FI104788B - Menetelmä pleuromutiliinikompleksin ja farmaseuttisen valmisteen valmistamiseksi - Google Patents

Menetelmä pleuromutiliinikompleksin ja farmaseuttisen valmisteen valmistamiseksi Download PDF

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Publication number
FI104788B
FI104788B FI923342A FI923342A FI104788B FI 104788 B FI104788 B FI 104788B FI 923342 A FI923342 A FI 923342A FI 923342 A FI923342 A FI 923342A FI 104788 B FI104788 B FI 104788B
Authority
FI
Finland
Prior art keywords
cyclodextrin
formula
compound
complex
derivative
Prior art date
Application number
FI923342A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI923342A (fi
FI923342A0 (fi
Inventor
Erich Zeisl
Heinrich Franz Matous
Original Assignee
Biochemie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biochemie Gmbh filed Critical Biochemie Gmbh
Publication of FI923342A0 publication Critical patent/FI923342A0/fi
Publication of FI923342A publication Critical patent/FI923342A/fi
Application granted granted Critical
Publication of FI104788B publication Critical patent/FI104788B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/76—Ring systems containing bridged rings containing three rings containing at least one ring with more than six ring members
    • C07C2603/80—Ring systems containing bridged rings containing three rings containing at least one ring with more than six ring members containing eight-membered rings
    • C07C2603/82—Ring systems containing bridged rings containing three rings containing at least one ring with more than six ring members containing eight-membered rings having three condensed rings with in total fourteen carbon atoms and having a having a [5.4.3.0(1,8)] ring structure, e.g. pleuromutiline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI923342A 1991-07-24 1992-07-22 Menetelmä pleuromutiliinikompleksin ja farmaseuttisen valmisteen valmistamiseksi FI104788B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0147791A AT400674B (de) 1991-07-24 1991-07-24 Pharmazeutische pleuromutilin-zubereitung
AT147791 1991-07-24

Publications (3)

Publication Number Publication Date
FI923342A0 FI923342A0 (fi) 1992-07-22
FI923342A FI923342A (fi) 1993-01-25
FI104788B true FI104788B (fi) 2000-04-14

Family

ID=3514745

Family Applications (1)

Application Number Title Priority Date Filing Date
FI923342A FI104788B (fi) 1991-07-24 1992-07-22 Menetelmä pleuromutiliinikompleksin ja farmaseuttisen valmisteen valmistamiseksi

Country Status (29)

Country Link
US (1) US5578585A (ko)
EP (1) EP0524632B1 (ko)
JP (1) JP3296847B2 (ko)
KR (1) KR100237719B1 (ko)
CN (1) CN1039319C (ko)
AT (2) AT400674B (ko)
AU (1) AU656987B2 (ko)
BG (1) BG61864B1 (ko)
BR (1) BR9202804A (ko)
CA (1) CA2074385C (ko)
CZ (1) CZ281620B6 (ko)
DE (1) DE69221793T2 (ko)
DK (1) DK0524632T3 (ko)
ES (1) ES2104775T3 (ko)
FI (1) FI104788B (ko)
GR (1) GR3025497T3 (ko)
HU (2) HU214589B (ko)
IE (1) IE80625B1 (ko)
IL (1) IL102597A (ko)
MX (1) MX9204318A (ko)
NO (1) NO300445B1 (ko)
NZ (1) NZ243662A (ko)
RO (1) RO111680B1 (ko)
RU (1) RU2099324C1 (ko)
SA (1) SA92130137B1 (ko)
SG (1) SG44633A1 (ko)
SK (1) SK280773B6 (ko)
TW (1) TW307770B (ko)
ZA (1) ZA925600B (ko)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9614017D0 (en) * 1996-07-04 1996-09-04 Biochemie Gmbh Organic compounds
UY25225A1 (es) 1997-10-29 2000-12-29 Smithkline Beecham Plc Derivados de pleuromutilina utiles como agentes antimicrobianos
TWI260220B (en) * 1999-11-22 2006-08-21 Novartis Ag A pharmaceutical composition for the transdermal treatment of bacterial infections in animals
US6866862B2 (en) * 2001-10-05 2005-03-15 Rubicon Scientific Animal feeds including heartworm-prevention drugs
US7052712B2 (en) * 2001-10-05 2006-05-30 Rubicon Scientific Llc Animal feeds including actives and methods of preparing same
US6716448B2 (en) 2001-10-05 2004-04-06 Rubicon Scientific Llc Domesticated household pet food including maintenance amounts of ivermectin
CO5390081A1 (es) * 2001-11-28 2004-04-30 Novartis Ag Compuestos organicos
GB0207495D0 (en) * 2002-03-28 2002-05-08 Biochemie Gmbh Organic compounds
GB0218578D0 (en) * 2002-08-09 2002-09-18 Glaxo Group Ltd Novel method
KR20040027191A (ko) * 2002-09-27 2004-04-01 대한민국 (강원대학교) 콜레스테롤이 감소된 알(卵)의 생산방법
GB0308114D0 (en) * 2003-04-08 2003-05-14 Glaxo Group Ltd Novel compounds
ATE504316T1 (de) 2004-04-01 2011-04-15 Pf Medicament Einschlusskomplexe enthaltend piroxicam, ein cyklodextrin und arginin
EP1686115A1 (de) * 2005-01-26 2006-08-02 Novartis AG Organische Säureadditionssalze von Valnemulin
CN101313011B (zh) * 2005-09-22 2011-03-30 东丽株式会社 聚芳撑硫醚及其制备方法
EP2159220A1 (en) * 2008-09-02 2010-03-03 Nabriva Therapeutics AG Organic compounds
CN102266319B (zh) * 2011-07-25 2012-11-28 武汉回盛生物科技有限公司 一种兽用盐酸沃尼妙林预混剂及其制备方法
CN102764252A (zh) * 2012-08-07 2012-11-07 湖北龙翔药业有限公司 一种盐酸沃尼妙林的用途
US10532102B2 (en) 2016-08-19 2020-01-14 Foresee Pharmaceuticals Co., Ltd. Pharmaceutical composition and methods of uses

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4092424A (en) * 1964-04-17 1978-05-30 Biochemie Ges.M.B.H. Antibiotic derivatives
US4041175A (en) * 1974-05-13 1977-08-09 E. R. Squibb & Sons, Inc. Use of pleuromutilin for the treatment of swine dysentery
US3987194A (en) * 1975-05-12 1976-10-19 E. R. Squibb & Sons, Inc. Use of pleuromutilin derivatives for the treatment of swine dysentery
US4086359A (en) * 1975-09-30 1978-04-25 E. R. Squibb & Sons, Inc. Derivatives of pleuromutilin and compositions
CH627940A5 (de) * 1976-12-23 1982-02-15 Sandoz Ag Kokzidiostatisches kombinationspraeparat.
US4129721A (en) * 1977-12-08 1978-12-12 Eli Lilly And Company A-40104 antibiotics and process for production thereof
US4130709A (en) * 1977-12-08 1978-12-19 Eli Lilly And Company Pleuromutilin glycoside derivatives
DE2966635D1 (en) * 1979-01-12 1984-03-08 Sandoz Ag New pleuromutilin derivatives, their production and pharmaceutical compositions containing them
GB2072012B (en) * 1980-03-14 1984-07-25 Squibb & Sons Inc Veterinary compositions containing pleuromutilin derivatives
JPS58148816A (ja) * 1982-02-27 1983-09-05 Nippon Zenyaku Kogyo Kk 低刺激性チアムリン注射剤
JPS58177949A (ja) * 1982-04-12 1983-10-18 Takeda Chem Ind Ltd ランカシジン群抗生物質包接化合物
JPS5910510A (ja) * 1982-07-08 1984-01-20 Nippon Zenyaku Kogyo Kk 低刺激性チアムリン注射剤
EP0153277B1 (de) * 1984-02-17 1987-08-26 Sandoz Ag Neue Pleuromutilinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung
JPS6191125A (ja) * 1984-10-11 1986-05-09 Nippon Zeon Co Ltd Ｓ−アデノシル−ｌ−メチオニン含有組成物及びその製造法
JPS62120344A (ja) * 1985-11-20 1987-06-01 Nippon Redarii Kk ４−ビフエニリル酢酸エステル−シクロデキストリン包接化合物
JPS62123196A (ja) * 1985-11-22 1987-06-04 Nisshin Flour Milling Co Ltd プレドニゾロン包接化合物
GB8613688D0 (en) * 1986-06-05 1986-07-09 Euro Celtique Sa Pharmaceutical composition
JPS63139130A (ja) * 1986-11-29 1988-06-10 Nippon Funmatsu Yakuhin Kk 長期安定型の漢方薬軟エキスの製造法
JPH0819004B2 (ja) * 1986-12-26 1996-02-28 日清製粉株式会社 徐放性医薬製剤
JPS6463552A (en) * 1987-09-04 1989-03-09 Lederle Japan Ltd 4-biphenylylacetic acid ester-cyclodextrin inclusion compound
CA1321192C (en) * 1988-04-20 1993-08-10 Abdul Majid Inclusion complexes of cyclodextrins by agglomeration
US5007966A (en) * 1988-09-21 1991-04-16 American Maize-Products Company Cyclodextrin complexing method

Also Published As

Publication number Publication date
NO300445B1 (no) 1997-06-02
DE69221793D1 (de) 1997-10-02
JPH05201962A (ja) 1993-08-10
CA2074385C (en) 2003-09-23
BG96678A (bg) 1994-03-24
SK231192A3 (en) 1995-03-08
KR930002378A (ko) 1993-02-23
BG61864B1 (bg) 1998-08-31
DK0524632T3 (da) 1997-09-29
NZ243662A (en) 1994-10-26
IL102597A0 (en) 1993-01-14
HU214589B (hu) 1998-04-28
FI923342A (fi) 1993-01-25
HUT63828A (en) 1993-10-28
BR9202804A (pt) 1994-01-25
KR100237719B1 (ko) 2000-01-15
CN1039319C (zh) 1998-07-29
CA2074385A1 (en) 1993-01-25
EP0524632B1 (en) 1997-08-27
HU9202307D0 (en) 1992-10-28
TW307770B (ko) 1997-06-11
IE80625B1 (en) 1998-10-21
EP0524632A1 (en) 1993-01-27
GR3025497T3 (en) 1998-02-27
AT400674B (de) 1996-02-26
ES2104775T3 (es) 1997-10-16
CZ281620B6 (cs) 1996-11-13
SG44633A1 (en) 1997-12-19
MX9204318A (es) 1994-07-29
FI923342A0 (fi) 1992-07-22
ATA147791A (de) 1995-07-15
US5578585A (en) 1996-11-26
IE922392A1 (en) 1993-01-27
CN1068813A (zh) 1993-02-10
RU2099324C1 (ru) 1997-12-20
DE69221793T2 (de) 1998-03-12
SA92130137B1 (ar) 2005-06-08
NO922901L (no) 1993-01-25
JP3296847B2 (ja) 2002-07-02
SK280773B6 (sk) 2000-07-11
AU656987B2 (en) 1995-02-23
ATE157260T1 (de) 1997-09-15
HU211650A9 (en) 1995-12-28
NO922901D0 (no) 1992-07-22
AU2053692A (en) 1993-01-28
RO111680B1 (ro) 1996-12-30
CZ231192A3 (en) 1993-02-17
IL102597A (en) 1996-06-18
ZA925600B (en) 1994-01-24

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