ATE18219T1 - Thiazol-derivate und ihre verwendung bei der herstellung von beta-lactam-antibiotika. - Google Patents

Thiazol-derivate und ihre verwendung bei der herstellung von beta-lactam-antibiotika.

Info

Publication number
ATE18219T1
ATE18219T1 AT82306043T AT82306043T ATE18219T1 AT E18219 T1 ATE18219 T1 AT E18219T1 AT 82306043 T AT82306043 T AT 82306043T AT 82306043 T AT82306043 T AT 82306043T AT E18219 T1 ATE18219 T1 AT E18219T1
Authority
AT
Austria
Prior art keywords
beta
lactam antibiotics
manufacture
thiazole derivatives
triphenylmethylaminothiazol
Prior art date
Application number
AT82306043T
Other languages
English (en)
Inventor
William Sutherland Strachan
Alastair Couper Brodie
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE18219T1 publication Critical patent/ATE18219T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
AT82306043T 1981-11-13 1982-11-12 Thiazol-derivate und ihre verwendung bei der herstellung von beta-lactam-antibiotika. ATE18219T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8134359 1981-11-13
EP82306043A EP0088847B1 (de) 1981-11-13 1982-11-12 Thiazol-Derivate und ihre Verwendung bei der Herstellung von Beta-Lactam-Antibiotika

Publications (1)

Publication Number Publication Date
ATE18219T1 true ATE18219T1 (de) 1986-03-15

Family

ID=10525889

Family Applications (1)

Application Number Title Priority Date Filing Date
AT82306043T ATE18219T1 (de) 1981-11-13 1982-11-12 Thiazol-derivate und ihre verwendung bei der herstellung von beta-lactam-antibiotika.

Country Status (5)

Country Link
US (2) US4510312A (de)
EP (1) EP0088847B1 (de)
JP (1) JPS58135872A (de)
AT (1) ATE18219T1 (de)
DE (1) DE3269474D1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0088847B1 (de) * 1981-11-13 1986-02-26 Glaxo Group Limited Thiazol-Derivate und ihre Verwendung bei der Herstellung von Beta-Lactam-Antibiotika
US4426528A (en) * 1982-04-01 1984-01-17 Eli Lilly And Company Purification of syn-(2-aminothiazol-4-yl)methoxyimino)acetic acid
CN103804395B (zh) * 2014-01-16 2015-12-02 天津大学 头孢噻肟钠n,n-二甲基甲酰胺溶剂化合物及制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
US4166115A (en) * 1976-04-12 1979-08-28 Fujisawa Pharmaceutical Co., Ltd. Syn 7-oxoimino substituted derivatives of cephalosporanic acid
PH17188A (en) * 1977-03-14 1984-06-14 Fujisawa Pharmaceutical Co New cephem and cepham compounds and their pharmaceutical compositions and method of use
SE439312B (sv) * 1977-03-25 1985-06-10 Roussel Uclaf Sett att framstella nya oximderivat av 3-acetoximetyl-7-aminotiazolylacetamido cefalosporansyra
AR229883A1 (es) * 1978-05-26 1983-12-30 Glaxo Group Ltd Procedimiento para la preparacion de antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)-acetamido)-3-(1-piridinometil)-cef-3-em-4-carboxilato
EP0088847B1 (de) * 1981-11-13 1986-02-26 Glaxo Group Limited Thiazol-Derivate und ihre Verwendung bei der Herstellung von Beta-Lactam-Antibiotika

Also Published As

Publication number Publication date
DE3269474D1 (en) 1986-04-03
JPH0354661B2 (de) 1991-08-20
US4510312A (en) 1985-04-09
US4670552A (en) 1987-06-02
EP0088847B1 (de) 1986-02-26
JPS58135872A (ja) 1983-08-12
EP0088847A1 (de) 1983-09-21

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee