PE20142459A1 - Composiciones enriquecidas con dpa de acidos grasos omega 3 poliinsaturados en forma de acido libre - Google Patents

Composiciones enriquecidas con dpa de acidos grasos omega 3 poliinsaturados en forma de acido libre

Info

Publication number
PE20142459A1
PE20142459A1 PE2014001081A PE2014001081A PE20142459A1 PE 20142459 A1 PE20142459 A1 PE 20142459A1 PE 2014001081 A PE2014001081 A PE 2014001081A PE 2014001081 A PE2014001081 A PE 2014001081A PE 20142459 A1 PE20142459 A1 PE 20142459A1
Authority
PE
Peru
Prior art keywords
dpa
free acid
polyinsaturated
omega
fatty acids
Prior art date
Application number
PE2014001081A
Other languages
English (en)
Inventor
Timothy J Maines
Bernardus Nicolass Machielse
Bharat M Mehta
Gerald Wisler
Michael H Davidson
Peter Ralph Wood
Original Assignee
Omthera Pharmaceuticals Inc
Chrysalis Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48744082&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20142459(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Omthera Pharmaceuticals Inc, Chrysalis Pharma Ag filed Critical Omthera Pharmaceuticals Inc
Publication of PE20142459A1 publication Critical patent/PE20142459A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Materials For Photolithography (AREA)

Abstract

REFERIDA A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE EN FORMA DE ACIDO LIBRE: EPA (ACIDO EICOSAPENTANOICO) EN UNA CANTIDAD DE ENTRE 50% (m/m) A 60% (m/m), DHA (ACIDO DOCOSAHEXANOICO) EN UNA CANTIDAD DE ENTRE 15% (m/m) A 25% (m/m) Y DPA EN UNA CANTIDAD DE NO MENOS DEL 1% (m/m). DICHA COMPOSICION ES UTIL EN EL TRATAMIENTO DE LA HIPERTRIGLICERIDEMIA, PARA REDUCIR O PREVENIR LA RESISTENCIA A LOS INHIBIDORES DE LA AGREGACION PLAQUETARIA, ENTRE OTROS
PE2014001081A 2012-01-06 2013-01-04 Composiciones enriquecidas con dpa de acidos grasos omega 3 poliinsaturados en forma de acido libre PE20142459A1 (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201261583796P 2012-01-06 2012-01-06
US201261664047P 2012-06-25 2012-06-25
US201261669940P 2012-07-10 2012-07-10
US201261680622P 2012-08-07 2012-08-07
US201261710517P 2012-10-05 2012-10-05
US201261713388P 2012-10-12 2012-10-12

Publications (1)

Publication Number Publication Date
PE20142459A1 true PE20142459A1 (es) 2015-01-23

Family

ID=48744082

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2014001081A PE20142459A1 (es) 2012-01-06 2013-01-04 Composiciones enriquecidas con dpa de acidos grasos omega 3 poliinsaturados en forma de acido libre

Country Status (34)

Country Link
US (5) US20150004224A1 (es)
EP (2) EP2800563B1 (es)
JP (3) JP6399655B2 (es)
KR (2) KR102153143B1 (es)
CN (3) CN108524483A (es)
BR (1) BR112014016788A8 (es)
CA (1) CA2860512C (es)
CL (1) CL2014001803A1 (es)
CO (1) CO7061070A2 (es)
CY (1) CY1120663T1 (es)
DK (1) DK2800563T3 (es)
DO (1) DOP2014000159A (es)
EC (1) ECSP14012527A (es)
ES (1) ES2685703T3 (es)
HK (2) HK1251457A1 (es)
HR (1) HRP20181418T1 (es)
HU (1) HUE039659T2 (es)
IL (3) IL233517A (es)
IN (1) IN2014DN06125A (es)
LT (1) LT2800563T (es)
MX (1) MX358319B (es)
MY (1) MY165048A (es)
NZ (1) NZ626699A (es)
PE (1) PE20142459A1 (es)
PH (2) PH12014501553A1 (es)
PL (1) PL2800563T3 (es)
PT (1) PT2800563T (es)
RS (1) RS57777B1 (es)
RU (2) RU2018116572A (es)
SG (2) SG10201701004RA (es)
SI (1) SI2800563T1 (es)
UA (1) UA114615C2 (es)
WO (1) WO2013103902A1 (es)
ZA (1) ZA201405765B (es)

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