GB2090529A - Thrombosis-prophylactic and curing agent - Google Patents

Thrombosis-prophylactic and curing agent

Info

Publication number
GB2090529A
GB2090529A GB8204905A GB8204905A GB2090529A GB 2090529 A GB2090529 A GB 2090529A GB 8204905 A GB8204905 A GB 8204905A GB 8204905 A GB8204905 A GB 8204905A GB 2090529 A GB2090529 A GB 2090529A
Authority
GB
United Kingdom
Prior art keywords
thrombosis
curing agent
prophylactic
preventing
blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB8204905A
Other versions
GB2090529B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NOF Corp
Original Assignee
Nippon Oil and Fats Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Oil and Fats Co Ltd filed Critical Nippon Oil and Fats Co Ltd
Publication of GB2090529A publication Critical patent/GB2090529A/en
Application granted granted Critical
Publication of GB2090529B publication Critical patent/GB2090529B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A thrombosis-preventing and curing agent containing at least one member selected from among (all-Z)-4, 7, 10, 13, 16, 19-docosahexanoic acid, pharmaceutically acceptable salt, ester and amide thereof as effective ingredient. This agent is absorbed through the intestine so well that it can be used internally, is stable in blood and shows excellent effect of preventing blood platelets from agglutinizing.
GB8204905A 1980-06-27 1981-06-27 Thrombosis-prophylactic and curing agent Expired GB2090529B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8807280A JPS5735512A (en) 1980-06-27 1980-06-27 Preventive and remedy for thrombosis

Publications (2)

Publication Number Publication Date
GB2090529A true GB2090529A (en) 1982-07-14
GB2090529B GB2090529B (en) 1985-04-24

Family

ID=13932644

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8204905A Expired GB2090529B (en) 1980-06-27 1981-06-27 Thrombosis-prophylactic and curing agent

Country Status (3)

Country Link
JP (1) JPS5735512A (en)
GB (1) GB2090529B (en)
WO (1) WO1982000095A1 (en)

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4607052A (en) * 1983-04-15 1986-08-19 Roussel-Uclaf Triglycerides, dietetic and therapeutical applications and compositions containing them
US4701469A (en) * 1983-04-15 1987-10-20 Roussel Uclaf Triglycerides, process for therapeutical applications and compositions containing them
GB2218904A (en) * 1988-05-27 1989-11-29 Renafield Limited Pharmaceutical composition based on high-concentration esters of docosahexaenoic acid
WO1989011521A1 (en) * 1988-05-27 1989-11-30 Staroil Limited Process for preparing polyunsaturated fatty acids
US4910224A (en) * 1986-02-14 1990-03-20 Habib Nagy A Method of modifying the lipid structure and function of cell membranes and pharmaceutical compositions for use therein
WO1990004391A1 (en) * 1988-10-21 1990-05-03 J.B. Tillott Limited Oral dosage forms of omega-3 polyunsaturated acids
FR2643637A1 (en) * 1989-02-27 1990-08-31 Natura Medica Laboratoires CALCIUM ION COMPLEX WITH AT LEAST ONE UNSATURATED FATTY ACID, BIOMEDIATING AGENT COMPRISING SUCH A COMPLEX, PHARMACEUTICAL COMPOSITION INCORPORATING SAME AND PLANT OR ORGAN EXTRACTS CONTAINING THE SAME
US4960795A (en) * 1987-12-21 1990-10-02 Norsk Hydro A.S. Feed additive and feed containing such additive
US5502077A (en) * 1988-08-11 1996-03-26 Norsk Hydro A.S. Fatty acid composition
US7439267B2 (en) 2001-01-25 2008-10-21 Pfizer Italia S.R.L. Essential n-3 fatty acids in cardiac insufficiency and heart failure therapy
US8383678B2 (en) 2004-02-13 2013-02-26 Chrysalis Pharma Ag Type a gelatin capsule containing PUFA in free acid form
US9050309B2 (en) 2012-01-06 2015-06-09 Omthera Pharmaceuticals, Inc. DPA-enriched compositions of omega-3 polyunsaturated fatty acids in free acid form
CN104958725A (en) * 2015-07-05 2015-10-07 四川金堂海纳生物医药技术研究所 Oral administration medicament for treating venous thrombosis and preparation method thereof
US9492545B2 (en) 2012-05-07 2016-11-15 Omthera Pharmaceuticals Inc. Compositions of statins and omega-3 fatty acids

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3307244A1 (en) * 1982-08-06 1984-02-16 Theodor 6450 Hanau Splithoff Carrier preferably for holding a sign
JPH0615469B2 (en) * 1984-05-09 1994-03-02 テルモ株式会社 Fat infusion
JPS60248610A (en) * 1984-05-23 1985-12-09 Nitsusui Seiyaku Kk Preventive and remedy for complicated diabetes
DE3615710A1 (en) * 1986-05-09 1987-11-26 Hoechst Ag PREPARATIONS FOR THE SYNTHESIS OF PROSTAGLANDINES AND HYDROXY FATTY ACIDS IN BIOLOGICAL SYSTEMS
JP2524217B2 (en) * 1988-04-18 1996-08-14 マルハ株式会社 Brain function improving composition, learning ability enhancing agent, memory enhancing agent, dementia preventive agent or dementia therapeutic agent

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU527784B2 (en) * 1978-05-26 1983-03-24 Bang, Hans Olaf Dr. Treatment of thromboembolic conditions withall-z)-5, 8, 11, 14, 17-eicosapentaenoic acid
ZA784083B (en) * 1978-05-26 1980-02-27 Wellcome Found Fatty acid and derivatives thereof,and formulations containing them for use in treatment or prophyllaxis of thrombo-embolic conditions

Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4701469A (en) * 1983-04-15 1987-10-20 Roussel Uclaf Triglycerides, process for therapeutical applications and compositions containing them
US4607052A (en) * 1983-04-15 1986-08-19 Roussel-Uclaf Triglycerides, dietetic and therapeutical applications and compositions containing them
US4910224A (en) * 1986-02-14 1990-03-20 Habib Nagy A Method of modifying the lipid structure and function of cell membranes and pharmaceutical compositions for use therein
US4960795A (en) * 1987-12-21 1990-10-02 Norsk Hydro A.S. Feed additive and feed containing such additive
GB2218904A (en) * 1988-05-27 1989-11-29 Renafield Limited Pharmaceutical composition based on high-concentration esters of docosahexaenoic acid
WO1989011521A1 (en) * 1988-05-27 1989-11-30 Staroil Limited Process for preparing polyunsaturated fatty acids
GR890100345A (en) * 1988-05-27 1991-10-10 Staroil Ltd Process for preparing high concentration mixtures of polysaturated fatty acids and their esters from oils of animal and or vegetable origin
US5502077A (en) * 1988-08-11 1996-03-26 Norsk Hydro A.S. Fatty acid composition
US5698594A (en) * 1988-08-11 1997-12-16 Norsk Hydro A.S Treatment and prevention of risk factors for cardiovascular diseases
US5656667A (en) * 1988-08-11 1997-08-12 Norsk Hydro As Fatty acid composition
WO1990004391A1 (en) * 1988-10-21 1990-05-03 J.B. Tillott Limited Oral dosage forms of omega-3 polyunsaturated acids
WO1990009977A1 (en) * 1989-02-27 1990-09-07 Laboratoires Natura Medica Calcium ion complex with at least one unsaturated acid and pharmaceutical composition incorporating it
FR2643637A1 (en) * 1989-02-27 1990-08-31 Natura Medica Laboratoires CALCIUM ION COMPLEX WITH AT LEAST ONE UNSATURATED FATTY ACID, BIOMEDIATING AGENT COMPRISING SUCH A COMPLEX, PHARMACEUTICAL COMPOSITION INCORPORATING SAME AND PLANT OR ORGAN EXTRACTS CONTAINING THE SAME
US7439267B2 (en) 2001-01-25 2008-10-21 Pfizer Italia S.R.L. Essential n-3 fatty acids in cardiac insufficiency and heart failure therapy
US8383678B2 (en) 2004-02-13 2013-02-26 Chrysalis Pharma Ag Type a gelatin capsule containing PUFA in free acid form
US9012501B2 (en) 2004-02-13 2015-04-21 Chrysalis Pharma Ag Type A gelatin capsule containing PUFA in free acid form
US9132112B2 (en) 2004-02-13 2015-09-15 Chysalis Pharma Ag Type A gelatin capsule containing PUFA in free acid form
US9050309B2 (en) 2012-01-06 2015-06-09 Omthera Pharmaceuticals, Inc. DPA-enriched compositions of omega-3 polyunsaturated fatty acids in free acid form
US9050308B2 (en) 2012-01-06 2015-06-09 Omthera Pharmaceuticals, Inc. DPA-enriched compositions of omega-3 polyunsaturated fatty acids in free acid form
US10117844B2 (en) 2012-01-06 2018-11-06 Omthera Pharmaceuticals, Inc. DPA-enriched compositions of omega-3 polyunsaturated fatty acids in free acid form
US9492545B2 (en) 2012-05-07 2016-11-15 Omthera Pharmaceuticals Inc. Compositions of statins and omega-3 fatty acids
CN104958725A (en) * 2015-07-05 2015-10-07 四川金堂海纳生物医药技术研究所 Oral administration medicament for treating venous thrombosis and preparation method thereof

Also Published As

Publication number Publication date
JPS5735512A (en) 1982-02-26
GB2090529B (en) 1985-04-24
JPH0141604B2 (en) 1989-09-06
WO1982000095A1 (en) 1982-01-21

Similar Documents

Publication Publication Date Title
GB2090529A (en) Thrombosis-prophylactic and curing agent
FR2531857B1 (en) INJECTABLE COMPOSITION FOR PROLONGING THE STABILITY AND RETENTION OF COATED PARTICLES INJECTED INTO THE BLOOD FLOW OF ANIMALS AND HUMAN BEINGS
IL80149A (en) Pharmaceutical compositions containing toluidide derivatives against graft-versus-host diseases and autoimmune diseases
ES525743A0 (en) PROCEDURE FOR THE MANUFACTURE OF 4'-DEMETIL-EPIPODOFILOTOXIN-B-D-ETILIDEN-GLUCOSIDO AND ACYLIC DERIVATIVE OF THE SAME
ZA812088B (en) Derivative of saccharide and physiologically active agent containing the same
TR22285A (en) BIOLOGICAL STRUGGLE PROCEDURES AND INSECTICIDE COMPOSITIONS TO THE VICINES THAT DESTROY THE KUELTUERS
JPS56154417A (en) Use of 3,3'-azobis -(6-hydroxybenzoic acid) as drug and pharmaceutical composition containing it
JPS6434909A (en) Cosmetic
IL67940A0 (en) 2,3-diaryl-5-halo-thiophenes,their preparation and pharmaceutical compositions containing them
GB2071091B (en) Acyl-derivatives of carnitine and the therapeutic use thereof
DE3162659D1 (en) 9,11-methano-13-aza-11a-carbathrombanoic acid analogues and pharmaceutical use thereof
JPS57175101A (en) Killing agent composition for furniture treatment
GB2106392B (en) Bactericidal and fungicidal agent and aqueous formulations containing same
JPS5795970A (en) 5-chloro-benzoxazole-2-yl-oxyacetic acid amide and use as herbicide
JPS57142905A (en) Liquid creature killing drug, manufacture and use
EP0147707A3 (en) 1,7-diphenyl-3-methylaza-7-cyano-8-methylnonane useful in combating diseases
IL65443A (en) Calcium salts of beta-(4,5-diphenyl-oxazol-2-yl)-propionic acid and pharmaceutical compositions containing them
IT1214843B (en) SYNERGISTIC PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF HEPATIC DISORDERS CONTAINING 4 (5) -AMINOIMIDAZOLE-5 (4) CARBOXAMIDE ORTHOPHOSPHATE AND VITAMINS
IT8323601A0 (en) USE OF IBUPROFEN AND FLURBIPROFEN IN THE TREATMENT OF HERPESES.
DE3272384D1 (en) Medicinal composition for the treatment of certain neuroviroses
FR2336945A1 (en) COMPOSITION FOR THE STERILIZATION OF FEMALE AND FEMALE ANIMALS
EP0059346A3 (en) Therapeutic agent and the use thereof
IT7824578A0 (en) PHARMACEUTICAL COMPOSITION FOR THE THERAPY OF STATES OF FRIGIDITY AND IMPOTENCE.
DK602284D0 (en) PROCEDURE FOR THE PREPARATION OF 2,4,6-TRIIODOPHENOL AND ITS APPLICATION FOR THERAPEUTIC PURPOSES
IL64827A0 (en) Fungicidal compositions containing certain amino acid derivatives and the preparation of these derivatives

Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Effective date: 20010626