CU24355B1 - Derivados de 2((( oxadiazol/triazol/tetrazol/isoxazol) metil) fenil)-1-(heterociclil)-ona como inhibidores activos de autotaxina - Google Patents

Derivados de 2((( oxadiazol/triazol/tetrazol/isoxazol) metil) fenil)-1-(heterociclil)-ona como inhibidores activos de autotaxina

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Publication number
CU24355B1
CU24355B1 CUP2016000007A CU20160007A CU24355B1 CU 24355 B1 CU24355 B1 CU 24355B1 CU P2016000007 A CUP2016000007 A CU P2016000007A CU 20160007 A CU20160007 A CU 20160007A CU 24355 B1 CU24355 B1 CU 24355B1
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CU
Cuba
Prior art keywords
isoxazol
oxadiazol
tetrazol
triazol
phenyl
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CUP2016000007A
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English (en)
Other versions
CU20160007A7 (es
Inventor
Urs Baettig
David Beattie
Darren Mark Legrand
Andrew Stuart Lister
Jeffrey Mckenna
David William Pearce
David Andrew Sandham
Oliver Ross Steward
Christopher Thomson
Original Assignee
Novartis Ag
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Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CU20160007A7 publication Critical patent/CU20160007A7/es
Publication of CU24355B1 publication Critical patent/CU24355B1/es

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    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

<p>La presente invención se relaciona con nuevos compuestos derivados de 2(((oxadiazol/triazol/tetrazol/isoxazol) metil) fenil)-1-(heterociclil)-ona que tienen la fórmula</p> <p> </p> <p>ESPACIO PARA FORMULA</p> <p> </p> <p>activos como inhibidores de autotaxina, procesos para su preparación, composiciones farmaceúticas y medicamentos que los contienen y a su uso en enfermedades y trastornos mediados por autotaxina tales como cáncer, dolor neuropático y fibrosis.</p>
CUP2016000007A 2013-07-18 2014-07-16 Derivados de 2((( oxadiazol/triazol/tetrazol/isoxazol) metil) fenil)-1-(heterociclil)-ona como inhibidores activos de autotaxina CU24355B1 (es)

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