AU6974798A - Novel prodrugs comprising fluorinated amphiphiles - Google Patents

Novel prodrugs comprising fluorinated amphiphiles

Info

Publication number
AU6974798A
AU6974798A AU69747/98A AU6974798A AU6974798A AU 6974798 A AU6974798 A AU 6974798A AU 69747/98 A AU69747/98 A AU 69747/98A AU 6974798 A AU6974798 A AU 6974798A AU 6974798 A AU6974798 A AU 6974798A
Authority
AU
Australia
Prior art keywords
novel prodrugs
fluorinated amphiphiles
amphiphiles
fluorinated
prodrugs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU69747/98A
Inventor
Evan C. Unger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ImaRx Pharmaceutical Corp
Original Assignee
ImaRx Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/851,780 external-priority patent/US6090800A/en
Application filed by ImaRx Pharmaceutical Corp filed Critical ImaRx Pharmaceutical Corp
Publication of AU6974798A publication Critical patent/AU6974798A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0028—Disruption, e.g. by heat or ultrasounds, sonophysical or sonochemical activation, e.g. thermosensitive or heat-sensitive liposomes, disruption of calculi with a medicinal preparation and ultrasounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
    • A61K47/544—Phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acoustics & Sound (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
AU69747/98A 1997-05-06 1998-04-15 Novel prodrugs comprising fluorinated amphiphiles Abandoned AU6974798A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08/851,780 US6090800A (en) 1997-05-06 1997-05-06 Lipid soluble steroid prodrugs
US08851780 1997-05-06
US08/887,215 US6028066A (en) 1997-05-06 1997-07-02 Prodrugs comprising fluorinated amphiphiles
US08887215 1997-07-02
PCT/US1998/007712 WO1998050041A1 (en) 1997-05-06 1998-04-15 Novel prodrugs comprising fluorinated amphiphiles

Publications (1)

Publication Number Publication Date
AU6974798A true AU6974798A (en) 1998-11-27

Family

ID=27127023

Family Applications (1)

Application Number Title Priority Date Filing Date
AU69747/98A Abandoned AU6974798A (en) 1997-05-06 1998-04-15 Novel prodrugs comprising fluorinated amphiphiles

Country Status (2)

Country Link
AU (1) AU6974798A (en)
WO (1) WO1998050041A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010003580A1 (en) 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
PT1955700E (en) 1999-09-30 2011-05-04 Harbor Biosciences Inc Therapeutic treatment of androgen receptor driven conditions
DK1347743T3 (en) 2000-12-07 2006-07-03 Univ Utrecht Holding Bv Preparation for the treatment of inflammatory disorders
US7887835B2 (en) * 2006-09-19 2011-02-15 Fujifilm Corporation Compound comprising a fluorine-substituted alkyl group and a liposome contrast medium comprising the compound
US20100286250A1 (en) * 2007-09-26 2010-11-11 Tufts University Fluorinated lipids and methods of use
RU2703416C2 (en) * 2014-03-28 2019-10-16 Эпосенс Лтд. Compounds for trans-membrane delivery of molecules
US9993563B2 (en) 2014-03-28 2018-06-12 Aposense Ltd. Compounds and methods for trans-membrane delivery of molecules
US9889202B2 (en) 2014-03-28 2018-02-13 Aposense Ltd. Compounds and methods for trans-membrane delivery of molecules
US11318206B2 (en) 2014-03-28 2022-05-03 Aposense Ltd Compounds and methods for trans-membrane delivery of molecules
CA3049640A1 (en) 2017-01-09 2018-07-12 Aposense Ltd. Compounds and methods for trans-membrane delivery of molecules
CN108912245B (en) * 2018-07-13 2020-04-28 吉林大学 Fluorinated hyaluronic acid derivative with targeting and anti-inflammatory activities and preparation method and application thereof
CN109030838A (en) * 2018-10-11 2018-12-18 北京工商大学 It is a kind of for detecting the colloid gold test paper of dexamethasone
CN112047804B (en) * 2020-09-10 2023-06-27 内蒙古永太化学有限公司 Preparation method of 3, 5-dichloro-4-fluorobromobenzene compound

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8403905D0 (en) * 1984-07-30 1984-07-30 Draco Ab LIPOSOMES AND STEROID ESTERS
CA1326662C (en) * 1988-03-09 1994-02-01 Yutaka Mizushima 11.beta.,17.,21-trihydroxy-1,4-pregnadiene-3,20-dione 21-[(e,e)-3,7,11-trimethyl-2,6,10-dodecatrienoate]

Also Published As

Publication number Publication date
WO1998050041A1 (en) 1998-11-12

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase