JPS5721320A - Blood sugar level depressing agent - Google Patents

Blood sugar level depressing agent

Info

Publication number
JPS5721320A
JPS5721320A JP9385380A JP9385380A JPS5721320A JP S5721320 A JPS5721320 A JP S5721320A JP 9385380 A JP9385380 A JP 9385380A JP 9385380 A JP9385380 A JP 9385380A JP S5721320 A JPS5721320 A JP S5721320A
Authority
JP
Japan
Prior art keywords
blood sugar
sugar level
compound
formula
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP9385380A
Other languages
Japanese (ja)
Inventor
Narimitsu Honda
Hideaki Nagai
Yoshikazu Hinohara
Masuo Koizumi
Yasushi Murakami
Hideki Nakano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Priority to JP9385380A priority Critical patent/JPS5721320A/en
Publication of JPS5721320A publication Critical patent/JPS5721320A/en
Pending legal-status Critical Current

Links

Abstract

PURPOSE: To provide a blood sugar level depressing agent containing a specific benzamide derivative as an active component.
CONSTITUTION: An agent containing the compound of formula [R1 and R2 are H, alkyl, (substituted) aralkyl, or (substituted) phenyl] as an active component. The compound of formula has excellent insulin biosynthesis promoting activity and blood sugar level depressing activity. It is effective at a dose of 0.lW100mg/kg for man, and maintains the activity for ≥24hr by the administration of 0.1W100mg/kg, once a day. The compound of formula can be prepared easily e.g. by reducing the corresponding m-nitrobenzoic acid amide by conventional method.
COPYRIGHT: (C)1982,JPO&Japio
JP9385380A 1980-07-11 1980-07-11 Blood sugar level depressing agent Pending JPS5721320A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP9385380A JPS5721320A (en) 1980-07-11 1980-07-11 Blood sugar level depressing agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9385380A JPS5721320A (en) 1980-07-11 1980-07-11 Blood sugar level depressing agent

Publications (1)

Publication Number Publication Date
JPS5721320A true JPS5721320A (en) 1982-02-04

Family

ID=14093968

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9385380A Pending JPS5721320A (en) 1980-07-11 1980-07-11 Blood sugar level depressing agent

Country Status (1)

Country Link
JP (1) JPS5721320A (en)

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3305755A1 (en) * 1983-02-19 1984-08-23 Gödecke AG, 1000 Berlin N-PHENYL-BENZAMIDE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN THE FIGHT AGAINST DISEASES OF THE IMMUNE SYSTEM
WO1996031462A1 (en) * 1995-04-03 1996-10-10 Centaur Pharmaceuticals, Inc. Benzamides for neurodegenerative disorder treatment
US5914350A (en) * 1995-04-03 1999-06-22 Centaur Pharmaceuticals, Inc. Pharmaceutical compositions of nitro- and aminobenzamide compounds for neurodegenerative disorders
US5955506A (en) * 1996-04-03 1999-09-21 Centaur Pharmaceuticals, Inc. Benzamides for neurodegenerative disorder treatment
GB2316403B (en) * 1996-08-17 2000-04-26 Ciba Sc Holding Ag Process
US6509378B2 (en) 1995-04-03 2003-01-21 Centaur Pharmaceuticals, Inc. Acetamidobenzamide compounds for neurodegenerative disorders
EP1500643A4 (en) * 2002-04-03 2007-03-28 Dainippon Sumitomo Pharma Co Benzamide derivatives
US7199140B2 (en) 2001-06-26 2007-04-03 Astrazeneca Ab Vinyl phenyl derivatives as GLK activators
US7524957B2 (en) 2001-08-17 2009-04-28 Astrazeneca Ab Compounds effecting glucokinase
US7642259B2 (en) 2005-07-09 2010-01-05 Astrazeneca Ab Heteroaryl benzamide derivatives for use as GLK activators in the treatment of diabetes
US7696191B2 (en) 2006-12-21 2010-04-13 Astrazeneca Ab Crystalline compound
US7700640B2 (en) 2004-10-16 2010-04-20 Astrazeneca Ab Process for making phenoxy benzamide compounds
US7709505B2 (en) 2002-11-19 2010-05-04 Astrazeneca Ab Benzofuran derivatives, process for their preparation and intermediates thereof
US7902200B2 (en) 2006-10-23 2011-03-08 Astrazeneca Ab Chemical compounds
US7973178B2 (en) 2005-11-28 2011-07-05 Astrazeneca Ab Chemical process for the preparation of an amido-phenoxybenzoic acid compound
US8071608B2 (en) 2009-04-09 2011-12-06 Astrazeneca Ab Therapeutic agents
US10548911B2 (en) 2014-06-16 2020-02-04 University Of Rochester Small molecule anti-scarring agents

Cited By (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3305755A1 (en) * 1983-02-19 1984-08-23 Gödecke AG, 1000 Berlin N-PHENYL-BENZAMIDE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN THE FIGHT AGAINST DISEASES OF THE IMMUNE SYSTEM
US4816485A (en) * 1983-02-19 1989-03-28 Warner-Lambert Company N-phenylbenzamide derivatives
US4857662A (en) * 1983-02-19 1989-08-15 Godecke Aktiengesellschaft N-phenylbenzamide derivatives
WO1996031462A1 (en) * 1995-04-03 1996-10-10 Centaur Pharmaceuticals, Inc. Benzamides for neurodegenerative disorder treatment
US5914350A (en) * 1995-04-03 1999-06-22 Centaur Pharmaceuticals, Inc. Pharmaceutical compositions of nitro- and aminobenzamide compounds for neurodegenerative disorders
AU721045B2 (en) * 1995-04-03 2000-06-22 Renovis, Inc. Benzamides for neurodegenerative disorder treatment
US6509378B2 (en) 1995-04-03 2003-01-21 Centaur Pharmaceuticals, Inc. Acetamidobenzamide compounds for neurodegenerative disorders
US6759433B2 (en) 1995-04-03 2004-07-06 Renovis, Inc. Acetamidobenzamide compounds for neurodegenerative disorders
US7005546B2 (en) 1995-04-03 2006-02-28 Renovis, Inc. Acetamidobenzamide compounds for neurodegenerative disorders
US5955506A (en) * 1996-04-03 1999-09-21 Centaur Pharmaceuticals, Inc. Benzamides for neurodegenerative disorder treatment
GB2316403B (en) * 1996-08-17 2000-04-26 Ciba Sc Holding Ag Process
US7199140B2 (en) 2001-06-26 2007-04-03 Astrazeneca Ab Vinyl phenyl derivatives as GLK activators
US7524957B2 (en) 2001-08-17 2009-04-28 Astrazeneca Ab Compounds effecting glucokinase
US7951830B2 (en) 2001-08-17 2011-05-31 Astrazeneca Ab Compounds effecting glucokinase
EP1500643A4 (en) * 2002-04-03 2007-03-28 Dainippon Sumitomo Pharma Co Benzamide derivatives
US7709505B2 (en) 2002-11-19 2010-05-04 Astrazeneca Ab Benzofuran derivatives, process for their preparation and intermediates thereof
US7700640B2 (en) 2004-10-16 2010-04-20 Astrazeneca Ab Process for making phenoxy benzamide compounds
US7642263B2 (en) 2005-07-09 2010-01-05 Astrazeneca Ab Heteroaryl benzamide derivatives for use as GLK activators in the treatment of diabetes
US7642259B2 (en) 2005-07-09 2010-01-05 Astrazeneca Ab Heteroaryl benzamide derivatives for use as GLK activators in the treatment of diabetes
US7977328B2 (en) 2005-07-09 2011-07-12 Astrazeneca Ab Heteroaryl benzamide derivatives for use as GLK activators in the treatment of diabetes
US7973178B2 (en) 2005-11-28 2011-07-05 Astrazeneca Ab Chemical process for the preparation of an amido-phenoxybenzoic acid compound
US7902200B2 (en) 2006-10-23 2011-03-08 Astrazeneca Ab Chemical compounds
US7696191B2 (en) 2006-12-21 2010-04-13 Astrazeneca Ab Crystalline compound
US8071608B2 (en) 2009-04-09 2011-12-06 Astrazeneca Ab Therapeutic agents
US10548911B2 (en) 2014-06-16 2020-02-04 University Of Rochester Small molecule anti-scarring agents

Similar Documents

Publication Publication Date Title
JPS5721320A (en) Blood sugar level depressing agent
ES8100249A1 (en) Novel hydroxamic acid compounds, method for preparation thereof and medicaments containing such compounds
IE821108L (en) Pyrazoline derivatives.
ES8407009A1 (en) (-)-15-Deoxyspergualin, a process for the preparation of the same, and a pharmaceutical composition containing the same.
JPS57140754A (en) Dihydroxybenzoic acid derivative and physiologically active preparation containing the same
JPS5740408A (en) Hypoglycemic
JPS5668612A (en) Novel antiallergic agent
JPS57131719A (en) Blood sugar level lowering agent
JPS5395912A (en) New derivative of active acetic acid ulceratives
IE820914L (en) Controlling ureaplasma infections
JPS5731616A (en) Relaxing agent for muscle comprising benzofurancarboxylic acid amide
EP0177463A3 (en) Derivatives of 2-amino-thiazole having an acid secretion inhibiting activity
JPS57136519A (en) Antidiabetic containing aminobenzoic acid derivative
JPS5569512A (en) Antispasmodic agent
JPS5772913A (en) Remedy for cardiac infraction
JPS5782314A (en) Carcinostatic agent
JPS5634625A (en) Antitumorigenic agent
JPS54125663A (en) Carcinostatic agent and novel compound having carcinostatic activity
JPS5742620A (en) Novel antiulcer agent
JPS5692260A (en) Cyclohexanecarboxylic ester and its preparation
JPS542322A (en) Alkyl n-acylanthranylate derivatives, their preparation, and agricultural and horticultural fungicide containing the same
EP0041298A3 (en) Composition for inhibiting or preventing the development of suckers in tobacco plants
JPS579767A (en) Novel imidazole derivative
JPS57136523A (en) Antipyretic analgesic containing aminobenzoic acid derivative
JPS57136520A (en) Antiarteriosclerotic containing aminobenzoic acid derivative