JPS5782314A - Carcinostatic agent - Google Patents
Carcinostatic agentInfo
- Publication number
- JPS5782314A JPS5782314A JP55159851A JP15985180A JPS5782314A JP S5782314 A JPS5782314 A JP S5782314A JP 55159851 A JP55159851 A JP 55159851A JP 15985180 A JP15985180 A JP 15985180A JP S5782314 A JPS5782314 A JP S5782314A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- alkyl
- methyl
- carcinostatic agent
- day
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PURPOSE: A carcinostatic agent that contains N2-arylsulfonyl-L-alginine amide or its salt having activity of inhibiting fibrin caused by antithrombin activity, as an active ingredient.
CONSTITUTION: A compound of formulaI[R1 is formula II (R3 is 3W5C alkyl, 2W4C alkoxyalkyl), formula III (R4 is 1W3C alkyl); R2 is formula IV (R5 and R6 are H, methyl, methoxy, where they are not H, when R5 and R6 are equal) or formula V (R7 is 1W3C alkyl)], or its salt such as 1-[N2-(3-methyl-1,2,3,4-tetrahydro-8-quinolinesulfonyl)-L-alginyl]-4-methyl-2-piperidinecarboxylic acid is contained by 5W100wt% to prepare a carcinostatic agent for oral purpose and by 0.5W20wt% to give for parenteral purposes such as an injection solution. It is given parenterally by 50W1,000mg/kg/day and orally by 100W2,000mg/kg/day.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55159851A JPS5782314A (en) | 1980-11-13 | 1980-11-13 | Carcinostatic agent |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55159851A JPS5782314A (en) | 1980-11-13 | 1980-11-13 | Carcinostatic agent |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5782314A true JPS5782314A (en) | 1982-05-22 |
JPH0153256B2 JPH0153256B2 (en) | 1989-11-13 |
Family
ID=15702613
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP55159851A Granted JPS5782314A (en) | 1980-11-13 | 1980-11-13 | Carcinostatic agent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5782314A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6431727A (en) * | 1987-07-28 | 1989-02-02 | Mitsubishi Chem Ind | Dissolution of argininamide and drug composition containing argininamides |
US9684135B2 (en) | 2013-09-09 | 2017-06-20 | Japan Aviation Electronics Industry, Limited | Optoelectrical connector and portable electronic device |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5297934A (en) * | 1975-12-09 | 1977-08-17 | Mitsubishi Chem Ind Ltd | N#-arylsulfonyl-l-argininamides and their salts acceptable as medicine s |
JPS5533499A (en) * | 1978-08-31 | 1980-03-08 | Mitsubishi Chem Ind Ltd | N2-arylsulfonyl-l-arginineamide and its pharmaceutically acceptable salt |
-
1980
- 1980-11-13 JP JP55159851A patent/JPS5782314A/en active Granted
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5297934A (en) * | 1975-12-09 | 1977-08-17 | Mitsubishi Chem Ind Ltd | N#-arylsulfonyl-l-argininamides and their salts acceptable as medicine s |
JPS5533499A (en) * | 1978-08-31 | 1980-03-08 | Mitsubishi Chem Ind Ltd | N2-arylsulfonyl-l-arginineamide and its pharmaceutically acceptable salt |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6431727A (en) * | 1987-07-28 | 1989-02-02 | Mitsubishi Chem Ind | Dissolution of argininamide and drug composition containing argininamides |
JPH0576929B2 (en) * | 1987-07-28 | 1993-10-25 | Mitsubishi Chem Ind | |
US9684135B2 (en) | 2013-09-09 | 2017-06-20 | Japan Aviation Electronics Industry, Limited | Optoelectrical connector and portable electronic device |
Also Published As
Publication number | Publication date |
---|---|
JPH0153256B2 (en) | 1989-11-13 |
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