GB9913083D0 - Organic compounds - Google Patents

Organic compounds

Info

Publication number
GB9913083D0
GB9913083D0 GBGB9913083.3A GB9913083A GB9913083D0 GB 9913083 D0 GB9913083 D0 GB 9913083D0 GB 9913083 A GB9913083 A GB 9913083A GB 9913083 D0 GB9913083 D0 GB 9913083D0
Authority
GB
United Kingdom
Prior art keywords
organic compounds
compounds
organic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB9913083.3A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10854788&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GB9913083(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Priority to GBGB9913083.3A priority Critical patent/GB9913083D0/en
Publication of GB9913083D0 publication Critical patent/GB9913083D0/en
Priority to TW089108928A priority patent/TWI253447B/zh
Priority to MYPI20002328A priority patent/MY126951A/en
Priority to CO00039577A priority patent/CO5170518A1/es
Priority to ARP000102709A priority patent/AR035548A1/es
Priority to PT81715237T priority patent/PT2332915E/pt
Priority to AU50745/00A priority patent/AU765919B2/en
Priority to RU2001135801/04A priority patent/RU2244709C2/ru
Priority to DK08171523.7T priority patent/DK2332915T3/da
Priority to PCT/EP2000/005058 priority patent/WO2000075114A1/en
Priority to BRPI0011324A priority patent/BRPI0011324B8/pt
Priority to DE201012000009 priority patent/DE122010000009I2/de
Priority to PT00935163T priority patent/PT1183240E/pt
Priority to AT00935163T priority patent/ATE440083T1/de
Priority to PL352100A priority patent/PL198847B1/pl
Priority to SK1743-2001A priority patent/SK287260B6/sk
Priority to DK00935163T priority patent/DK1183240T3/da
Priority to EP00935163A priority patent/EP1183240B1/en
Priority to JP2001501595A priority patent/JP3785365B2/ja
Priority to ES00935163T priority patent/ES2331457T3/es
Priority to CA2375810A priority patent/CA2375810C/en
Priority to SI200031045T priority patent/SI1183240T1/sl
Priority to CNB008084874A priority patent/CN1156451C/zh
Priority to MXPA01012474A priority patent/MXPA01012474A/es
Priority to ES08171523T priority patent/ES2402535T3/es
Priority to CZ20014301A priority patent/CZ302403B6/cs
Priority to TR2001/03497T priority patent/TR200103497T2/xx
Priority to PE2000000548A priority patent/PE20010219A1/es
Priority to KR1020017015568A priority patent/KR100718615B1/ko
Priority to US10/009,008 priority patent/US6878721B1/en
Priority to EP08171523A priority patent/EP2332915B1/en
Priority to IL14657800A priority patent/IL146578A0/xx
Priority to HK02105569.8A priority patent/HK1045837B/en
Priority to DE60042781T priority patent/DE60042781D1/de
Priority to NZ515669A priority patent/NZ515669A/xx
Priority to HU0201658A priority patent/HU227034B1/hu
Priority to IL146578A priority patent/IL146578A/en
Priority to NO20015912A priority patent/NO322944B1/no
Priority to ZA200109931A priority patent/ZA200109931B/en
Priority to US11/074,400 priority patent/US7622483B2/en
Priority to US12/577,855 priority patent/US7820694B2/en
Priority to CY20091101179T priority patent/CY1109604T1/el
Priority to FR10C0006C priority patent/FR10C0006I2/fr
Priority to LU91651C priority patent/LU91651I2/fr
Priority to NL300437C priority patent/NL300437I1/nl
Priority to BE2010C011C priority patent/BE2010C011I2/fr
Priority to CY2010003C priority patent/CY2010003I2/el
Priority to NO2010014C priority patent/NO2010014I1/no
Priority to US12/885,922 priority patent/US8067437B2/en
Priority to HK11108894.7A priority patent/HK1154584B/en
Priority to US13/295,426 priority patent/US8283362B2/en
Priority to US13/555,536 priority patent/US8436017B2/en
Priority to US13/858,308 priority patent/US8658673B2/en
Priority to CY20131100413T priority patent/CY1114120T1/el
Priority to US14/076,478 priority patent/US8796307B2/en
Priority to US14/450,692 priority patent/US9040559B2/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/74—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C215/76—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton of the same non-condensed six-membered aromatic ring
    • C07C215/80—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton of the same non-condensed six-membered aromatic ring containing at least two amino groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/42—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/43—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Reproductive Health (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Otolaryngology (AREA)
  • Pain & Pain Management (AREA)
  • Pregnancy & Childbirth (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Quinoline Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
GBGB9913083.3A 1999-04-06 1999-06-04 Organic compounds Ceased GB9913083D0 (en)

Priority Applications (56)

Application Number Priority Date Filing Date Title
GBGB9913083.3A GB9913083D0 (en) 1999-06-04 1999-06-04 Organic compounds
TW089108928A TWI253447B (en) 1999-06-04 2000-05-10 Phenylethanolamine derivatives having beta2 agonist activity
MYPI20002328A MY126951A (en) 1999-06-04 2000-05-26 Beta2-adrenoceptor agonists
CO00039577A CO5170518A1 (es) 1999-06-04 2000-05-29 Compuestos n-(benzocicloalquilo) derivados de amino aralifaticos
ARP000102709A AR035548A1 (es) 1999-06-04 2000-06-01 Compuestos organicos
PT81715237T PT2332915E (pt) 1999-06-04 2000-06-02 Agonistas de adreno-receptores beta2
AU50745/00A AU765919B2 (en) 1999-06-04 2000-06-02 Beta2-adrenoceptor agonists
RU2001135801/04A RU2244709C2 (ru) 1999-06-04 2000-06-02 Соединения, способ получения соединения, фармацевтическая композиция
DK08171523.7T DK2332915T3 (da) 1999-06-04 2000-06-02 beta2-Adrenoceptoragonister
PCT/EP2000/005058 WO2000075114A1 (en) 1999-06-04 2000-06-02 Beta2-adrenoceptor agonists
BRPI0011324A BRPI0011324B8 (pt) 1999-06-04 2000-06-02 agonistas de adrenoceptores beta 2, processo de preparação dos mesmos, seu uso e composição farmacêutica compreendendo os mesmos
DE201012000009 DE122010000009I2 (de) 1999-06-04 2000-06-02 Beta2-adrenoceptor agonisten.
PT00935163T PT1183240E (pt) 1999-06-04 2000-06-02 Agonistas de adreno-receptores beta2
AT00935163T ATE440083T1 (de) 1999-06-04 2000-06-02 Beta2-adrenoceptor agonisten
PL352100A PL198847B1 (pl) 1999-06-04 2000-06-02 Agoniści receptora ß₂-adrenergicznego, kompozycje zawierające takie związki, zastosowanie agonistów receptora ß₂-adrenergicznego i sposób ich wytwarzania
SK1743-2001A SK287260B6 (sk) 1999-06-04 2000-06-02 Agonisty beta-2-adrenoreceptorov, spôsob ich prípravy, ich použitie a farmaceutický prostriedok s ich obsahom
DK00935163T DK1183240T3 (da) 1999-06-04 2000-06-02 Beta-2-adrenoceptoragonister
EP00935163A EP1183240B1 (en) 1999-06-04 2000-06-02 Beta2-adrenoceptor agonists
JP2001501595A JP3785365B2 (ja) 1999-06-04 2000-06-02 ベータ２アドレナリン受容体アゴニスト
ES00935163T ES2331457T3 (es) 1999-06-04 2000-06-02 Agonistas de beta2-adrenoceptor.
CA2375810A CA2375810C (en) 1999-06-04 2000-06-02 Beta2-adrenoceptor agonists
SI200031045T SI1183240T1 (sl) 1999-06-04 2000-06-02 Beta2-adrenoceptorski agonisti
CNB008084874A CN1156451C (zh) 1999-06-04 2000-06-02 β2-肾上腺受体激动剂
MXPA01012474A MXPA01012474A (es) 1999-06-04 2000-06-02 Agonistas del adrenoceptor beta-2.
ES08171523T ES2402535T3 (es) 1999-06-04 2000-06-02 Agonista del Beta2-adrenoceptor
CZ20014301A CZ302403B6 (cs) 1999-06-04 2000-06-02 Agonisté beta-2-adrenoceptoru
TR2001/03497T TR200103497T2 (tr) 1999-06-04 2000-06-02 Beta2-adrenoseptör agonistler.
PE2000000548A PE20010219A1 (es) 1999-06-04 2000-06-02 AGONISTAS ß-ADRENORRECEPTORES
KR1020017015568A KR100718615B1 (ko) 1999-06-04 2000-06-02 베타２-아드레날린성 촉진제
US10/009,008 US6878721B1 (en) 1999-06-04 2000-06-02 Beta2-adrenoceptor agonists
EP08171523A EP2332915B1 (en) 1999-06-04 2000-06-02 Beta2-adrenoceptor agonists
IL14657800A IL146578A0 (en) 1999-06-04 2000-06-02 Beta 2 adrenoceptor agonists
HK02105569.8A HK1045837B (en) 1999-06-04 2000-06-02 Beta2-adrenoceptor agonists
DE60042781T DE60042781D1 (de) 1999-06-04 2000-06-02 Beta2-adrenoceptor agonisten
NZ515669A NZ515669A (en) 1999-06-04 2000-06-02 Beta 2 adrenoceptor agonists
HU0201658A HU227034B1 (en) 1999-06-04 2000-06-02 Beta2-adrenoceptor agonists
IL146578A IL146578A (en) 1999-06-04 2001-11-19 Beta-2 adrenoceptor agonists
NO20015912A NO322944B1 (no) 1999-06-04 2001-12-03 Beta 2-adrenoceptoragonister, fremgangsmate for fremstilling derav, anvendelse av forbindelsene, farmasoytisk preparat omfattende disse samt mellomprodukt.
ZA200109931A ZA200109931B (en) 1999-06-04 2001-12-03 Beta2-adrenoceptor agonists.
US11/074,400 US7622483B2 (en) 1999-06-04 2005-03-07 β2-adrenoceptor agonists
US12/577,855 US7820694B2 (en) 1999-06-04 2009-10-13 Beta-2-adrenoreceptor agonists
CY20091101179T CY1109604T1 (el) 1999-06-04 2009-11-11 Αγωνιστες των βητα-2αδρενεργικων υποδοχεων
FR10C0006C FR10C0006I2 (fr) 1999-06-04 2010-02-15 Agonistes du recepteur beta 2-adrenergique
LU91651C LU91651I2 (fr) 1999-06-04 2010-02-17 Produits médicinaux contenent de l'indacatérol ou un sel de celui-ci (ONBREZ BREEZHALER®)
NL300437C NL300437I1 (nl) 1999-06-04 2010-02-18 Beta2-adrenoceptor agonists.
BE2010C011C BE2010C011I2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1999-06-04 2010-02-24
CY2010003C CY2010003I2 (el) 1999-06-04 2010-03-09 Αγωνιστες των βητα-2 αδρενεργικων υποδοχεων
NO2010014C NO2010014I1 (no) 1999-06-04 2010-07-02 Indakaterol eller et salt derav,(R)-5-[5/6-dietyl-indan-2-ylamino-l-hydroksyetyl]-8-hydroksy-LH-i kinolin-2-on
US12/885,922 US8067437B2 (en) 1999-06-04 2010-09-20 Beta-2-adrenoreceptor agonists
HK11108894.7A HK1154584B (en) 1999-06-04 2011-08-23 Beta2-adrenoceptor agonists
US13/295,426 US8283362B2 (en) 1999-06-04 2011-11-14 Beta-2-adrenoreceptor agonists
US13/555,536 US8436017B2 (en) 1999-06-04 2012-07-23 Beta-2-adrenoreceptor agonists
US13/858,308 US8658673B2 (en) 1999-04-06 2013-04-08 BETA2-adrenoreceptor agonists
CY20131100413T CY1114120T1 (el) 1999-06-04 2013-05-24 Αγωνιστες των βητα-2αδρενεργικων υποδοχεων
US14/076,478 US8796307B2 (en) 1999-04-06 2013-11-11 Beta2-adrenoreceptor agonists
US14/450,692 US9040559B2 (en) 1999-04-06 2014-08-04 BETA2-adrenoceptor agonists

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9913083.3A GB9913083D0 (en) 1999-06-04 1999-06-04 Organic compounds

Publications (1)

Publication Number Publication Date
GB9913083D0 true GB9913083D0 (en) 1999-08-04

Family

ID=10854788

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB9913083.3A Ceased GB9913083D0 (en) 1999-04-06 1999-06-04 Organic compounds

Country Status (38)

Country Link
US (9) US6878721B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (2) EP1183240B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP3785365B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR100718615B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1156451C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (1) AR035548A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE440083T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU765919B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE2010C011I2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BRPI0011324B8 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2375810C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CO (1) CO5170518A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CY (3) CY1109604T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CZ (1) CZ302403B6 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (2) DE122010000009I2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (2) DK2332915T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (2) ES2402535T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR10C0006I2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB9913083D0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HK (1) HK1045837B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU227034B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (2) IL146578A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
LU (1) LU91651I2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MX (1) MXPA01012474A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MY (1) MY126951A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL300437I1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (2) NO322944B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ515669A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PE (1) PE20010219A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL198847B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (2) PT1183240E (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RU (1) RU2244709C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SI (1) SI1183240T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SK (1) SK287260B6 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TR (1) TR200103497T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TWI253447B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO2000075114A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA200109931B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (181)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR028948A1 (es) 2000-06-20 2003-05-28 Astrazeneca Ab Compuestos novedosos
GB0029562D0 (en) 2000-12-04 2001-01-17 Novartis Ag Organic compounds
TWI243164B (en) 2001-02-13 2005-11-11 Aventis Pharma Gmbh Acylated indanyl amines and their use as pharmaceuticals
GB0121214D0 (en) * 2001-08-31 2001-10-24 Btg Int Ltd Synthetic method
WO2003042160A1 (en) 2001-11-13 2003-05-22 Theravance, Inc. Aryl aniline beta-2 adrenergic receptor agonists
TWI249515B (en) 2001-11-13 2006-02-21 Theravance Inc Aryl aniline beta2 adrenergic receptor agonists
EP2311818B1 (en) 2002-02-28 2013-01-16 Novartis AG Combination of a 5-phenylthiazole compound as PI3 kinase inhibitor with an antiinflammatory, bronchodilatory or antihistamine drug
US6933410B2 (en) 2002-03-08 2005-08-23 Novartis Ag Process for preparing 5,6-diethyl-2,3-dihydro-1H-inden-2-amine
DE10256080A1 (de) * 2002-11-29 2004-06-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Tiotropiumhaltige Arzneimittelkombination für die Inhalation
US7250426B2 (en) * 2002-11-29 2007-07-31 Boehringer Ingelheim Pharma Gmbh & Co Kg Tiotropium-containing pharmaceutical combination for inhalation
PE20040950A1 (es) 2003-02-14 2005-01-01 Theravance Inc DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
TWI324150B (en) * 2003-02-28 2010-05-01 Novartis Ag Process for preparing 5-[(r)-2-(5,6-diethyl-indan-2-ylamino)-1-hydroxy-ethyl]-8-hydroxy-(1h)-quinolin-2-one salt
PE20050211A1 (es) * 2003-04-02 2005-04-27 Novartis Ag Procedimiento para preparar oxi-(1h)-quinolin-2-onas 5-(alfa-haloacetil)-8-sustituidas
GB0307856D0 (en) * 2003-04-04 2003-05-14 Novartis Ag Organic compounds
AU2004226824B2 (en) * 2003-04-04 2008-05-01 Novartis Ag Quinoline-2-one-derivatives for the treatment of airways diseases
AR044519A1 (es) 2003-05-02 2005-09-14 Novartis Ag Derivados de piridin-tiazol amina y de pirimidin-tiazol amina
ATE357258T1 (de) * 2003-07-29 2007-04-15 Boehringer Ingelheim Int Medikamente zur inhalation mit betamimetika und einem anticholinergikum
TW200526547A (en) 2003-09-22 2005-08-16 Theravance Inc Amino-substituted ethylamino β2 adrenergic receptor agonists
TW200531692A (en) 2004-01-12 2005-10-01 Theravance Inc Aryl aniline derivatives as β2 adrenergic receptor agonists
GB0401334D0 (en) 2004-01-21 2004-02-25 Novartis Ag Organic compounds
WO2005092861A1 (en) * 2004-03-11 2005-10-06 Pfizer Limited Quinolinone derivatives pharmaceutical compositions containing them and their use
EP1574501A1 (en) * 2004-03-11 2005-09-14 Pfizer Limited Quinolinone derivatives, pharmaceutical compositions containing them and their use
US8182792B2 (en) 2004-03-23 2012-05-22 Novartis Ag Pharmaceutical compositions
GB0410712D0 (en) 2004-05-13 2004-06-16 Novartis Ag Organic compounds
GB0411056D0 (en) * 2004-05-18 2004-06-23 Novartis Ag Organic compounds
ES2257152B1 (es) * 2004-05-31 2007-07-01 Laboratorios Almirall S.A. Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.
GB0413960D0 (en) * 2004-06-22 2004-07-28 Novartis Ag Organic compounds
EP1786762A2 (en) * 2004-09-10 2007-05-23 Theravance, Inc. Amidine substituted aryl aniline compounds
GT200500281A (es) 2004-10-22 2006-04-24 Novartis Ag Compuestos organicos.
GB0424284D0 (en) 2004-11-02 2004-12-01 Novartis Ag Organic compounds
GB0426164D0 (en) 2004-11-29 2004-12-29 Novartis Ag Organic compounds
GB0507577D0 (en) 2005-04-14 2005-05-18 Novartis Ag Organic compounds
GB0510390D0 (en) 2005-05-20 2005-06-29 Novartis Ag Organic compounds
GB0511065D0 (en) * 2005-05-31 2005-07-06 Novartis Ag Organic compounds
GB0511066D0 (en) * 2005-05-31 2005-07-06 Novartis Ag Organic compounds
TW200738634A (en) 2005-08-02 2007-10-16 Astrazeneca Ab New salt
GB0516313D0 (en) 2005-08-08 2005-09-14 Argenta Discovery Ltd Azole derivatives and their uses
NZ566068A (en) 2005-08-08 2011-03-31 Argenta Discovery Ltd Bicyclo[2.2.1]hept-7-ylamine derivatives and their uses
TW200738658A (en) 2005-08-09 2007-10-16 Astrazeneca Ab Novel compounds
WO2007024183A1 (en) * 2005-08-26 2007-03-01 Astrazeneca Ab A combination of compounds, which can be used in the treatment of respiratory diseases, especially chronic obstructive pulmonary disease (copd) and asthma
NZ567124A (en) 2005-10-21 2011-08-26 Novartis Ag Human antibodies against Interleukin-13 and therapeutic uses to treat asthma
TWI392493B (zh) * 2005-10-26 2013-04-11 Novartis Ag 格隆溴銨(GLYCOPYRROLATE)及β2腎上腺素受體激動劑之組合
GB0525671D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
GB0526244D0 (en) 2005-12-22 2006-02-01 Novartis Ag Organic compounds
JO2660B1 (en) 2006-01-20 2012-06-17 نوفارتيس ايه جي Pi-3 inhibitors and methods of use
GB0601951D0 (en) 2006-01-31 2006-03-15 Novartis Ag Organic compounds
GB0602778D0 (en) 2006-02-10 2006-03-22 Glaxo Group Ltd Novel compound
TW200745067A (en) 2006-03-14 2007-12-16 Astrazeneca Ab Novel compounds
PT2013211E (pt) 2006-04-21 2012-06-21 Novartis Ag Derivados de purina para utilização como agonistas de receptores a2a de adenosina
CN101479245B (zh) 2006-06-30 2013-05-22 诺瓦提斯公司 喹啉酮衍生物和其药物组合物
EP1878722A1 (en) * 2006-07-13 2008-01-16 Novartis AG Quinolinone derivatives and their pharmaceutical compositions
EP1914227A1 (en) * 2006-08-31 2008-04-23 Novartis AG Polymorphic crystal form of a indan-2-ylamino-hydroxyethyl-quinolinone maleate derivative as beta-adrenoceptor agonist
AU2007302263A1 (en) 2006-09-29 2008-04-03 Novartis Ag Pyrazolopyrimidines as P13K lipid kinase inhibitors
JP2010508315A (ja) 2006-10-30 2010-03-18 ノバルティス アーゲー 抗炎症剤としてのヘテロ環式化合物
TW200833670A (en) 2006-12-20 2008-08-16 Astrazeneca Ab Novel compounds 569
RS51644B (en) 2007-01-10 2011-10-31 Irm Llc. UNITS AND PREPARATIONS AS CHANNEL INHIBITORS ACTIVATING PROSTHESES
GB0702458D0 (en) 2007-02-08 2007-03-21 Astrazeneca Ab Salts 668
EP2117541A1 (en) 2007-02-09 2009-11-18 Irm Llc Compounds and compositions as channel activating protease inhibitors
PL2155721T3 (pl) 2007-05-07 2011-07-29 Novartis Ag Związki organiczne
JP5455922B2 (ja) 2007-12-10 2014-03-26 ノバルティス アーゲー 有機化合物
PL2231642T3 (pl) 2008-01-11 2014-04-30 Novartis Ag Pirymidyny jako inhibitory kinazy
US8268834B2 (en) 2008-03-19 2012-09-18 Novartis Ag Pyrazine derivatives that inhibit phosphatidylinositol 3-kinase enzyme
JP2011522860A (ja) 2008-06-10 2011-08-04 ノバルティス アーゲー 上皮性ナトリウムチャネルブロッカーとしてのピラジン誘導体
WO2009154557A1 (en) 2008-06-18 2009-12-23 Astrazeneca Ab Benzoxazinone derivatives acting as beta2-adrenoreceptor agonist for the treatment of respiratory disorders
US8236786B2 (en) 2008-08-07 2012-08-07 Pulmagen Therapeutics (Inflammation) Limited Respiratory disease treatment
MX2011007036A (es) 2008-12-30 2011-07-20 Pulmagen Therapeutics Inflammation Ltd Compuestos de sulfonamida para el tratamiento de trastornos respiratorios.
TW201031406A (en) 2009-01-29 2010-09-01 Novartis Ag Substituted benzimidazoles for the treatment of astrocytomas
UY32442A (es) * 2009-02-13 2010-09-30 Sanofi Aventis Nuevos indanos sustituidos, procesos para su preparacion y uso de los mismos como un medicamento
WO2010150014A1 (en) 2009-06-24 2010-12-29 Pulmagen Therapeutics (Inflammation) Limited 5r- 5 -deuterated glitazones for respiratory disease treatment
US8389526B2 (en) 2009-08-07 2013-03-05 Novartis Ag 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
BR112012003262A8 (pt) 2009-08-12 2016-05-17 Novartis Ag compostos de hidrazona heterocíclica e seus usos para tratar câncer e inflamação
PE20121148A1 (es) 2009-08-17 2012-09-07 Intellikine Llc Compuestos heterociclicos y usos de los mismos
EA201200318A1 (ru) 2009-08-20 2012-09-28 Новартис Аг Гетероциклические оксимы
CN102665715A (zh) 2009-10-22 2012-09-12 沃泰克斯药物股份有限公司 治疗囊性纤维化和其他慢性疾病的组合物
GB0918922D0 (en) 2009-10-28 2009-12-16 Vantia Ltd Aminopyridine derivatives
GB0918923D0 (en) 2009-10-28 2009-12-16 Vantia Ltd Aminothiazole derivatives
GB0918924D0 (en) 2009-10-28 2009-12-16 Vantia Ltd Azaindole derivatives
US8877930B2 (en) 2009-11-04 2014-11-04 Massachusetts Institute Of Technology Continuous flow synthesis of amino alcohols using microreactors
WO2011098746A1 (en) 2010-02-09 2011-08-18 Pulmagen Therapeutics (Inflammation) Limited Crystalline acid addition salts of ( 5r) -enanti0mer of pioglitazone
GB201002243D0 (en) 2010-02-10 2010-03-31 Argenta Therapeutics Ltd Respiratory disease treatment
GB201002224D0 (en) 2010-02-10 2010-03-31 Argenta Therapeutics Ltd Respiratory disease treatment
RU2012136148A (ru) * 2010-02-18 2014-03-27 Астразенека Аб Новая кристаллическая форма производного циклопропилбензамида
WO2011109276A1 (en) 2010-03-01 2011-09-09 Massachussets Institute Of Technology Epoxidation catalysts
US8247436B2 (en) 2010-03-19 2012-08-21 Novartis Ag Pyridine and pyrazine derivative for the treatment of CF
WO2012007539A1 (en) 2010-07-14 2012-01-19 Novartis Ag Ip receptor agonist heterocyclic compounds
US8637516B2 (en) 2010-09-09 2014-01-28 Irm Llc Compounds and compositions as TRK inhibitors
WO2012034095A1 (en) 2010-09-09 2012-03-15 Irm Llc Compounds and compositions as trk inhibitors
US8372845B2 (en) 2010-09-17 2013-02-12 Novartis Ag Pyrazine derivatives as enac blockers
KR20180028563A (ko) 2010-10-12 2018-03-16 시플라 리미티드 약학 조성물
JOP20120023B1 (ar) 2011-02-04 2022-03-14 Novartis Ag صياغات مساحيق جافة من جسيمات تحتوي على واحد أو اثنين من المواد الفعالة لعلاج امراض ممرات الهواء الانسدادية او الالتهابية
US20130324526A1 (en) 2011-02-10 2013-12-05 Novartis Ag [1,2,4] triazolo [4,3-b] pyridazine compounds as inhibitors of the c-met tyrosine kinase
EP2678016B1 (en) 2011-02-23 2016-08-10 Intellikine, LLC Heterocyclic compounds and uses thereof
GEP20156285B (en) 2011-02-25 2015-05-11 Aierem Elelsi Compounds and compositions as trk inhibitors
UY34305A (es) 2011-09-01 2013-04-30 Novartis Ag Derivados de heterociclos bicíclicos para el tratamiento de la hipertensión arterial pulmonar
JP5957526B2 (ja) 2011-09-15 2016-07-27 ノバルティス アーゲー チロシンキナーゼとしての６−置換３−（キノリン−６−イルチオ）−［１，２，４］トリアゾロ［４，３−ａ］ピラジン
WO2013038378A1 (en) 2011-09-16 2013-03-21 Novartis Ag Pyridine amide derivatives
ES2882807T3 (es) 2011-09-16 2021-12-02 Novartis Ag Heterociclil carboxamidas N-sustituidas
WO2013038381A1 (en) 2011-09-16 2013-03-21 Novartis Ag Pyridine/pyrazine amide derivatives
WO2013038373A1 (en) 2011-09-16 2013-03-21 Novartis Ag Pyridine amide derivatives
CN103946221B (zh) 2011-09-16 2016-08-03 诺华股份有限公司 用于治疗囊性纤维化的杂环化合物
CN104363914A (zh) 2011-11-23 2015-02-18 因特利凯有限责任公司 使用mTOR抑制剂的增强的治疗方案
EP2802583A1 (en) 2012-01-13 2014-11-19 Novartis AG Fused piperidines as ip receptor agonists for the treatment of pulmonary arterial hypertension (pah) and related disorders
EP2802581A1 (en) 2012-01-13 2014-11-19 Novartis AG 7,8- dihydropyrido [3, 4 - b]pyrazines as ip receptor agonists for the treatment of pulmonary arterial hypertension (pah) and related disorders
CN104053659B (zh) 2012-01-13 2016-11-09 诺华股份有限公司 用于治疗肺动脉高压(pah)及相关病症的作为ip 受体激动剂的稠合的吡咯类
EP2802584B1 (en) 2012-01-13 2015-11-18 Novartis AG Salts of an ip receptor agonist
US20140357641A1 (en) 2012-01-13 2014-12-04 Novartis Ag IP receptor agonist heterocyclic compounds
US9115129B2 (en) 2012-01-13 2015-08-25 Novartis Ag Substituted pyrido[2,3-B]pyrazines as IP receptor agonists
WO2013132514A2 (en) * 2012-03-09 2013-09-12 Rao Davuluri Ramamohan A novel process for the preparation of (r)-5-[2-[(5, 6-diethyl-2, 3-dihydro-1h-inden-2-yl) amino]-1-hydroxyethyl]-8-hydroxy quinolin-2(1h)-one
US8809340B2 (en) 2012-03-19 2014-08-19 Novartis Ag Crystalline form
RU2660354C2 (ru) 2012-04-03 2018-07-05 Новартис Аг Комбинированные продукты, содержащие ингибиторы тирозинкиназ, и их применение
WO2014008639A1 (zh) * 2012-07-11 2014-01-16 上海威智医药科技有限公司 制备茚达特罗的方法
WO2014008640A1 (zh) * 2012-07-11 2014-01-16 上海威智医药科技有限公司 茚达特罗中间体及茚达特罗的合成方法
CN103539677B (zh) * 2012-07-16 2015-04-22 武汉万知生物医药有限公司 一种5,6-二乙基-2,3-二氢-1h-茚-2-胺盐酸盐的制备方法
WO2014044288A1 (en) 2012-09-21 2014-03-27 Crystal Pharma Sa Methods for the preparation of indacaterol and pharmaceutically acceptable salts thereof
EP3848354B1 (en) 2012-09-21 2022-07-27 Crystal Pharma, S.A.U. Process for the preparation of indacaterol and intermediates thereof
ES2715682T3 (es) 2012-12-19 2019-06-05 Novartis Ag Inhibidores de la autotaxina
US9784726B2 (en) 2013-01-08 2017-10-10 Atrogi Ab Screening method, a kit, a method of treatment and a compound for use in a method of treatment
EP2956455B1 (en) 2013-02-13 2017-05-17 Novartis AG Ip receptor agonist heterocyclic compounds
US9073921B2 (en) 2013-03-01 2015-07-07 Novartis Ag Salt forms of bicyclic heterocyclic derivatives
US9452139B2 (en) 2013-03-14 2016-09-27 Novartis Ag Respirable agglomerates of porous carrier particles and micronized drug
RU2698331C2 (ru) 2013-03-14 2019-08-26 Новартис Аг Деаморфизация высушенных распылением составов посредством смешивания распылением
CZ306252B6 (cs) 2013-03-15 2016-10-26 Zentiva, K.S. Způsob přípravy 5-[(R)-2-(5,6-diethylindan-2-ylamino)-1-hydroxyethyl]-8-hydroxy-(1H)-chinolin-2-onu (indacaterolu)
EP2968340A4 (en) 2013-03-15 2016-08-10 Intellikine Llc COMBINING KINASE INHIBITORS AND USES THEREOF
WO2014154841A1 (en) * 2013-03-27 2014-10-02 Laboratorios Lesvi, S.L. Process for the manufacture of (r)-5-[2-(5,6-diethylindan-2-ylamino)-1-hydroxyethyl]-8-hydroxy-(1h)-quinolin-2-one
CU24355B1 (es) 2013-07-18 2018-08-06 Novartis Ag Derivados de 2((( oxadiazol/triazol/tetrazol/isoxazol) metil) fenil)-1-(heterociclil)-ona como inhibidores activos de autotaxina
EP3022201A1 (en) 2013-07-18 2016-05-25 Novartis AG Autotaxin inhibitors
TW201605450A (zh) 2013-12-03 2016-02-16 諾華公司 Ｍｄｍ２抑制劑與ＢＲＡＦ抑制劑之組合及其用途
CN104744360B (zh) * 2013-12-26 2017-02-22 成都伊诺达博医药科技有限公司 一种合成茚达特罗的新方法
PT3092217T (pt) 2014-01-09 2020-09-04 Ramamohan Rao Davuluri Processo inovador para preparação de indacaterol ou dos seus sais farmaceuticamente aceitáveis
CN103830193A (zh) * 2014-03-11 2014-06-04 熊妲妮 茚达特罗片制剂及其制备方法
CN103830195A (zh) * 2014-03-11 2014-06-04 熊妲妮 一种茚达特罗片及其制备方法
JP2017508776A (ja) 2014-03-27 2017-03-30 ノバルティス アーゲー 医薬品有効成分吸入用の噴霧乾燥した水中油中固体分散体
EA032075B1 (ru) 2014-04-24 2019-04-30 Новартис Аг Производные аминопиразина в качестве ингибиторов фосфатидилинозитол-3-киназы
EP3134398A1 (en) 2014-04-24 2017-03-01 Novartis Ag Autotaxin inhibitors
AU2014391610B2 (en) 2014-04-24 2018-01-25 Novartis Ag Pyrazine derivatives as phosphatidylinositol 3-kinase inhibitors
US10112926B2 (en) 2014-04-24 2018-10-30 Novartis Ag Amino pyridine derivatives as phosphatidylinositol 3-kinase inhibitors
WO2016011658A1 (en) 2014-07-25 2016-01-28 Novartis Ag Combination therapy
US10195208B2 (en) 2014-07-31 2019-02-05 Novartis Ag Combination therapy
DE102014217205A1 (de) 2014-08-28 2016-03-03 Henkel Ag & Co. Kgaa Verwendung einer Kombination von Rheolate FX 1100 und Luviskol VA 64 W
DE102014217201A1 (de) 2014-08-28 2016-03-03 Henkel Ag & Co. Kgaa Verwendung einer Kombination von Rheolate FX 1100 und Luviskol K90
ES2758677T3 (es) * 2015-01-20 2020-05-06 Olon Spa Procedimiento para la preparación de derivados de indanamina y nuevos compuestos intermedios de síntesis
CN107111687A (zh) 2015-01-20 2017-08-29 诺华股份有限公司 使用连接的物理设备以及其间的数据传输进行应用解锁
WO2016161956A1 (zh) * 2015-04-09 2016-10-13 正大天晴药业集团股份有限公司 茚达特罗或其盐的制备方法
EP3111978B1 (en) 2015-07-03 2021-09-01 Novartis AG Inhaler adapted to read information stored in a data storage means of a container
ITUB20153978A1 (it) * 2015-09-28 2017-03-28 Laboratorio Chimico Int S P A Procedimento per la preparazione di derivati di indanammina e di nuovi intermedi di sintesi.
CN105884626B (zh) * 2016-05-04 2017-10-20 龙曦宁（上海）医药科技有限公司 一种2‑氨基茚满衍生物的合成方法及其产品
CN108101841B (zh) * 2016-11-24 2021-04-06 江苏恒瑞医药股份有限公司 一种制备茚达特罗或其盐的方法
GB201714745D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714734D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714740D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714736D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
EP3735406B1 (en) 2018-01-02 2022-05-11 Deva Holding Anonim Sirketi A process for preparation of 5-(2-(substituted-amino)-1-hydroxyethyl)-8-(substituted-oxy) quinolin-2(1h)-one
WO2019182718A1 (en) 2018-03-19 2019-09-26 Dow Silicones Corporation Hot melt adhesive composition containing a polyolefin - polydiorganosiloxane copolymer and methods for the preparation and use thereof
JP7378411B2 (ja) 2018-03-19 2023-11-13 ダウ シリコーンズ コーポレーション ポリオレフィン－ポリジオルガノシロキサンブロックコポリマーおよびその合成のための加水分解反応方法
KR102731725B1 (ko) 2018-03-19 2024-11-20 다우 글로벌 테크놀로지스 엘엘씨 폴리올레핀 - 폴리디오르가노실록산 공중합체를 함유하는 폴리오르가노실록산 핫멜트 접착제 조성물 및 이의 제조 방법 및 사용
EP3768766B1 (en) 2018-03-19 2025-09-24 Dow Silicones Corporation Polyolefin-polydiorganosiioxane block copolymer and method for the synthesis thereof
EP3824017B1 (en) 2018-07-17 2022-09-14 Dow Silicones Corporation Polysiloxane resin - polyolefin copolymer and methods for the preparation and use thereof
WO2020047225A1 (en) 2018-08-30 2020-03-05 Theravance Biopharma R&D Ip, Llc Methods for treating chronic obstructive pulmonary disease
CA3114672A1 (en) 2018-10-05 2020-04-23 Vertex Pharmaceuticals Incorporated Modulators of alpha-1 antitrypsin
CN109369417B (zh) * 2018-10-19 2021-07-06 诚达药业股份有限公司 一种2-氨基茚满衍生物的制备方法
WO2020105012A1 (en) 2018-11-22 2020-05-28 Glenmark Specialty S.A. Sterile compositions of indacaterol suitable for nebulization
WO2020141472A1 (en) 2019-01-03 2020-07-09 Glenmark Specialty S.A. Nebulization composition comprising tiotropium and indacaterol
GB201903832D0 (en) 2019-03-20 2019-05-01 Atrogi Ab New compounds and methods
CN109896966B (zh) * 2019-04-04 2021-10-22 上海工程技术大学 一种n,n-二丁基间氨基苯酚的制备方法
CN109896967B (zh) * 2019-04-04 2021-10-22 上海工程技术大学 一种间二乙氨基苯酚的制备方法
UY38696A (es) 2019-05-14 2020-11-30 Vertex Pharma Moduladores de alfa-1 antitripsina
CN110229078A (zh) * 2019-05-22 2019-09-13 博诺康源(北京)药业科技有限公司 一种茚达特罗起始原料开环杂质的制备
AU2020290094B2 (en) 2019-06-10 2024-01-18 Novartis Ag Pyridine and pyrazine derivative for the treatment of CF, COPD, and bronchiectasis
UY38860A (es) 2019-08-28 2021-02-26 Novartis Ag Derivados de 1,3–fenil heteroarilo sustituidos, composiciones para su uso en el tratamiento de enfermedades y formas cristalinas
TW202140550A (zh) 2020-01-29 2021-11-01 瑞士商諾華公司 使用抗ｔｓｌｐ抗體治療炎性或阻塞性氣道疾病之方法
WO2021203028A1 (en) * 2020-04-03 2021-10-07 Vertex Pharmaceuticals Incorporated 7- or 8-hydroxy-isoquinoline and 7- or 8-hydroxy-quinoline derivatives as alpha-1 -antitrypsin modulators for treating alpha-1 -antitrypsin deficiency (aatd)
JP7545570B2 (ja) 2020-08-14 2024-09-04 ノバルティス アーゲー ヘテロアリール置換スピロピペリジニル誘導体及びその薬学的使用
US11844793B2 (en) 2020-09-29 2023-12-19 Aerorx Therapeutics Llc Liquid formulations of indacaterol
CN115677577B (zh) * 2021-11-03 2024-11-15 中国药科大学 靶向srsf6蛋白的小分子化合物及其制备方法和用途
GB202205895D0 (en) 2022-04-22 2022-06-08 Atrogi Ab New medical uses
CN115521254B (zh) * 2022-09-27 2024-05-31 中国药科大学 一种茚达特罗衍生物及其制备方法和应用
WO2024153813A1 (en) 2023-01-20 2024-07-25 Atrogi Ab Beta 2-adrenergic receptor agonists for treatment or prevention of muscle wasting
GB202302225D0 (en) 2023-02-16 2023-04-05 Atrogi Ab New medical uses
GB202303229D0 (en) 2023-03-06 2023-04-19 Atrogi Ab New medical uses
WO2024206662A1 (en) * 2023-03-30 2024-10-03 Aerorx Therapeutics Llc Liquid formulations of indacaterol and glycopyrronium
GB202403169D0 (en) 2024-03-05 2024-04-17 Atrogi Ab New medical uses

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2354959C3 (de) * 1973-11-02 1980-02-07 Dr. Karl Thomae Gmbh, 7950 Biberach Neues Verfahren zur Herstellung von 4-Amino-3,5 dihalogen phenyl-athanolaminen
GB8707123D0 (en) 1987-03-25 1987-04-29 Pfizer Ltd Antiarrhythmic agents
AU632809B2 (en) 1989-05-25 1993-01-14 Takeda Chemical Industries Ltd. Benzocycloalkane benzopyran and benzothiopyran urea derivatives and production thereof
ZA903906B (en) * 1989-05-25 1992-02-26 Takeda Chemical Industries Ltd Benzocycloalkane derivatives and production thereof
CA2107682A1 (en) * 1991-04-10 1992-10-11 Javier Navarro Interleukin-8 receptors and related molecules and methods
GB9107827D0 (en) 1991-04-12 1991-05-29 Fujisawa Pharmaceutical Co New ethanolamine derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same
JPH0518007A (ja) 1991-07-05 1993-01-26 Konoike Constr Ltd 鉄骨梁との接合部を内蔵したｐｃ柱
IL104567A (en) * 1992-02-03 1997-03-18 Fujisawa Pharmaceutical Co Ethanolamine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
WO1993018007A1 (en) * 1992-03-13 1993-09-16 Tokyo Tanabe Company Limited Novel carbostyril derivative
ATE163930T1 (de) 1993-01-29 1998-03-15 American Cyanamid Co Aminocycloalkanobenzodioxole als beta-3 selektive adrenergische wirkstoffe
DE69422044T2 (de) 1993-08-06 2000-05-31 Pharmacia & Upjohn Co., Kalamazoo 2-aminoindane als selektive dopamin-d3-liganden
FR2711407B1 (fr) * 1993-10-19 1996-01-26 Allevard Sa Perfectionnements aux barres de torsion métalliques.
US5578638A (en) 1993-11-05 1996-11-26 American Cyanamid Company Treatment of glaucoma and ocular hypertension with β3 -adrenergic agonists
GB9405019D0 (en) 1994-03-15 1994-04-27 Smithkline Beecham Plc Novel compounds
RU2161601C2 (ru) 1995-02-01 2001-01-10 Фармация Энд Апджон Компани 2-аминоинданы в качестве селективных лигандов допамина д3
ZA967892B (en) 1995-09-21 1998-03-18 Lilly Co Eli Selective β3 adrenergic agonists.
SG72727A1 (en) * 1996-02-19 2000-05-23 Kissei Pharmaceutical 3,4-Disubstituted phenylethanolaminotetralincarboxamide derivatives
JP3708624B2 (ja) 1996-03-27 2005-10-19 キッセイ薬品工業株式会社 ３，４−ジ置換フェニルエタノールアミノテトラリンカルボン酸誘導体
JP3690071B2 (ja) 1997-06-24 2005-08-31 井関農機株式会社 ロータリ耕耘具の防護装置
AU8562098A (en) 1997-08-19 1999-03-08 Kissei Pharmaceutical Co. Ltd. Phenylethanolaminotetralin derivatives and bronchodilators
US6495546B1 (en) * 1998-04-06 2002-12-17 Fujisawa Pharmaceutical Co., Ltd. Propanolamine derivatives
US6916828B2 (en) 2000-06-27 2005-07-12 Laboratorios S.A.L.V.A.T., S.A. Carbamates derivatived from arylakylamines

Also Published As

Publication number Publication date
CZ302403B6 (cs) 2011-05-04
IL146578A0 (en) 2002-07-25
US7820694B2 (en) 2010-10-26
PT2332915E (pt) 2013-04-11
HUP0201658A2 (en) 2002-08-28
US20140343091A1 (en) 2014-11-20
CN1156451C (zh) 2004-07-07
DE60042781D1 (de) 2009-10-01
DE122010000009I2 (de) 2012-08-09
HK1045837A1 (en) 2002-12-13
NO2010014I1 (no) 2010-07-26
KR100718615B1 (ko) 2007-05-16
FR10C0006I1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2010-03-26
BR0011324B1 (pt) 2014-11-25
EP1183240B1 (en) 2009-08-19
DK1183240T3 (da) 2009-11-23
US7622483B2 (en) 2009-11-24
HUP0201658A3 (en) 2005-01-28
BRPI0011324B8 (pt) 2021-05-25
CY1114120T1 (el) 2016-07-27
EP2332915B1 (en) 2013-02-27
NO322944B1 (no) 2006-12-18
US8796307B2 (en) 2014-08-05
CZ20014301A3 (cs) 2002-03-13
US8283362B2 (en) 2012-10-09
US6878721B1 (en) 2005-04-12
CY1109604T1 (el) 2012-01-25
RU2244709C2 (ru) 2005-01-20
NZ515669A (en) 2004-01-30
TR200103497T2 (tr) 2002-05-21
PE20010219A1 (es) 2001-03-21
TWI253447B (en) 2006-04-21
CA2375810C (en) 2010-09-07
ES2331457T3 (es) 2010-01-05
AR035548A1 (es) 2004-06-16
US20140066478A1 (en) 2014-03-06
US8436017B2 (en) 2013-05-07
HK1045837B (en) 2010-03-26
ATE440083T1 (de) 2009-09-15
JP3785365B2 (ja) 2006-06-14
LU91651I9 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2019-01-03
DK2332915T3 (da) 2013-05-27
US20120302531A1 (en) 2012-11-29
MY126951A (en) 2006-11-30
HU227034B1 (en) 2010-05-28
ES2402535T3 (es) 2013-05-06
US20130231367A1 (en) 2013-09-05
PT1183240E (pt) 2009-11-03
SK17432001A3 (sk) 2002-06-04
ZA200109931B (en) 2002-06-05
US9040559B2 (en) 2015-05-26
LU91651I2 (fr) 2010-04-19
NL300437I1 (nl) 2010-04-01
WO2000075114A1 (en) 2000-12-14
DE122010000009I1 (de) 2010-07-01
CA2375810A1 (en) 2000-12-14
JP2003501417A (ja) 2003-01-14
BR0011324A (pt) 2002-03-05
KR20020012590A (ko) 2002-02-16
PL198847B1 (pl) 2008-07-31
SI1183240T1 (sl) 2010-01-29
AU765919B2 (en) 2003-10-02
CO5170518A1 (es) 2002-06-27
CY2010003I1 (el) 2012-01-25
CN1353692A (zh) 2002-06-12
SK287260B6 (sk) 2010-04-07
US8658673B2 (en) 2014-02-25
MXPA01012474A (es) 2002-06-04
HK1154584A1 (en) 2012-04-27
IL146578A (en) 2007-05-15
NO20015912D0 (no) 2001-12-03
AU5074500A (en) 2000-12-28
US20100029705A1 (en) 2010-02-04
EP2332915A1 (en) 2011-06-15
FR10C0006I2 (fr) 2011-04-01
US20050153957A1 (en) 2005-07-14
CY2010003I2 (el) 2012-01-25
US20110034509A1 (en) 2011-02-10
US8067437B2 (en) 2011-11-29
US20120077838A1 (en) 2012-03-29
NO2010014I2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2011-10-17
BE2010C011I2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2019-05-21
PL352100A1 (en) 2003-07-28
EP1183240A1 (en) 2002-03-06
NO20015912L (no) 2002-01-21

Similar Documents

Publication Publication Date Title
GB9913083D0 (en) Organic compounds
GB9903759D0 (en) Organic compounds
GB9903547D0 (en) Organic compounds
GB9907097D0 (en) Organic compounds
GB9908533D0 (en) Organic compounds
GB9902938D0 (en) Organic compounds
GB9903548D0 (en) Organic compounds
GB9907908D0 (en) Organic compounds
GB9910119D0 (en) Organic compounds
GB9910965D0 (en) Organic compounds
GB9904544D0 (en) Organic compounds
GB9906060D0 (en) Organic compounds
GB9903546D0 (en) Organic compounds
GB9903667D0 (en) Organic compounds
GB9903669D0 (en) Organic compounds
GB9903754D0 (en) Organic compounds
GB9903755D0 (en) Organic compounds
GB9903757D0 (en) Organic compounds
GB9903761D0 (en) Organic compounds
GB9903876D0 (en) Organic compounds
GB9903878D0 (en) Organic compounds
GB9903948D0 (en) Organic compounds
GB9903949D0 (en) Organic compounds
GB9904423D0 (en) Organic compounds
GB9905946D0 (en) Organic compounds

Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)