FI114395B - Menetelmä farmakologisesti vaikuttavien tienyylikarboksyylihappojen ja aminoalkoholien estereiden valmistamiseksi ja välituote - Google Patents

Menetelmä farmakologisesti vaikuttavien tienyylikarboksyylihappojen ja aminoalkoholien estereiden valmistamiseksi ja välituote Download PDF

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Publication number
FI114395B
FI114395B FI921087A FI921087A FI114395B FI 114395 B FI114395 B FI 114395B FI 921087 A FI921087 A FI 921087A FI 921087 A FI921087 A FI 921087A FI 114395 B FI114395 B FI 114395B
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FI
Finland
Prior art keywords
thienyl
tropanyl
formula
epoxy
methyl
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Application number
FI921087A
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English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI921087A0 (fi
Inventor
Rolf Banholzer
Richard Reichl
Rudolf Bauer
Original Assignee
Boehringer Ingelheim Pharma
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Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of FI921087A0 publication Critical patent/FI921087A0/fi
Application granted granted Critical
Publication of FI114395B publication Critical patent/FI114395B/fi

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Glass Compositions (AREA)
  • Compositions Of Oxide Ceramics (AREA)
  • Disintegrating Or Milling (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FI921087A 1989-09-16 1992-03-13 Menetelmä farmakologisesti vaikuttavien tienyylikarboksyylihappojen ja aminoalkoholien estereiden valmistamiseksi ja välituote FI114395B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE3931041A DE3931041C2 (de) 1989-09-16 1989-09-16 Ester von Thienylcarbonsäuren mit Aminoalkoholen, ihre Quaternierungsprodukte, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE3931041 1989-09-16
EP9001517 1990-09-08
PCT/EP1990/001517 WO1991004252A1 (de) 1989-09-16 1990-09-08 Neue thienylcarbonsäureester von aminoalkoholen, ihre quaternierungsprodukte sowie die herstellung und verwendung dieser verbindungen

Publications (2)

Publication Number Publication Date
FI921087A0 FI921087A0 (fi) 1992-03-13
FI114395B true FI114395B (fi) 2004-10-15

Family

ID=6389619

Family Applications (1)

Application Number Title Priority Date Filing Date
FI921087A FI114395B (fi) 1989-09-16 1992-03-13 Menetelmä farmakologisesti vaikuttavien tienyylikarboksyylihappojen ja aminoalkoholien estereiden valmistamiseksi ja välituote

Country Status (33)

Country Link
US (1) USRE39820E1 (sk)
EP (1) EP0418716B1 (sk)
JP (1) JPH0730074B2 (sk)
KR (1) KR0168432B1 (sk)
AT (1) ATE103914T1 (sk)
AU (1) AU642913B2 (sk)
BG (1) BG61295B2 (sk)
CA (1) CA2066248C (sk)
CZ (1) CZ284589B6 (sk)
DD (1) DD297647A5 (sk)
DE (3) DE3931041C2 (sk)
DK (1) DK0418716T3 (sk)
ES (1) ES2052125T3 (sk)
FI (1) FI114395B (sk)
HR (1) HRP940723B1 (sk)
HU (2) HU208823B (sk)
IE (1) IE65528B1 (sk)
IL (1) IL95691A (sk)
LU (1) LU90949I2 (sk)
MX (1) MX9203150A (sk)
NL (1) NL300084I2 (sk)
NO (2) NO301478B1 (sk)
NZ (1) NZ235306A (sk)
PH (1) PH31617A (sk)
PL (1) PL168468B1 (sk)
PT (1) PT95312B (sk)
RU (1) RU2073677C1 (sk)
SI (1) SI9011744B (sk)
SK (1) SK452390A3 (sk)
UA (1) UA41272C2 (sk)
WO (1) WO1991004252A1 (sk)
YU (1) YU47800B (sk)
ZA (1) ZA907338B (sk)

Families Citing this family (149)

* Cited by examiner, † Cited by third party
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