DK1419789T3 - Fremstilling af en lipidblanding og en phospholipidsuspension, indeholdende lipidblandingen, og kontrastmidler på basis af disse - Google Patents

Fremstilling af en lipidblanding og en phospholipidsuspension, indeholdende lipidblandingen, og kontrastmidler på basis af disse

Info

Publication number
DK1419789T3
DK1419789T3 DK04075388.1T DK04075388T DK1419789T3 DK 1419789 T3 DK1419789 T3 DK 1419789T3 DK 04075388 T DK04075388 T DK 04075388T DK 1419789 T3 DK1419789 T3 DK 1419789T3
Authority
DK
Denmark
Prior art keywords
lipid blend
preparation
contrast agents
phospholipid suspension
lipid
Prior art date
Application number
DK04075388.1T
Other languages
English (en)
Inventor
Poh K Hui
John E Bishop
Eleodoro S Madrigal Jr
Original Assignee
Lantheus Medical Imaging Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lantheus Medical Imaging Inc filed Critical Lantheus Medical Imaging Inc
Application granted granted Critical
Publication of DK1419789T3 publication Critical patent/DK1419789T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/226—Solutes, emulsions, suspensions, dispersions, semi-solid forms, e.g. hydrogels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/227—Liposomes, lipoprotein vesicles, e.g. LDL or HDL lipoproteins, micelles, e.g. phospholipidic or polymeric
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Acoustics & Sound (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK04075388.1T 1998-01-14 1999-01-14 Fremstilling af en lipidblanding og en phospholipidsuspension, indeholdende lipidblandingen, og kontrastmidler på basis af disse DK1419789T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7133298P 1998-01-14 1998-01-14
EP99901466A EP1027035A2 (en) 1998-01-14 1999-01-14 Preparation of a lipid blend and a phospholipid suspension containing the lipid blend, and contrast agents based on these

Publications (1)

Publication Number Publication Date
DK1419789T3 true DK1419789T3 (da) 2010-03-29

Family

ID=22100659

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04075388.1T DK1419789T3 (da) 1998-01-14 1999-01-14 Fremstilling af en lipidblanding og en phospholipidsuspension, indeholdende lipidblandingen, og kontrastmidler på basis af disse

Country Status (31)

Country Link
US (8) US20010003580A1 (da)
EP (2) EP1419789B1 (da)
JP (2) JP5160702B2 (da)
KR (1) KR100711663B1 (da)
CN (1) CN1191822C (da)
AR (1) AR016444A1 (da)
AT (1) ATE447976T1 (da)
AU (1) AU746067C (da)
BR (1) BR9907066A (da)
CA (1) CA2317921C (da)
DE (1) DE69941634D1 (da)
DK (1) DK1419789T3 (da)
EA (1) EA002978B1 (da)
EE (1) EE04900B1 (da)
ES (1) ES2336669T3 (da)
HK (1) HK1064301A1 (da)
HR (1) HRP990012A2 (da)
HU (1) HUP0100206A3 (da)
IL (2) IL137018A0 (da)
MY (1) MY137255A (da)
NO (1) NO321866B1 (da)
NZ (1) NZ505082A (da)
PH (1) PH12012000094A1 (da)
PL (1) PL193672B1 (da)
PT (1) PT1419789E (da)
SI (1) SI1419789T1 (da)
SK (1) SK285333B6 (da)
TW (1) TWI242448B (da)
UA (1) UA75023C2 (da)
WO (1) WO1999036104A2 (da)
ZA (1) ZA99247B (da)

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US20010003580A1 (en) 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
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US20030049158A1 (en) * 2001-04-03 2003-03-13 Hui Poh K. Stablization and terminal sterilization of phospholipid formulations
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US9364569B2 (en) * 2003-02-04 2016-06-14 Bracco Suisse S.A. Ultrasound contrast agents and process for the preparation thereof
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US7858115B2 (en) * 2004-06-24 2010-12-28 Idexx Laboratories Phospholipid gel compositions for drug delivery and methods of treating conditions using same
US7618651B2 (en) 2004-06-24 2009-11-17 Idexx Laboratories Pharmaceutical compositions for drug delivery and methods of treating or preventing conditions using same
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JP5771366B2 (ja) * 2009-09-02 2015-08-26 株式会社バイオメッドコア リポソーム製造装置及び方法
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CN107206111B (zh) 2014-12-31 2021-04-27 蓝瑟斯医学影像公司 脂质封装的气体微球组合物及相关方法
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RU2745290C2 (ru) * 2019-04-12 2021-03-23 Ирина Николаевна Кузнецова Эмульсия перфторуглеродных соединений медико-биологического назначения и способ её получения
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PL342473A1 (en) 2001-06-04
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CA2317921A1 (en) 1999-07-22
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ATE447976T1 (de) 2009-11-15
NO321866B1 (no) 2006-07-17
ZA99247B (en) 2000-07-14
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US20150023880A1 (en) 2015-01-22
PT1419789E (pt) 2010-02-17
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