ATE88093T1 - Ausscheidung von prozesschemikalien aus biologischen gemischen mit halogenierten kohlenwasserstoffen. - Google Patents

Ausscheidung von prozesschemikalien aus biologischen gemischen mit halogenierten kohlenwasserstoffen.

Info

Publication number
ATE88093T1
ATE88093T1 AT88121582T AT88121582T ATE88093T1 AT E88093 T1 ATE88093 T1 AT E88093T1 AT 88121582 T AT88121582 T AT 88121582T AT 88121582 T AT88121582 T AT 88121582T AT E88093 T1 ATE88093 T1 AT E88093T1
Authority
AT
Austria
Prior art keywords
biological material
halogenated
lipid soluble
hydrocarbs
removal
Prior art date
Application number
AT88121582T
Other languages
English (en)
Inventor
Bernard Horowitz
Richard J Bonomo
Original Assignee
New York Blood Center Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New York Blood Center Inc filed Critical New York Blood Center Inc
Application granted granted Critical
Publication of ATE88093T1 publication Critical patent/ATE88093T1/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/02Recovery or purification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/647Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/16Blood plasma; Blood serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/18Erythrocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088Liquid substances
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Developmental Biology & Embryology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Extraction Or Liquid Replacement (AREA)
AT88121582T 1987-12-30 1988-12-23 Ausscheidung von prozesschemikalien aus biologischen gemischen mit halogenierten kohlenwasserstoffen. ATE88093T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/139,502 US4909940A (en) 1987-12-30 1987-12-30 Extraction of process chemicals from labile biological mixtures with organic alcohols or with halogenated hydrocarbons
EP88121582A EP0322786B1 (de) 1987-12-30 1988-12-23 Ausscheidung von Prozesschemikalien aus biologischen Gemischen mit halogenierten Kohlenwasserstoffen

Publications (1)

Publication Number Publication Date
ATE88093T1 true ATE88093T1 (de) 1993-04-15

Family

ID=22486977

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88121582T ATE88093T1 (de) 1987-12-30 1988-12-23 Ausscheidung von prozesschemikalien aus biologischen gemischen mit halogenierten kohlenwasserstoffen.

Country Status (6)

Country Link
US (1) US4909940A (de)
EP (1) EP0322786B1 (de)
JP (1) JP2742806B2 (de)
KR (1) KR890010193A (de)
AT (1) ATE88093T1 (de)
DE (1) DE3880292T2 (de)

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US5094960A (en) 1988-10-07 1992-03-10 New York Blood Center, Inc. Removal of process chemicals from labile biological mixtures by hydrophobic interaction chromatography
US5418130A (en) * 1990-04-16 1995-05-23 Cryopharm Corporation Method of inactivation of viral and bacterial blood contaminants
US6187572B1 (en) 1990-04-16 2001-02-13 Baxter International Inc. Method of inactivation of viral and bacterial blood contaminants
US5071650A (en) * 1990-06-04 1991-12-10 Miles Inc. Use of intermediate length alcohols as virucidal agents in solutions of biologically active proteins
BE1005163A3 (fr) * 1991-08-01 1993-05-11 Solvay Compositions contenant un ether fluore et utilisation de ces compositions.
DE4125625C2 (de) * 1991-08-02 1999-12-02 Octapharma Ag Glarus Verfahren zur Herstellung von virusinaktivierten Immunglobulinlösungen
EP0622989A1 (de) * 1992-05-04 1994-11-09 Edward Shanbrom Verfahren zur inaktivierung von mikroben in blut unter verwendung von jod
DE4227130A1 (de) * 1992-08-17 1994-02-24 Solvay Fluor & Derivate Zusammensetzungen aus 1-Chlor-2,2,2-trifluorethyldifluormethylether und partiell fluorierten Alkanolen
WO1995003840A1 (en) 1993-07-30 1995-02-09 The University Of Queensland A plasma delipidation system
AUPN030794A0 (en) 1994-12-22 1995-01-27 Aruba International Pty Ltd Discontinuous plasma or serum delipidation
US6034073A (en) * 1995-04-24 2000-03-07 Novavax, Inc. Solvent detergent emulsions having antiviral activity
US5772888A (en) * 1995-07-27 1998-06-30 Massachusetts Institute Of Technology Separation and/or concentration of an analyte from a mixture using a two-phase aqueous micellar system
US5741894A (en) * 1995-09-22 1998-04-21 Baxter International, Inc. Preparation of pharmaceutical grade hemoglobins by heat treatment in partially oxygenated form
US6632648B1 (en) * 1996-05-14 2003-10-14 Elan Drug Delivery Limited Methods of terminal sterilization of fibrinogen
US6015832A (en) * 1997-12-31 2000-01-18 The Regents Of The University Of Michigan Methods of inactivating bacteria including bacterial spores
US6436344B1 (en) 1999-11-02 2002-08-20 American National Red Cross Method of inactivating pathogens
EP1257298B1 (de) * 1999-12-22 2008-08-06 The Trustees Of The University Of Pennsylvania Kosmid-dns-konstrukte und verfahren für deren herstellung und verwendung
US7407662B2 (en) * 2000-06-29 2008-08-05 Lipid Sciences, Inc. Modified viral particles with immunogenic properties and reduced lipid content
US7407663B2 (en) * 2000-06-29 2008-08-05 Lipid Sciences, Inc. Modified immunodeficiency virus particles
US20090017069A1 (en) * 2000-06-29 2009-01-15 Lipid Sciences, Inc. SARS Vaccine Compositions and Methods of Making and Using Them
US7439052B2 (en) * 2000-06-29 2008-10-21 Lipid Sciences Method of making modified immunodeficiency virus particles
AUPQ846900A0 (en) * 2000-06-29 2000-07-27 Aruba International Pty Ltd A vaccine
US6991727B2 (en) 2001-06-25 2006-01-31 Lipid Sciences, Inc. Hollow fiber contactor systems for removal of lipids from fluids
US20060060520A1 (en) * 2001-06-25 2006-03-23 Bomberger David C Systems and methods using a solvent for the removal of lipids from fluids
US20030127386A1 (en) * 2001-06-25 2003-07-10 Bomberger David C. Hollow fiber contactor systems for removal of lipids from fluids
AU2002322284A1 (en) * 2001-06-25 2003-01-08 Lipid Sciences, Inc. Systems and methods using multiple solvents for the removal of lipids from fluids
CA2451633C (en) * 2001-06-25 2010-11-30 Lipid Sciences, Inc. Systems and methods using a solvent for the removal of lipids from fluids
AU2002359918A1 (en) * 2001-12-28 2003-07-24 Terumo Kabushiki Kaisha Blood bag system and method of inactivating pathogenic microorganisms
EP1534243A4 (de) * 2002-08-26 2008-08-13 Lipid Sciences Inc Behandlung von alzheimer mit entlipidierten protein-teilchen
US20050208083A1 (en) * 2003-06-04 2005-09-22 Nanobio Corporation Compositions for inactivating pathogenic microorganisms, methods of making the compositons, and methods of use thereof
JP2007527387A (ja) * 2003-07-03 2007-09-27 リピッド サイエンシーズ,インコーポレイテッド 脂質含量の低下したhdlの粒子誘導体を製造するための方法及び装置
US7393826B2 (en) * 2003-07-03 2008-07-01 Lipid Sciences, Inc. Methods and apparatus for creating particle derivatives of HDL with reduced lipid content
US6881573B2 (en) * 2003-09-12 2005-04-19 Allan L. Louderback Augmented solvent/detergent method for inactivating enveloped and non-enveloped viruses
US6960803B2 (en) * 2003-10-23 2005-11-01 Silicon Storage Technology, Inc. Landing pad for use as a contact to a conductive spacer
EP1685852A1 (de) * 2005-02-01 2006-08-02 Fondation pour la Recherche Diagnostique Set von Einwegbeuteln zur Virusinaktivierung von biologischen Fluids
WO2006110699A1 (en) * 2005-04-11 2006-10-19 Nanobio Corporation Quaternary ammonium halides for treatment of infectious conditions
WO2008051186A2 (en) * 2005-08-09 2008-05-02 Nanobio Corporation Nanoemulsion containing compositions having ant i -inflammatory activity
CH706420A1 (fr) * 2012-04-19 2013-10-31 Valerie Soulie Procédé d'inactivation virale d'un fluide biologique, dispositif et récipient pour la mise en œuvre d'un tel procédé.
ES2664694T3 (es) 2012-09-26 2018-04-23 Bone Therapeutics S.A. Composiciones que comprenden plasma tratado con solvente/detergente y ácido hialurónico para su uso en el tratamiento de trastornos musculoesqueléticos
ES2878948T3 (es) 2014-06-12 2021-11-19 Biomerieux Deutschland Gmbh Desenmascarar endotoxinas en solución
WO2015189378A1 (en) 2014-06-12 2015-12-17 Microcoat Biotechnologie Gmbh Unmasking endotoxins in solution
US11027052B2 (en) 2017-11-22 2021-06-08 HDL Therapuetics, Inc. Systems and methods for priming fluid circuits of a plasma processing system
JP2021509894A (ja) 2017-12-28 2021-04-08 エイチディーエル セラピューティクス インコーポレイテッドHdl Therapeutics, Inc. ヒト血漿から抽出されたpre−β高密度リポタンパク質を保存および投与するための方法

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BE661402A (de) * 1964-03-20
US3958939A (en) * 1975-01-08 1976-05-25 Coulter Electronics, Inc. Method for clarification of lipemic serum
DE2749130A1 (de) * 1977-11-03 1979-05-10 Voigt Hans Wolfgang Dr Med Ein neues verfahren zur klaerung lipaemischer seren, plasmen und kontrollseren humanen und tierischen ursprungs
FR2483779A1 (fr) * 1980-06-05 1981-12-11 Synthelabo Procede pour isoler des antigenes glycoproteiques viraux et son application a la preparation de vaccins
US4412985A (en) * 1980-10-06 1983-11-01 Edward Shanbrom Depyrogenation process
US4481189A (en) * 1982-04-14 1984-11-06 New York Blood Center Inc. Process for preparing sterilized plasma and plasma derivatives
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US4789545A (en) * 1986-03-31 1988-12-06 New York Blood Center, Inc. Removal of lipid soluble process chemicals from biological materials by extraction with naturally occurring oils or synthetic substitutes thereof
EP0247592B1 (de) * 1986-05-30 1992-03-04 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Sorbentmittel für beta 2-Mikroglobulin und Immunoglobulin L-Kette

Also Published As

Publication number Publication date
JPH01294629A (ja) 1989-11-28
DE3880292T2 (de) 1993-09-09
US4909940A (en) 1990-03-20
EP0322786A2 (de) 1989-07-05
KR890010193A (ko) 1989-08-07
EP0322786A3 (en) 1990-05-02
DE3880292D1 (de) 1993-05-19
JP2742806B2 (ja) 1998-04-22
EP0322786B1 (de) 1993-04-14

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