ES2136189T3 - Lipidos estructurados. - Google Patents

Lipidos estructurados.

Info

Publication number
ES2136189T3
ES2136189T3 ES94906082T ES94906082T ES2136189T3 ES 2136189 T3 ES2136189 T3 ES 2136189T3 ES 94906082 T ES94906082 T ES 94906082T ES 94906082 T ES94906082 T ES 94906082T ES 2136189 T3 ES2136189 T3 ES 2136189T3
Authority
ES
Spain
Prior art keywords
residue
series
linolenic acid
acid
prostanoid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94906082T
Other languages
English (en)
Inventor
Stephen Joseph Demichele
Michael Donald Karlstad
Bruce Ryan Bistrian
Edward Anthony Mascioli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of ES2136189T3 publication Critical patent/ES2136189T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/52Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
    • C07C69/587Monocarboxylic acid esters having at least two carbon-to-carbon double bonds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115Fatty acids or derivatives thereof; Fats or oils
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12Fatty acids or derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SE DESCRIBE UN LIPIDO ESTRUCTURADO QUE CONTIENE O UN ACIDO GAMMA-LINOLENICO O UN RESIDUO DE ACIDO DIHOMOGAMMA-LINOLENICO, JUNTO CON UN RESIDUO DE ACIDO N-3 GRASO Y UN RESIDUO DE ACIDO GRASO DE CADENA MEDIA EN LA MISMA ESTRUCTURA DE GLICEROL. ESTE LIPIDO ESTRUCTURADO ESTA PARTICULARMENTE BIEN ADAPTADO PARA EL TRATAMIENTO DE ESTADOS DE ENFERMEDAD O ESTRES. LOS RESIDUOS DE ACIDO GAMMA-LINOLENICO O DIHOMOGAMMA-LINOLENICO MODIFICAN LA RUTA DE SINTESIS PROSTANOIDE, REDUCIENDO EL NIVEL DE PROSTANOIDES DE SERIE "2" Y ELEVANDO LOS NIVELES DE PROSTANOIDES DE SERIE "1" Y "3". EL RESIDUO DE ACIDO N-3 GRASO MEJORA EL NIVEL DE PROSTANOIDES DE SERIE "1" ASI COMO AUMENTA LA PRODUCCION DE PROSTANOIDES DE SERIE "3". LOS RESIDUOS DE ACIDO GRASO DE CADENA MEDIA MEJORAN LA ABSORCION DEL LIPIDO ESTRUCTURADO. TAMBIEN SE DESCRIBE DIETAS ENTERALES Y PARENTERALES ASI COMO SUPLEMENTOS NUTRICIONALES QUE CONTIENEN LOS LIPIDOS ESTRUCTURADOS DE LA INVENCION.
ES94906082T 1993-01-15 1994-01-13 Lipidos estructurados. Expired - Lifetime ES2136189T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US482893A 1993-01-15 1993-01-15

Publications (1)

Publication Number Publication Date
ES2136189T3 true ES2136189T3 (es) 1999-11-16

Family

ID=21712725

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94906082T Expired - Lifetime ES2136189T3 (es) 1993-01-15 1994-01-13 Lipidos estructurados.

Country Status (7)

Country Link
US (2) US5661180A (es)
EP (1) EP0679057B1 (es)
AU (1) AU5995294A (es)
CA (1) CA2151820C (es)
DE (1) DE69420124T2 (es)
ES (1) ES2136189T3 (es)
WO (1) WO1994015464A1 (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4417851C1 (de) * 1994-05-20 1995-10-05 Horst Heirler Diätetisches Lebensmittel mit mittelkettigen Fettsäuren und dessen Verwendung
GB9506837D0 (en) * 1995-04-03 1995-05-24 Scotia Holdings Plc Triglycerides
US6200624B1 (en) * 1996-01-26 2001-03-13 Abbott Laboratories Enteral formula or nutritional supplement containing arachidonic and docosahexaenoic acids
WO1997046220A1 (en) * 1996-06-03 1997-12-11 Croda International Plc Vegetable oil compositions
US6340485B1 (en) 1996-06-03 2002-01-22 Croda International Plc Compositions and uses thereof
US6013665A (en) * 1997-12-16 2000-01-11 Abbott Laboratories Method for enhancing the absorption and transport of lipid soluble compounds using structured glycerides
US6054481A (en) 1998-01-21 2000-04-25 Fideline Pig appeasing pheromones for enhancing weight gain in a mammal
EP0948963B1 (en) * 1998-01-21 2003-05-07 Fideline Pig appeasing pheromones to decrease stress, anxiety and aggressiveness
US6369252B1 (en) 1998-02-26 2002-04-09 The University Of Georgia Research Foundation, Inc. Structured lipids
US6194379B1 (en) 1998-05-01 2001-02-27 Abbott Laboratories Elemental enteral formula
EP1090636A1 (en) * 1999-09-13 2001-04-11 Société des Produits Nestlé S.A. High lipid diet
US6720001B2 (en) * 1999-10-18 2004-04-13 Lipocine, Inc. Emulsion compositions for polyfunctional active ingredients
US6228367B1 (en) * 1999-12-22 2001-05-08 Renew Life, Inc. Food supplement formulation
US6864242B2 (en) * 2001-03-05 2005-03-08 Stephen P. Ernest Enteral formulation
WO2003033632A1 (en) 2001-10-18 2003-04-24 Council Of Scientific And Industrial Research Cholesterol lowering structured lipids with omega 6 pufa
US6793959B2 (en) * 2002-03-18 2004-09-21 Bunge Foods Corporation Low viscosity structured lipid pan release compositions and methods
US7041840B2 (en) 2002-12-18 2006-05-09 Alberta Research Council Inc. Antioxidant triacylglycerols and lipid compositions
GB0311081D0 (en) * 2003-05-14 2003-06-18 Btg Internat Limted Treatment of neurodegenerative conditions
CA2436650A1 (en) * 2003-08-06 2005-02-06 Naturia Inc. Conjugated linolenic acid (clnatm) compositions: synthesis, purification and uses
GB2422373B (en) 2003-08-18 2008-05-21 Btg Int Ltd Treatment of neurodegenerative conditions
EP1704266A2 (en) * 2003-12-22 2006-09-27 Cabot Corporation High integrity sputtering target material and method for producing bulk quantities of same
US7919526B2 (en) * 2004-03-04 2011-04-05 Htl High-Tech Lipids Ltd. Structured triglycerides and emulsions comprising same
GB0425932D0 (en) * 2004-11-25 2004-12-29 Btg Int Ltd Structured phospholipids
GB0504362D0 (en) 2005-03-02 2005-04-06 Btg Int Ltd Cytokine modulators
GB0504333D0 (en) * 2005-03-02 2005-04-06 Btg Int Ltd Treatment of cytokine dysregulation
US20070218183A1 (en) * 2006-03-14 2007-09-20 Bunge Oils, Inc. Oil composition of conjugated linoleic acid
US20100130442A1 (en) * 2007-05-07 2010-05-27 Raj Wadgaonkar Lung Injury Treatment
US8652508B2 (en) 2007-05-25 2014-02-18 Children's Medical Center Corporation Dietary formulations and methods for treatment of inflammation and other disorders
CN107050457A (zh) 2012-01-06 2017-08-18 翁特拉制药公司 游离酸形式的ω‑3多不饱和脂肪酸的富含dpa组合物
EP2846779A4 (en) 2012-05-07 2015-12-16 Omthera Pharmaceuticals Inc STATIN AND OMEGA-3 FATTY ACID COMPOSITIONS
CA3036516A1 (en) 2016-09-13 2018-03-22 Abbott Laboratories Ketogenic nutritional compositions

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US4273763A (en) * 1978-01-23 1981-06-16 Efamol Limited Pharmaceutical and dietary compositions
EP0004770B1 (en) * 1978-04-11 1984-06-13 Efamol Limited Pharmaceutical and dietary composition comprising gamma-linolenic acids
ATE24266T1 (de) * 1982-04-16 1987-01-15 Nestle Sa Lipidhaltige zusammensetzung fuer die orale, enterale oder parenterale ernaehrung.
EP0093516B1 (en) * 1982-04-29 1986-10-01 Efamol Limited Pharmaceutical composition
US4528197A (en) * 1983-01-26 1985-07-09 Kabivitrum Ab Controlled triglyceride nutrition for hypercatabolic mammals
US4607052A (en) * 1983-04-15 1986-08-19 Roussel-Uclaf Triglycerides, dietetic and therapeutical applications and compositions containing them
US4701469A (en) * 1983-04-15 1987-10-20 Roussel Uclaf Triglycerides, process for therapeutical applications and compositions containing them
US4685534A (en) * 1983-08-16 1987-08-11 Burstein A Lincoln Method and apparatus for control of fluids
US4526902A (en) * 1983-10-24 1985-07-02 Century Laboratories, Inc. Combined fatty acid composition for treatment or prophylaxis of thrombo-embolic conditions
US4871768A (en) * 1984-07-12 1989-10-03 New England Deaconess Hospital Corporation Dietary supplement utilizing ω-3/medium chain trigylceride mixtures
US4752618A (en) * 1984-07-12 1988-06-21 New England Deaconess Hospital Method of minimizing efects of infection through diet
GB8425006D0 (en) * 1984-10-03 1984-11-07 Efamol Ltd Composition of copper/fatty acids
GB8506027D0 (en) * 1985-03-08 1985-04-11 Efamol Ltd Pharmaceutical & dietary compositions
US4753963A (en) * 1985-09-26 1988-06-28 The Procter & Gamble Company Nutritional fat suitable for enteral and parenteral products
GB8524276D0 (en) * 1985-10-02 1985-11-06 Efamol Ltd Pharmaceutical & dietary compositions
DE3615710A1 (de) * 1986-05-09 1987-11-26 Hoechst Ag Zubereitungen fuer die synthese von prostaglandinen und hydroxyfettsaeuren in biologischen systemen
US5227403A (en) * 1986-10-01 1993-07-13 The Nisshin Oil Mills, Ltd. Fats and oils having superior digestibility and absorptivity
JPS6387988A (ja) * 1986-10-01 1988-04-19 Nisshin Oil Mills Ltd:The 消化吸収性の良い油脂
FR2617161B1 (fr) * 1987-06-29 1989-10-27 Azar Robert Nouveaux glycerides d'acide gras insature et leur procede d'obtention
WO1989000239A1 (fr) * 1987-07-06 1989-01-12 Komatsu Zenoah Kabushiki Kaisha Starter pour moteurs
US4843095A (en) * 1987-08-07 1989-06-27 Century Laboratories, Inc. Free fatty acids for treatment or propyhlaxis of rheumatoid arthritis arthritis
GB8718952D0 (en) * 1987-08-11 1987-09-16 Sowden G G Shredder unit
US4906664A (en) * 1988-01-15 1990-03-06 New England Deaconess Hospital Corporation Nutritional supplement for treatment of cancer cachexia
US5081105A (en) * 1988-01-15 1992-01-14 New England Deaconess Hospital Corporation Method of treating cancer using structured lipids
DK565288D0 (da) * 1988-10-11 1988-10-11 Novo Industri As Fremgangsmaade til fremstilling af triglycerider, anvendelse af saadanne triglycerider og en emulsion, der indeholder saadanne triglycerider
US5196198A (en) * 1989-06-02 1993-03-23 Abbott Laboratories Parenteral nutrition product
FR2652588A1 (fr) * 1989-10-04 1991-04-05 Medgenix Group Sa Procede de production d'un melange de glycerides enrichis en acides gras.

Also Published As

Publication number Publication date
US5661180A (en) 1997-08-26
DE69420124T2 (de) 2000-03-02
CA2151820A1 (en) 1994-07-21
US5962712A (en) 1999-10-05
CA2151820C (en) 2000-11-28
EP0679057B1 (en) 1999-08-18
EP0679057A1 (en) 1995-11-02
WO1994015464A1 (en) 1994-07-21
EP0679057A4 (en) 1996-01-17
DE69420124D1 (de) 1999-09-23
AU5995294A (en) 1994-08-15

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