ES497084A0 - Un procedimiento para preparar nuevos compuestos de tiazol. - Google Patents

Un procedimiento para preparar nuevos compuestos de tiazol.

Info

Publication number
ES497084A0
ES497084A0 ES497084A ES497084A ES497084A0 ES 497084 A0 ES497084 A0 ES 497084A0 ES 497084 A ES497084 A ES 497084A ES 497084 A ES497084 A ES 497084A ES 497084 A0 ES497084 A0 ES 497084A0
Authority
ES
Spain
Prior art keywords
tiazol
compounds
procedure
preparing new
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES497084A
Other languages
English (en)
Other versions
ES8203865A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB10699/77A external-priority patent/GB1600735A/en
Priority claimed from KR7802782A external-priority patent/KR820001285B1/ko
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Priority claimed from KR1019820000231A external-priority patent/KR830000455B1/ko
Publication of ES497084A0 publication Critical patent/ES497084A0/es
Publication of ES8203865A1 publication Critical patent/ES8203865A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/06—1,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES80497084A 1977-03-14 1980-11-24 Un procedimiento para preparar nuevos compuestos de tiazol. Expired ES8203865A1 (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB10699/77A GB1600735A (en) 1977-03-14 1977-03-14 Cephem and cephem compounds and processes for preparation thereof
GB2924577 1977-07-12
GB4231577 1977-10-11
GB7578 1978-01-03
KR7802782A KR820001285B1 (ko) 1977-03-14 1978-09-13 세펨화합물의 제조방법
KR1019820000231A KR830000455B1 (ko) 1977-03-14 1982-01-18 세펨화합물의 제조방법

Publications (2)

Publication Number Publication Date
ES497084A0 true ES497084A0 (es) 1982-04-01
ES8203865A1 ES8203865A1 (es) 1982-04-01

Family

ID=27546433

Family Applications (8)

Application Number Title Priority Date Filing Date
ES467828A Expired ES467828A1 (es) 1977-03-14 1978-03-14 Un procedimiento para preparar nuevos compuestos de cefem y cefam
ES480598A Expired ES480598A1 (es) 1977-03-14 1979-05-16 Procedimiento para preparar acidos 3-cefem (o cefam)-4-car- boxilicos sustituidos en la posicion 7
ES80487737A Expired ES8101077A1 (es) 1977-03-14 1980-01-16 Procedimiento para preparar acidos 3-cefem-4-carboxilicos sustituidos en la posicion 7
ES80487736A Expired ES8100665A1 (es) 1977-03-14 1980-01-16 Procedimiento para preparar acidos 3-cefem-4-carboxilicos sustituidos en la posicion 7.(como divisional de la patente numero 480.598)
ES491182A Granted ES491182A0 (es) 1977-03-14 1980-05-06 Procedimiento para la preparacion de acidos 3-cefem-4-carbo-xilicos sustituidos en la posicion 7
ES80491183A Expired ES8103752A1 (es) 1977-03-14 1980-05-06 Procedimiento para la preparacion de acidos 3-cefem-4-carbo-xilicos sustituidos en la posicion 7
ES80491184A Expired ES8103753A1 (es) 1977-03-14 1980-05-06 Procedimiento para la preparacion de acidos 3-cefem-4-carbo-xilicos sustituidos en la posicion 7
ES80497084A Expired ES8203865A1 (es) 1977-03-14 1980-11-24 Un procedimiento para preparar nuevos compuestos de tiazol.

Family Applications Before (7)

Application Number Title Priority Date Filing Date
ES467828A Expired ES467828A1 (es) 1977-03-14 1978-03-14 Un procedimiento para preparar nuevos compuestos de cefem y cefam
ES480598A Expired ES480598A1 (es) 1977-03-14 1979-05-16 Procedimiento para preparar acidos 3-cefem (o cefam)-4-car- boxilicos sustituidos en la posicion 7
ES80487737A Expired ES8101077A1 (es) 1977-03-14 1980-01-16 Procedimiento para preparar acidos 3-cefem-4-carboxilicos sustituidos en la posicion 7
ES80487736A Expired ES8100665A1 (es) 1977-03-14 1980-01-16 Procedimiento para preparar acidos 3-cefem-4-carboxilicos sustituidos en la posicion 7.(como divisional de la patente numero 480.598)
ES491182A Granted ES491182A0 (es) 1977-03-14 1980-05-06 Procedimiento para la preparacion de acidos 3-cefem-4-carbo-xilicos sustituidos en la posicion 7
ES80491183A Expired ES8103752A1 (es) 1977-03-14 1980-05-06 Procedimiento para la preparacion de acidos 3-cefem-4-carbo-xilicos sustituidos en la posicion 7
ES80491184A Expired ES8103753A1 (es) 1977-03-14 1980-05-06 Procedimiento para la preparacion de acidos 3-cefem-4-carbo-xilicos sustituidos en la posicion 7

Country Status (21)

Country Link
US (7) US4425341A (es)
JP (7) JPS53137988A (es)
AR (2) AR230452A1 (es)
AT (1) AT364456B (es)
BE (1) BE864810A (es)
CA (1) CA1321580C (es)
CH (1) CH637138A5 (es)
CS (1) CS217961B2 (es)
DD (2) DD136839A5 (es)
DE (1) DE2810922C2 (es)
DK (1) DK163832C (es)
ES (8) ES467828A1 (es)
FI (1) FI65779C (es)
FR (1) FR2383951A1 (es)
GR (1) GR63619B (es)
NL (2) NL182401C (es)
NZ (2) NZ186679A (es)
PH (2) PH17188A (es)
PT (1) PT67773A (es)
SE (3) SE438677B (es)
YU (3) YU41586B (es)

Families Citing this family (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE878433A (fr) * 1978-08-31 1980-02-25 Fujisawa Pharmaceutical Co Procede de preparation de derives d'acide 3-cephem-4-carboxylique 3,7-disubstitue, nouveaux produits ainsi obtenus et leur utilisation pour leur activite antibacterienne
FR2399418A1 (fr) * 1977-03-14 1979-03-02 Fujisawa Pharmaceutical Co Procede de preparation d'acides iminoacetiques et nouveaux produits ainsi obtenus, utilises pour la synthese d'acides cepham- ou cephem-carboxyliques
US4464369A (en) * 1977-03-14 1984-08-07 Fujisawa Pharmaceutical Co., Ltd. 7-Acylamino-3-cephem-4-carboxylic acid derivatives and pharmaceutical compositions
US4399133A (en) * 1977-03-14 1983-08-16 Fujisawa Pharmaceutical Company, Limited Cephem compounds
US4409217A (en) 1977-03-14 1983-10-11 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
SE439312B (sv) * 1977-03-25 1985-06-10 Roussel Uclaf Sett att framstella nya oximderivat av 3-acetoximetyl-7-aminotiazolylacetamido cefalosporansyra
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
JPS5498795A (en) * 1978-01-13 1979-08-03 Takeda Chem Ind Ltd Cephalosporin derivative and its preparation
FR2432521A1 (fr) * 1978-03-31 1980-02-29 Roussel Uclaf Nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2421907A1 (fr) * 1978-04-07 1979-11-02 Roussel Uclaf Nouvelles cephalosporines derivees de l'acide 7-/2-(2-amino 4-thiazolyl)2-(carboxymethoxyimino/acetamido 3-substitue cephalosporanique, leur procede de preparation et leur application comme medicaments
US4268509A (en) * 1978-07-10 1981-05-19 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds and processes for preparation thereof
US4284631A (en) * 1978-07-31 1981-08-18 Fujisawa Pharmaceutical Co., Ltd. 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them
US4372952A (en) 1978-07-31 1983-02-08 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US4305937A (en) * 1978-08-17 1981-12-15 Fujisawa Pharmaceutical Co., Ltd. 2-Lower alkyl-7-substituted-2 or 3-cephem-4-carboxylic acid compounds and antibacterial pharmaceutical compositions containing them
FR2453161A1 (fr) * 1978-08-31 1980-10-31 Fujisawa Pharmaceutical Co Procede de preparation de derives d'acide thiazolylacetique et nouveaux produits ainsi obtenus
US4703046A (en) * 1978-09-08 1987-10-27 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds and processes for preparation thereof
US4341775A (en) * 1978-09-11 1982-07-27 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
EP0009671B1 (en) 1978-09-12 1984-06-13 Fujisawa Pharmaceutical Co., Ltd. Starting compounds for preparing cephem compounds and processes for their preparation
DE2945248A1 (de) * 1978-11-13 1980-05-22 Fujisawa Pharmaceutical Co Cephem-verbindungen, verfahren zu ihrer herstellung und sie enthaltende antibakterielle pharmazeutische mittel
FR2444032A2 (fr) * 1978-12-13 1980-07-11 Roussel Uclaf Nouveaux produits derives de l'acide 2-(2-tritylamino-4-thiazolyl) acetique et leur procede de preparation
AU536842B2 (en) * 1978-12-29 1984-05-24 Fujisawa Pharmaceutical Co., Ltd. Cephalosporin antibiotics
FR2448543A1 (fr) * 1979-02-09 1980-09-05 Roussel Uclaf Nouvelles oximes o-substituees par un radical comportant un ammonium quaternaire et derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2461713A1 (fr) * 1979-07-19 1981-02-06 Roussel Uclaf Nouvelles alcoyloximes substituees derivees de l'acide 7-(2-amino 4-thiazolyl) acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
EP0025017A1 (de) * 1979-08-28 1981-03-11 Ciba-Geigy Ag Polyazathiaverbindungen, Verfahren zu ihrer Herstellung, pharmazeutische Präparate enthaltend solche Verbindungen und Verwendung von letzteren
DE3069560D1 (en) * 1979-09-03 1984-12-06 Fujisawa Pharmaceutical Co Cephem compounds, processes for their preparation and pharmaceutical compositions containing them
CH645906A5 (de) * 1979-10-02 1984-10-31 Glaxo Group Ltd Cephalosporinantibiotika.
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
US4409215A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical Co., Ltd. 7-Acylamino-3-substituted cephalosporanic acid derivatives and processes for the preparation thereof
GR78221B (es) 1980-02-01 1984-09-26 Ciba Geigy Ag
FR2476087A1 (fr) * 1980-02-18 1981-08-21 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-alkyloxy ou 3-alkyl-thiomethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
JPS56131591A (en) * 1980-02-20 1981-10-15 Fujisawa Pharmaceut Co Ltd 3,7-disubstituted-3-cephem-4-carboxylic acid compound, its salt, preparation thereof and preventing agent and remedy for microbism containing the same as active consitutent
JPS5726692A (en) * 1980-07-22 1982-02-12 Fujisawa Pharmaceut Co Ltd Preparation of stable crystal of salt of ceftizoxime
DK416681A (da) * 1980-09-26 1982-03-27 Fujisawa Pharmaceutical Co Femgangsmaade til fremstilling af cephemforbindelser
EP0055465B1 (en) * 1980-12-31 1989-08-23 Fujisawa Pharmaceutical Co., Ltd. 7-acylaminocephalosporanic acid derivatives and processes for the preparation thereof
JPS58986A (ja) * 1981-05-07 1983-01-06 Fujisawa Pharmaceut Co Ltd セフェム化合物
JPS57193489A (en) * 1981-05-21 1982-11-27 Fujisawa Pharmaceut Co Ltd Syn-isomer of 7-substituted-3-cephem-4-carboxylic acid ester and its preparation
FR2506307A1 (fr) * 1981-05-22 1982-11-26 Roussel Uclaf Nouveaux derives substitues de l'acide 2-(2-amino 4-thiazolyl) 2-hydroxyimino acetique et leur procede de preparation
US4521413A (en) * 1981-09-14 1985-06-04 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
JPS5849382A (ja) * 1981-09-18 1983-03-23 Kyowa Hakko Kogyo Co Ltd β−ラクタム化合物
JPS5874680A (ja) * 1981-10-01 1983-05-06 Kyowa Hakko Kogyo Co Ltd β−ラクタム化合物
JPS58135872A (ja) * 1981-11-13 1983-08-12 グラクソ・グル−プ・リミテツド 新規な化合物およびその製法
JPS58109477A (ja) * 1981-11-13 1983-06-29 グラクソ・グル−プ・リミテツド 新規な化合物
JPS58135894A (ja) * 1982-01-22 1983-08-12 Fujisawa Pharmaceut Co Ltd ７―置換ブチルアミド―３―ビニルセファロスポラン酸誘導体
JPS58210074A (ja) * 1982-06-02 1983-12-07 Sankyo Co Ltd チアゾ−ル酢酸誘導体およびその製造法
FR2532936A1 (fr) * 1982-09-13 1984-03-16 Roussel Uclaf Nouveaux derives de l'acide 2-amino-thiazolyl-4-yl acetique comportant une fonction oxime substituee et leur procede de preparation
JPS59116291A (ja) * 1982-12-06 1984-07-05 Fujisawa Pharmaceut Co Ltd ７−置換−３−セフエム−４−カルボン酸エステルおよびその製法
EP0115770B2 (en) * 1983-01-07 1996-06-19 Takeda Chemical Industries, Ltd. Thiazole Derivatives
US4480120A (en) * 1983-03-24 1984-10-30 Eastman Kodak Company Process for the preparation of alkyl-2-alkoxyimino-3-oxo-4-chlorobutyrates
GB8318846D0 (en) * 1983-07-12 1983-08-10 Fujisawa Pharmaceutical Co Prophylactic/therapeutic agent against fish diseases
JPS6064986A (ja) * 1983-09-20 1985-04-13 Toyama Chem Co Ltd セファロスポリン類の製造法
GB8406231D0 (en) * 1984-03-09 1984-04-11 Fujisawa Pharmaceutical Co Cephem compounds
AT381496B (de) * 1984-04-10 1986-10-27 Biochemie Gmbh Verfahren zur herstellung von cephalosporinantibiotika
GB8410992D0 (en) * 1984-04-30 1984-06-06 Glaxo Group Ltd Process
GB8410991D0 (en) * 1984-04-30 1984-06-06 Glaxo Group Ltd Process
JPH0645625B2 (ja) * 1984-12-28 1994-06-15 塩野義製薬株式会社 ヒドロキシセフアムカルボン酸エステルの製造法
DK500285A (da) * 1984-11-02 1986-05-03 Glaxo Group Ltd Cephalosporinantibiotika
GB8432295D0 (en) * 1984-12-20 1985-01-30 Fujisawa Pharmaceutical Co Cephem compounds
GB8519606D0 (en) * 1985-08-05 1985-09-11 Fujisawa Pharmaceutical Co 3 7-d substituted-3-cephem compounds
CN86107947A (zh) * 1985-11-22 1987-05-27 藤沢药品工业株式会社 新的头孢烯化合物及其制备方法
JPH0631258B2 (ja) * 1985-11-29 1994-04-27 武田薬品工業株式会社 セフアロスポリン誘導体の製造法
US5373000A (en) * 1985-12-26 1994-12-13 Eisai Co., Ltd. 7Beta-(thiadiazolyl)-2-iminoacetamido-3cephem compounds
EP0238060B1 (en) 1986-03-19 1992-01-08 Banyu Pharmaceutical Co., Ltd. Cephalosporin derivatives, processes for their preparation and antibacterial agents
US4777332A (en) * 1987-06-22 1988-10-11 Tandem Computers Incorporated Apparatus for controlling the connection of an electrical module to an electrical receptacle
JP2003001718A (ja) * 2001-06-20 2003-01-08 Aron Kasei Co Ltd ますの製造方法
WO2004083216A1 (en) * 2003-03-20 2004-09-30 Orchid Chemicals & Pharmaceuticals Ltd A process for the preparation of cephalosporins
WO2013036783A2 (en) 2011-09-09 2013-03-14 Cubist Pharmaceuticals, Inc. Methods for treating intrapulmonary infections
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
CN102993117A (zh) * 2012-11-28 2013-03-27 张家港市大伟助剂有限公司 2-胺基-5-(4-胺基苯基)-噻唑的制备方法
CN102977121A (zh) * 2012-12-25 2013-03-20 菏泽睿智科技开发有限公司 一种头孢唑肟酸的合成方法
US20140274997A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Cephalosporin pharmaceutical compositions
EP2893929B1 (en) 2013-03-15 2025-04-16 Merck Sharp & Dohme LLC Ceftolozane antibiotic compositions
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
AU2014233637A1 (en) 2013-09-09 2015-03-26 Merck Sharp & Dohme Corp. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US20150094293A1 (en) 2013-09-27 2015-04-02 Calixa Therapeutics, Inc. Solid forms of ceftolozane
JP6377570B2 (ja) * 2014-04-28 2018-08-22 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ ２−置換セフェム化合物を含有する医薬組成物
CN105315299B (zh) * 2015-09-22 2017-06-27 盐城开元医药化工有限公司 一种头孢唑肟母核7‑anca的合成方法
CN114105903B (zh) * 2021-12-16 2023-06-27 河北合佳医药科技集团股份有限公司 一种高纯度去甲基氨噻肟酸乙酯的制备方法

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3660396A (en) * 1970-03-04 1972-05-02 Lilly Co Eli Cephalosporin intermediates and process therefor
AR206201A1 (es) * 1972-06-29 1976-07-07 Ciba Geigy Ag Procedimiento para la obtencion de compuestos de acido 7beta-amino-3-cefem-3-01-4-carboxilico0-substituidos
SE428022B (sv) * 1972-06-29 1983-05-30 Ciba Geigy Ag 7beta-amino-cefam-3-on-4-karboxylsyraforeningar till anvendning for framstellning av cefalosporinderivat
AR208068A1 (es) * 1973-02-23 1976-11-30 Lilly Co Eli Un procedimiento para preparar derivados de acidos 7-acilamido-3-halo-cefem-4-carboxilico los esteres y las sales farmaceuticamente aceptables de los mismos
FI65258C (fi) 1973-12-21 1984-04-10 Glaxo Lab Ltd Foerfarande foer framstaellning av en antibiotiskt verkande 7-eta-acylamidocef-3-em-4-karboxylsyra
NZ176206A (en) 1973-12-25 1978-03-06 Takeda Chemical Industries Ltd Cephalosporins
GB1536281A (en) * 1975-06-09 1978-12-20 Takeda Chemical Industries Ltd Cephem compounds
DK154939C (da) 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
AT342197B (de) * 1975-02-20 1978-03-28 Ciba Geigy Ag Neues verfahren zur herstellung von 3-cephemverbindungen
JPS5919114B2 (ja) * 1975-08-25 1984-05-02 武田薬品工業株式会社 セフアロスポリンの製造法
SE440655B (sv) * 1976-01-23 1985-08-12 Roussel Uclaf Sett att framstella nya oximderivat av 7-amino-tiazolyl-acetamido-cefalosporansyra
DE2760123C2 (de) 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
FR2408613A2 (fr) * 1977-07-19 1979-06-08 Roussel Uclaf Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2340093A1 (fr) * 1976-02-05 1977-09-02 Roussel Uclaf Derives de l'acide 3-carbamoyloxymethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
US4299829A (en) * 1976-03-12 1981-11-10 Fujisawa Pharmaceutical Co., Ltd. 2-Lower alkyl-7-substituted-2 or 3-cephem 4-carboxylic acid compounds
FR2345153A1 (fr) * 1976-03-25 1977-10-21 Roussel Uclaf Nouvelles alcoyloximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
US4166115A (en) * 1976-04-12 1979-08-28 Fujisawa Pharmaceutical Co., Ltd. Syn 7-oxoimino substituted derivatives of cephalosporanic acid
US4304770A (en) * 1976-04-12 1981-12-08 Fujisawa Pharmaceutical Co., Ltd. Syn-isomer of 3,7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for the preparation thereof
DK162391C (da) 1976-04-12 1992-03-09 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser
FR2361895A1 (fr) * 1976-08-20 1978-03-17 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-carbamoyloxymethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
JPS6011713B2 (ja) * 1976-09-08 1985-03-27 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
JPS53103493A (en) 1977-02-18 1978-09-08 Takeda Chem Ind Ltd Cephalosporin derivatives and process for their preparation
FR2384779A1 (fr) * 1977-03-25 1978-10-20 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-chloro ou 3-methoxy 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
SE439312B (sv) 1977-03-25 1985-06-10 Roussel Uclaf Sett att framstella nya oximderivat av 3-acetoximetyl-7-aminotiazolylacetamido cefalosporansyra
DE2716677C2 (de) 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephemderivate und Verfahren zu ihrer Herstellung
DE2714880A1 (de) 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
FR2410655A1 (fr) 1977-12-05 1979-06-29 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-substitue 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
US4284631A (en) 1978-07-31 1981-08-18 Fujisawa Pharmaceutical Co., Ltd. 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them
US4379922A (en) * 1978-09-12 1983-04-12 Fujisawa Pharmaceutical Co., Ltd. Cepham compounds
JPS5543011A (en) * 1978-09-20 1980-03-26 Shionogi & Co Ltd 7-halothiazolylalkoxyiminoacetamido-3-cephem compound
FR2448543A1 (fr) 1979-02-09 1980-09-05 Roussel Uclaf Nouvelles oximes o-substituees par un radical comportant un ammonium quaternaire et derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2461713A1 (fr) * 1979-07-19 1981-02-06 Roussel Uclaf Nouvelles alcoyloximes substituees derivees de l'acide 7-(2-amino 4-thiazolyl) acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
JPS56125392A (en) * 1980-03-06 1981-10-01 Fujisawa Pharmaceut Co Ltd Cepham and cephem compound and preparation thereof
JPS6238569A (ja) * 1985-08-13 1987-02-19 Nec Corp 磁気デイスク制御装置
US5059611A (en) * 1988-11-18 1991-10-22 Allergan, Inc. Anti-inflammatory 5-hydroxy-2-furanones

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SE8304670L (sv) 1983-08-29
US4447430A (en) 1984-05-08
DK114878A (da) 1978-09-15
US4460583A (en) 1984-07-17
YU274582A (en) 1983-06-30
YU42061B (en) 1988-04-30
JPS6434974A (en) 1989-02-06
ES8103751A1 (es) 1981-03-16
NL182401C (nl) 1988-03-01
GR63619B (en) 1979-11-27
DE2810922A1 (de) 1978-09-21
AT364456B (de) 1981-10-27
JPH0517230B2 (es) 1993-03-08
SE7802933L (sv) 1978-09-15
ES491183A0 (es) 1981-03-16
JPH03135973A (ja) 1991-06-10
SE438677B (sv) 1985-04-29
YU60878A (en) 1983-04-30
JPH03115288A (ja) 1991-05-16
AR226423A1 (es) 1982-07-15
DE2810922C2 (de) 1985-08-29
US4425341A (en) 1984-01-10
NL182401B (nl) 1987-10-01
BE864810A (fr) 1978-09-13
SE456909B (sv) 1988-11-14
US4822888A (en) 1989-04-18
JPS6134435B2 (es) 1986-08-07
YU41586B (en) 1987-10-31
PH17188A (en) 1984-06-14
ES487736A0 (es) 1980-11-01
ES480598A1 (es) 1980-07-01
ES491184A0 (es) 1981-03-16
FR2383951B1 (es) 1983-02-11
NZ186679A (en) 1982-12-21
PT67773A (en) 1978-04-01
PH17064A (en) 1984-05-24
CS217961B2 (en) 1983-02-25
DD136839A5 (de) 1979-08-01
JPH0720947B2 (ja) 1995-03-08
FR2383951A1 (fr) 1978-10-13
ES487737A0 (es) 1980-12-01
AR230452A1 (es) 1984-04-30
CA1321580C (en) 1993-08-24
CH637138A5 (de) 1983-07-15
JPH03135971A (ja) 1991-06-10
DK163832B (da) 1992-04-06
JPH03135972A (ja) 1991-06-10
JPH03115256A (ja) 1991-05-16
ES8203865A1 (es) 1982-04-01
JPH0639464B2 (ja) 1994-05-25
FI65779C (fi) 1984-07-10
ATA181378A (de) 1981-03-15
JPH052666B2 (es) 1993-01-13
ES8100665A1 (es) 1980-11-01
NL8501475A (nl) 1985-09-02
ES8101077A1 (es) 1980-12-01
FI780801A7 (fi) 1978-09-15
FI65779B (fi) 1984-03-30
YU274682A (en) 1983-10-31
ES491182A0 (es) 1981-03-16
JPS53137988A (en) 1978-12-01
DK163832C (da) 1992-09-21
US4563522A (en) 1986-01-07
NZ199860A (en) 1984-07-31
US4604456A (en) 1986-08-05
US4294960A (en) 1981-10-13
SE8304670D0 (sv) 1983-08-29
ES8103752A1 (es) 1981-03-16
NL7802792A (nl) 1978-09-18
ES467828A1 (es) 1979-09-01
DD144772A5 (de) 1980-11-05
ES8103753A1 (es) 1981-03-16
SE8304671D0 (sv) 1983-08-29

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