JPS57212117A - Intracranial pressure lowering agent - Google Patents
Intracranial pressure lowering agentInfo
- Publication number
- JPS57212117A JPS57212117A JP56097296A JP9729681A JPS57212117A JP S57212117 A JPS57212117 A JP S57212117A JP 56097296 A JP56097296 A JP 56097296A JP 9729681 A JP9729681 A JP 9729681A JP S57212117 A JPS57212117 A JP S57212117A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- intracranial pressure
- sucrose
- syrup
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
PURPOSE: To provide the titled remedy free from side effects such as abnormality in the state of the blood, and composed of a syrup containing a propanol derivative or its acid addition salt, sucrose, and water.
CONSTITUTION: The compound of formulaI(R is lower alkyl; the ring A is phenyl, halogenophenyl, methylphenyl, or trifluoromethylphenyl) or its acid addition salt is dissolved in an aqueous solution of sucrose at a concentration of 0.0004W0.6w/v%, and if necessary, sterilized with heat and filtered to obtain the objective agent for depressing the intracranial pressure. The concentration of sucrose in the syrup is 15W60w/v%, and the pH of the syrup is preferably 3W 7. Dose: 1W10mg/kg daily. The compound of formula can be prepared by reacting the compound of formula II with the compound of formula III.
EFFECT: It is effective at an extremely low dose; keeps the activity for a long period, and is free of side effects such as the rebound of the intracranial pressure.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56097296A JPS57212117A (en) | 1981-06-22 | 1981-06-22 | Intracranial pressure lowering agent |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56097296A JPS57212117A (en) | 1981-06-22 | 1981-06-22 | Intracranial pressure lowering agent |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57212117A true JPS57212117A (en) | 1982-12-27 |
Family
ID=14188527
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56097296A Pending JPS57212117A (en) | 1981-06-22 | 1981-06-22 | Intracranial pressure lowering agent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57212117A (en) |
-
1981
- 1981-06-22 JP JP56097296A patent/JPS57212117A/en active Pending
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