PT94680A - Processo para a obtencao de uma proteina tendo actividade de urato oxidase gene recombinante que a codifica vector de expressao portador deste gene microorganismos procariotas e celulas eucariotas transformados por este vector de expressao - Google Patents

Processo para a obtencao de uma proteina tendo actividade de urato oxidase gene recombinante que a codifica vector de expressao portador deste gene microorganismos procariotas e celulas eucariotas transformados por este vector de expressao

Info

Publication number
PT94680A
PT94680A PT94680A PT9468090A PT94680A PT 94680 A PT94680 A PT 94680A PT 94680 A PT94680 A PT 94680A PT 9468090 A PT9468090 A PT 9468090A PT 94680 A PT94680 A PT 94680A
Authority
PT
Portugal
Prior art keywords
expression vector
protein
gene
procariotes
eukariot
Prior art date
Application number
PT94680A
Other languages
English (en)
Other versions
PT94680B (pt
Inventor
Daniel Caput
Pascual Ferrara
Jean-Claude Guillemot
Mourad Kaghad
Richard Legoux
Gerard Loison
Elisabeth Larbre
Johannes Lupker
Pascal Leplatois
Marc Salome
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8909550A external-priority patent/FR2649720A1/fr
Priority claimed from FR8917466A external-priority patent/FR2656530B1/fr
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of PT94680A publication Critical patent/PT94680A/pt
Publication of PT94680B publication Critical patent/PT94680B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0044—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on other nitrogen compounds as donors (1.7)
    • C12N9/0046—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on other nitrogen compounds as donors (1.7) with oxygen as acceptor (1.7.3)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Glass Compositions (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
PT94680A 1989-07-13 1990-07-12 Processo para a obtencao de uma proteina tendo actividade de urato oxidase gene recombinante que a codifica vector de expressao portador deste gene microorganismos procariotas e celulas eucariotas transformados por este vector de expressao PT94680B (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR8909550A FR2649720A1 (en) 1989-07-13 1989-07-13 Recombinant gene which encodes a protein such as urate oxidase
FR8917466A FR2656530B1 (fr) 1989-12-29 1989-12-29 Gene recombinant pour une expression dans les cellules eucaryotes d'une proteine telle que l'urate oxydase.
FR9001368A FR2657785A2 (fr) 1989-12-29 1990-02-06 Gene recombinant pour une expression dans les cellules animales d'une proteine telle que l'urate oxydage.

Publications (2)

Publication Number Publication Date
PT94680A true PT94680A (pt) 1991-04-18
PT94680B PT94680B (pt) 1997-04-30

Family

ID=27251947

Family Applications (1)

Application Number Title Priority Date Filing Date
PT94680A PT94680B (pt) 1989-07-13 1990-07-12 Processo para a obtencao de uma proteina tendo actividade de urato oxidase gene recombinante que a codifica vector de expressao portador deste gene microorganismos procariotas e celulas eucariotas transformados por este vector de expressao

Country Status (24)

Country Link
EP (1) EP0408461B1 (pt)
JP (1) JP2664804B2 (pt)
AT (1) ATE144282T1 (pt)
AU (1) AU636637B2 (pt)
BR (1) BR9006855A (pt)
CA (1) CA2035900C (pt)
DE (2) DE10199042I2 (pt)
DK (1) DK0408461T3 (pt)
ES (1) ES2095243T3 (pt)
FI (1) FI105047B (pt)
GR (1) GR3022085T3 (pt)
HK (1) HK1000099A1 (pt)
HU (1) HU215948B (pt)
IE (1) IE77158B1 (pt)
IL (1) IL95057A (pt)
LU (1) LU90781I2 (pt)
LV (1) LV12000B (pt)
MC (1) MC2145A1 (pt)
NL (1) NL300046I2 (pt)
NO (1) NO2001018I2 (pt)
NZ (1) NZ234453A (pt)
PT (1) PT94680B (pt)
RU (1) RU2105812C1 (pt)
WO (1) WO1991000909A1 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2971218B2 (ja) * 1991-12-04 1999-11-02 協和醗酵工業株式会社 ウリカーゼ遺伝子およびウリカーゼの製造法
US5691188A (en) 1994-02-14 1997-11-25 American Cyanamid Company Transformed yeast cells expressing heterologous G-protein coupled receptor
AU4424497A (en) * 1996-09-13 1998-04-02 Transkaryotic Therapies, Inc. Therapy for alpha-galactosidase a deficiency
US6083725A (en) 1996-09-13 2000-07-04 Transkaryotic Therapies, Inc. Tranfected human cells expressing human α-galactosidase A protein
US6783965B1 (en) * 2000-02-10 2004-08-31 Mountain View Pharmaceuticals, Inc. Aggregate-free urate oxidase for preparation of non-immunogenic polymer conjugates
DK1588716T3 (da) 1998-08-06 2011-05-23 Mountain View Pharmaceuticals Peg-uratoxidase-konjugater og anvendelse deraf
EP1310560A4 (en) 2000-08-17 2005-07-13 Ajinomoto Kk METHOD FOR MODIFICATION OF TRANSGLUTAMINASE OF MICROORGANISMS (MTG)
NZ536361A (en) 2002-04-25 2008-05-30 Shire Human Genetic Therapies Treatment of alpha-galactosidase a deficiency
SI3321359T1 (sl) 2005-04-11 2021-07-30 Horizon Pharma Rheumatology Llc Variantne oblike urat oksidaze in uporaba le-teh
TWI418564B (zh) * 2005-04-11 2013-12-11 Savient Pharmaceuticals Inc 利用陽離子界面活性劑之蛋白質純化
BRPI0612942A2 (pt) 2005-04-11 2012-10-09 Savient Pharmaceuticals Inc forma variante de oxidase de urato e uso do mesmo
US8148123B2 (en) 2005-04-11 2012-04-03 Savient Pharmaceuticals, Inc. Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
JP5033177B2 (ja) * 2006-04-12 2012-09-26 サビエント ファーマセウティカルズ インク． 陽イオン界面活性剤によるタンパク質の精製
RU2443426C2 (ru) * 2008-11-07 2012-02-27 Мунтэн Вью Фармасьютикэлз, Инк. Конъюгаты уратоксидазы, фармацевтическая композиция для снижения уровней мочевой кислоты и способ получения вышеупомянутых конъюгатов
HUP1200205A3 (en) 2009-06-25 2012-09-28 Savient Pharmaceuticals Method and kits for perdicting infusion reaction risk and antibody-mediated low of response by monitoring serum uric acid during pegylated uricare therapy
CN109223707B (zh) * 2018-09-13 2020-12-08 中国药科大学 一种尿酸酶外用凝胶制剂、其制备方法及用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1529675A (fr) * 1967-03-29 1968-06-21 Applic Biochimiques Soc Et Urate oxydase à haute activité et sa préparation
SU457723A1 (ru) * 1973-04-09 1977-08-05 Всесоюзный Научно-Исследовательский Витаминный Институт Штамм 313-152 - продуцент уратоксидазы
EP0423890A3 (en) * 1984-07-27 1991-07-03 Unilever Nv Use of oxidoreductases in bleaching and/or detergent compositions and their preparation by microorganisms engineered by recombinant dna technology
WO1988008450A1 (en) * 1987-05-01 1988-11-03 Birdwell Finlayson Gene therapy for metabolite disorders
JPH0671428B2 (ja) * 1988-08-17 1994-09-14 サッポロビール株式会社 ウリカーゼのｄｎａ配列および製法

Also Published As

Publication number Publication date
CA2035900A1 (fr) 1991-01-14
HU906046D0 (en) 1991-07-29
RU2105812C1 (ru) 1998-02-27
AU636637B2 (en) 1993-05-06
EP0408461A1 (fr) 1991-01-16
ATE144282T1 (de) 1996-11-15
LV12000A (lv) 1998-03-20
BR9006855A (pt) 1991-08-06
DE10199042I2 (de) 2003-10-23
CA2035900C (fr) 2000-01-11
IL95057A (en) 1997-07-13
HU215948B (hu) 1999-03-29
EP0408461B1 (fr) 1996-10-16
PT94680B (pt) 1997-04-30
DK0408461T3 (da) 1997-03-24
DE69028884T2 (de) 1997-05-07
DE69028884D1 (de) 1996-11-21
ES2095243T3 (es) 1997-02-16
NL300046I2 (nl) 2001-12-01
LV12000B (lv) 1998-06-20
IE902559A1 (en) 1991-02-27
FI105047B (fi) 2000-05-31
AU6052390A (en) 1991-02-06
NO2001018I2 (no) 2006-05-01
JPH04501807A (ja) 1992-04-02
IE77158B1 (en) 1997-12-03
FI911212A0 (fi) 1991-03-12
HUT56884A (en) 1991-10-28
IL95057A0 (en) 1991-06-10
NZ234453A (en) 1993-01-27
NL300046I1 (nl) 2001-09-03
HK1000099A1 (en) 1997-11-21
LU90781I2 (fr) 2001-07-23
WO1991000909A1 (fr) 1991-01-24
GR3022085T3 (en) 1997-03-31
JP2664804B2 (ja) 1997-10-22
MC2145A1 (fr) 1992-02-18
DE10199042I1 (de) 2002-01-10

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Effective date: 19901221

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PD3A Change of proprietorship

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Effective date: 20050117

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Effective date: 20120108