JPS5782314A - Carcinostatic agent - Google Patents

Carcinostatic agent

Info

Publication number
JPS5782314A
JPS5782314A JP55159851A JP15985180A JPS5782314A JP S5782314 A JPS5782314 A JP S5782314A JP 55159851 A JP55159851 A JP 55159851A JP 15985180 A JP15985180 A JP 15985180A JP S5782314 A JPS5782314 A JP S5782314A
Authority
JP
Japan
Prior art keywords
formula
alkyl
methyl
carcinostatic agent
day
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP55159851A
Other languages
Japanese (ja)
Other versions
JPH0153256B2 (en
Inventor
Akiyoshi Okamoto
Yoshikuni Tamao
Junichi Ooya
Ryoji Kikumoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Kasei Corp
Original Assignee
Mitsubishi Kasei Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Kasei Corp filed Critical Mitsubishi Kasei Corp
Priority to JP55159851A priority Critical patent/JPS5782314A/en
Publication of JPS5782314A publication Critical patent/JPS5782314A/en
Publication of JPH0153256B2 publication Critical patent/JPH0153256B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PURPOSE: A carcinostatic agent that contains N2-arylsulfonyl-L-alginine amide or its salt having activity of inhibiting fibrin caused by antithrombin activity, as an active ingredient.
CONSTITUTION: A compound of formulaI[R1 is formula II (R3 is 3W5C alkyl, 2W4C alkoxyalkyl), formula III (R4 is 1W3C alkyl); R2 is formula IV (R5 and R6 are H, methyl, methoxy, where they are not H, when R5 and R6 are equal) or formula V (R7 is 1W3C alkyl)], or its salt such as 1-[N2-(3-methyl-1,2,3,4-tetrahydro-8-quinolinesulfonyl)-L-alginyl]-4-methyl-2-piperidinecarboxylic acid is contained by 5W100wt% to prepare a carcinostatic agent for oral purpose and by 0.5W20wt% to give for parenteral purposes such as an injection solution. It is given parenterally by 50W1,000mg/kg/day and orally by 100W2,000mg/kg/day.
COPYRIGHT: (C)1982,JPO&Japio
JP55159851A 1980-11-13 1980-11-13 Carcinostatic agent Granted JPS5782314A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP55159851A JPS5782314A (en) 1980-11-13 1980-11-13 Carcinostatic agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55159851A JPS5782314A (en) 1980-11-13 1980-11-13 Carcinostatic agent

Publications (2)

Publication Number Publication Date
JPS5782314A true JPS5782314A (en) 1982-05-22
JPH0153256B2 JPH0153256B2 (en) 1989-11-13

Family

ID=15702613

Family Applications (1)

Application Number Title Priority Date Filing Date
JP55159851A Granted JPS5782314A (en) 1980-11-13 1980-11-13 Carcinostatic agent

Country Status (1)

Country Link
JP (1) JPS5782314A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6431727A (en) * 1987-07-28 1989-02-02 Mitsubishi Chem Ind Dissolution of argininamide and drug composition containing argininamides
US9684135B2 (en) 2013-09-09 2017-06-20 Japan Aviation Electronics Industry, Limited Optoelectrical connector and portable electronic device

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5297934A (en) * 1975-12-09 1977-08-17 Mitsubishi Chem Ind Ltd N#-arylsulfonyl-l-argininamides and their salts acceptable as medicine s
JPS5533499A (en) * 1978-08-31 1980-03-08 Mitsubishi Chem Ind Ltd N2-arylsulfonyl-l-arginineamide and its pharmaceutically acceptable salt

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5297934A (en) * 1975-12-09 1977-08-17 Mitsubishi Chem Ind Ltd N#-arylsulfonyl-l-argininamides and their salts acceptable as medicine s
JPS5533499A (en) * 1978-08-31 1980-03-08 Mitsubishi Chem Ind Ltd N2-arylsulfonyl-l-arginineamide and its pharmaceutically acceptable salt

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6431727A (en) * 1987-07-28 1989-02-02 Mitsubishi Chem Ind Dissolution of argininamide and drug composition containing argininamides
JPH0576929B2 (en) * 1987-07-28 1993-10-25 Mitsubishi Chem Ind
US9684135B2 (en) 2013-09-09 2017-06-20 Japan Aviation Electronics Industry, Limited Optoelectrical connector and portable electronic device

Also Published As

Publication number Publication date
JPH0153256B2 (en) 1989-11-13

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