FI911212A0 - Protein med uratoxidasaktivitet, rekombinantgen som kodar detta, expressionsvektor, mikroorganismer och transformerade celler. - Google Patents

Protein med uratoxidasaktivitet, rekombinantgen som kodar detta, expressionsvektor, mikroorganismer och transformerade celler.

Info

Publication number
FI911212A0
FI911212A0 FI911212A FI911212A FI911212A0 FI 911212 A0 FI911212 A0 FI 911212A0 FI 911212 A FI911212 A FI 911212A FI 911212 A FI911212 A FI 911212A FI 911212 A0 FI911212 A0 FI 911212A0
Authority
FI
Finland
Prior art keywords
protein
uratoxidasaktivitet
transformerade
rekombinantgen
mikroorganismer
Prior art date
Application number
FI911212A
Other languages
English (en)
Other versions
FI105047B (fi
Inventor
Daniel Caput
Pascual Ferrara
Jean-Claude Guillemot
Mourad Kaghad
Richard Legoux
Gerard Loison
Elisabeth Larbre
Johannes Lupker
Pascal Leplatois
Marc Salome
Patrick Laurent
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8909550A external-priority patent/FR2649720A1/fr
Priority claimed from FR8917466A external-priority patent/FR2656530B1/fr
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of FI911212A0 publication Critical patent/FI911212A0/fi
Application granted granted Critical
Publication of FI105047B publication Critical patent/FI105047B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0044—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on other nitrogen compounds as donors (1.7)
    • C12N9/0046—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on other nitrogen compounds as donors (1.7) with oxygen as acceptor (1.7.3)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Glass Compositions (AREA)
  • Saccharide Compounds (AREA)
FI911212A 1989-07-13 1991-03-12 Menetelmä uraattioksidaasiaktiivisuutta, omaavan yhdistelmäproteiinin valmistamiseksi, tätä proteiinia koodittava yhdistelmägeeni, ja tämän sisältävät ekspressiovektorit, mikro-organismit ja transformoidut solut FI105047B (fi)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
FR8909550 1989-07-13
FR8909550A FR2649720A1 (en) 1989-07-13 1989-07-13 Recombinant gene which encodes a protein such as urate oxidase
FR8917466A FR2656530B1 (fr) 1989-12-29 1989-12-29 Gene recombinant pour une expression dans les cellules eucaryotes d'une proteine telle que l'urate oxydase.
FR8917466 1989-12-29
FR9001368A FR2657785A2 (fr) 1989-12-29 1990-02-06 Gene recombinant pour une expression dans les cellules animales d'une proteine telle que l'urate oxydage.
FR9001368 1990-02-06
FR9000532 1990-07-13
PCT/FR1990/000532 WO1991000909A1 (fr) 1989-07-13 1990-07-13 Proteine a activite urate oxydase, gene recombinant codant pour celle-ci, vecteur d'expression, micro-organismes et cellules transformees

Publications (2)

Publication Number Publication Date
FI911212A0 true FI911212A0 (fi) 1991-03-12
FI105047B FI105047B (fi) 2000-05-31

Family

ID=27251947

Family Applications (1)

Application Number Title Priority Date Filing Date
FI911212A FI105047B (fi) 1989-07-13 1991-03-12 Menetelmä uraattioksidaasiaktiivisuutta, omaavan yhdistelmäproteiinin valmistamiseksi, tätä proteiinia koodittava yhdistelmägeeni, ja tämän sisältävät ekspressiovektorit, mikro-organismit ja transformoidut solut

Country Status (24)

Country Link
EP (1) EP0408461B1 (fi)
JP (1) JP2664804B2 (fi)
AT (1) ATE144282T1 (fi)
AU (1) AU636637B2 (fi)
BR (1) BR9006855A (fi)
CA (1) CA2035900C (fi)
DE (2) DE10199042I2 (fi)
DK (1) DK0408461T3 (fi)
ES (1) ES2095243T3 (fi)
FI (1) FI105047B (fi)
GR (1) GR3022085T3 (fi)
HK (1) HK1000099A1 (fi)
HU (1) HU215948B (fi)
IE (1) IE77158B1 (fi)
IL (1) IL95057A (fi)
LU (1) LU90781I2 (fi)
LV (1) LV12000B (fi)
MC (1) MC2145A1 (fi)
NL (1) NL300046I2 (fi)
NO (1) NO2001018I2 (fi)
NZ (1) NZ234453A (fi)
PT (1) PT94680B (fi)
RU (1) RU2105812C1 (fi)
WO (1) WO1991000909A1 (fi)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2971218B2 (ja) * 1991-12-04 1999-11-02 協和醗酵工業株式会社 ウリカーゼ遺伝子およびウリカーゼの製造法
US5691188A (en) 1994-02-14 1997-11-25 American Cyanamid Company Transformed yeast cells expressing heterologous G-protein coupled receptor
AU4424497A (en) * 1996-09-13 1998-04-02 Transkaryotic Therapies, Inc. Therapy for alpha-galactosidase a deficiency
US6083725A (en) 1996-09-13 2000-07-04 Transkaryotic Therapies, Inc. Tranfected human cells expressing human α-galactosidase A protein
DK1588716T3 (da) 1998-08-06 2011-05-23 Mountain View Pharmaceuticals Peg-uratoxidase-konjugater og anvendelse deraf
US6783965B1 (en) * 2000-02-10 2004-08-31 Mountain View Pharmaceuticals, Inc. Aggregate-free urate oxidase for preparation of non-immunogenic polymer conjugates
RU2260051C2 (ru) 2000-08-17 2005-09-10 Адзиномото Ко., Инк. Способ модифицирования трансглутаминаз микроорганизмов
US20040071686A1 (en) 2002-04-25 2004-04-15 Treco Douglas A. Treatment of alpha-galactosidase A deficiency
MX2007012547A (es) 2005-04-11 2008-03-11 Savient Pharmaceuticals Inc Formas variantes de urato oxidasa y uso de las mismas.
US8148123B2 (en) 2005-04-11 2012-04-03 Savient Pharmaceuticals, Inc. Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
TWI418564B (zh) * 2005-04-11 2013-12-11 Savient Pharmaceuticals Inc 利用陽離子界面活性劑之蛋白質純化
US9534013B2 (en) * 2006-04-12 2017-01-03 Horizon Pharma Rheumatology Llc Purification of proteins with cationic surfactant
CZ2007700A3 (cs) 2005-04-11 2008-02-27 Savient Pharmaceuticals, Inc. Variantní forma urátoxidázy a její použití
RU2443426C2 (ru) * 2008-11-07 2012-02-27 Мунтэн Вью Фармасьютикэлз, Инк. Конъюгаты уратоксидазы, фармацевтическая композиция для снижения уровней мочевой кислоты и способ получения вышеупомянутых конъюгатов
CZ2011827A3 (cs) 2009-06-25 2012-09-26 Savient Pharmaceuticals, Inc. Zpusoby a sady pro predpovídání rizika reakce na infuzi a ztráty odezvy zpusobené protilátkami, monitorováním kyseliny mocové v séru behem lécby pegylovanou urikázou
CN109223707B (zh) * 2018-09-13 2020-12-08 中国药科大学 一种尿酸酶外用凝胶制剂、其制备方法及用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1529675A (fr) * 1967-03-29 1968-06-21 Applic Biochimiques Soc Et Urate oxydase à haute activité et sa préparation
SU457723A1 (ru) * 1973-04-09 1977-08-05 Всесоюзный Научно-Исследовательский Витаминный Институт Штамм 313-152 - продуцент уратоксидазы
DE3583194D1 (de) * 1984-07-27 1991-07-18 Unilever Nv Verfahren zur herstellung von einem polypeptid mittels eines transformierten mikroorganismus, ein dazu geeigneter transformierter mikroorganismus, und zur herstellung dieser mikroorganismen geeignete dns sequenzen.
WO1988008450A1 (en) * 1987-05-01 1988-11-03 Birdwell Finlayson Gene therapy for metabolite disorders
JPH0671428B2 (ja) * 1988-08-17 1994-09-14 サッポロビール株式会社 ウリカーゼのｄｎａ配列および製法

Also Published As

Publication number Publication date
WO1991000909A1 (fr) 1991-01-24
NZ234453A (en) 1993-01-27
PT94680A (pt) 1991-04-18
LV12000B (lv) 1998-06-20
EP0408461B1 (fr) 1996-10-16
DE69028884D1 (de) 1996-11-21
BR9006855A (pt) 1991-08-06
HUT56884A (en) 1991-10-28
ATE144282T1 (de) 1996-11-15
GR3022085T3 (en) 1997-03-31
NO2001018I2 (no) 2006-05-01
DK0408461T3 (da) 1997-03-24
NL300046I2 (nl) 2001-12-01
HU906046D0 (en) 1991-07-29
CA2035900A1 (fr) 1991-01-14
IL95057A (en) 1997-07-13
ES2095243T3 (es) 1997-02-16
MC2145A1 (fr) 1992-02-18
RU2105812C1 (ru) 1998-02-27
IE77158B1 (en) 1997-12-03
IL95057A0 (en) 1991-06-10
JP2664804B2 (ja) 1997-10-22
AU636637B2 (en) 1993-05-06
IE902559A1 (en) 1991-02-27
HK1000099A1 (en) 1997-11-21
DE10199042I1 (de) 2002-01-10
CA2035900C (fr) 2000-01-11
JPH04501807A (ja) 1992-04-02
DE10199042I2 (de) 2003-10-23
FI105047B (fi) 2000-05-31
EP0408461A1 (fr) 1991-01-16
DE69028884T2 (de) 1997-05-07
LV12000A (lv) 1998-03-20
PT94680B (pt) 1997-04-30
LU90781I2 (fr) 2001-07-23
NL300046I1 (nl) 2001-09-03
AU6052390A (en) 1991-02-06
HU215948B (hu) 1999-03-29

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Legal Events

Date Code Title Description
SPCF Supplementary protection certificate application filed

Spc suppl protection certif: L20010008

PC Transfer of assignment of patent

Owner name: SANOFI-AVENTIS

SPCG Supplementary protection certificate granted

Spc suppl protection certif: L194

Extension date: 20150712