JPS56131591A - 3,7-disubstituted-3-cephem-4-carboxylic acid compound, its salt, preparation thereof and preventing agent and remedy for microbism containing the same as active consitutent - Google Patents

3,7-disubstituted-3-cephem-4-carboxylic acid compound, its salt, preparation thereof and preventing agent and remedy for microbism containing the same as active consitutent

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Publication number
JPS56131591A
JPS56131591A JP2481181A JP2481181A JPS56131591A JP S56131591 A JPS56131591 A JP S56131591A JP 2481181 A JP2481181 A JP 2481181A JP 2481181 A JP2481181 A JP 2481181A JP S56131591 A JPS56131591 A JP S56131591A
Authority
JP
Japan
Prior art keywords
salt
microbism
remedy
compound
preventing agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2481181A
Other languages
Japanese (ja)
Inventor
Takao Takatani
Takashi Masugi
Hisashi Takasugi
Hiromu Kawachi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/123,164 external-priority patent/US4331664A/en
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of JPS56131591A publication Critical patent/JPS56131591A/en
Pending legal-status Critical Current

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  • Thiazole And Isothizaole Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:The titled compound of formula I (R1 is amino or protected amino; R2 is carboxy or protecte carboxy; R3 is lower alkanoyloxy, thiadiazolylthio, etc.) and a salt thereof.
EXAMPLE: 7-[ 2-Cyclopentyloxyimino-2-[ 2-( 2,2,2-trifluoroacetamido )thiazol-4-yl ] acetamide]cephalosporanic acid (syn isomer).
USE: A preventing agent and a remedy for microbism active against Gram- positive and Gram-negative bacteria.
PROCESS: A compound of formula II, a reactive derivative at the amino group or salt thereof is reacted with a compound of formula III, a reactive derivative at the carboxy group or a salt thereof in a solvent, e.g. water or acetone, under cooling to at room temperature to give the compound of formula I or a salt thereof.
COPYRIGHT: (C)1981,JPO&Japio
JP2481181A 1980-02-20 1981-02-20 3,7-disubstituted-3-cephem-4-carboxylic acid compound, its salt, preparation thereof and preventing agent and remedy for microbism containing the same as active consitutent Pending JPS56131591A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/123,164 US4331664A (en) 1976-04-12 1980-02-20 Syn isomer of 7-[2-cyclo(lower) alkoxyimino-2-(2-amino-or substituted aminothiazol-4-yl)acetamido]-3-lower alkanoyloxymethyl or heterocyclicthiomethyl-3-cephem-4-carboxylic acid compounds

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP1133925A Division JPH0215073A (en) 1980-02-20 1989-05-25 Thiazoleacetic acid derivative

Publications (1)

Publication Number Publication Date
JPS56131591A true JPS56131591A (en) 1981-10-15

Family

ID=22407070

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2481181A Pending JPS56131591A (en) 1980-02-20 1981-02-20 3,7-disubstituted-3-cephem-4-carboxylic acid compound, its salt, preparation thereof and preventing agent and remedy for microbism containing the same as active consitutent
JP1133925A Pending JPH0215073A (en) 1980-02-20 1989-05-25 Thiazoleacetic acid derivative

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP1133925A Pending JPH0215073A (en) 1980-02-20 1989-05-25 Thiazoleacetic acid derivative

Country Status (1)

Country Link
JP (2) JPS56131591A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011219755A (en) * 2010-04-06 2011-11-04 Infineum Internatl Ltd Lubricating oil composition

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5429971A (en) * 1994-10-03 1995-07-04 United Microelectronics Corporation Method of making single bit erase flash EEPROM

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS549296A (en) * 1977-04-02 1979-01-24 Hoechst Ag Cephem derivative and its preparation
JPS54117493A (en) * 1978-02-15 1979-09-12 Fujisawa Pharmaceut Co Ltd 3,7-disubstituted-3-cephem-4-carboxylic acid compound, its salt, its preparation, and preventives and remedies for microbism consisting mainly of them
JPS5535096A (en) * 1978-09-04 1980-03-11 Fujisawa Pharmaceut Co Ltd 3-cephem compound, its salt, their preparation, and preventive and remedy for microbism comprising thema active constituent

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH17188A (en) * 1977-03-14 1984-06-14 Fujisawa Pharmaceutical Co New cephem and cepham compounds and their pharmaceutical compositions and method of use

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS549296A (en) * 1977-04-02 1979-01-24 Hoechst Ag Cephem derivative and its preparation
JPS54117493A (en) * 1978-02-15 1979-09-12 Fujisawa Pharmaceut Co Ltd 3,7-disubstituted-3-cephem-4-carboxylic acid compound, its salt, its preparation, and preventives and remedies for microbism consisting mainly of them
JPS5535096A (en) * 1978-09-04 1980-03-11 Fujisawa Pharmaceut Co Ltd 3-cephem compound, its salt, their preparation, and preventive and remedy for microbism comprising thema active constituent

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011219755A (en) * 2010-04-06 2011-11-04 Infineum Internatl Ltd Lubricating oil composition

Also Published As

Publication number Publication date
JPH0215073A (en) 1990-01-18

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