GR852890B - - Google Patents

Info

Publication number
GR852890B
GR852890B GR852890A GR850102890A GR852890B GR 852890 B GR852890 B GR 852890B GR 852890 A GR852890 A GR 852890A GR 850102890 A GR850102890 A GR 850102890A GR 852890 B GR852890 B GR 852890B
Authority
GR
Greece
Prior art keywords
human epo
plasmid
recombinant
vector
atcc
Prior art date
Application number
GR852890A
Other languages
English (en)
Inventor
Edward Fritsch
Rodney M Hewick
Kenneth Jacobs
Randal J Kaufman
Original Assignee
Genetics Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27418329&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GR852890(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genetics Inst filed Critical Genetics Inst
Publication of GR852890B publication Critical patent/GR852890B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/10—Plasmid DNA
    • C12N2800/108—Plasmid DNA episomal vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/42—Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/60—Vector systems having a special element relevant for transcription from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor
GR852890A 1984-12-04 1985-12-02 GR852890B (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US67781384A 1984-12-04 1984-12-04
US68862285A 1985-01-03 1985-01-03
US69325885A 1985-01-22 1985-01-22

Publications (1)

Publication Number Publication Date
GR852890B true GR852890B (el) 1986-04-03

Family

ID=27418329

Family Applications (1)

Application Number Title Priority Date Filing Date
GR852890A GR852890B (el) 1984-12-04 1985-12-02

Country Status (24)

Country Link
EP (2) EP0205564B2 (el)
JP (4) JPH0655144B2 (el)
KR (1) KR890001011B1 (el)
AT (2) ATE71408T1 (el)
AU (1) AU621535B2 (el)
CA (1) CA1341502C (el)
CZ (3) CZ281756B6 (el)
DE (3) DE411678T1 (el)
DK (4) DK172953B1 (el)
ES (1) ES8800049A1 (el)
FI (2) FI104261B1 (el)
GE (1) GEP19970775B (el)
GR (1) GR852890B (el)
HK (2) HK105693A (el)
HU (1) HU216079B (el)
IL (1) IL77081A (el)
LV (2) LV10505B (el)
MD (1) MD1639C2 (el)
NO (1) NO304469B1 (el)
PL (2) PL154180B1 (el)
PT (1) PT81590B (el)
SK (2) SK279765B6 (el)
UA (1) UA44882C2 (el)
WO (1) WO1986003520A1 (el)

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US4954437A (en) * 1986-09-15 1990-09-04 Integrated Genetics, Inc. Cell encoding recombinant human erythropoietin
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US5888774A (en) * 1994-12-19 1999-03-30 Cangene Corporation Recombinant DNA molecules and expression vectors for erythropoietin
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Also Published As

Publication number Publication date
ES8800049A1 (es) 1987-10-16
CZ880485A3 (en) 1996-08-14
FI863044A (fi) 1986-07-24
DK173254B1 (da) 2000-05-22
ES549539A0 (es) 1987-10-16
HK105693A (en) 1993-10-15
EP0411678B2 (en) 2000-01-12
EP0205564B2 (en) 2000-06-21
GEP19970775B (en) 1997-01-27
CA1341502C (en) 2006-03-21
SK281799B6 (sk) 2001-08-06
NO863050D0 (no) 1986-07-28
DK172953B1 (da) 1999-10-18
CZ281756B6 (cs) 1997-01-15
AU5313486A (en) 1986-07-01
HU216079B (hu) 1999-04-28
PL154180B1 (en) 1991-07-31
DK173293B1 (da) 2000-06-13
MD1639C2 (ro) 2001-10-31
DE3582732D1 (de) 1991-06-06
JPH07184681A (ja) 1995-07-25
PL157926B1 (pl) 1992-07-31
MD940371A (en) 1996-06-28
NO304469B1 (no) 1998-12-21
LV10505B (en) 1996-04-20
CZ287620B6 (cs) 2001-01-17
IL77081A0 (en) 1986-04-29
LV10505A (lv) 1995-02-20
DK368786A (da) 1986-08-01
DK200000527A (da) 2000-03-29
DE411678T1 (de) 1991-10-17
JPH0655144B2 (ja) 1994-07-27
DK95197A (da) 1997-08-20
DK175826B1 (da) 2005-03-14
JPH02442A (ja) 1990-01-05
KR890001011B1 (en) 1989-04-18
SK279765B6 (sk) 1999-03-12
MD1639B2 (en) 2001-03-31
FI105347B (fi) 2000-07-31
DK199901147A (da) 1999-08-20
CZ127496A3 (cs) 2000-02-16
LV10507B (lv) 1996-06-20
EP0411678A1 (en) 1991-02-06
EP0411678B1 (en) 1992-01-08
ATE71408T1 (de) 1992-01-15
CZ286557B6 (cs) 2000-05-17
WO1986003520A1 (en) 1986-06-19
IL77081A (en) 1999-10-28
DE3585161D1 (de) 1992-02-20
PL256589A1 (en) 1986-10-21
HK105593A (en) 1993-10-15
JPH02104284A (ja) 1990-04-17
AU621535B2 (en) 1992-03-19
UA44882C2 (uk) 2002-03-15
FI104261B (fi) 1999-12-15
ATE63137T1 (de) 1991-05-15
EP0205564A1 (en) 1986-12-30
JPH01257480A (ja) 1989-10-13
PT81590B (pt) 1987-10-20
FI104261B1 (fi) 1999-12-15
LV10507A (lv) 1995-02-20
EP0205564A4 (en) 1987-12-14
SK880485A3 (en) 1999-03-10
NO863050L (no) 1986-07-28
EP0205564B1 (en) 1991-05-02
FI19992064A (fi) 1999-09-27
SK168799A3 (en) 2001-08-06
DK368786D0 (da) 1986-08-01
PT81590A (en) 1986-01-01
FI863044A0 (fi) 1986-07-24
HUT40706A (en) 1987-01-28
KR870700099A (ko) 1987-02-28

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