JPS56131591A - 3,7-disubstituted-3-cephem-4-carboxylic acid compound, its salt, preparation thereof and preventing agent and remedy for microbism containing the same as active consitutent - Google Patents
3,7-disubstituted-3-cephem-4-carboxylic acid compound, its salt, preparation thereof and preventing agent and remedy for microbism containing the same as active consitutentInfo
- Publication number
- JPS56131591A JPS56131591A JP2481181A JP2481181A JPS56131591A JP S56131591 A JPS56131591 A JP S56131591A JP 2481181 A JP2481181 A JP 2481181A JP 2481181 A JP2481181 A JP 2481181A JP S56131591 A JPS56131591 A JP S56131591A
- Authority
- JP
- Japan
- Prior art keywords
- salt
- microbism
- remedy
- compound
- preventing agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Thiazole And Isothizaole Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:The titled compound of formula I (R1 is amino or protected amino; R2 is carboxy or protecte carboxy; R3 is lower alkanoyloxy, thiadiazolylthio, etc.) and a salt thereof.
EXAMPLE: 7-[ 2-Cyclopentyloxyimino-2-[ 2-( 2,2,2-trifluoroacetamido )thiazol-4-yl ] acetamide]cephalosporanic acid (syn isomer).
USE: A preventing agent and a remedy for microbism active against Gram- positive and Gram-negative bacteria.
PROCESS: A compound of formula II, a reactive derivative at the amino group or salt thereof is reacted with a compound of formula III, a reactive derivative at the carboxy group or a salt thereof in a solvent, e.g. water or acetone, under cooling to at room temperature to give the compound of formula I or a salt thereof.
COPYRIGHT: (C)1981,JPO&Japio
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/123,164 US4331664A (en) | 1976-04-12 | 1980-02-20 | Syn isomer of 7-[2-cyclo(lower) alkoxyimino-2-(2-amino-or substituted aminothiazol-4-yl)acetamido]-3-lower alkanoyloxymethyl or heterocyclicthiomethyl-3-cephem-4-carboxylic acid compounds |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1133925A Division JPH0215073A (en) | 1980-02-20 | 1989-05-25 | Thiazoleacetic acid derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS56131591A true JPS56131591A (en) | 1981-10-15 |
Family
ID=22407070
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2481181A Pending JPS56131591A (en) | 1980-02-20 | 1981-02-20 | 3,7-disubstituted-3-cephem-4-carboxylic acid compound, its salt, preparation thereof and preventing agent and remedy for microbism containing the same as active consitutent |
JP1133925A Pending JPH0215073A (en) | 1980-02-20 | 1989-05-25 | Thiazoleacetic acid derivative |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1133925A Pending JPH0215073A (en) | 1980-02-20 | 1989-05-25 | Thiazoleacetic acid derivative |
Country Status (1)
Country | Link |
---|---|
JP (2) | JPS56131591A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2011219755A (en) * | 2010-04-06 | 2011-11-04 | Infineum Internatl Ltd | Lubricating oil composition |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5429971A (en) * | 1994-10-03 | 1995-07-04 | United Microelectronics Corporation | Method of making single bit erase flash EEPROM |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS549296A (en) * | 1977-04-02 | 1979-01-24 | Hoechst Ag | Cephem derivative and its preparation |
JPS54117493A (en) * | 1978-02-15 | 1979-09-12 | Fujisawa Pharmaceut Co Ltd | 3,7-disubstituted-3-cephem-4-carboxylic acid compound, its salt, its preparation, and preventives and remedies for microbism consisting mainly of them |
JPS5535096A (en) * | 1978-09-04 | 1980-03-11 | Fujisawa Pharmaceut Co Ltd | 3-cephem compound, its salt, their preparation, and preventive and remedy for microbism comprising thema active constituent |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PH17188A (en) * | 1977-03-14 | 1984-06-14 | Fujisawa Pharmaceutical Co | New cephem and cepham compounds and their pharmaceutical compositions and method of use |
-
1981
- 1981-02-20 JP JP2481181A patent/JPS56131591A/en active Pending
-
1989
- 1989-05-25 JP JP1133925A patent/JPH0215073A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS549296A (en) * | 1977-04-02 | 1979-01-24 | Hoechst Ag | Cephem derivative and its preparation |
JPS54117493A (en) * | 1978-02-15 | 1979-09-12 | Fujisawa Pharmaceut Co Ltd | 3,7-disubstituted-3-cephem-4-carboxylic acid compound, its salt, its preparation, and preventives and remedies for microbism consisting mainly of them |
JPS5535096A (en) * | 1978-09-04 | 1980-03-11 | Fujisawa Pharmaceut Co Ltd | 3-cephem compound, its salt, their preparation, and preventive and remedy for microbism comprising thema active constituent |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2011219755A (en) * | 2010-04-06 | 2011-11-04 | Infineum Internatl Ltd | Lubricating oil composition |
Also Published As
Publication number | Publication date |
---|---|
JPH0215073A (en) | 1990-01-18 |
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