PL3022202T3 - Inhibitory autotaksyny zawierające heteroaromatyczny rdzeń pierścienia benzylowego - cyklicznego amidu - Google Patents
Inhibitory autotaksyny zawierające heteroaromatyczny rdzeń pierścienia benzylowego - cyklicznego amiduInfo
- Publication number
- PL3022202T3 PL3022202T3 PL14766806T PL14766806T PL3022202T3 PL 3022202 T3 PL3022202 T3 PL 3022202T3 PL 14766806 T PL14766806 T PL 14766806T PL 14766806 T PL14766806 T PL 14766806T PL 3022202 T3 PL3022202 T3 PL 3022202T3
- Authority
- PL
- Poland
- Prior art keywords
- amide
- benzyl
- heteroaromatic ring
- autotaxin inhibitors
- cycle core
- Prior art date
Links
- 102100021977 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 Human genes 0.000 title 1
- 108050004000 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 Proteins 0.000 title 1
- 125000001072 heteroaryl group Chemical group 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A—HUMAN NECESSITIES
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
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- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
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- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
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- A61K31/5375—1,4-Oxazines, e.g. morpholine
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- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
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- Bioinformatics & Cheminformatics (AREA)
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- Diabetes (AREA)
- Obesity (AREA)
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- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Gastroenterology & Hepatology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13177061 | 2013-07-18 | ||
PCT/IB2014/063143 WO2015008230A1 (en) | 2013-07-18 | 2014-07-16 | Autotaxin inhibitors comprising a heteroaromatic ring-benzyl-amide-cycle core |
EP14766806.5A EP3022202B1 (en) | 2013-07-18 | 2014-07-16 | Autotaxin inhibitors comprising a heteroaromatic ring-benzyl-amide-cycle core |
Publications (1)
Publication Number | Publication Date |
---|---|
PL3022202T3 true PL3022202T3 (pl) | 2019-10-31 |
Family
ID=48793121
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL14766806T PL3022202T3 (pl) | 2013-07-18 | 2014-07-16 | Inhibitory autotaksyny zawierające heteroaromatyczny rdzeń pierścienia benzylowego - cyklicznego amidu |
Country Status (25)
Country | Link |
---|---|
US (2) | US9763957B2 (pl) |
EP (1) | EP3022202B1 (pl) |
JP (1) | JP6424219B2 (pl) |
KR (1) | KR20160033726A (pl) |
CN (1) | CN105555783B (pl) |
AP (1) | AP2016009020A0 (pl) |
AU (1) | AU2014291711B2 (pl) |
BR (1) | BR112016000779A8 (pl) |
CA (1) | CA2918284A1 (pl) |
CL (1) | CL2016000117A1 (pl) |
CR (1) | CR20160033A (pl) |
CU (1) | CU24355B1 (pl) |
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PE (1) | PE20160521A1 (pl) |
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BR112016000779A8 (pt) * | 2013-07-18 | 2020-01-07 | Novartis Ag | inibidores de autotaxina que compreendem núcleo do ciclo de benzilamida de anel heteroaromático, seus usos, composição e combinação farmacêuticas |
UA118201C2 (uk) | 2013-11-26 | 2018-12-10 | Ф. Хоффманн-Ля Рош Аг | НОВИЙ ОКТАГІДРОЦИКЛОБУТА[1,2-c;3,4-c']ДИПІРОЛ-2-ІЛ |
EA032357B1 (ru) | 2014-03-26 | 2019-05-31 | Ф. Хоффманн-Ля Рош Аг | Конденсированные [1,4]диазепиновые соединения в качестве ингибиторов продукции аутотаксина (atx) и лизофосфатидиловой кислоты (lpa) |
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