GT201300102A - Dispersiones solidas extruidas por fusion que contienen un agente inductor de apoptosis - Google Patents

Dispersiones solidas extruidas por fusion que contienen un agente inductor de apoptosis

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Publication number
GT201300102A
GT201300102A GT201300102A GT201300102A GT201300102A GT 201300102 A GT201300102 A GT 201300102A GT 201300102 A GT201300102 A GT 201300102A GT 201300102 A GT201300102 A GT 201300102A GT 201300102 A GT201300102 A GT 201300102A
Authority
GT
Guatemala
Prior art keywords
extruded
solid dispersions
inductive agent
fusion containing
apoptosis
Prior art date
Application number
GT201300102A
Other languages
English (en)
Inventor
Esther Rosch
Peter Hoelig
David J Lindley
Yeshwant D Sanzgiri
Ping Tong
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44903438&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GT201300102(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of GT201300102A publication Critical patent/GT201300102A/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
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    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
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    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
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    • A61K9/20—Pills, tablets, discs, rods
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    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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  • Chemical Kinetics & Catalysis (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Biophysics (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

LA PRESENTE INVENCIÓN SE RELACIONA CON DISPERSIONES SÓLIDAS QUE COMPRENDEN UN AGENTE INDUCTOR DE APOPTOSIS, CON FORMAS DE DOSIFICACIÓN FARMACÉUTICAS QUE COMPRENDEN DICHAS DISPERSIONES, CON PROCESOS PARA PREPARAR DICHAS DISPERSIONES Y FORMAS DE DOSIFICACIÓN Y CON MÉTODOS DE USO DE LAS MISMAS PARA TRATAR ENFERMEDADES CARACTERIZADAS POR LA SOBREEXPRESIÓN DE PROTEÍNAS ANTI-APOPTÓTICAS DE LA FAMILIA BCL-2
GT201300102A 2010-10-29 2013-04-22 Dispersiones solidas extruidas por fusion que contienen un agente inductor de apoptosis GT201300102A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40852710P 2010-10-29 2010-10-29

Publications (1)

Publication Number Publication Date
GT201300102A true GT201300102A (es) 2014-05-20

Family

ID=44903438

Family Applications (1)

Application Number Title Priority Date Filing Date
GT201300102A GT201300102A (es) 2010-10-29 2013-04-22 Dispersiones solidas extruidas por fusion que contienen un agente inductor de apoptosis

Country Status (40)

Country Link
US (2) US20120108590A1 (es)
EP (3) EP2613769B1 (es)
JP (2) JP5902187B2 (es)
KR (2) KR101957137B1 (es)
CN (2) CN103282025B (es)
AR (2) AR083656A1 (es)
AU (1) AU2011361704B2 (es)
BR (1) BR112013010524A8 (es)
CA (1) CA2813985C (es)
CL (1) CL2013001120A1 (es)
CO (1) CO6781472A2 (es)
CR (2) CR20180289A (es)
CY (1) CY1119993T1 (es)
DK (1) DK2613769T3 (es)
DO (2) DOP2013000092A (es)
EC (2) ECSP13012647A (es)
ES (1) ES2647583T3 (es)
GT (1) GT201300102A (es)
HK (1) HK1243761A1 (es)
HR (1) HRP20171884T1 (es)
HU (1) HUE035169T2 (es)
IL (2) IL226215A (es)
LT (1) LT2613769T (es)
ME (1) ME02942B (es)
MX (2) MX345603B (es)
MY (1) MY189224A (es)
NO (1) NO2613769T3 (es)
NZ (1) NZ608907A (es)
PE (2) PE20171242A1 (es)
PL (1) PL2613769T3 (es)
PT (1) PT2613769T (es)
RS (1) RS56718B1 (es)
RU (2) RU2633353C1 (es)
SG (2) SG189477A1 (es)
SI (1) SI2613769T1 (es)
TW (2) TWI648261B (es)
UA (1) UA113500C2 (es)
UY (3) UY39192A (es)
WO (1) WO2012121758A1 (es)
ZA (2) ZA201302669B (es)

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