ITUB20153978A1 - Procedimento per la preparazione di derivati di indanammina e di nuovi intermedi di sintesi. - Google Patents

Procedimento per la preparazione di derivati di indanammina e di nuovi intermedi di sintesi.

Info

Publication number
ITUB20153978A1
ITUB20153978A1 ITUB2015A003978A ITUB20153978A ITUB20153978A1 IT UB20153978 A1 ITUB20153978 A1 IT UB20153978A1 IT UB2015A003978 A ITUB2015A003978 A IT UB2015A003978A IT UB20153978 A ITUB20153978 A IT UB20153978A IT UB20153978 A1 ITUB20153978 A1 IT UB20153978A1
Authority
IT
Italy
Prior art keywords
preparation
synthetic intermediates
new synthetic
indanamine
derivatives
Prior art date
Application number
ITUB2015A003978A
Other languages
English (en)
Original Assignee
Laboratorio Chimico Int S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorio Chimico Int S P A filed Critical Laboratorio Chimico Int S P A
Priority to ITUB2015A003978A priority Critical patent/ITUB20153978A1/it
Priority to EP16788192.9A priority patent/EP3356322B1/en
Priority to ES16788192T priority patent/ES2784367T3/es
Priority to JP2018515781A priority patent/JP6911015B2/ja
Priority to PCT/IB2016/001383 priority patent/WO2017055905A1/en
Priority to US15/759,859 priority patent/US10538479B2/en
Priority to CN201680056107.5A priority patent/CN108137479B/zh
Publication of ITUB20153978A1 publication Critical patent/ITUB20153978A1/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/39Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
    • C07C211/41Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems
    • C07C211/42Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems with six-membered aromatic rings being part of the condensed ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/24Oxygen atoms attached in position 8
    • C07D215/26Alcohols; Ethers thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
ITUB2015A003978A 2015-09-28 2015-09-28 Procedimento per la preparazione di derivati di indanammina e di nuovi intermedi di sintesi. ITUB20153978A1 (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
ITUB2015A003978A ITUB20153978A1 (it) 2015-09-28 2015-09-28 Procedimento per la preparazione di derivati di indanammina e di nuovi intermedi di sintesi.
EP16788192.9A EP3356322B1 (en) 2015-09-28 2016-09-28 Process for the preparation of indanamine derivatives and new synthesis intermediates
ES16788192T ES2784367T3 (es) 2015-09-28 2016-09-28 Procedimiento para la preparación de derivados de indanamina y nuevos compuestos intermedios de síntesis
JP2018515781A JP6911015B2 (ja) 2015-09-28 2016-09-28 インダンアミン誘導体の製法及び新規の合成中間体
PCT/IB2016/001383 WO2017055905A1 (en) 2015-09-28 2016-09-28 Process for the preparation of indanamine derivatives and new synthesis intermediates
US15/759,859 US10538479B2 (en) 2015-09-28 2016-09-28 Process for the preparation of indanamine derivatives and new synthesis intermediates
CN201680056107.5A CN108137479B (zh) 2015-09-28 2016-09-28 用于制备茚满胺衍生物的方法和合成中间体

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITUB2015A003978A ITUB20153978A1 (it) 2015-09-28 2015-09-28 Procedimento per la preparazione di derivati di indanammina e di nuovi intermedi di sintesi.

Publications (1)

Publication Number Publication Date
ITUB20153978A1 true ITUB20153978A1 (it) 2017-03-28

Family

ID=55085753

Family Applications (1)

Application Number Title Priority Date Filing Date
ITUB2015A003978A ITUB20153978A1 (it) 2015-09-28 2015-09-28 Procedimento per la preparazione di derivati di indanammina e di nuovi intermedi di sintesi.

Country Status (7)

Country Link
US (1) US10538479B2 (it)
EP (1) EP3356322B1 (it)
JP (1) JP6911015B2 (it)
CN (1) CN108137479B (it)
ES (1) ES2784367T3 (it)
IT (1) ITUB20153978A1 (it)
WO (1) WO2017055905A1 (it)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9913083D0 (en) * 1999-06-04 1999-08-04 Novartis Ag Organic compounds
GB0029562D0 (en) * 2000-12-04 2001-01-17 Novartis Ag Organic compounds
TWI243164B (en) * 2001-02-13 2005-11-11 Aventis Pharma Gmbh Acylated indanyl amines and their use as pharmaceuticals
US6933410B2 (en) 2002-03-08 2005-08-23 Novartis Ag Process for preparing 5,6-diethyl-2,3-dihydro-1H-inden-2-amine
EP1648867B1 (en) * 2003-07-17 2013-09-04 Plexxikon Inc. Ppar active compounds
GB0426164D0 (en) * 2004-11-29 2004-12-29 Novartis Ag Organic compounds
WO2008061006A1 (en) * 2006-11-10 2008-05-22 Wyeth Substituted indan-2-yl, tetrahydronaphthalen-2-yl, or dihydr0-2h-chr0men-3-yl arylsulfonamides and methods of their use
US20100210682A1 (en) * 2009-02-19 2010-08-19 Abbott Laboratories Repeated Dosing of TRPV1 Antagonists
WO2014089324A1 (en) * 2012-12-07 2014-06-12 Calitor Sciences, Llc Substituted cyclic compounds and methods of use

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
FRANCOIS BAUR ET AL: "The Identification of Indacaterol as an Ultralong-Acting Inhaled [beta] 2 -Adrenoceptor Agonist", JOURNAL OF MEDICINAL CHEMISTRY, vol. 53, no. 9, 13 May 2010 (2010-05-13), pages 3675 - 3684, XP055121338, ISSN: 0022-2623, DOI: 10.1021/jm100068m *
GOKSU S ET AL: "Concise syntheses of 2-aminoindans via indan-2-ol", TETRAHEDRON, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 61, no. 28, 11 July 2005 (2005-07-11), pages 6801 - 6807, XP027861216, ISSN: 0040-4020, [retrieved on 20050711] *

Also Published As

Publication number Publication date
JP6911015B2 (ja) 2021-07-28
EP3356322B1 (en) 2020-01-15
US10538479B2 (en) 2020-01-21
EP3356322A1 (en) 2018-08-08
CN108137479B (zh) 2021-06-04
US20180258028A1 (en) 2018-09-13
CN108137479A (zh) 2018-06-08
JP2018529700A (ja) 2018-10-11
WO2017055905A1 (en) 2017-04-06
ES2784367T3 (es) 2020-09-24

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