NZ234453A - Recombinant dna encoding urate oxidase, and vector, host, protein and pharmaceutical compositions associated therewith - Google Patents
Recombinant dna encoding urate oxidase, and vector, host, protein and pharmaceutical compositions associated therewithInfo
- Publication number
- NZ234453A NZ234453A NZ234453A NZ23445390A NZ234453A NZ 234453 A NZ234453 A NZ 234453A NZ 234453 A NZ234453 A NZ 234453A NZ 23445390 A NZ23445390 A NZ 23445390A NZ 234453 A NZ234453 A NZ 234453A
- Authority
- NZ
- New Zealand
- Prior art keywords
- protein
- vector
- host
- pharmaceutical compositions
- recombinant dna
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0044—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on other nitrogen compounds as donors (1.7)
- C12N9/0046—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on other nitrogen compounds as donors (1.7) with oxygen as acceptor (1.7.3)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Superconductors And Manufacturing Methods Therefor (AREA)
- Peptides Or Proteins (AREA)
- Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
- Glass Compositions (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The invention concerns a new urate oxidase activity protein which has the sequence (I), possibly preceeded by a methionine, or in that it may present a degree of substantial homology with this sequence. The invention is also aimed at medicines containing this protein, as well as the genetic engineering implements to obtain it.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8909550A FR2649720A1 (en) | 1989-07-13 | 1989-07-13 | Recombinant gene which encodes a protein such as urate oxidase |
FR8917466A FR2656530B1 (en) | 1989-12-29 | 1989-12-29 | RECOMBINANT GENE FOR EXPRESSION IN EUKARYOTIC CELLS OF A PROTEIN SUCH AS URATE OXIDASE. |
FR9001368A FR2657785A2 (en) | 1989-12-29 | 1990-02-06 | Recombinant gene for expression of a protein such as urate oxidase in animal cells |
Publications (1)
Publication Number | Publication Date |
---|---|
NZ234453A true NZ234453A (en) | 1993-01-27 |
Family
ID=27251947
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NZ234453A NZ234453A (en) | 1989-07-13 | 1990-07-11 | Recombinant dna encoding urate oxidase, and vector, host, protein and pharmaceutical compositions associated therewith |
Country Status (24)
Country | Link |
---|---|
EP (1) | EP0408461B1 (en) |
JP (1) | JP2664804B2 (en) |
AT (1) | ATE144282T1 (en) |
AU (1) | AU636637B2 (en) |
BR (1) | BR9006855A (en) |
CA (1) | CA2035900C (en) |
DE (2) | DE10199042I2 (en) |
DK (1) | DK0408461T3 (en) |
ES (1) | ES2095243T3 (en) |
FI (1) | FI105047B (en) |
GR (1) | GR3022085T3 (en) |
HK (1) | HK1000099A1 (en) |
HU (1) | HU215948B (en) |
IE (1) | IE77158B1 (en) |
IL (1) | IL95057A (en) |
LU (1) | LU90781I2 (en) |
LV (1) | LV12000B (en) |
MC (1) | MC2145A1 (en) |
NL (1) | NL300046I2 (en) |
NO (1) | NO2001018I2 (en) |
NZ (1) | NZ234453A (en) |
PT (1) | PT94680B (en) |
RU (1) | RU2105812C1 (en) |
WO (1) | WO1991000909A1 (en) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2971218B2 (en) * | 1991-12-04 | 1999-11-02 | 協和醗酵工業株式会社 | Uricase gene and method for producing uricase |
US5691188A (en) | 1994-02-14 | 1997-11-25 | American Cyanamid Company | Transformed yeast cells expressing heterologous G-protein coupled receptor |
US6083725A (en) | 1996-09-13 | 2000-07-04 | Transkaryotic Therapies, Inc. | Tranfected human cells expressing human α-galactosidase A protein |
MX340738B (en) * | 1996-09-13 | 2016-07-22 | Shire Human Genetic Therapies | THERAPY FOR α-GALACTOSIDASE A DEFICIENCY. |
ES2404074T3 (en) | 1998-08-06 | 2013-05-23 | Mountain View Pharmaceuticals, Inc. | Conjugates of urate peg oxidase and its use |
US6783965B1 (en) * | 2000-02-10 | 2004-08-31 | Mountain View Pharmaceuticals, Inc. | Aggregate-free urate oxidase for preparation of non-immunogenic polymer conjugates |
BR0113304A (en) | 2000-08-17 | 2004-01-06 | Ajinomoto Kk | Method for designing and preparing a mutant transglutaminase, mutant mtg mutant transglutaminase, gene, recombinant DNA, microorganisms, method for producing a mutant mtg or mutant transglutaminase, and monocyclic mtg crystals |
ATE514430T1 (en) | 2002-04-25 | 2011-07-15 | Shire Human Genetic Therapies | TREATMENT OF ALPHA-GALACTOSIDASE A DEFICIENCY |
US8148123B2 (en) | 2005-04-11 | 2012-04-03 | Savient Pharmaceuticals, Inc. | Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase |
TWI418564B (en) * | 2005-04-11 | 2013-12-11 | Savient Pharmaceuticals Inc | Purification of proteins with cationic surfactant |
PL215157B1 (en) | 2005-04-11 | 2013-10-31 | Savient Pharmaceuticals | Variant of urate oxidase and its application |
ES2538357T3 (en) | 2005-04-11 | 2015-06-19 | Crealta Pharmaceuticals Llc | Variant forms of urate oxidase and use thereof |
WO2008051178A2 (en) | 2006-04-12 | 2008-05-02 | Savient Pharmaceuticals, Inc. | Purification of proteins with cationic surfactant |
RU2443426C2 (en) * | 2008-11-07 | 2012-02-27 | Мунтэн Вью Фармасьютикэлз, Инк. | Urate oxidase conjugates, pharmaceutical composition for reduction in uric acid levels and method for preparing conjugates stated above |
CZ2011827A3 (en) | 2009-06-25 | 2012-09-26 | Savient Pharmaceuticals, Inc. | Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during PEGylated uricase therapy |
CN109223707B (en) * | 2018-09-13 | 2020-12-08 | 中国药科大学 | Uricase external gel preparation, preparation method and application thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1529675A (en) * | 1967-03-29 | 1968-06-21 | Applic Biochimiques Soc Et | High activity urate oxidase and its preparation |
SU457723A1 (en) * | 1973-04-09 | 1977-08-05 | Всесоюзный Научно-Исследовательский Витаминный Институт | Strain 313-152 actinomyces sp.as producer of uratoxydase |
DE3583194D1 (en) * | 1984-07-27 | 1991-07-18 | Unilever Nv | METHOD FOR THE PRODUCTION OF A POLYPEPTIDE BY MEANS OF A TRANSFORMED MICROORGANISM, A TRANSFORMED MICROORGANISM SUITABLE FOR THIS, AND DNA SEQUENCES SUITABLE FOR THE PRODUCTION OF THESE MICROORGANISMS. |
WO1988008450A1 (en) * | 1987-05-01 | 1988-11-03 | Birdwell Finlayson | Gene therapy for metabolite disorders |
JPH0671428B2 (en) * | 1988-08-17 | 1994-09-14 | サッポロビール株式会社 | Uricase DNA sequence and process |
-
1990
- 1990-07-11 NZ NZ234453A patent/NZ234453A/en unknown
- 1990-07-12 IL IL95057A patent/IL95057A/en active IP Right Grant
- 1990-07-12 PT PT94680A patent/PT94680B/en not_active IP Right Cessation
- 1990-07-13 RU SU4895030/13A patent/RU2105812C1/en active
- 1990-07-13 JP JP2510514A patent/JP2664804B2/en not_active Expired - Lifetime
- 1990-07-13 DE DE2001199042 patent/DE10199042I2/en active Active
- 1990-07-13 WO PCT/FR1990/000532 patent/WO1991000909A1/en active IP Right Grant
- 1990-07-13 BR BR909006855A patent/BR9006855A/en not_active Application Discontinuation
- 1990-07-13 AU AU60523/90A patent/AU636637B2/en not_active Expired
- 1990-07-13 EP EP90402023A patent/EP0408461B1/en not_active Expired - Lifetime
- 1990-07-13 DK DK90402023.7T patent/DK0408461T3/en active
- 1990-07-13 HU HU906046A patent/HU215948B/en active Protection Beyond IP Right Term
- 1990-07-13 IE IE255990A patent/IE77158B1/en not_active IP Right Cessation
- 1990-07-13 ES ES90402023T patent/ES2095243T3/en not_active Expired - Lifetime
- 1990-07-13 MC MC@@@@D patent/MC2145A1/en unknown
- 1990-07-13 AT AT90402023T patent/ATE144282T1/en active
- 1990-07-13 DE DE69028884T patent/DE69028884T2/en not_active Expired - Lifetime
- 1990-07-13 CA CA002035900A patent/CA2035900C/en not_active Expired - Lifetime
-
1991
- 1991-03-12 FI FI911212A patent/FI105047B/en active Protection Beyond IP Right Term
-
1996
- 1996-12-18 GR GR960403531T patent/GR3022085T3/en unknown
-
1997
- 1997-07-08 HK HK97101519A patent/HK1000099A1/en not_active IP Right Cessation
- 1997-10-15 LV LVP-97-200A patent/LV12000B/en unknown
-
2001
- 2001-05-23 LU LU90781C patent/LU90781I2/en unknown
- 2001-06-12 NL NL300046C patent/NL300046I2/en unknown
- 2001-10-30 NO NO2001018C patent/NO2001018I2/en not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RENW | Renewal (renewal fees accepted) |