FI911142A0 - Ett tredimensionellt cell- och vaevnadskultiveringssystem. - Google Patents

Ett tredimensionellt cell- och vaevnadskultiveringssystem.

Info

Publication number
FI911142A0
FI911142A0 FI911142A FI911142A FI911142A0 FI 911142 A0 FI911142 A0 FI 911142A0 FI 911142 A FI911142 A FI 911142A FI 911142 A FI911142 A FI 911142A FI 911142 A0 FI911142 A0 FI 911142A0
Authority
FI
Finland
Prior art keywords
vaevnadskultiveringssystem
tredimensionellt
ett
och
cell
Prior art date
Application number
FI911142A
Other languages
English (en)
Finnish (fi)
Inventor
Gail K Naughton
Brian A Naughton
Original Assignee
Marrow Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/242,096 external-priority patent/US4963489A/en
Application filed by Marrow Tech Inc filed Critical Marrow Tech Inc
Publication of FI911142A0 publication Critical patent/FI911142A0/fi

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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0062General methods for three-dimensional culture
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60Materials for use in artificial skin
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    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0618Cells of the nervous system
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0669Bone marrow stromal cells; Whole bone marrow
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/067Hepatocytes
    • C12N5/0671Three-dimensional culture, tissue culture or organ culture; Encapsulated cells
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0676Pancreatic cells
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0697Artificial constructs associating cells of different lineages, e.g. tissue equivalents
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0697Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • C12N5/0698Skin equivalents
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/08Coculture with; Conditioned medium produced by cells of the nervous system
    • C12N2502/081Coculture with; Conditioned medium produced by cells of the nervous system neurons
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    • C12N2502/08Coculture with; Conditioned medium produced by cells of the nervous system
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    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/09Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
    • C12N2502/091Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells melanocytes
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    • C12N2502/09Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
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    • C12N2502/09Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
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    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/13Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1305Adipocytes
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    • C12N2502/13Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1323Adult fibroblasts
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    • C12N2502/28Vascular endothelial cells
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    • C12N2533/40Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers
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    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/70Polysaccharides

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Botany (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
FI911142A 1988-09-08 1991-03-07 Ett tredimensionellt cell- och vaevnadskultiveringssystem. FI911142A0 (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/242,096 US4963489A (en) 1987-04-14 1988-09-08 Three-dimensional cell and tissue culture system
US07/402,104 US5032508A (en) 1988-09-08 1989-09-01 Three-dimensional cell and tissue culture system
PCT/US1989/003853 WO1990002796A1 (en) 1988-09-08 1989-09-07 Three-dimensional cell and tissue culture system

Publications (1)

Publication Number Publication Date
FI911142A0 true FI911142A0 (fi) 1991-03-07

Family

ID=26934819

Family Applications (1)

Application Number Title Priority Date Filing Date
FI911142A FI911142A0 (fi) 1988-09-08 1991-03-07 Ett tredimensionellt cell- och vaevnadskultiveringssystem.

Country Status (11)

Country Link
US (1) US5032508A (xx)
EP (1) EP0358506A3 (xx)
JP (3) JPH04501657A (xx)
BR (1) BR8907642A (xx)
CA (1) CA1335657C (xx)
DK (1) DK40591A (xx)
FI (1) FI911142A0 (xx)
HU (2) HUT56393A (xx)
NZ (1) NZ230572A (xx)
PT (1) PT91676A (xx)
WO (1) WO1990002796A1 (xx)

Families Citing this family (294)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5032508A (en) * 1988-09-08 1991-07-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
US5902741A (en) * 1986-04-18 1999-05-11 Advanced Tissue Sciences, Inc. Three-dimensional cartilage cultures
US5266480A (en) * 1986-04-18 1993-11-30 Advanced Tissue Sciences, Inc. Three-dimensional skin culture system
US5863531A (en) * 1986-04-18 1999-01-26 Advanced Tissue Sciences, Inc. In vitro preparation of tubular tissue structures by stromal cell culture on a three-dimensional framework
US5567612A (en) * 1986-11-20 1996-10-22 Massachusetts Institute Of Technology Genitourinary cell-matrix structure for implantation into a human and a method of making
US6309635B1 (en) 1986-11-20 2001-10-30 Children's Medical Center Corp. Seeding parenchymal cells into compression resistant porous scaffold after vascularizing in vivo
US5851816A (en) * 1988-06-30 1998-12-22 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Cultured high-fidelity three-dimensional human urogenital tract carcinomas and process
US5496722A (en) * 1988-06-30 1996-03-05 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Method for producing non-neoplastic, three dimensional, mammalian tissue and cell aggregates under microgravity culture conditions and the products produced therefrom
US6117674A (en) * 1988-06-30 2000-09-12 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Pathogen propagation in cultured three-dimensional tissue mass
US5175092A (en) * 1989-05-04 1992-12-29 Millipore Corporation Vitro toxicology kit and method therefor
US5705732A (en) * 1989-06-12 1998-01-06 Oklahoma Medical Research Foundation Universal donor cells
US5635386A (en) * 1989-06-15 1997-06-03 The Regents Of The University Of Michigan Methods for regulating the specific lineages of cells produced in a human hematopoietic cell culture
US5605822A (en) * 1989-06-15 1997-02-25 The Regents Of The University Of Michigan Methods, compositions and devices for growing human hematopoietic cells
CA2062741A1 (en) * 1989-06-15 1990-12-16 Stephen G. Emerson Methods, compositions and devices for growing cells
US5437994A (en) * 1989-06-15 1995-08-01 Regents Of The University Of Michigan Method for the ex vivo replication of stem cells, for the optimization of hematopoietic progenitor cell cultures, and for increasing the metabolism, GM-CSF secretion and/or IL-6 secretion of human stromal cells
US5763266A (en) * 1989-06-15 1998-06-09 The Regents Of The University Of Michigan Methods, compositions and devices for maintaining and growing human stem and/or hematopoietics cells
US5399493A (en) * 1989-06-15 1995-03-21 The Regents Of The University Of Michigan Methods and compositions for the optimization of human hematopoietic progenitor cell cultures
IL95429A (en) * 1989-09-15 1997-09-30 Organogenesis Living tissue equivalents comprising hydrated collagen lattice and a collagen gel and their production
US5061620A (en) * 1990-03-30 1991-10-29 Systemix, Inc. Human hematopoietic stem cell
US5256418A (en) * 1990-04-06 1993-10-26 Organogenesis, Inc. Collagen constructs
US5242806A (en) * 1990-05-07 1993-09-07 Baxter Diagnostics Inc. Method for conducting the cytotoxicity assays on tumor cells
IT1248934B (it) * 1990-06-01 1995-02-11 Fidia Spa Membrane forate biocompatibili,processi per la loro preparazione,loro impiego come supporto per la crescita in vitro di cellule epiteliali, pelli artificiali cosi' ottenute e loro impiego nei trapianti di pelle
EP0470681A3 (en) * 1990-08-08 1992-04-22 W.R. Grace & Co.-Conn. Cell clusters or sheets comprising a plurality of cell species and preparations thereof
DE69133205T2 (de) * 1990-10-19 2003-12-11 New York University, New York Eine methode zur transplantation von zellen in das gehirn und ihre therapeutische verwendung
US5618531A (en) * 1990-10-19 1997-04-08 New York University Method for increasing the viability of cells which are administered to the brain or spinal cord
EP0499932A1 (en) * 1991-02-16 1992-08-26 W.R. Grace & Co.-Conn. Cancer cell cluster comprising cancer cells and normal cells and preparation thereof
US5192312A (en) * 1991-03-05 1993-03-09 Colorado State University Research Foundation Treated tissue for implantation and methods of treatment and use
US6967086B2 (en) * 1991-04-18 2005-11-22 Becton Dickinson And Company Method for determining the presence or absence of respiring cells on a three-dimensional scaffold
EP0513803A2 (en) * 1991-05-17 1992-11-19 Japan Vilene Company, Ltd. Carrier for immobilization of animal cells, process for manufacture thereof, and methods for cultivation
EP0597964A4 (en) * 1991-08-07 1994-11-30 Einstein Coll Med PROLIFERATION OF HEPATOCYTE PRECURSORS.
US6069005A (en) 1991-08-07 2000-05-30 Albert Einstein College Of Medicine Of Yeshwa University Hapatoblasts and method of isolating same
WO1993007913A1 (en) * 1991-10-24 1993-04-29 Children's Medical Center Corporation Neomorphogenesis of urological structures in vivo from cell culture
JP3190042B2 (ja) 1991-10-31 2001-07-16 マトリテク インコーポレイテッド 核マトリックス蛋白液アッセー
JPH07501224A (ja) * 1991-11-25 1995-02-09 コーネル リサーチ ファウンデイション インコーポレイテッド 自動化多区画細胞培養システム
AU3422893A (en) * 1992-01-02 1993-07-28 Regents Of The University Of Michigan, The Methods for regulatory lineages of human hematopoietic cells
US6013853A (en) * 1992-02-14 2000-01-11 The University Of Texas System Continuous release polymeric implant carrier
US5876452A (en) * 1992-02-14 1999-03-02 Board Of Regents, University Of Texas System Biodegradable implant
IT1255657B (it) * 1992-05-29 1995-11-09 Colture di tessuto di mucosa congiuntivale differenziata, procedimentoper la loro preparazione e supporti per il loro uso.
DE69329340T2 (de) * 1992-06-25 2001-02-01 Bernhard M. Babior Aufbewahren von stammzellen
AU4657993A (en) * 1992-06-29 1994-01-24 Alexion Pharmaceuticals, Inc. Matrix for universal donor microvascular endothelial cells
US5800537A (en) * 1992-08-07 1998-09-01 Tissue Engineering, Inc. Method and construct for producing graft tissue from an extracellular matrix
WO1994003584A1 (en) * 1992-08-07 1994-02-17 Tissue Engineering, Inc. Production of graft tissue from extracellular matrix
US5478739A (en) * 1992-10-23 1995-12-26 Advanced Tissue Sciences, Inc. Three-dimensional stromal cell and tissue culture system
US5888720A (en) * 1992-10-27 1999-03-30 Yissum Research And Development Company Of The Hebrew University Of Jerusalem In vitro micro-organs
AU5552794A (en) * 1992-11-25 1994-06-22 Merck & Co., Inc. Hepatic model
US5610007A (en) * 1993-01-21 1997-03-11 Universite Laval Chimeric sheets of epithelial cells
US5656492A (en) * 1993-02-12 1997-08-12 Brigham And Women's Hospital, Inc. Cell induction device
CA2119064A1 (en) * 1993-03-17 1994-09-18 Richard A. Berg Dermal-epidermal in vitro test system
GB9306449D0 (en) 1993-03-29 1993-05-19 Nat Heart Research Fund Tissue equivalents
US6008047A (en) * 1993-04-08 1999-12-28 Livercell L.L.C. Cell culturing method and medium
JP2813467B2 (ja) * 1993-04-08 1998-10-22 ヒューマン・セル・カルチャーズ・インコーポレーテッド 細胞培養法および培地
US5709854A (en) * 1993-04-30 1998-01-20 Massachusetts Institute Of Technology Tissue formation by injecting a cell-polymeric solution that gels in vivo
US5858783A (en) * 1993-05-25 1999-01-12 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Production of normal mammalian organ culture using a medium containing mem-alpha, leibovitz L-15, glucose galactose fructose
AU5116593A (en) * 1993-10-08 1995-05-04 Martin Rosdy In vitro human epidermal sun-tanning test
JPH07298876A (ja) * 1994-03-09 1995-11-14 Res Dev Corp Of Japan 通液性細胞培養担体と、この担体を用いる培養方法お よび培養装置
US5656450A (en) * 1994-05-27 1997-08-12 Board Of Regents, The University Of Texas System Activation of latent transforming growth factor β by matrix vesicles
US20020055786A1 (en) * 1994-08-16 2002-05-09 Anthony Atala Reconstruction of urological structures with polymeric matrices
US5899909A (en) * 1994-08-30 1999-05-04 Medscand Medical Ab Surgical instrument for treating female urinary incontinence
SE506164C2 (sv) * 1995-10-09 1997-11-17 Medscand Medical Ab Instrumentarium för behandling av urininkontinens hos kvinnor
KR970705951A (ko) * 1994-09-12 1997-11-03 가일 케이. 노우톤 심장 판막 구조에서 3차원 사람 세포 배양물과 이의 용도(three-dimensional human cell cultures on cardiac valve franeworks and their uses)
US5562946A (en) * 1994-11-02 1996-10-08 Tissue Engineering, Inc. Apparatus and method for spinning and processing collagen fiber
US7001328B1 (en) 1994-11-15 2006-02-21 Kenton W. Gregory Method for using tropoelastin and for producing tropoelastin biomaterials
US20030152909A1 (en) * 1994-11-16 2003-08-14 Mitrani Eduardo N. In vitro micro-organs, and uses related thereto
US5891558A (en) * 1994-11-22 1999-04-06 Tissue Engineering, Inc. Biopolymer foams for use in tissue repair and reconstruction
US5709934A (en) * 1994-11-22 1998-01-20 Tissue Engineering, Inc. Bipolymer foams having extracellular matrix particulates
US5716404A (en) * 1994-12-16 1998-02-10 Massachusetts Institute Of Technology Breast tissue engineering
US6485723B1 (en) * 1995-02-10 2002-11-26 Purdue Research Foundation Enhanced submucosal tissue graft constructs
US7008634B2 (en) * 1995-03-03 2006-03-07 Massachusetts Institute Of Technology Cell growth substrates with tethered cell growth effector molecules
US6123727A (en) * 1995-05-01 2000-09-26 Massachusetts Institute Of Technology Tissue engineered tendons and ligaments
US5855610A (en) * 1995-05-19 1999-01-05 Children's Medical Center Corporation Engineering of strong, pliable tissues
US6284284B1 (en) 1995-06-06 2001-09-04 Advanced Tissue Sciences, Inc. Compositions and methods for production and use of an injectable naturally secreted extracellular matrix
US5830708A (en) * 1995-06-06 1998-11-03 Advanced Tissue Sciences, Inc. Methods for production of a naturally secreted extracellular matrix
US6129761A (en) 1995-06-07 2000-10-10 Reprogenesis, Inc. Injectable hydrogel compositions
US5741685A (en) * 1995-06-07 1998-04-21 Children's Medical Center Corporation Parenchymal cells packaged in immunoprotective tissue for implantation
US5716413A (en) * 1995-10-11 1998-02-10 Osteobiologics, Inc. Moldable, hand-shapable biodegradable implant material
EP0801676A2 (de) * 1995-10-20 1997-10-22 Michael Sittinger Neue künstliche gewebe, verfahren zu ihrer herstellung und ihre verwendung
US6419920B1 (en) 1995-10-25 2002-07-16 Trans Karyotic Therapies, Inc. Hybrid matrix implants and explants
US5965125A (en) * 1995-10-25 1999-10-12 Transkaryotic Therapies, Inc. Hybrid matrix implants and explants
US5911942A (en) * 1995-11-02 1999-06-15 Tissue Engineering, Inc. Method for spinning and processing collagen fiber
US5800539A (en) * 1995-11-08 1998-09-01 Emory University Method of allogeneic hematopoietic stem cell transplantation without graft failure or graft vs. host disease
US6482231B1 (en) * 1995-11-20 2002-11-19 Giovanni Abatangelo Biological material for the repair of connective tissue defects comprising mesenchymal stem cells and hyaluronic acid derivative
FR2743817B1 (fr) * 1996-01-23 1998-03-13 Oreal Equivalent de peau comprenant des cellules de langerhans
US5842477A (en) * 1996-02-21 1998-12-01 Advanced Tissue Sciences, Inc. Method for repairing cartilage
CN1061812C (zh) * 1996-04-01 2001-02-14 胡杰 制备皮肤移植体的方法
AU2808397A (en) * 1996-04-26 1997-11-19 Case Western Reserve University Skin regeneration using mesenchymal stem cells
EP0915967A1 (en) * 1996-05-28 1999-05-19 The Board Of Regents Of The University Of Michigan Engineering oral tissues
US6213127B1 (en) 1996-07-29 2001-04-10 Emory University Methods for treating cancer using allogeneic lymphocytes without graft vs host disease activity
US5925510A (en) * 1996-10-11 1999-07-20 Cornell Research Foundation, Inc. Medium for preserving tissue without tissue culturing occurring
US6033896A (en) * 1996-11-15 2000-03-07 The Ohio State University Process of separation of cells from liquid by adsorption onto fiber
FR2757635B1 (fr) * 1996-12-24 1999-02-05 Oreal Procede d'evaluation des dommages induits dans la peau par les uv-a
FR2759381B1 (fr) * 1997-02-11 1999-04-16 Oreal Procede d'evaluation du potentiel sensibilisant et/ou irritant et/ou allergene d'un produit
US6039686A (en) 1997-03-18 2000-03-21 Kovac; S. Robert System and a method for the long term cure of recurrent urinary female incontinence
CA2207882A1 (en) 1997-06-17 1998-12-17 Joel Claveau Assessment of human skin damage following exposure to harmful agents
AU9111698A (en) * 1997-09-04 1999-03-22 Pharmacia & Upjohn Company A method for the evaluation of antiviral drugs
US6440734B1 (en) 1998-09-25 2002-08-27 Cytomatrix, Llc Methods and devices for the long-term culture of hematopoietic progenitor cells
GB9720987D0 (en) * 1997-10-01 1997-12-03 Biocure Ltd A multicellular in vitro assay of angiogenesis
US6225118B1 (en) 1997-10-01 2001-05-01 Biocure Limited Multicellular in vitro assay of angiogenesis
EP1032435B1 (en) * 1997-10-31 2003-09-03 Children's Medical Center Corporation Bladder reconstruction
CA2307637C (en) * 1997-10-31 2008-10-07 Children's Medical Center Corporation Penile reconstruction
US7101545B1 (en) 1997-11-26 2006-09-05 Charlotte-Mecklenburg Hospital Authority Method for using human intervertebral disc cells
US6080579A (en) * 1997-11-26 2000-06-27 Charlotte-Mecklenburg Hospital Authority Method for producing human intervertebral disc cells
DE19752900A1 (de) * 1997-11-28 1999-06-02 Biotechnolog Forschung Gmbh Knochenmatrix und/oder osteogene Zellen, deren Verwendung, therapeutische Zubereitung und Kit
US7687057B2 (en) * 1998-01-09 2010-03-30 Yissum Research Development Company Of The Hebrew University Of Jerusalem In vitro micro-organs, and uses related thereto
US6291240B1 (en) 1998-01-29 2001-09-18 Advanced Tissue Sciences, Inc. Cells or tissues with increased protein factors and methods of making and using same
US20020034819A1 (en) * 1998-02-23 2002-03-21 Alan K. Smith Human lineage committed cell composition with enhanced proliferative potential, biological effector function, or both; methods for obtaining same; and their uses
DE19811114C2 (de) * 1998-03-14 2003-08-21 Hellmut Augustin Verfahren zur definierten Herstellung multizellulärer sphäroidaler Aggregate lebender Blutgefäßwandzellen
US6143293A (en) * 1998-03-26 2000-11-07 Carnegie Mellon Assembled scaffolds for three dimensional cell culturing and tissue generation
US6382214B1 (en) * 1998-04-24 2002-05-07 American Medical Systems, Inc. Methods and apparatus for correction of urinary and gynecological pathologies including treatment of male incontinence and female cystocele
CN1115407C (zh) * 1998-11-05 2003-07-23 四川大学华西医院 复合场三维细胞培养装置
US6548299B1 (en) 1999-11-12 2003-04-15 Mark J. Pykett Lymphoid tissue-specific cell production from hematopoietic progenitor cells in three-dimensional devices
AU1720400A (en) * 1998-11-12 2000-05-29 Cell Science Therapeutics, Inc. Lymphoid tissue-specific cell production from hematopoietic progenitor cells in three-dimensional devices
AU769637B2 (en) * 1998-11-19 2004-01-29 Organogenesis Inc. Bioengineered tissue constructs and methods for producing and using them
RU2249039C2 (ru) * 1999-02-04 2005-03-27 Текнион Рисерч Энд Дивелопмент Фаундейшн Лтд. Способ размножения/поддержания недифференцированных гемопоэтических стволовых клеток или клеток-предшественников (варианты), способ приготовления кондиционированной среды стромальных клеток, способ трансплантации недифференцированных гемопоэтических стволовых клеток или клеток-предшественников (варианты)
US20030007954A1 (en) * 1999-04-12 2003-01-09 Gail K. Naughton Methods for using a three-dimensional stromal tissue to promote angiogenesis
US6372494B1 (en) 1999-05-14 2002-04-16 Advanced Tissue Sciences, Inc. Methods of making conditioned cell culture medium compositions
US20040167634A1 (en) * 1999-05-26 2004-08-26 Anthony Atala Prosthetic kidney and its use for treating kidney disease
US7226407B2 (en) 1999-06-09 2007-06-05 Ethicon, Inc. Surgical instrument and method for treating female urinary incontinence
US7121997B2 (en) * 1999-06-09 2006-10-17 Ethicon, Inc. Surgical instrument and method for treating female urinary incontinence
US6932759B2 (en) 1999-06-09 2005-08-23 Gene W. Kammerer Surgical instrument and method for treating female urinary incontinence
DK1581162T3 (da) * 1999-06-09 2011-08-01 Ethicon Inc Indretning til justering af polymerimplantater ved bløde overflader
JP2001037472A (ja) 1999-07-28 2001-02-13 Bio Quest:Kk 三次元細胞培養基材及びそれを用いた細胞培養方法
WO2001014527A1 (en) * 1999-08-23 2001-03-01 Organogenesis Inc. Skin care compositions and treatments
JP2001120582A (ja) * 1999-10-22 2001-05-08 Gunze Ltd 人工心臓弁およびその作製方法
US7799325B2 (en) * 1999-11-05 2010-09-21 Kleinsek Donald A Removal of hypertrophic scars
US20080267923A2 (en) * 1999-11-05 2008-10-30 Donald Kleinsek Hair undifferentiated cells
US6428802B1 (en) 1999-12-29 2002-08-06 Children's Medical Center Corp. Preparing artificial organs by forming polylayers of different cell populations on a substrate
US6376244B1 (en) * 1999-12-29 2002-04-23 Children's Medical Center Corporation Methods and compositions for organ decellularization
US6479064B1 (en) * 1999-12-29 2002-11-12 Children's Medical Center Corporation Culturing different cell populations on a decellularized natural biostructure for organ reconstruction
US6368859B1 (en) 1999-12-29 2002-04-09 Children's Medical Center Corporation Methods and compositions for producing a fascial sling
US6828111B2 (en) 2000-01-13 2004-12-07 Wayne State University Three-dimensional in vitro model of human preneoplastic breast disease
DE10002803A1 (de) * 2000-01-24 2001-08-02 Conbio Lizenzverwertungsgesell System zur internen qualitativen und quantitativen Validierung von Markerindices
US7131943B2 (en) * 2000-03-09 2006-11-07 Ethicon, Inc. Surgical instrument and method for treating organ prolapse conditions
JP4876275B2 (ja) * 2000-03-31 2012-02-15 独立行政法人農業・食品産業技術総合研究機構 生物の組織を薄切した切片からなる動物細胞の培養担体と、この担体を用いる動物細胞の培養方法および移植方法
GB2365443B (en) * 2000-04-04 2004-12-22 Denis Eon Solomon A surgical-medical dressing for the treatment of body burns and for wound healing
DE10019604C2 (de) * 2000-04-20 2002-06-27 Ethicon Gmbh Implantat
JP3421741B2 (ja) * 2000-05-18 2003-06-30 筑波大学長 人工骨髄、血球細胞の増殖方法
JP2004500855A (ja) * 2000-05-31 2004-01-15 フラウンホファー ゲセルシャフトツール フェールデルンク ダー アンゲヴァンテン フォルシュンク エー.ファオ. 感染モデル
JP4426064B2 (ja) * 2000-05-31 2010-03-03 独立行政法人科学技術振興機構 脊椎動物の膵臓のインビトロ形成方法
CN1130971C (zh) * 2000-07-13 2003-12-17 胡杰 制备用作细胞种植框架和植入体的生物细胞外基质的方法
CN1116794C (zh) * 2000-07-13 2003-08-06 胡杰 制备软骨移植体的方法
CN1115957C (zh) * 2000-07-13 2003-07-30 胡杰 制备血管移植体的方法
US7025063B2 (en) 2000-09-07 2006-04-11 Ams Research Corporation Coated sling material
US6641525B2 (en) * 2001-01-23 2003-11-04 Ams Research Corporation Sling assembly with secure and convenient attachment
US6802807B2 (en) 2001-01-23 2004-10-12 American Medical Systems, Inc. Surgical instrument and method
US20020161382A1 (en) * 2001-03-29 2002-10-31 Neisz Johann J. Implant inserted without bone anchors
US7229453B2 (en) * 2001-01-23 2007-06-12 Ams Research Corporation Pelvic floor implant system and method of assembly
US6612977B2 (en) 2001-01-23 2003-09-02 American Medical Systems Inc. Sling delivery system and method of use
US20020147382A1 (en) * 2001-01-23 2002-10-10 Neisz Johann J. Surgical articles and methods
AU2002305444A1 (en) * 2001-05-07 2002-11-18 New York University Microvascular free flaps for local or systemic delivery
US8740987B2 (en) * 2001-06-04 2014-06-03 Warsaw Orthopedic, Inc. Tissue-derived mesh for orthopedic regeneration
US6923939B1 (en) * 2001-07-05 2005-08-02 Uop Llc Heat activated membrane introduction apparatus and method for screening materials
CA2453538A1 (en) * 2001-07-12 2003-01-23 Kyowa Medex Co., Ltd. Method for determination of denatured lipoprotein, reagent for determination of denatured lipoprotein, method for detection of cardiovascular disease, and reagent for detection ofcardiovascular disease
US7407480B2 (en) * 2001-07-27 2008-08-05 Ams Research Corporation Method and apparatus for correction of urinary and gynecological pathologies, including treatment of incontinence cystocele
US6648921B2 (en) 2001-10-03 2003-11-18 Ams Research Corporation Implantable article
US7087065B2 (en) * 2001-10-04 2006-08-08 Ethicon, Inc. Mesh for pelvic floor repair
BR0214217A (pt) * 2001-11-16 2004-09-21 Childrens Medical Center Aumento de função de órgão
CA2466903A1 (en) * 2001-11-19 2003-05-30 Amniotec Inc. Ectocornea-like sheet and method of constructing the same
US20030109036A1 (en) * 2001-12-06 2003-06-12 The Regents Of The University Of California Method for differentiating islet precursor cells into beta cells
MXPA04008407A (es) 2002-03-01 2005-12-12 Ethicon Inc Metodo y aparato para tratar prolapsos de organo pelvico en pacientes femeninas.
WO2003092546A2 (en) * 2002-04-30 2003-11-13 Cook Urological Inc. Sling for supporting tissue
US6943021B2 (en) * 2002-06-07 2005-09-13 Mattek Corporation Three dimensional vaginal tissue model containing immune cells
CN1668734A (zh) * 2002-06-20 2005-09-14 比奥索斯控股有限公司 在生长因子和生物基质或载体结构存在下进行细胞增殖和分化的方法和装置
AU2003242967A1 (en) * 2002-07-12 2004-02-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Method and device for inducing biological processes by micro-organs
IL151660A0 (en) * 2002-09-09 2003-04-10 Univ Ben Gurion Method for isolating and culturing unculturable microorganisms
DE10253066A1 (de) * 2002-11-07 2004-05-27 Co.Don Aktiengesellschaft Gewebeersatzstruktur, Verfahren zur Modifikation einer Gewebeläsion und Verwendung von vorgeformtem dreidimensionalem Gewebe als Lieferant von Botenstoffen und/oder Strukturbausteinen
FR2847268B1 (fr) * 2002-11-19 2006-09-29 Coletica Procede d'identification d'une modification eventuelle d'au moins un parametre biologique mettant en oeuvre des cellules vivantes soumises a un stress et des cellules vivantes non soumises a ce meme stress
US20060141617A1 (en) * 2002-11-19 2006-06-29 The Board Of Trustees Of The University Of Illinois Multilayered microcultures
US20040126405A1 (en) * 2002-12-30 2004-07-01 Scimed Life Systems, Inc. Engineered scaffolds for promoting growth of cells
US7067123B2 (en) * 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
US7744869B2 (en) * 2003-08-20 2010-06-29 Ebi, Llc Methods of treatment using electromagnetic field stimulated mesenchymal stem cells
EP2338441B1 (en) 2003-12-11 2013-01-23 Isto Technologies Inc. Particulate cartilage system
US7771999B2 (en) 2004-04-28 2010-08-10 Vaxdesign Corp. Disease model incorporation into an artificial immune system (AIS)
US8298824B2 (en) 2004-04-28 2012-10-30 Sanofi Pasteur Vaxdesign Corporation Methods of evaluating a test agent in a diseased cell model
US7709256B2 (en) 2004-04-28 2010-05-04 Vaxdesign Corp. Disease model incorporation into an artificial immune system (AIS)
US8030070B2 (en) 2004-04-28 2011-10-04 Sanofi Pasteur Vaxdesign Corp. Artificial lymphoid tissue equivalent
US7785806B2 (en) 2004-04-28 2010-08-31 Vaxdesign Corporation Method for determining the immunogenicity of an antigen
US20060275270A1 (en) * 2004-04-28 2006-12-07 Warren William L In vitro mucosal tissue equivalent
US8071373B2 (en) 2004-04-28 2011-12-06 Sanofi Pasteur Vaxdesign Corp. Co-culture lymphoid tissue equivalent (LTE) for an artificial immune system (AIS)
US7855074B2 (en) 2004-04-28 2010-12-21 Vaxdesign Corp. Artificial immune system: methods for making and use
US7785883B2 (en) 2004-04-28 2010-08-31 Vax Design Corp. Automatable artificial immune system (AIS)
US8047982B2 (en) * 2004-05-07 2011-11-01 Ethicon, Inc. Mesh tape with wing-like extensions for treating female urinary incontinence
US20050288796A1 (en) * 2004-06-23 2005-12-29 Hani Awad Native soft tissue matrix for therapeutic applications
WO2006015031A2 (en) * 2004-07-28 2006-02-09 Ethicon, Inc. Minimally invasive medical implant and insertion device and method for using the same
EP1802742A2 (en) * 2004-08-30 2007-07-04 IKEN Tissue Therapeutics, Inc. Compositions and methods of promoting hair growth
US7527588B2 (en) * 2004-09-15 2009-05-05 Ethicon, Inc. System and method for surgical implant placement
US7837740B2 (en) * 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US20060165667A1 (en) * 2004-12-03 2006-07-27 Case Western Reserve University Novel methods, compositions and devices for inducing neovascularization
US7481314B2 (en) * 2005-02-02 2009-01-27 Ethicon, Inc. Packaging assembly for surgical mesh implants
JP4262695B2 (ja) * 2005-04-25 2009-05-13 独立行政法人海洋研究開発機構 膜状バイオデバイス及びバイオリアクター
WO2007001351A1 (en) * 2005-06-17 2007-01-04 Iken Tissue Therapeutics, Inc. Methods for treating ischemic tissue
US7815926B2 (en) * 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
WO2007016083A1 (en) 2005-07-26 2007-02-08 Ams Research Corporation Methods and systems for treatment of prolapse
FR2889808B1 (fr) 2005-08-17 2011-07-22 Oreal Utilisation de l'acide 8-hexadecene-1,16-dicarboxylique comme agent de soin destine a favoriser la cohesion de la couche cornee
WO2007025290A2 (en) 2005-08-26 2007-03-01 Isto Technologies, Inc. Implants and methods for repair, replacement and treatment of joint disease
WO2007027592A1 (en) * 2005-08-29 2007-03-08 Ams Research Corporation System for positioning support mesh in a patient
CA2623106C (en) 2005-09-19 2013-12-24 Histogenics Corporation Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof
US20090221867A1 (en) * 2005-11-11 2009-09-03 Ams Research Corporation Integral Sling Connection System and Method
JP5113332B2 (ja) * 2005-12-19 2013-01-09 正美 丹羽 血液脳関門インヴィトロ・モデル、病態血液脳関門インヴィトロ・モデル、及びこれを用いた薬物スクリーニング方法、病態血液脳関門機能解析方法、病因解析方法
WO2007075979A2 (en) 2005-12-21 2007-07-05 Vaxdesign Corporation In vitro germinal centers
EP3091071B1 (en) * 2006-03-23 2019-07-03 Pluristem Ltd. Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy
EP2019648A4 (en) 2006-05-19 2017-06-07 AMS Research Corporation Method and articles for treatment of stress urinary incontinence
WO2008012696A2 (en) * 2006-06-15 2008-01-31 Penelope Costello Methods and kits for testing the efficacy of therapeutica compounds and other therapies in a three-dimensional matrix with respect to tumorous cells and tissue
KR101115493B1 (ko) 2006-06-16 2012-03-13 에이엠에스 리써치 코오포레이션 골반질병치료용 임플란트, 도구 및 방법
CA2936752A1 (en) 2006-06-22 2007-12-27 Ams Research Corporation Adjustable tension incontinence sling assemblies
WO2008094178A2 (en) 2006-06-27 2008-08-07 Vaxdesign Corporation Models for vaccine assessment
WO2008062467A2 (en) * 2006-10-13 2008-05-29 Reliance Life Sciences Pvt. Ltd. Cultured melanocytes on biopolymers
WO2008061392A1 (fr) * 2006-11-22 2008-05-29 Hua Liu Procédé de préparation de populations cellulaires présentant une réponse immunitaire antitumorale
US8163549B2 (en) 2006-12-20 2012-04-24 Zimmer Orthobiologics, Inc. Method of obtaining viable small tissue particles and use for tissue repair
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
AU2008240191B2 (en) 2007-04-12 2013-09-19 Zimmer, Inc. Compositions and methods for tissue repair
JP2010528613A (ja) 2007-05-29 2010-08-26 クリストファー ビー. リード, 多能細胞集団を産生する方法およびその使用
US10590391B2 (en) * 2007-06-08 2020-03-17 Wake Forest University Health Sciences Selective cell therapy for the treatment of renal failure
ES2725502T3 (es) * 2007-06-08 2019-09-24 Univ Wake Forest Health Sciences Terapia celular selectiva para el tratamiento de la insuficiencia renal
WO2009048661A1 (en) 2007-07-16 2009-04-16 Vaxdesign Corporation Artificial tissue constructs comprising alveolar cells and methods for using the same
JPWO2009050965A1 (ja) * 2007-10-19 2011-02-24 国立成育医療センター総長 細胞凍結物固定化基材及び初代肝細胞培養ツール、並びに初代肝細胞培養ツールの製造方法
US8623034B2 (en) * 2007-10-19 2014-01-07 Ethicon, Gmbh Soft tissue repair implant
US8524494B2 (en) 2008-01-30 2013-09-03 Histogen, Inc. Low oxygen tension and BFGF generates a multipotent stem cell from a fibroblast in vitro
US20100166824A1 (en) * 2008-01-30 2010-07-01 Histogen, Inc. Extracellular matrix compositions
SG10201906494PA (en) * 2008-01-30 2019-09-27 Histogen Inc Extracellular matrix compositions
US8530415B2 (en) * 2008-01-30 2013-09-10 Histogen, Inc. Repair and/or regeneration of cells with a composition produced by culturing fibroblast cells under hypoxic conditions
US8535913B2 (en) * 2008-01-30 2013-09-17 Histogen, Inc. Soluble composition for promoting hair growth produced by hypoxic culture of fibroblasts cells
EP2265220A1 (en) 2008-03-05 2010-12-29 Musculoskeletal Transplant Foundation Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
PL2288376T3 (pl) 2008-04-18 2016-07-29 Collplant Ltd Sposoby generowania i wykorzystywania prokolagenu
WO2009157585A1 (ja) * 2008-06-24 2009-12-30 独立行政法人海洋研究開発機構 動物細胞の凍結保存用担体、それを用いた凍結保存用バイオデバイス及び凍結保存方法
US8727963B2 (en) 2008-07-31 2014-05-20 Ams Research Corporation Methods and implants for treating urinary incontinence
US9017243B2 (en) 2008-08-25 2015-04-28 Ams Research Corporation Minimally invasive implant and method
US8968181B2 (en) 2008-08-25 2015-03-03 Ams Research Corporation Minimally invasive implant and method
JP5307489B2 (ja) * 2008-09-19 2013-10-02 株式会社クラレ 三次元細胞構造体の作製方法
WO2010056328A1 (en) 2008-11-12 2010-05-20 Tengion, Inc. Isolated renal cells and uses thereof
WO2010057015A1 (en) * 2008-11-14 2010-05-20 Wake Forest University Health Sciences Kidney structures and methods of forming the same
AU2009314506B2 (en) 2008-11-14 2015-07-23 Histogen, Inc. Extracellular matrix compositions for the treatment of cancer
US8449573B2 (en) 2008-12-05 2013-05-28 Boston Scientific Scimed, Inc. Insertion device and method for delivery of a mesh carrier
US20100274362A1 (en) * 2009-01-15 2010-10-28 Avner Yayon Cartilage particle tissue mixtures optionally combined with a cancellous construct
JP5436905B2 (ja) * 2009-03-26 2014-03-05 テルモ株式会社 シート状細胞培養物の製造方法
US8968334B2 (en) 2009-04-17 2015-03-03 Boston Scientific Scimed, Inc. Apparatus for delivering and anchoring implantable medical devices
US9301750B2 (en) * 2009-11-03 2016-04-05 Boston Scientific Scimed, Inc. Device and method for delivery of mesh-based devices
US9060837B2 (en) 2009-11-23 2015-06-23 Ams Research Corporation Patterned sling implant and method
US9060836B2 (en) * 2009-11-23 2015-06-23 Ams Research Corporation Patterned implant and method
JP5667357B2 (ja) * 2009-11-30 2015-02-12 テルモ株式会社 シート状細胞培養物の製造方法
US8622886B2 (en) * 2010-03-16 2014-01-07 Ethicon, Inc. Surgical instrument and method for the treatment of urinary incontinence
KR102428776B1 (ko) 2010-05-12 2022-08-04 인리젠 생물활성 신장 세포
JP5884218B2 (ja) * 2010-06-17 2016-03-15 国立大学法人大阪大学 腫瘍組織モデルの製造方法
US10028813B2 (en) 2010-07-22 2018-07-24 Boston Scientific Scimed, Inc. Coated pelvic implant device and method
WO2012048105A1 (en) 2010-10-06 2012-04-12 Ams Research Corporation Implants with absorbable and non-absorbable features for the treatment of female pelvic conditions
FR2967163A1 (fr) 2010-11-05 2012-05-11 Centre Nat Rech Scient Procede in vitro ou ex vivo pour la maintenance en survie et la generation ou reconstruction d'un epiderme
EP2637711B1 (en) 2010-11-10 2024-03-27 ProKidney Injectable formulations for organ augmentation
EP3527214A1 (en) 2010-11-12 2019-08-21 Allergan, Inc. Metabolized conditioned growth medium and methods of use
US9572648B2 (en) 2010-12-21 2017-02-21 Justin M. Crank Implantable slings and anchor systems
US8597948B2 (en) 2011-03-10 2013-12-03 First Principles, Inc. Cloned biological material medical device and method thereof
US8808162B2 (en) 2011-03-28 2014-08-19 Ams Research Corporation Implants, tools, and methods for treatment of pelvic conditions
US20120253108A1 (en) 2011-03-28 2012-10-04 Fischer Brian G Implants, tools, and methods for treatment of pelvic conditions
US9492259B2 (en) 2011-03-30 2016-11-15 Astora Women's Health, Llc Expandable implant system
FR2976001B1 (fr) 2011-05-30 2014-10-31 Oreal Modele de cuir chevelu reconstruit et procede de screening de molecules actives
US10058240B2 (en) 2011-06-29 2018-08-28 Boston Scientific Scimed, Inc. Systems, implants, tools, and methods for treatments of pelvic conditions
US9351723B2 (en) 2011-06-30 2016-05-31 Astora Women's Health, Llc Implants, tools, and methods for treatments of pelvic conditions
US9414903B2 (en) 2011-07-22 2016-08-16 Astora Women's Health, Llc Pelvic implant system and method
EP2734148B1 (en) 2011-07-22 2019-06-05 Boston Scientific Scimed, Inc. Pelvic implant system
US9492191B2 (en) 2011-08-04 2016-11-15 Astora Women's Health, Llc Tools and methods for treatment of pelvic conditions
US20130035555A1 (en) 2011-08-05 2013-02-07 Alexander James A Systems, implants, tools, and methods for treatment of pelvic conditions
CN102614547B (zh) * 2012-03-13 2015-04-15 中山大学中山眼科中心 一种快速构建复层细胞的方法
WO2013163358A1 (en) 2012-04-24 2013-10-31 Harvard Bioscience, Inc. Engineered tissue scaffolds and supports therefor
JP5977580B2 (ja) * 2012-05-24 2016-08-24 秀実 高橋 ランゲルハンス細胞の調製方法
US20140178343A1 (en) 2012-12-21 2014-06-26 Jian Q. Yao Supports and methods for promoting integration of cartilage tissue explants
WO2014110300A1 (en) 2013-01-09 2014-07-17 Harvard Apparatus Regenerative Technology Synthetic scaffolds
WO2015005349A1 (ja) * 2013-07-09 2015-01-15 国立大学法人東京大学 細胞培養支持体、細胞培養装置、細胞培養キット、及び細胞シート
WO2015017749A1 (en) 2013-08-01 2015-02-05 Mohan P Arun Tissue adjustment implant
US9878071B2 (en) 2013-10-16 2018-01-30 Purdue Research Foundation Collagen compositions and methods of use
JP5813074B2 (ja) * 2013-10-21 2015-11-17 テルモ株式会社 シート状細胞培養物の製造方法
JP6277684B2 (ja) * 2013-11-18 2018-02-14 大日本印刷株式会社 細胞積層体の製造方法
CN104877953B (zh) * 2014-02-28 2018-06-01 上海尚瑞生物医药科技有限公司 促进黑色素细胞色素产生的皮肤制剂的制备方法
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
JP5727665B2 (ja) * 2014-12-11 2015-06-03 テルモ株式会社 シート状細胞培養物の製造方法
JP5893786B2 (ja) * 2015-04-02 2016-03-23 テルモ株式会社 シート状細胞培養物の製造方法
WO2016172365A1 (en) 2015-04-21 2016-10-27 Purdue Research Foundation Office Of Technology Commercialization Cell-collagen-silica composites and methods of making and using the same
RU2587755C1 (ru) * 2015-06-10 2016-06-20 Федеральное государственное бюджетное учреждение "Государственный научный центр Российской Федерации - Федеральный Медицинский биофизический центр имени А.И. Бурназяна Федерального Медико-биологического агентства" (ФГБУ ГНЦ ФМБЦ им. А.И. Бурназяна ФМБА России) Способ получения действующего вещества из пантов марала
GB201510913D0 (en) * 2015-06-22 2015-08-05 Nat University Of Singapore And Agency For Science Technology And Res Vascularized tissue, skin or mucosa quivalent
KR102078602B1 (ko) * 2015-07-23 2020-02-19 한국화학연구원 지방세포와 마크로파지의 3차원 공동 배양 방법
CN107921173B (zh) * 2015-08-03 2021-07-06 富士胶片株式会社 细胞结构体、非人模型动物、非人模型动物的制造方法及被检验物质的评价方法
JP6140322B2 (ja) * 2016-02-24 2017-05-31 テルモ株式会社 シート状細胞培養物の製造方法
CN109072276B (zh) * 2016-04-19 2022-11-01 凸版印刷株式会社 抗癌剂的评价方法
WO2017222065A1 (ja) * 2016-06-24 2017-12-28 株式会社資生堂 三次元培養皮膚シート、その製造に使用するための細胞培養容器及びその製造方法
US11123372B2 (en) 2016-07-29 2021-09-21 Prokidney Bioactive renal cells for the treatment of chronic kidney disease
WO2018200750A1 (en) 2017-04-25 2018-11-01 Purdue Research Foundation 3-dimensional (3d) tissue-engineered muscle for tissue restoration
JP6490738B2 (ja) * 2017-04-28 2019-03-27 テルモ株式会社 シート状細胞培養物の製造方法
JP6915692B2 (ja) * 2017-08-21 2021-08-04 凸版印刷株式会社 抗がん効果の評価方法、及びがん免疫療法の奏効性予測方法
EP3716988A4 (en) * 2017-11-29 2021-12-15 Figene, LLC INTERACTION OF FIBROBLASTS AND IMMUNE CELLS FOR ACTIVATION AND THEIR USES
JP2018078906A (ja) * 2018-01-17 2018-05-24 大日本印刷株式会社 細胞積層体の製造方法
JP2019180354A (ja) * 2018-04-16 2019-10-24 国立研究開発法人理化学研究所 細胞シートの製造方法及び細胞シート
JP6657452B2 (ja) * 2019-02-27 2020-03-04 テルモ株式会社 シート状細胞培養物の製造方法
JP7002497B2 (ja) * 2019-06-20 2022-01-20 テルモ株式会社 シート状細胞培養物の製造方法
JP7556194B2 (ja) * 2019-12-13 2024-09-26 Toppanホールディングス株式会社 細胞構造体及びその使用
JP6872051B2 (ja) * 2020-02-05 2021-05-19 テルモ株式会社 シート状細胞培養物の製造方法
CN112625193B (zh) * 2020-12-31 2022-06-14 青岛科技大学 极性改性凡士林及其制备方法

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH593339A5 (xx) * 1973-07-02 1977-11-30 Monsanto Co
US4144126A (en) * 1975-05-21 1979-03-13 Beecham Group Limited Cell culture method
US4280954A (en) * 1975-07-15 1981-07-28 Massachusetts Institute Of Technology Crosslinked collagen-mucopolysaccharide composite materials
US4016036A (en) * 1975-11-14 1977-04-05 Massachusetts Institute Of Technology Process for serially culturing keratinocytes
US4024020A (en) * 1975-12-15 1977-05-17 Monsanto Company Method of cell culture on polyacrylonitrile surface
DE2557870A1 (de) * 1975-12-22 1977-06-23 Linde Ag Verfahren und vorrichtung zum tiefgefrieren von biologischen substanzen
US4087327A (en) * 1976-04-12 1978-05-02 Monsanto Company Mammalion cell culture process
US4117881A (en) * 1977-06-14 1978-10-03 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration System for and method of freezing biological tissue
US4135975A (en) * 1977-12-14 1979-01-23 Lichtman Marshall A Obtaining human cell lines that elaborate colony stimulating activity for marrow cells of man and other species and methods of preparing same
US4228243A (en) * 1978-07-13 1980-10-14 Toray Industries, Inc. Cell culture propagation apparatus
US4299819A (en) * 1979-01-02 1981-11-10 Sloan-Kettering Institute For Cancer Research Process for treating burn victims
US4342828A (en) * 1979-07-20 1982-08-03 Morinaga Milk Industry Co., Ltd. Method for producing substance capable of stimulating differentiation and proliferation of human granulopoietic stem cells
US4642292A (en) * 1979-10-29 1987-02-10 Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University Method for isolation of connective tissue biomatrix
US4481946A (en) * 1980-08-14 1984-11-13 Altshuler John H Bone marrow transplant method and apparatus
US4486188A (en) * 1980-08-14 1984-12-04 Applied Medical Devices, Inc. Bone marrow transplant method and apparatus
US4553272A (en) * 1981-02-26 1985-11-19 University Of Pittsburgh Regeneration of living tissues by growth of isolated cells in porous implant and product thereof
US4539716A (en) * 1981-03-19 1985-09-10 Massachusetts Institute Of Technology Fabrication of living blood vessels and glandular tissues
US4546500A (en) * 1981-05-08 1985-10-15 Massachusetts Institute Of Technology Fabrication of living blood vessels and glandular tissues
US4489710A (en) * 1981-06-23 1984-12-25 Xoma Corporation Composition and method for transplantation therapy
US4621100A (en) * 1981-09-25 1986-11-04 The Upjohn Company Treatment of osteoporosis with prostaglandins
DE3138597A1 (de) * 1981-09-29 1983-04-14 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur zuechtung von humanen fibrolasten und fibroblastenartigen zellen
US4458678A (en) * 1981-10-26 1984-07-10 Massachusetts Institute Of Technology Cell-seeding procedures involving fibrous lattices
JPS5881781A (ja) * 1981-11-11 1983-05-17 Ajinomoto Co Inc 動物細胞の培養方法
US4485096A (en) * 1982-02-26 1984-11-27 Massachusetts Institute Of Technology Tissue-equivalent and method for preparation thereof
US4520821A (en) * 1982-04-30 1985-06-04 The Regents Of The University Of California Growing of long-term biological tissue correction structures in vivo
US4485097A (en) * 1982-05-26 1984-11-27 Massachusetts Institute Of Technology Bone-equivalent and method for preparation thereof
US4645669A (en) * 1982-10-04 1987-02-24 Albert Einstein College Of Medicine Of Yeshiva University Culturing and emplacement of differentiated cells in vivo
JPS60123884A (ja) * 1983-12-09 1985-07-02 三菱電機株式会社 英語学習機
IL74715A0 (en) * 1984-03-27 1985-06-30 Univ New Jersey Med Biodegradable matrix and methods for producing same
EP0163543A3 (en) * 1984-06-01 1987-08-12 VXR, Inc. Marrow cell stimulator
JPS61227526A (ja) * 1984-07-25 1986-10-09 Chugai Pharmaceut Co Ltd 新規なコロニー刺激因子
US4604346A (en) * 1984-10-09 1986-08-05 Massachusetts Institute Of Technology Skin-equivalent prepared by the use of punch biopsy
AU589438B2 (en) * 1985-08-26 1989-10-12 Hana Biologics, Inc. Transplantable artificial tissue and process
US5032508A (en) * 1988-09-08 1991-07-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
CA1340581C (en) * 1986-11-20 1999-06-08 Joseph P. Vacanti Chimeric neomorphogenesis of organs by controlled cellular implantation using artificial matrices
US4835102A (en) * 1987-03-31 1989-05-30 Eugene Bell Tissue equivalent test systems

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DK40591A (da) 1991-05-07
PT91676A (pt) 1990-03-30
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NZ230572A (en) 1993-12-23
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BR8907642A (pt) 1991-08-20
JP2001258555A (ja) 2001-09-25
CA1335657C (en) 1995-05-23
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