ES2526295T5 - Compuestos antisentido - Google Patents
Compuestos antisentido Download PDFInfo
- Publication number
- ES2526295T5 ES2526295T5 ES11186113T ES11186113T ES2526295T5 ES 2526295 T5 ES2526295 T5 ES 2526295T5 ES 11186113 T ES11186113 T ES 11186113T ES 11186113 T ES11186113 T ES 11186113T ES 2526295 T5 ES2526295 T5 ES 2526295T5
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- Prior art keywords
- wing
- antisense
- nucleoside
- nucleosides
- modified
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2320/00—Applications; Uses
- C12N2320/50—Methods for regulating/modulating their activity
- C12N2320/53—Methods for regulating/modulating their activity reducing unwanted side-effects
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Applications Claiming Priority (2)
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| US85289406P | 2006-10-18 | 2006-10-18 | |
| US852894P | 2006-10-18 |
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| ES2526295T3 ES2526295T3 (es) | 2015-01-09 |
| ES2526295T5 true ES2526295T5 (es) | 2021-05-04 |
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| US8318496B2 (en) * | 2007-10-04 | 2012-11-27 | Isis Pharmaceuticals, Inc. | Compounds and methods for improving cellular uptake of oligomeric compounds |
| EP2274423A2 (en) | 2008-04-04 | 2011-01-19 | Isis Pharmaceuticals, Inc. | Oligomeric compounds comprising bicyclic nucleosides and having reduced toxicity |
| HUE035888T2 (en) | 2008-10-15 | 2018-05-28 | Ionis Pharmaceuticals Inc | Modulation of Factor 11 Expression |
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| SG10201403841QA (en) | 2009-07-06 | 2014-09-26 | Ontorii Inc | Novel nucleic acid prodrugs and methods of use thereof |
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