PL3022202T3 - Inhibitory autotaksyny zawierające heteroaromatyczny rdzeń pierścienia benzylowego - cyklicznego amidu - Google Patents

Inhibitory autotaksyny zawierające heteroaromatyczny rdzeń pierścienia benzylowego - cyklicznego amidu

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Publication number
PL3022202T3
PL3022202T3 PL14766806T PL14766806T PL3022202T3 PL 3022202 T3 PL3022202 T3 PL 3022202T3 PL 14766806 T PL14766806 T PL 14766806T PL 14766806 T PL14766806 T PL 14766806T PL 3022202 T3 PL3022202 T3 PL 3022202T3
Authority
PL
Poland
Prior art keywords
amide
benzyl
heteroaromatic ring
autotaxin inhibitors
cycle core
Prior art date
Application number
PL14766806T
Other languages
English (en)
Inventor
David Beattie
Urs Baettig
Darren Mark Legrand
Andrew Stuart Lister
Jeffrey Mckenna
David William Pearce
David Andrew Sandham
Oliver Ross Steward
Christopher Thomson
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL3022202T3 publication Critical patent/PL3022202T3/pl

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
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    • C07D471/08—Bridged systems

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PL14766806T 2013-07-18 2014-07-16 Inhibitory autotaksyny zawierające heteroaromatyczny rdzeń pierścienia benzylowego - cyklicznego amidu PL3022202T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13177061 2013-07-18
EP14766806.5A EP3022202B1 (en) 2013-07-18 2014-07-16 Autotaxin inhibitors comprising a heteroaromatic ring-benzyl-amide-cycle core
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ES2742077T3 (es) 2020-02-13
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BR112016000779A2 (pt) 2017-07-25
JP6424219B2 (ja) 2018-11-14
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