ITUB20160480A1 - Procedimento per la preparazione del Metaraminolo. - Google Patents

Procedimento per la preparazione del Metaraminolo.

Info

Publication number
ITUB20160480A1
ITUB20160480A1 ITUB2016A000480A ITUB20160480A ITUB20160480A1 IT UB20160480 A1 ITUB20160480 A1 IT UB20160480A1 IT UB2016A000480 A ITUB2016A000480 A IT UB2016A000480A IT UB20160480 A ITUB20160480 A IT UB20160480A IT UB20160480 A1 ITUB20160480 A1 IT UB20160480A1
Authority
IT
Italy
Prior art keywords
metaraminol
preparation
Prior art date
Application number
ITUB2016A000480A
Other languages
English (en)
Inventor
Davide Brenna
Andrea Marchesi
Voichita MIHALI
Original Assignee
Laboratori Alchemia S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratori Alchemia S R L filed Critical Laboratori Alchemia S R L
Priority to ITUB2016A000480A priority Critical patent/ITUB20160480A1/it
Priority to AU2017200463A priority patent/AU2017200463B2/en
Priority to EP17152814.4A priority patent/EP3199516B1/en
Priority to PL17152814T priority patent/PL3199516T3/pl
Priority to ES17152814T priority patent/ES2750842T3/es
Priority to US15/414,993 priority patent/US10087136B2/en
Publication of ITUB20160480A1 publication Critical patent/ITUB20160480A1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ITUB2016A000480A 2016-01-26 2016-01-26 Procedimento per la preparazione del Metaraminolo. ITUB20160480A1 (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
ITUB2016A000480A ITUB20160480A1 (it) 2016-01-26 2016-01-26 Procedimento per la preparazione del Metaraminolo.
AU2017200463A AU2017200463B2 (en) 2016-01-26 2017-01-23 The process for the preparation of metaraminol
EP17152814.4A EP3199516B1 (en) 2016-01-26 2017-01-24 Process for the preparation of metaraminol
PL17152814T PL3199516T3 (pl) 2016-01-26 2017-01-24 Sposób wytwarzania Metaraminolu
ES17152814T ES2750842T3 (es) 2016-01-26 2017-01-24 Procedimiento para la preparación de metaraminol
US15/414,993 US10087136B2 (en) 2016-01-26 2017-01-25 Process for the preparation of Metaraminol

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITUB2016A000480A ITUB20160480A1 (it) 2016-01-26 2016-01-26 Procedimento per la preparazione del Metaraminolo.

Publications (1)

Publication Number Publication Date
ITUB20160480A1 true ITUB20160480A1 (it) 2017-07-26

Family

ID=55861024

Family Applications (1)

Application Number Title Priority Date Filing Date
ITUB2016A000480A ITUB20160480A1 (it) 2016-01-26 2016-01-26 Procedimento per la preparazione del Metaraminolo.

Country Status (6)

Country Link
US (1) US10087136B2 (it)
EP (1) EP3199516B1 (it)
AU (1) AU2017200463B2 (it)
ES (1) ES2750842T3 (it)
IT (1) ITUB20160480A1 (it)
PL (1) PL3199516T3 (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110437083B (zh) * 2019-08-30 2022-03-22 常州市阳光药业有限公司 重酒石酸间羟胺对映异构体的合成方法
CN112326810A (zh) * 2020-09-28 2021-02-05 南京斯泰尔医药科技有限公司 重酒石酸间羟胺注射液前处理及对映异构体的分离测定
CN116836108A (zh) * 2022-03-25 2023-10-03 北京新领先医药科技发展有限公司 一种用于合成重酒石酸间羟胺的催化剂配体的制备方法
CN115991655B (zh) * 2022-12-27 2024-08-30 新领先(重庆)医药科技有限公司 一种重酒石酸间羟胺及其关键中间体对映异构体的合成方法和产品
CN116332774A (zh) * 2023-03-29 2023-06-27 成都瑞尔医药科技有限公司 一种高手性纯度的重酒石酸间羟胺的制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103739504A (zh) * 2013-12-31 2014-04-23 广州普星药业有限公司 一种重酒石酸间羟胺的合成方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103739504A (zh) * 2013-12-31 2014-04-23 广州普星药业有限公司 一种重酒石酸间羟胺的合成方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GONZALO BLAY ET AL: "New Highly Asymmetric Henry Reaction Catalyzed by CuII and aC1-Symmetric Aminopyridine Ligand, and Its Application to the Synthesis of Miconazole", CHEMISTRY - A EUROPEAN JOURNAL., vol. 14, no. 15, 19 May 2008 (2008-05-19), WEINHEIM, DE, pages 4725 - 4730, XP055302379, ISSN: 0947-6539, DOI: 10.1002/chem.200800069 *

Also Published As

Publication number Publication date
EP3199516B1 (en) 2019-07-24
US10087136B2 (en) 2018-10-02
ES2750842T3 (es) 2020-03-27
PL3199516T3 (pl) 2020-01-31
AU2017200463B2 (en) 2020-12-17
US20170210696A1 (en) 2017-07-27
EP3199516A1 (en) 2017-08-02
AU2017200463A1 (en) 2017-08-10

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