FR17C1031I2 - 3-((3r,4r)-4-methyl-3-[methyl-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-amino]-piperidinyl)-3-oxo-propionitrile comme inhibiteur de la kinase proteinique - Google Patents

3-((3r,4r)-4-methyl-3-[methyl-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-amino]-piperidinyl)-3-oxo-propionitrile comme inhibiteur de la kinase proteinique

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Publication number
FR17C1031I2
FR17C1031I2 FR17C1031C FR17C1031C FR17C1031I2 FR 17C1031 I2 FR17C1031 I2 FR 17C1031I2 FR 17C1031 C FR17C1031 C FR 17C1031C FR 17C1031 C FR17C1031 C FR 17C1031C FR 17C1031 I2 FR17C1031 I2 FR 17C1031I2
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Prior art keywords
methyl
propionitrile
pyrrolo
pyrimidin
piperidinyl
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FR17C1031C
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French (fr)
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Pfizer Products Inc
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Pfizer Products Inc
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Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc
Publication of FR17C1031I1 publication Critical patent/FR17C1031I1/fr
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
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    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

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  • Health & Medical Sciences (AREA)
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  • Pain & Pain Management (AREA)
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  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR17C1031C 2001-05-31 2017-09-04 3-((3r,4r)-4-methyl-3-[methyl-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-amino]-piperidinyl)-3-oxo-propionitrile comme inhibiteur de la kinase proteinique Active FR17C1031I2 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29477501P 2001-05-31 2001-05-31
US34104801P 2001-12-06 2001-12-06
EP02733058A EP1392694A1 (en) 2001-05-31 2002-05-29 Optical resolution of (1-benzyl-4-methylpiperidin-3-yl)-methylamine and the use thereof for the preparation of pyrrolo[2,3]pyrimidine derivatives as protein kinases inhibitors

Publications (2)

Publication Number Publication Date
FR17C1031I1 FR17C1031I1 (fr) 2017-10-13
FR17C1031I2 true FR17C1031I2 (fr) 2018-11-02

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ID=26968730

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FR17C1031C Active FR17C1031I2 (fr) 2001-05-31 2017-09-04 3-((3r,4r)-4-methyl-3-[methyl-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-amino]-piperidinyl)-3-oxo-propionitrile comme inhibiteur de la kinase proteinique

Country Status (52)

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US (2) US7301023B2 (OSRAM)
EP (3) EP1666481B9 (OSRAM)
JP (1) JP4381137B2 (OSRAM)
KR (5) KR100926875B1 (OSRAM)
CN (1) CN1729192A (OSRAM)
AP (1) AP1859A (OSRAM)
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AT (1) ATE519741T1 (OSRAM)
AU (2) AU2002304401C1 (OSRAM)
BE (1) BE2017C032I2 (OSRAM)
BG (1) BG66489B1 (OSRAM)
BR (1) BR0209246A (OSRAM)
CA (1) CA2448281C (OSRAM)
CL (1) CL2008000762A1 (OSRAM)
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EC (1) ECSP034865A (OSRAM)
EE (1) EE05332B1 (OSRAM)
ES (2) ES2393385T3 (OSRAM)
FR (1) FR17C1031I2 (OSRAM)
GE (1) GEP20063784B (OSRAM)
GT (2) GT200200100AA (OSRAM)
HR (1) HRP20030943B1 (OSRAM)
HU (2) HU230876B1 (OSRAM)
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