245B2 (en) * 1981-09-14 1989-04-25 Kanebo Ltd
US4525339A (en) * 1982-10-15 1985-06-25 Hoffmann-La Roche Inc. Enteric coated oral dosage form
FR2577800B1 (en) * 1985-02-22 1990-09-07 Grimberg Georges Medicament form GALENICAL gastro-resistant

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
THE JAPANESE JOURNAL OF ANTIBIOTICS=1969 *

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5545601A (en) * 1978-09-26 1980-03-31 Toyo Jozo Co Ltd Long-acting cephalexin and its preparation
JPS6213324B2 (en) * 1978-09-26 1987-03-25 Toyo Jozo Kk
JPS5659707A (en) * 1979-10-19 1981-05-23 Toyo Jozo Co Ltd Lasting antibiotic pharmaceutical and its preparation
JPS5883613A (en) * 1981-11-10 1983-05-19 Toa Eiyou Kagaku Kogyo Kk Isosorbitol nitrate pharmaceutical
JPS6133007B2 (en) * 1981-11-10 1986-07-31 Tooa Eiyoo Kk
JPS5883106U (en) * 1981-11-30 1983-06-06
JPS601128A (en) * 1983-06-15 1985-01-07 Shionogi & Co Ltd Long-acting cefaclor preparation
JPS6232166B2 (en) * 1983-06-15 1987-07-13 Shionogi & Co
JPS6144811A (en) * 1984-08-10 1986-03-04 Ss Pharmaceut Co Ltd Sustained release diclofenac sodium pharmaceutical
JPH0157090B2 (en) * 1984-08-10 1989-12-04 Ss Pharmaceutical Co
JPS62226926A (en) * 1986-03-27 1987-10-05 Teisan Seiyaku Kk Long acting complex granule
JP2008535922A (en) * 2005-04-12 2008-09-04 エラン・ファルマ・インターナショナル・リミテッド Controlled release compositions comprising a cephalosporin to treat bacterial infections

Also Published As

Publication number Publication date Type
BE854640A1 (en) grant
FR2350836B1 (en) 1981-02-06 grant
CA1085296A (en) 1980-09-09 grant
FI771491A (en) 1977-11-14 application
DE2721785A1 (en) 1977-11-24 application
ES458710A1 (en) 1978-03-01 application
BE854640A (en) 1977-09-01 grant
CA1085296A1 (en) grant
GB1543543A (en) 1979-04-04 application
FR2350836A1 (en) 1977-12-09 application
DE2721785C2 (en) 1989-03-16 grant
JPS5547611B2 (en) 1980-12-01 grant
DK208077A (en) 1977-11-14 application
NL7704879A (en) 1977-11-15 application

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