ATE88093T1 - Ausscheidung von prozesschemikalien aus biologischen gemischen mit halogenierten kohlenwasserstoffen. - Google Patents

Ausscheidung von prozesschemikalien aus biologischen gemischen mit halogenierten kohlenwasserstoffen.

Info

Publication number
ATE88093T1
ATE88093T1 AT88121582T AT88121582T ATE88093T1 AT E88093 T1 ATE88093 T1 AT E88093T1 AT 88121582 T AT88121582 T AT 88121582T AT 88121582 T AT88121582 T AT 88121582T AT E88093 T1 ATE88093 T1 AT E88093T1
Authority
AT
Austria
Prior art keywords
biological material
halogenated
lipid soluble
hydrocarbs
removal
Prior art date
Application number
AT88121582T
Other languages
English (en)
Inventor
Bernard Horowitz
Richard J Bonomo
Original Assignee
New York Blood Center Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New York Blood Center Inc filed Critical New York Blood Center Inc
Application granted granted Critical
Publication of ATE88093T1 publication Critical patent/ATE88093T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/02—Recovery or purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/647—Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/18—Erythrocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088—Liquid substances
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Extraction Or Liquid Replacement (AREA)
AT88121582T 1987-12-30 1988-12-23 Ausscheidung von prozesschemikalien aus biologischen gemischen mit halogenierten kohlenwasserstoffen. ATE88093T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/139,502 US4909940A (en) 1987-12-30 1987-12-30 Extraction of process chemicals from labile biological mixtures with organic alcohols or with halogenated hydrocarbons
EP88121582A EP0322786B1 (de) 1987-12-30 1988-12-23 Ausscheidung von Prozesschemikalien aus biologischen Gemischen mit halogenierten Kohlenwasserstoffen

Publications (1)

Publication Number Publication Date
ATE88093T1 true ATE88093T1 (de) 1993-04-15

Family

ID=22486977

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88121582T ATE88093T1 (de) 1987-12-30 1988-12-23 Ausscheidung von prozesschemikalien aus biologischen gemischen mit halogenierten kohlenwasserstoffen.

Country Status (6)

Country Link
US (1) US4909940A (de)
EP (1) EP0322786B1 (de)
JP (1) JP2742806B2 (de)
KR (1) KR890010193A (de)
AT (1) ATE88093T1 (de)
DE (1) DE3880292T2 (de)

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US5094960A (en) * 1988-10-07 1992-03-10 New York Blood Center, Inc. Removal of process chemicals from labile biological mixtures by hydrophobic interaction chromatography
US5418130A (en) * 1990-04-16 1995-05-23 Cryopharm Corporation Method of inactivation of viral and bacterial blood contaminants
US6187572B1 (en) 1990-04-16 2001-02-13 Baxter International Inc. Method of inactivation of viral and bacterial blood contaminants
US5071650A (en) * 1990-06-04 1991-12-10 Miles Inc. Use of intermediate length alcohols as virucidal agents in solutions of biologically active proteins
BE1005163A3 (fr) * 1991-08-01 1993-05-11 Solvay Compositions contenant un ether fluore et utilisation de ces compositions.
DE4125625C2 (de) * 1991-08-02 1999-12-02 Octapharma Ag Glarus Verfahren zur Herstellung von virusinaktivierten Immunglobulinlösungen
JPH06511016A (ja) * 1992-05-04 1994-12-08 シャンブロム、エドワード 安全な生物流体
DE4227130A1 (de) * 1992-08-17 1994-02-24 Solvay Fluor & Derivate Zusammensetzungen aus 1-Chlor-2,2,2-trifluorethyldifluormethylether und partiell fluorierten Alkanolen
DK0710126T3 (da) 1993-07-30 2004-08-09 Aruba Internat Pty Ltd Plasmadelipidationssystem
AUPN030794A0 (en) 1994-12-22 1995-01-27 Aruba International Pty Ltd Discontinuous plasma or serum delipidation
US6034073A (en) * 1995-04-24 2000-03-07 Novavax, Inc. Solvent detergent emulsions having antiviral activity
WO1997005480A1 (en) * 1995-07-27 1997-02-13 Massachusetts Institute Of Technology Separation and/or concentration of an analyte from a mixture using a two-phase aqueous micellar system
US5741894A (en) * 1995-09-22 1998-04-21 Baxter International, Inc. Preparation of pharmaceutical grade hemoglobins by heat treatment in partially oxygenated form
US6632648B1 (en) 1996-05-14 2003-10-14 Elan Drug Delivery Limited Methods of terminal sterilization of fibrinogen
US6015832A (en) * 1997-12-31 2000-01-18 The Regents Of The University Of Michigan Methods of inactivating bacteria including bacterial spores
US6436344B1 (en) * 1999-11-02 2002-08-20 American National Red Cross Method of inactivating pathogens
CA2395435A1 (en) * 1999-12-22 2001-06-28 David B. Weiner Cosmid dna constructs and methods of making and using the same
US20090017069A1 (en) * 2000-06-29 2009-01-15 Lipid Sciences, Inc. SARS Vaccine Compositions and Methods of Making and Using Them
US7439052B2 (en) * 2000-06-29 2008-10-21 Lipid Sciences Method of making modified immunodeficiency virus particles
US7407663B2 (en) * 2000-06-29 2008-08-05 Lipid Sciences, Inc. Modified immunodeficiency virus particles
US7407662B2 (en) * 2000-06-29 2008-08-05 Lipid Sciences, Inc. Modified viral particles with immunogenic properties and reduced lipid content
AUPQ846900A0 (en) * 2000-06-29 2000-07-27 Aruba International Pty Ltd A vaccine
US7033500B2 (en) * 2001-06-25 2006-04-25 Lipid Sciences, Inc. Systems and methods using multiple solvents for the removal of lipids from fluids
EP1409108A4 (de) * 2001-06-25 2007-11-14 Lipid Sciences Inc Hohlfaserberührungssysteme zur entfernung von lipiden aus fluiden
AU2002345741B2 (en) * 2001-06-25 2007-11-15 Eli Lilly And Company Systems and methods using a solvent for the removal of lipids from fluids
US6991727B2 (en) * 2001-06-25 2006-01-31 Lipid Sciences, Inc. Hollow fiber contactor systems for removal of lipids from fluids
US20060060520A1 (en) * 2001-06-25 2006-03-23 Bomberger David C Systems and methods using a solvent for the removal of lipids from fluids
WO2003057129A1 (en) * 2001-12-28 2003-07-17 Terumo Kabushiki Kaisha Blood bag system and method of inactivating pathogenic microorganisms
EP1534243A4 (de) * 2002-08-26 2008-08-13 Lipid Sciences Inc Behandlung von alzheimer mit entlipidierten protein-teilchen
US20050208083A1 (en) * 2003-06-04 2005-09-22 Nanobio Corporation Compositions for inactivating pathogenic microorganisms, methods of making the compositons, and methods of use thereof
US7393826B2 (en) * 2003-07-03 2008-07-01 Lipid Sciences, Inc. Methods and apparatus for creating particle derivatives of HDL with reduced lipid content
US7375191B2 (en) * 2003-07-03 2008-05-20 Lipid Science, Inc. Methods and apparatus for creating particle derivatives of HDL with reduced lipid content
US6881573B2 (en) * 2003-09-12 2005-04-19 Allan L. Louderback Augmented solvent/detergent method for inactivating enveloped and non-enveloped viruses
US6960803B2 (en) * 2003-10-23 2005-11-01 Silicon Storage Technology, Inc. Landing pad for use as a contact to a conductive spacer
EP1685852A1 (de) * 2005-02-01 2006-08-02 Fondation pour la Recherche Diagnostique Set von Einwegbeuteln zur Virusinaktivierung von biologischen Fluids
EP1871349A1 (de) * 2005-04-11 2008-01-02 Nanobio Corporation Quartäre ammoniumhalogenide zur behandlung von infektionskrankheiten
WO2008051186A2 (en) * 2005-08-09 2008-05-02 Nanobio Corporation Nanoemulsion containing compositions having ant i -inflammatory activity
CH706420A1 (fr) * 2012-04-19 2013-10-31 Valerie Soulie Procédé d'inactivation virale d'un fluide biologique, dispositif et récipient pour la mise en œuvre d'un tel procédé.
KR101848830B1 (ko) 2012-09-26 2018-04-16 본 테라퓨틱스 소시에테아노님 용매/세제-처리된 혈장(s/d 혈장)을 포함하는 제형 및 그의 용도
ES2878948T3 (es) 2014-06-12 2021-11-19 Biomerieux Deutschland Gmbh Desenmascarar endotoxinas en solución
CA2951750C (en) 2014-06-12 2019-11-05 Hyglos Invest Gmbh Unmasking endotoxins in solution
CN118594035A (zh) 2017-11-22 2024-09-06 Hdl治疗公司 用于对血浆处理系统的流体回路进行灌注的系统和方法
CA3087207A1 (en) 2017-12-28 2019-07-04 Hdl Therapeutics, Inc. Methods for preserving and administering pre-beta high density lipoprotein extracted from human plasma
JP2023063147A (ja) * 2021-10-22 2023-05-09 花王株式会社 ウイルス不活化剤
KR102855613B1 (ko) * 2022-05-25 2025-09-05 김주학 신규 분리제를 이용한 다층 포장재 재활용 방법

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DE2749130A1 (de) * 1977-11-03 1979-05-10 Voigt Hans Wolfgang Dr Med Ein neues verfahren zur klaerung lipaemischer seren, plasmen und kontrollseren humanen und tierischen ursprungs
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Also Published As

Publication number Publication date
JPH01294629A (ja) 1989-11-28
DE3880292D1 (de) 1993-05-19
EP0322786B1 (de) 1993-04-14
EP0322786A2 (de) 1989-07-05
JP2742806B2 (ja) 1998-04-22
EP0322786A3 (en) 1990-05-02
US4909940A (en) 1990-03-20
KR890010193A (ko) 1989-08-07
DE3880292T2 (de) 1993-09-09

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