JPS57212117A - Intracranial pressure lowering agent - Google Patents

Intracranial pressure lowering agent

Info

Publication number
JPS57212117A
JPS57212117A JP56097296A JP9729681A JPS57212117A JP S57212117 A JPS57212117 A JP S57212117A JP 56097296 A JP56097296 A JP 56097296A JP 9729681 A JP9729681 A JP 9729681A JP S57212117 A JPS57212117 A JP S57212117A
Authority
JP
Japan
Prior art keywords
compound
intracranial pressure
sucrose
syrup
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP56097296A
Other languages
Japanese (ja)
Inventor
Masayoshi Samejima
Masaki Yoshida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Priority to JP56097296A priority Critical patent/JPS57212117A/en
Publication of JPS57212117A publication Critical patent/JPS57212117A/en
Pending legal-status Critical Current

Links

Abstract

PURPOSE: To provide the titled remedy free from side effects such as abnormality in the state of the blood, and composed of a syrup containing a propanol derivative or its acid addition salt, sucrose, and water.
CONSTITUTION: The compound of formulaI(R is lower alkyl; the ring A is phenyl, halogenophenyl, methylphenyl, or trifluoromethylphenyl) or its acid addition salt is dissolved in an aqueous solution of sucrose at a concentration of 0.0004W0.6w/v%, and if necessary, sterilized with heat and filtered to obtain the objective agent for depressing the intracranial pressure. The concentration of sucrose in the syrup is 15W60w/v%, and the pH of the syrup is preferably 3W 7. Dose: 1W10mg/kg daily. The compound of formula can be prepared by reacting the compound of formula II with the compound of formula III.
EFFECT: It is effective at an extremely low dose; keeps the activity for a long period, and is free of side effects such as the rebound of the intracranial pressure.
COPYRIGHT: (C)1982,JPO&Japio
JP56097296A 1981-06-22 1981-06-22 Intracranial pressure lowering agent Pending JPS57212117A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP56097296A JPS57212117A (en) 1981-06-22 1981-06-22 Intracranial pressure lowering agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56097296A JPS57212117A (en) 1981-06-22 1981-06-22 Intracranial pressure lowering agent

Publications (1)

Publication Number Publication Date
JPS57212117A true JPS57212117A (en) 1982-12-27

Family

ID=14188527

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56097296A Pending JPS57212117A (en) 1981-06-22 1981-06-22 Intracranial pressure lowering agent

Country Status (1)

Country Link
JP (1) JPS57212117A (en)

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