HK1064301A1 - Preparation of a lipid blend and a phospholipid suspension containing the lipid blend, and contrast agents based on these - Google Patents

Preparation of a lipid blend and a phospholipid suspension containing the lipid blend, and contrast agents based on these

Info

Publication number
HK1064301A1
HK1064301A1 HK04107194.5A HK04107194A HK1064301A1 HK 1064301 A1 HK1064301 A1 HK 1064301A1 HK 04107194 A HK04107194 A HK 04107194A HK 1064301 A1 HK1064301 A1 HK 1064301A1
Authority
HK
Hong Kong
Prior art keywords
lipid blend
preparation
suspension containing
contrast agents
agents based
Prior art date
Application number
HK04107194.5A
Other languages
English (en)
Inventor
Poh K Hui
John E Bishop
Eleodoro S Madrigal Jr
Original Assignee
Lantheus Medical Imaging Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lantheus Medical Imaging Inc filed Critical Lantheus Medical Imaging Inc
Publication of HK1064301A1 publication Critical patent/HK1064301A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/226—Solutes, emulsions, suspensions, dispersions, semi-solid forms, e.g. hydrogels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/227—Liposomes, lipoprotein vesicles, e.g. LDL or HDL lipoproteins, micelles, e.g. phospholipidic or polymeric
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Acoustics & Sound (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK04107194.5A 1998-01-14 2004-09-17 Preparation of a lipid blend and a phospholipid suspension containing the lipid blend, and contrast agents based on these HK1064301A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7133298P 1998-01-14 1998-01-14

Publications (1)

Publication Number Publication Date
HK1064301A1 true HK1064301A1 (en) 2005-01-28

Family

ID=22100659

Family Applications (1)

Application Number Title Priority Date Filing Date
HK04107194.5A HK1064301A1 (en) 1998-01-14 2004-09-17 Preparation of a lipid blend and a phospholipid suspension containing the lipid blend, and contrast agents based on these

Country Status (31)

Country Link
US (8) US20010003580A1 (fr)
EP (2) EP1419789B1 (fr)
JP (2) JP5160702B2 (fr)
KR (1) KR100711663B1 (fr)
CN (1) CN1191822C (fr)
AR (1) AR016444A1 (fr)
AT (1) ATE447976T1 (fr)
AU (1) AU746067C (fr)
BR (1) BR9907066A (fr)
CA (1) CA2317921C (fr)
DE (1) DE69941634D1 (fr)
DK (1) DK1419789T3 (fr)
EA (1) EA002978B1 (fr)
EE (1) EE04900B1 (fr)
ES (1) ES2336669T3 (fr)
HK (1) HK1064301A1 (fr)
HR (1) HRP990012A2 (fr)
HU (1) HUP0100206A3 (fr)
IL (2) IL137018A0 (fr)
MY (1) MY137255A (fr)
NO (1) NO321866B1 (fr)
NZ (1) NZ505082A (fr)
PH (1) PH12012000094A1 (fr)
PL (1) PL193672B1 (fr)
PT (1) PT1419789E (fr)
SI (1) SI1419789T1 (fr)
SK (1) SK285333B6 (fr)
TW (1) TWI242448B (fr)
UA (1) UA75023C2 (fr)
WO (1) WO1999036104A2 (fr)
ZA (1) ZA99247B (fr)

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US20010003580A1 (en) 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
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US20030049158A1 (en) * 2001-04-03 2003-03-13 Hui Poh K. Stablization and terminal sterilization of phospholipid formulations
SI1476201T1 (sl) 2002-02-19 2009-06-30 Resolution Chemicals Ltd Sterilizacija steroidov, osnovana na topilu
US9364569B2 (en) * 2003-02-04 2016-06-14 Bracco Suisse S.A. Ultrasound contrast agents and process for the preparation thereof
CA2547024C (fr) 2003-12-22 2013-12-17 Bracco Research Sa Systeme de microvesicule remplie de gaz pour l'imagerie de contraste
CN1321697C (zh) * 2003-12-23 2007-06-20 中国人民解放军军事医学科学院毒物药物研究所 一种以磷脂类成分为成膜材料的超声造影剂组合物及其制备方法
US7854943B2 (en) 2004-06-24 2010-12-21 Idexx Laboratories Phospholipid gel compositions for drug delivery and methods of treating conditions using same
US7858115B2 (en) * 2004-06-24 2010-12-28 Idexx Laboratories Phospholipid gel compositions for drug delivery and methods of treating conditions using same
US7618651B2 (en) 2004-06-24 2009-11-17 Idexx Laboratories Pharmaceutical compositions for drug delivery and methods of treating or preventing conditions using same
WO2006018433A1 (fr) 2004-08-18 2006-02-23 Bracco Research Sa Composition renfermant des microvesicules remplies de gaz, destinee a l'imagerie de contraste
US8017159B2 (en) * 2005-11-16 2011-09-13 Idexx Laboratories, Inc. Phospholipid gel compositions for delivery of aptamers and methods of treating conditions using same
KR20110110086A (ko) * 2008-12-24 2011-10-06 가부시키가이샤 바이오메드코어 리포솜의 제조방법 및 콜레스테롤의 용해방법
JP5771366B2 (ja) * 2009-09-02 2015-08-26 株式会社バイオメッドコア リポソーム製造装置及び方法
JP2012086166A (ja) * 2010-10-20 2012-05-10 Biomedcore Inc リポソーム製造装置
WO2014138035A1 (fr) 2013-03-04 2014-09-12 Echogen Power Systems, L.L.C. Systèmes de moteur thermique possédant des circuits de dioxyde de carbone supercritique à haute énergie nette
TWI552761B (zh) * 2013-05-03 2016-10-11 博信生物科技股份有限公司 一種脂質微／奈米氣泡、及其最佳化之製備方法及製備裝置
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KR20230015509A (ko) * 2014-10-30 2023-01-31 랜티우스 메디컬 이메징, 인크. 지질 캡슐화된 기체 마이크로스피어 조성물 및 관련된 방법
US10570777B2 (en) 2014-11-03 2020-02-25 Echogen Power Systems, Llc Active thrust management of a turbopump within a supercritical working fluid circuit in a heat engine system
CN107206111B (zh) 2014-12-31 2021-04-27 蓝瑟斯医学影像公司 脂质封装的气体微球组合物及相关方法
CN109641068B (zh) * 2016-05-04 2022-09-30 蓝瑟斯医学影像公司 用于制备超声波造影剂的方法及装置
US9789210B1 (en) 2016-07-06 2017-10-17 Lantheus Medical Imaging, Inc. Methods for making ultrasound contrast agents
WO2019036253A1 (fr) * 2017-08-15 2019-02-21 The Board Of Trustees Of The Leland Stanford Junior University Nanoémulsions de perfluorocarbone polymère pour la libération de médicament par ultrasons
EP3905995A4 (fr) 2019-01-04 2022-08-31 California Institute of Technology Procédé d'élimination de lentille oculaire à l'aide de microbulles de cavitation
RU2745290C2 (ru) * 2019-04-12 2021-03-23 Ирина Николаевна Кузнецова Эмульсия перфторуглеродных соединений медико-биологического назначения и способ её получения
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PL342473A1 (en) 2001-06-04
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US20120128595A1 (en) 2012-05-24
CA2317921A1 (fr) 1999-07-22
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JP5160702B2 (ja) 2013-03-13
ATE447976T1 (de) 2009-11-15
NO321866B1 (no) 2006-07-17
ZA99247B (en) 2000-07-14
KR20010034106A (ko) 2001-04-25
US20150023880A1 (en) 2015-01-22
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