HK1057538A1 - 3,4-Di-substituted cyclobutene-1,2-diones as cxc-chemokine receptor ligands - Google Patents

3,4-Di-substituted cyclobutene-1,2-diones as cxc-chemokine receptor ligands

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Publication number
HK1057538A1
HK1057538A1 HK04100477A HK04100477A HK1057538A1 HK 1057538 A1 HK1057538 A1 HK 1057538A1 HK 04100477 A HK04100477 A HK 04100477A HK 04100477 A HK04100477 A HK 04100477A HK 1057538 A1 HK1057538 A1 HK 1057538A1
Authority
HK
Hong Kong
Prior art keywords
cxc
diones
chemokine receptor
receptor ligands
substituted cyclobutene
Prior art date
Application number
HK04100477A
Other languages
English (en)
Inventor
Arthur G Taveras
Cynthia J Aki
Richard W Bond
Jianping Cao
Michael Dwyer
Johan A Ferreira
Jianhua Chao
Younong Yu
John J Baldwin
Bernd Kaiser
Ge Li
J Robert Merritt
Kingsley H Nelson
Laura L Rokosz
Original Assignee
Pharmacopeia Drug Discovery
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacopeia Drug Discovery, Schering Corp filed Critical Pharmacopeia Drug Discovery
Publication of HK1057538A1 publication Critical patent/HK1057538A1/xx

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Neurology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
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  • Hematology (AREA)
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  • Diabetes (AREA)
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HK04100477A 2001-04-16 2004-01-21 3,4-Di-substituted cyclobutene-1,2-diones as cxc-chemokine receptor ligands HK1057538A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28402601P 2001-04-16 2001-04-16
PCT/US2002/012681 WO2002083624A1 (en) 2001-04-16 2002-04-15 3,4-di-substituted cyclobutene-1,2-diones as cxc-chemokine receptor ligands

Publications (1)

Publication Number Publication Date
HK1057538A1 true HK1057538A1 (en) 2004-04-08

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ID=23088576

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Application Number Title Priority Date Filing Date
HK04100477A HK1057538A1 (en) 2001-04-16 2004-01-21 3,4-Di-substituted cyclobutene-1,2-diones as cxc-chemokine receptor ligands
HK08101594.0A HK1107818A1 (en) 2001-04-16 2008-02-13 3,4-di-substituted cyclobutene-1,2-diones as cxc-chemokine receptor ligands

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HK08101594.0A HK1107818A1 (en) 2001-04-16 2008-02-13 3,4-di-substituted cyclobutene-1,2-diones as cxc-chemokine receptor ligands

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EP (2) EP1818325B1 (xx)
JP (3) JP4499993B2 (xx)
KR (2) KR20100008794A (xx)
CN (2) CN1289471C (xx)
AR (1) AR035825A1 (xx)
AT (2) ATE365154T1 (xx)
AU (3) AU2002311841B2 (xx)
BR (1) BRPI0208957B8 (xx)
CA (1) CA2444031C (xx)
CY (2) CY1109908T1 (xx)
CZ (1) CZ20032831A3 (xx)
DE (2) DE60220778T2 (xx)
DK (2) DK1818325T3 (xx)
EC (1) ECSP034809A (xx)
ES (2) ES2340207T3 (xx)
HK (2) HK1057538A1 (xx)
HU (1) HUP0401783A3 (xx)
IL (3) IL158262A0 (xx)
MX (1) MXPA03009441A (xx)
MY (2) MY138202A (xx)
NO (2) NO330790B1 (xx)
NZ (3) NZ529551A (xx)
PE (1) PE20021084A1 (xx)
PL (2) PL207255B1 (xx)
PT (2) PT1818325E (xx)
RU (1) RU2344123C9 (xx)
SI (2) SI1818325T1 (xx)
SK (1) SK287598B6 (xx)
TW (2) TW200736196A (xx)
WO (1) WO2002083624A1 (xx)
ZA (1) ZA200307905B (xx)

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WO2005012256A1 (en) 2003-07-22 2005-02-10 Astex Therapeutics Limited 3, 4-disubstituted 1h-pyrazole compounds and their use as cyclin dependent kinases (cdk) and glycogen synthase kinase-3 (gsk-3) modulators
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