EP1163922A3 - Dispenseur à compteur de doses - Google Patents

Dispenseur à compteur de doses Download PDF

Info

Publication number
EP1163922A3
EP1163922A3 EP01118720A EP01118720A EP1163922A3 EP 1163922 A3 EP1163922 A3 EP 1163922A3 EP 01118720 A EP01118720 A EP 01118720A EP 01118720 A EP01118720 A EP 01118720A EP 1163922 A3 EP1163922 A3 EP 1163922A3
Authority
EP
European Patent Office
Prior art keywords
housing
dispenser
container
locatable
dose counter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP01118720A
Other languages
German (de)
English (en)
Other versions
EP1163922A2 (fr
EP1163922B1 (fr
Inventor
Paul Kenneth Rand
Peter John Brand
James William Godfrey
Stanley George Bonney
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9711889.7A external-priority patent/GB9711889D0/en
Priority claimed from GBGB9721875.4A external-priority patent/GB9721875D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Priority to EP04076303A priority Critical patent/EP1475116A3/fr
Publication of EP1163922A2 publication Critical patent/EP1163922A2/fr
Publication of EP1163922A3 publication Critical patent/EP1163922A3/fr
Application granted granted Critical
Publication of EP1163922B1 publication Critical patent/EP1163922B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/009Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0068Indicating or counting the number of dispensed doses or of remaining doses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0068Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/007Mechanical counters
    • A61M15/0071Mechanical counters having a display or indicator
    • A61M15/0076Mechanical counters having a display or indicator on a drum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0068Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/008Electronic counters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0068Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/0081Locking means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0091Inhalators mechanically breath-triggered

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Nozzles (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Medicinal Preparation (AREA)
  • Basic Packing Technique (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
EP01118720A 1997-06-10 1998-06-08 Récipient d'aérosol et distributeur à compteur de doses Expired - Lifetime EP1163922B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP04076303A EP1475116A3 (fr) 1997-06-10 1998-06-08 Distributeur muni d'un compteur de doses

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9711889 1997-06-10
GBGB9711889.7A GB9711889D0 (en) 1997-06-10 1997-06-10 Aerosol dispenser
GB9721875 1997-10-16
GBGB9721875.4A GB9721875D0 (en) 1997-10-16 1997-10-16 Aerosol dispenser
EP98934918A EP0986412B1 (fr) 1997-06-10 1998-06-08 Distributeur muni d'un indicateur de doses

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
EP98934918A Division EP0986412B1 (fr) 1997-06-10 1998-06-08 Distributeur muni d'un indicateur de doses

Related Child Applications (1)

Application Number Title Priority Date Filing Date
EP04076303A Division EP1475116A3 (fr) 1997-06-10 1998-06-08 Distributeur muni d'un compteur de doses

Publications (3)

Publication Number Publication Date
EP1163922A2 EP1163922A2 (fr) 2001-12-19
EP1163922A3 true EP1163922A3 (fr) 2002-10-09
EP1163922B1 EP1163922B1 (fr) 2004-09-01

Family

ID=26311681

Family Applications (5)

Application Number Title Priority Date Filing Date
EP04076303A Withdrawn EP1475116A3 (fr) 1997-06-10 1998-06-08 Distributeur muni d'un compteur de doses
EP98934918A Expired - Lifetime EP0986412B1 (fr) 1997-06-10 1998-06-08 Distributeur muni d'un indicateur de doses
EP01118720A Expired - Lifetime EP1163922B1 (fr) 1997-06-10 1998-06-08 Récipient d'aérosol et distributeur à compteur de doses
EP98932127A Expired - Lifetime EP0988077B1 (fr) 1997-06-10 1998-06-08 Distributeur pourvu d'un compte-doses
EP98932128A Expired - Lifetime EP0988078B1 (fr) 1997-06-10 1998-06-08 Distributeur a compteur de doses

Family Applications Before (2)

Application Number Title Priority Date Filing Date
EP04076303A Withdrawn EP1475116A3 (fr) 1997-06-10 1998-06-08 Distributeur muni d'un compteur de doses
EP98934918A Expired - Lifetime EP0986412B1 (fr) 1997-06-10 1998-06-08 Distributeur muni d'un indicateur de doses

Family Applications After (2)

Application Number Title Priority Date Filing Date
EP98932127A Expired - Lifetime EP0988077B1 (fr) 1997-06-10 1998-06-08 Distributeur pourvu d'un compte-doses
EP98932128A Expired - Lifetime EP0988078B1 (fr) 1997-06-10 1998-06-08 Distributeur a compteur de doses

Country Status (35)

Country Link
US (6) US6360739B1 (fr)
EP (5) EP1475116A3 (fr)
JP (3) JP3487865B2 (fr)
KR (1) KR100493837B1 (fr)
CN (1) CN1150038C (fr)
AP (1) AP1126A (fr)
AR (1) AR012939A1 (fr)
AT (4) ATE215389T1 (fr)
AU (3) AU741218B2 (fr)
BR (3) BR9809554A (fr)
CA (3) CA2293487C (fr)
CO (1) CO4830464A1 (fr)
DE (4) DE69826039T2 (fr)
DK (3) DK0988077T3 (fr)
EA (1) EA001396B1 (fr)
EG (1) EG21520A (fr)
ES (4) ES2227031T3 (fr)
HK (1) HK1023956A1 (fr)
HR (1) HRP980304B1 (fr)
HU (1) HU228280B1 (fr)
ID (1) ID24128A (fr)
IL (1) IL133219A (fr)
IN (1) IN192609B (fr)
IS (1) IS2177B (fr)
MA (1) MA24562A1 (fr)
MY (1) MY124574A (fr)
NO (1) NO331497B1 (fr)
NZ (1) NZ501379A (fr)
PE (1) PE99099A1 (fr)
PL (1) PL188988B1 (fr)
PT (3) PT986412E (fr)
RS (1) RS49632B (fr)
TR (1) TR199903066T2 (fr)
TW (1) TW533865U (fr)
WO (3) WO1998056444A1 (fr)

Families Citing this family (177)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW533865U (en) * 1997-06-10 2003-05-21 Glaxo Group Ltd Dispenser for dispensing medicament and actuation indicating device
EP1449557B1 (fr) * 1998-01-16 2016-09-07 Trudell Medical International Dispositif de distribution en forme de kit
US6082358A (en) * 1998-05-05 2000-07-04 1263152 Ontario Inc. Indicating device for aerosol container
US6729330B2 (en) 1998-05-05 2004-05-04 Trudell Medical International Indicating device for aerosol container
US7436511B2 (en) * 1999-01-22 2008-10-14 Sensys Medical, Inc. Analyte filter method and apparatus
GB2348928B (en) * 1999-04-07 2001-10-31 Bespak Plc Improvements in or relating to dispensing apparatus
GB9917892D0 (en) 1999-07-31 1999-09-29 Glaxo Group Ltd Marking method
GB9918626D0 (en) 1999-08-07 1999-10-13 Glaxo Group Ltd Valve
DE60008402T2 (de) 1999-10-16 2004-07-22 Glaxo Group Ltd., Greenford Gehäuse für ein gerät an einer aerosoldose
GB2360218A (en) * 2000-03-18 2001-09-19 Astrazeneca Uk Ltd Inhaler
JP4652597B2 (ja) * 2000-03-27 2011-03-16 ハイデルベルガー ドルツクマシーネン アクチエンゲゼルシヤフト 枚葉紙処理機械、特に輪転印刷機のための排紙装置
GB2364649A (en) * 2000-05-17 2002-02-06 Orion Corp Inhaler with Dose Counter
TWI224513B (en) * 2000-06-23 2004-12-01 Norton Healthcare Ltd Dose counter for medicament inhaler
EP1357965B1 (fr) * 2001-01-25 2014-09-24 Clinical Designs Limited Inhalateur pour medicament
GB2372542B (en) * 2001-02-23 2003-08-20 Bespak Plc Dosage counting devices
GB2372541B (en) * 2001-02-23 2003-08-20 Bespak Plc Dosage counting devices
US6613010B2 (en) * 2001-04-13 2003-09-02 Penjet Corporation Modular gas-pressured needle-less injector
US6745760B2 (en) 2001-05-15 2004-06-08 Trudell Medical International Medicament applicator
AR036358A1 (es) * 2001-08-28 2004-09-01 Schering Corp Un inhalador de dosis medidas que contiene una formulacion de suspension en aerosol para inhalacion, un proceso para la produccion de la formulacion, el producto y el uso de una formulacion para la manufactura de un medicamento de asma
US7004164B2 (en) * 2002-03-21 2006-02-28 Trudell Medical International Indicating device for aerosol container
US7814900B2 (en) 2002-03-22 2010-10-19 Clinical Designs Limited Can fixture
EP1369139A1 (fr) 2002-06-03 2003-12-10 3M Innovative Properties Company Indicateurs de dose et systèmes de dispension comprenants des nourrisses et des indicateurs
GB0212896D0 (en) * 2002-06-05 2002-07-17 Trumeter Company Ltd Counter
PT1516283E (pt) * 2002-06-21 2009-05-11 Glaxo Group Ltd Indicador de accionamento para um dispositivo de distribuição
GB0216831D0 (en) * 2002-07-19 2002-08-28 Glaxo Group Ltd Medicament dispenser
US6857427B2 (en) * 2002-09-04 2005-02-22 Ric Investments, Inc. Interactive character for use with an aerosol medication delivery system
FR2846453B1 (fr) * 2002-10-28 2005-01-28 Valois Sas Dispositif d'affichage electronique et dispositif de distribution de produit fluide comportant un tel dispositif d'affichage
FR2846308B1 (fr) * 2002-10-28 2006-02-10 Valois Sas Dispositif de distribution de produit fluide avec indicateur de dose
EP1585561A2 (fr) * 2002-10-30 2005-10-19 Glaxo Group Limited Ajutages tubulaires dans des systemes servant a administrer des medicaments
ES2299760T3 (es) * 2002-11-04 2008-06-01 BANG & OLUFSEN MEDICOM A/S Dispositivo de dispensacion.
GB0226022D0 (en) * 2002-11-07 2002-12-18 Corporate Intellectual Propert Device
GB0226021D0 (en) 2002-11-07 2002-12-18 Corporate Intellectual Propert A container
GB0226020D0 (en) 2002-11-07 2002-12-18 Glaxo Group Ltd A holder
US6979668B2 (en) * 2002-12-16 2005-12-27 Generex Pharmaceuticals Incorporated Cleaning compound for and method of cleaning valves and actuators of metered dose dispensers containing pharmaceutical compositions
JP2006511297A (ja) * 2002-12-18 2006-04-06 グラクソ グループ リミテッド ベント型マウスピースを有する投薬システム
GB0301366D0 (en) 2003-01-21 2003-02-19 Glaxo Group Ltd A fixation device
GB0302812D0 (en) * 2003-02-07 2003-03-12 Wickham Mark D Metering valves for dispensers
GB0304000D0 (en) * 2003-02-21 2003-03-26 Clinical Designs Ltd Dispenser
PL1599243T3 (pl) * 2003-03-04 2014-07-31 Norton Healthcare Ltd Urządzenie do dozowania leku z wyświetlaczem wskazującym na stan wewnętrznego zbiornika leku
DE10319646B3 (de) * 2003-05-02 2004-09-02 Hilti Ag Treibmittelbehälter für Setzgeräte und brennkraftbetriebenes Setzgerät
FR2854878B1 (fr) 2003-05-15 2006-03-31 Valois Sas Distributeur de produit fluide.
US7600512B2 (en) * 2003-07-14 2009-10-13 Vortran Medical Technology 1, Inc. Inhaler with breath actuated dose counter
US7703454B2 (en) * 2003-07-14 2010-04-27 Vortran Medical Technology Inhaler with breath actuated dose counter
US20050028815A1 (en) * 2003-07-23 2005-02-10 Deaton Daniel M. Apparatus for electronic dosage counter
GB0321296D0 (en) * 2003-09-11 2003-10-15 Trumeter Company Ltd Counting device
US7621273B2 (en) 2003-10-28 2009-11-24 Trudell Medical International Indicating device with warning dosage indicator
US20070053843A1 (en) * 2003-10-28 2007-03-08 Dawson Michelle L Inhalable pharmaceutical formulations employing lactose anhydrate and methods of administering the same
GB0327112D0 (en) 2003-11-21 2003-12-24 Clincial Designs Ltd Dispenser and reservoir
GB0328635D0 (en) 2003-12-10 2004-01-14 3M Innovative Properties Co Dose counter for dispensers
GB0328502D0 (en) 2003-12-10 2004-01-14 3M Innovative Properties Co Metered dose dispensers and assemblies therefor
GB0328859D0 (en) 2003-12-12 2004-01-14 Clinical Designs Ltd Dispenser and counter
US7100530B2 (en) * 2003-12-15 2006-09-05 Trudell Medical International, Inc. Dose indicating device
BRPI0507714B8 (pt) * 2004-02-16 2021-07-27 Glaxo Group Ltd contador de dose para uso com um dispensador de medicamento, e, dispensador de medicamento
DE102004050468A1 (de) * 2004-03-08 2005-09-29 Friedrich Sanner Gmbh & Co Kg Spritzgusswerk Sprühgerät zur dosierten Abgabe von versprühbaren Stoffen, insbesondere zur Applikation von nicht pulverförmigen pharmazeutischen Wirkstoffen
PL1725285T3 (pl) 2004-03-10 2020-03-31 Glaxo Group Limited Urządzenie dozujące z członem ograniczającym
FR2871450B1 (fr) * 2004-06-14 2006-09-22 Valois Sas Dispositif de distribution de produit fluide
SE0401773D0 (sv) 2004-07-02 2004-07-02 Astrazeneca Ab An inhalation and a method for assemnling said inhalation device
SE0401787D0 (sv) * 2004-07-05 2004-07-05 Astrazeneca Ab Inhaler device counter
SE0401786D0 (sv) 2004-07-05 2004-07-05 Astrazeneca Ab Inhaler device
GB0416801D0 (en) * 2004-07-28 2004-09-01 Reckitt Benckiser Uk Ltd Apparatus and method of using the same
GB2417024B (en) * 2004-08-11 2007-01-03 Bespak Plc Improvements in metering valves for dispensers
DE202005021637U1 (de) 2004-09-04 2009-01-22 Schuckmann, Alfred Von Inhalier-Gerät
WO2006027333A1 (fr) * 2004-09-04 2006-03-16 Alfred Von Schuckmann Inhalateur
US7543582B2 (en) 2004-09-20 2009-06-09 Trudell Medical International Dose indicating device with display elements attached to container
DE102005033398A1 (de) * 2004-11-10 2006-05-11 Alfred Von Schuckmann Inhalier-Gerät
GB0425518D0 (en) 2004-11-19 2004-12-22 Clinical Designs Ltd Substance source
FR2879574B1 (fr) * 2004-12-17 2011-01-21 Valois Sas Dispositif de distribution de produit fluide.
GB0428204D0 (en) 2004-12-23 2005-01-26 Clinical Designs Ltd Medicament container
US7886934B2 (en) 2005-01-20 2011-02-15 Trudell Medical International Dispensing device
NZ556709A (en) 2005-02-10 2009-09-25 Glaxo Group Ltd Process for making lactose utilizing pre-classification techniques and pharmaceutical formulations formed therefrom
US20090029901A1 (en) * 2005-02-10 2009-01-29 Marian Wood-Kaczmar Process for Crystallizing Lactose Particles for Use in Pharmaceutical Formulations
FR2883400B1 (fr) * 2005-03-16 2007-06-15 Valois Sas Dispositif d'indication de doses pour distribuer des produits fluides ou pulverulents
TWI442951B (zh) * 2005-04-14 2014-07-01 Astrazeneca Ab 吸入器計量器
EP1893261A1 (fr) * 2005-05-12 2008-03-05 Kos Life Sciences, Inc. Compteur de doses pour aerosol-doseur
EA012320B1 (ru) 2005-08-24 2009-08-28 Бёрингер Ингельхайм Интернациональ Гмбх Распылитель, включающий счетное устройство и замок, блокирующий его операции
EP1932009B1 (fr) * 2005-08-31 2014-02-12 T2 Biosystems, Inc. Dispositif rmn pour la detection d'analytes
GB0518400D0 (en) 2005-09-09 2005-10-19 Clinical Designs Ltd Dispenser
US20070099883A1 (en) * 2005-10-07 2007-05-03 Cheryl Lynn Calis Anhydrous mometasone furoate formulation
GB2434753B (en) * 2005-11-22 2008-03-12 Bespak Plc Aerosol dispensing apparatus
EP1792660A1 (fr) * 2005-12-02 2007-06-06 Boehringer Ingelheim Pharma GmbH & Co. KG Dispositif distributeur
GB0602049D0 (en) * 2006-02-01 2006-03-15 Trumeter Company Ltd Inhaler
GB0605150D0 (en) 2006-03-14 2006-04-26 Glaxo Group Ltd Counter For Use With A Medicament Dispenser
KR20090003349A (ko) 2006-04-20 2009-01-09 글락소 그룹 리미티드 화합물
EP2010125B1 (fr) * 2006-04-21 2017-01-04 3M Innovative Properties Company Compteur de doses
GB0610541D0 (en) * 2006-05-26 2006-07-05 Bespak Plc Improvements in or relating to dispensing apparatus
GB2448839B (en) 2006-05-26 2009-05-27 Consort Medical Plc Improvements in or relating to dispensing apparatus
GB0611587D0 (en) 2006-06-12 2006-07-19 Glaxo Group Ltd Novel compounds
US20070295329A1 (en) * 2006-06-13 2007-12-27 Lieberman Eric A Dose indicator
US8141550B2 (en) 2006-08-01 2012-03-27 Trudell Medical International Dispensing device
WO2008067254A2 (fr) * 2006-11-27 2008-06-05 Abbott Respiratory Llc Procédé et dispositif de distribution nasale de médicament
JP4828403B2 (ja) * 2006-12-28 2011-11-30 株式会社吉野工業所 薬剤放出器具
GB2448112B (en) * 2007-01-16 2011-08-17 Bespak Plc Improvements in or relating to dispensing apparatus
US7836880B2 (en) * 2007-01-17 2010-11-23 Kevin Innocenzi Pressurized metered dose inhaler system
US20080210231A1 (en) * 2007-01-31 2008-09-04 Abbott Laboratories Metered dose inhaler cleaning method and apparatus
GB0706405D0 (en) * 2007-04-02 2007-05-09 3M Innovative Properties Co Dose counter
DE102007045438B4 (de) * 2007-09-22 2016-09-01 Boehringer Ingelheim International Gmbh Inhalier-Gerät
US8082873B2 (en) 2008-05-05 2011-12-27 Trudell Medical International Drive mechanism for an indicating device
US8181591B1 (en) 2008-05-23 2012-05-22 Trudell Medical International Domed actuator for indicating device
JP5088795B2 (ja) * 2008-05-30 2012-12-05 株式会社吉野工業所 液体吐出器
JP5502858B2 (ja) 2008-06-05 2014-05-28 グラクソ グループ リミテッド Pi3キナーゼの阻害剤として有用な4−カルボキサミドインダゾール誘導体
AU2009269117A1 (en) * 2008-07-11 2010-01-14 Map Pharmaceuticals, Inc. Containers for aerosol drug delivery
DE102008044770A1 (de) * 2008-08-28 2010-03-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Antriebseinheit für Dosiszähler
US20100139653A1 (en) * 2008-10-01 2010-06-10 Judy Schloss Ventilator interface
CA2905402C (fr) 2008-10-22 2017-02-28 Trudell Medical International Systeme modulaire d'administration d'aerosol
NZ574666A (en) 2009-02-05 2009-04-30 Nexus6 Ltd A medicament inhaler holder that uses optical means to count and display the number of doses used
EP2406255B1 (fr) 2009-03-09 2015-04-29 Glaxo Group Limited 4-oxadiazol-2-yl-indazoles en tant qu'inhibiteurs des pi3 kinases
JP2012520257A (ja) 2009-03-10 2012-09-06 グラクソ グループ リミテッド Ikk2阻害剤としてのインドール誘導体
GB0904040D0 (en) 2009-03-10 2009-04-22 Euro Celtique Sa Counter
GB0904059D0 (en) 2009-03-10 2009-04-22 Euro Celtique Sa Counter
JP2012520845A (ja) 2009-03-17 2012-09-10 グラクソ グループ リミテッド Itk阻害剤として使用されるピリミジン誘導体
CN102439151A (zh) 2009-03-19 2012-05-02 默沙东公司 使用短干扰核酸(siNA)的RNA干扰介导的BTB和CNC同系物1,碱性亮氨酸拉链转录因子1(Bach1)基因表达的抑制
EP2408458A1 (fr) 2009-03-19 2012-01-25 Merck Sharp&Dohme Corp. INHIBITION INDUITE PAR ARN INTERFÉRENCE DE L'EXPRESSION DU GÈNE TRANSDUCTEUR DE SIGNAL ET ACTIVITATEUR DE TRANSCRIPTION 6 (STAT6) AU MOYEN D'UN ACIDE NUCLÉIQUE INTERFÉRENT COURT (ANsi)
EP2408916A2 (fr) 2009-03-19 2012-01-25 Merck Sharp&Dohme Corp. Inhibition médiée par arn interférence de l'expression génique de facteur de croissance de tissu conjonctif (ctgf) en utilisant un acide nucléique interférant court (ansi)
US20120029054A1 (en) 2009-03-19 2012-02-02 Merck Sharp & Dohme Corp. RNA Interference Mediated Inhibition of GATA Binding Protein 3 (GATA3) Gene Expression Using Short Intefering Nucleic Acid (siNA)
US20120004282A1 (en) 2009-03-27 2012-01-05 Merck Sharp & Dohme Corp, RNA Interference Mediated Inhibition of the Intercellular Adhesion Molecule 1 (ICAM-1) Gene Expression Using Short Interfering Nucleic Acid (siNA)
US20120010272A1 (en) 2009-03-27 2012-01-12 Merck Sharp & Dohme Corp. RNA Interference Mediated Inhibition of Apoptosis Signal-Regulating Kinase 1 (ASK1) Gene Expression Using Short Interfering Nucleic Acid (siNA)
JP2012521762A (ja) 2009-03-27 2012-09-20 メルク・シャープ・エンド・ドーム・コーポレイション 低分子干渉核酸(siNA)を用いた神経成長因子β鎖(NGFβ)遺伝子発現のRNA干渉媒介性阻害
EP2411520A2 (fr) 2009-03-27 2012-02-01 Merck Sharp&Dohme Corp. Inhibition à médiation par l'interférence arn de l'expression du gène de la lymphopoïétine stromale thymique (tslp) faisant appel à de courts acides nucléiques interférents (ansi)
US20120022142A1 (en) 2009-03-27 2012-01-26 Merck Sharp & Dohme Corp. RNA Interference Mediated Inhibition of Signal Transducer and Activator of Transcription 1 (STAT1) Gene Expression Using Short Interfering Nucleic Acid (siNA)
ES2530445T3 (es) 2009-03-30 2015-03-02 Arven Ilac Sanayi Ve Ticaret As Un contador para un dispositivo inhalador de polvo seco
ES2876933T3 (es) 2009-04-30 2021-11-15 Glaxo Group Ltd Indazoles sustituidos con oxazol como inhibidores de PI3-cinasas
LT3210644T (lt) * 2009-05-27 2019-02-11 Ino Therapeutics Llc Įrenginiai, skirti sugraduoto vožtuvo ir hermetiško kanistro įrenginio sukabinimui be sandariklio
SI2459260T1 (sl) * 2009-07-30 2014-12-31 Ivax International B.V. Ĺ tevec odmerkov za inhalator z merjenimi odmerki
US9216261B2 (en) 2009-07-30 2015-12-22 Ivax International B.V. Dose counter for a metered-dose inhaler
AU2013224758B2 (en) * 2009-07-30 2016-05-12 Ivax International B.V. Dose counter for a metered-dose inhaler
US8539945B2 (en) * 2009-08-18 2013-09-24 Teva Pharmaceutical Industries Ltd. Dose counter and recording method
GB2473070B (en) * 2009-09-01 2011-09-28 Consort Medical Plc Dispensing apparatus
GB0920499D0 (en) 2009-11-23 2010-01-06 3M Innovative Properties Co Dose counter
EP2507226A1 (fr) 2009-12-03 2012-10-10 Glaxo Group Limited Nouveaux composés
EP2507223A1 (fr) 2009-12-03 2012-10-10 Glaxo Group Limited Dérivés de benzpyrazole comme inhibiteurs des pi3 kinases
US20120238571A1 (en) 2009-12-03 2012-09-20 Glaxo Group Limited Indazole derivatives as pi 3-kinase
GB0921555D0 (en) 2009-12-09 2010-01-27 3M Innovative Properties Co Dose indicator
WO2011110575A1 (fr) 2010-03-11 2011-09-15 Glaxo Group Limited Dérivés de 2-[2-(benzo- ou pyrido-)thiazolylamino]-6- aminopyridine, utiles dans le traitement de maladies respiratoires, allergiques ou inflammatoires
KR101618935B1 (ko) * 2010-05-18 2016-05-09 아이박스 파마슈티컬즈 아일랜드 흡입기용 용량 계수기, 흡입기 및 그의 샤프트
WO2012032067A1 (fr) 2010-09-08 2012-03-15 Glaxo Group Limited Polymorphes et sels de n-[5-[4-(5-{[(2r,6s-2,6-diméthyl-4-morpholinyl]- méthyl}-1,3-oxazol-2-yl)-1h-indazol-6-yl]-2-(méthyloxy)-3-pyridinyl]- méthanesulfonamide
US9326987B2 (en) 2010-09-08 2016-05-03 Glaxo Group Limited Indazole derivatives for use in the treatment of influenza virus infection
WO2012035055A1 (fr) 2010-09-17 2012-03-22 Glaxo Group Limited Nouveaux composés
GB201018124D0 (en) 2010-10-27 2010-12-08 Glaxo Group Ltd Polymorphs and salts
WO2012150427A1 (fr) 2011-05-04 2012-11-08 Cipla Limited Compteur de doses
NZ595367A (en) 2011-09-23 2012-02-24 Nexus6 Ltd A dose counting mechanism adapted to enclose a medicament delivery device
GB201118845D0 (en) 2011-11-01 2011-12-14 Euro Celtique Sa Dispenser
RU2014128386A (ru) 2012-02-06 2016-03-27 ГлаксоСмитКлайн Интеллекчуал Проперти (N 2) Лимитед Ингибиторы PI3K для лечения кашля
ES2609126T3 (es) 2012-07-26 2017-04-18 Glaxo Group Limited 2-(Azaindol-2-il)benzimidazoles como inhibidores de PAD4
US9872964B2 (en) 2012-08-22 2018-01-23 Presspart Gmbh & Co. Kg Metered dose inhaler counter and metered-dose inhaler including such a counter
US10034988B2 (en) 2012-11-28 2018-07-31 Fontem Holdings I B.V. Methods and devices for compound delivery
MX2015006457A (es) 2012-11-30 2015-08-14 Hoffmann La Roche Inhibidores de la tirosina cinasa de bruton.
US8807131B1 (en) 2013-06-18 2014-08-19 Isonea Limited Compliance monitoring for asthma inhalers
US10194693B2 (en) 2013-09-20 2019-02-05 Fontem Holdings 1 B.V. Aerosol generating device
JP6494634B2 (ja) 2013-09-22 2019-04-03 キャリター・サイエンシーズ・リミテッド・ライアビリティ・カンパニーCalitor Sciences, Llc 置換されているアミノピリミジン化合物および使用方法
EP3057587A1 (fr) 2013-10-17 2016-08-24 GlaxoSmithKline Intellectual Property Development Limited Inhibiteur de pi3k pour le traitement d'une maladie respiratoire
JP6475707B2 (ja) 2013-10-17 2019-02-27 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited 呼吸器疾患の治療のためのpi3k阻害剤
BR112016023983B1 (pt) * 2014-05-07 2022-10-18 Boehringer Ingelheim International Gmbh Contentor para um nebulizador, nebulizador para um fluido e método para conectar um contentor a um dispositivo indicador
US10722666B2 (en) * 2014-05-07 2020-07-28 Boehringer Ingelheim International Gmbh Nebulizer with axially movable and lockable container and indicator
WO2016059645A1 (fr) * 2014-10-14 2016-04-21 Cadila Healthcare Limited Compteur de doses
EP3212212B1 (fr) 2014-10-31 2020-09-23 Monash University Formulation de poudre
EP4186548A1 (fr) 2015-04-02 2023-05-31 Hill-Rom Services PTE. LTD. Détection de fuite de masque pour un dispositif respiratoire
BR112017024678A2 (pt) 2015-05-21 2018-07-31 Glaxosmithkline Intellectual Property Development Limited derivados de benzoimidazol como inibidores de pad4
CA2991138A1 (fr) 2015-07-20 2017-01-26 Daniel Deaton Systemes de distribution d'aerosol et methodes associees
EP3377045A1 (fr) 2015-11-18 2018-09-26 Glaxosmithkline Intellectual Property (No. 2) Limited Compositions pharmaceutiques à base de ribavirine
WO2017127731A1 (fr) 2016-01-21 2017-07-27 T2 Biosystems, Inc. Méthodes et systèmes de détection rapide de bactéries
GB201602527D0 (en) 2016-02-12 2016-03-30 Glaxosmithkline Ip Dev Ltd Chemical compounds
GB201610450D0 (en) 2016-06-15 2016-07-27 Tech Partnership The Plc Counting mechanism
US20190161480A1 (en) 2016-08-08 2019-05-30 Glaxosmithkline Intellectual Property Development Limited Chemical Compounds
EP3300753B1 (fr) 2016-09-30 2018-12-12 Presspart Gmbh & Co. Kg Inhalateur de dose mesuree destine a administrer des doses d'aerosols
GB201706102D0 (en) 2017-04-18 2017-05-31 Glaxosmithkline Ip Dev Ltd Chemical compounds
GB201712081D0 (en) 2017-07-27 2017-09-13 Glaxosmithkline Ip Dev Ltd Chemical compounds
MX2020007521A (es) 2018-01-17 2022-12-05 Glaxosmithkline Ip Dev Ltd Inhibidores de pi4kiii.
EP3740468A4 (fr) 2018-01-20 2021-10-06 Sunshine Lake Pharma Co., Ltd. Composés d'aminopyrimidine substitués et procédés d'utilisation
US11291182B2 (en) * 2018-02-05 2022-04-05 Nexfeed LLP Device for facilitating and tracking the feeding of an animal
WO2019215471A1 (fr) * 2018-05-11 2019-11-14 Biocorp Production S.A. Inhalateur doseur portatif
US20240119250A1 (en) * 2019-10-04 2024-04-11 Lupin Limited Event Status Apparatuses and Related Devices, Systems, and Methods
FR3108536B1 (fr) * 2020-03-30 2022-06-17 Aptar France Sas Dispositif de distribution de produit fluide, en particulier pour un nombre limité de doses
CN111977192B (zh) * 2020-09-14 2022-01-07 孟庆萍 一种药丸定量倒出装置
US11142391B1 (en) * 2020-10-15 2021-10-12 Ac Avalanche Llc Dispenser for pressurized canister
WO2022179967A1 (fr) 2021-02-23 2022-09-01 Glaxosmithkline Intellectual Property (No.2) Limited Vadadustat pour le traitement de la covid-19 chez un sujet hospitalisé
KR20240003479A (ko) * 2022-07-01 2024-01-09 주식회사 케이티앤지 인헤일러
CN117205413B (zh) * 2023-11-07 2024-02-13 正大天晴(广州)医药有限公司 一种剂量指示装置

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992017231A1 (fr) * 1991-03-28 1992-10-15 Innomed, Inc. Inhalateur microelectronique possedant un compteur et un minuteur
US5228586A (en) * 1990-08-31 1993-07-20 Ing. Erich Pfeiffer Gmbh & Co. Kg Media dispenser with removable use index
US5289946A (en) * 1990-08-31 1994-03-01 Ing. Erich Pfeiffer Gmbh & Co. Kg Dispenser for media
US5349945A (en) * 1990-11-26 1994-09-27 Minnesota Mining And Manufacturing Company Aerosol dispenser comprising an indicator assembly

Family Cites Families (135)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB893717A (en) 1960-02-23 1962-04-11 Syncro Mist Controls Inc Fluid control valve actuator device
US3119557A (en) * 1961-10-05 1964-01-28 United States Steel Corp Counter operator for pressurized paint can
US3212718A (en) 1964-04-23 1965-10-19 Edward H Green Indicating plate for spray canisters
CH444761A (fr) * 1965-12-10 1968-02-29 Ebauches Sa Dispositif magnétique d'entraînement pour l'horlogerie
US3361306A (en) 1966-03-31 1968-01-02 Merck & Co Inc Aerosol unit dispensing uniform amounts of a medically active ingredient
US3487886A (en) 1967-07-20 1970-01-06 Joseph Sunnen Means for indicating the remaining contents of a container
NL7003794A (fr) 1969-03-20 1970-09-22
DE1954623B2 (de) 1969-10-30 1973-02-15 Siemens AG, 1000 Berlin u 8000 München Ziffernsteller unter verwendung magnetfeldabhaengiger widerstaende
GB1317315A (en) 1970-12-17 1973-05-16 English Numbering Machines Mechanical impulse counter
US3722461A (en) * 1972-07-07 1973-03-27 Sutra Import Corp Scoring counter
GB1392945A (en) 1972-08-23 1975-05-07 Fisons Ltd Inhalation device
US3822808A (en) * 1973-03-20 1974-07-09 Tokico Ltd Fuel supplying apparatus having a reversible plate type flow indicator
US4037719A (en) * 1976-06-01 1977-07-26 Alan Perlmutter Cigarette counting case
US4106503A (en) 1977-03-11 1978-08-15 Richard R. Rosenthal Metering system for stimulating bronchial spasm
DE2725876C2 (de) * 1977-06-08 1982-11-25 J. Hengstler Kg, 7209 Aldingen Umspuleinrichtung mit Filmbildzähler
DE2735117A1 (de) 1977-08-04 1979-02-15 Hengstler Kg Steckvorrichtung
US4160900A (en) 1978-01-11 1979-07-10 General Motors Corporation Mileage switch and latch means
DE7817128U1 (de) 1978-06-08 1978-09-21 J. Hengstler Kg, 7209 Aldingen Tastenrueckstelleinrichtung mit rueckstellrechen
DE2827315C2 (de) 1978-06-22 1985-01-17 J. Hengstler Kg, 7209 Aldingen Einstellvorrichtung für drehrückstellbare Vorwahlzähler
DE2828907C2 (de) 1978-06-30 1982-03-25 J. Hengstler Kg, 7209 Aldingen Vorwählbarer Einstellzähler mit stehendem Einstellrollenwerk und einer über Nocken axial wirkenden Signaleinrichtung
US4311050A (en) * 1979-08-27 1982-01-19 Bessman Samuel P Reservoir for medicaments
GB2063075B (en) 1979-11-07 1983-11-09 Sterwin Ag Dose indicator for inhalers
DE3047491A1 (de) 1980-12-17 1982-07-15 J. Hengstler Kg, 7209 Aldingen Vorwaehlbarer zaehler
AT377110B (de) 1981-10-29 1985-02-11 Mattig Kg Anton Elektromechanisches zaehlwerk
GB2114790A (en) 1981-12-18 1983-08-24 Trumeter Company Limited Bi-directional prescaling counter
DE3203137C2 (de) * 1982-01-30 1986-05-22 J. Hengstler Kg, 7209 Aldingen Nullstellvorrichtung für ein Rollenzählwerk
DE3244836C2 (de) 1982-12-03 1984-09-27 Bosch-Siemens Hausgeräte GmbH, 7000 Stuttgart Inhaliervorrichtung mit einer Dosiereinrichtung für Inhalate
DE3302160A1 (de) * 1983-01-22 1984-07-26 Ing. Erich Pfeiffer GmbH & Co KG, 7760 Radolfzell Betaetigbare dosiereinrichtung
US4495944A (en) * 1983-02-07 1985-01-29 Trutek Research, Inc. Inhalation therapy apparatus
JPS6029886A (ja) * 1983-07-29 1985-02-15 Dai Ichi Seiko Co Ltd 零復帰式カウンタ−
GB8323199D0 (en) 1983-08-30 1983-09-28 Dearing Lambert P R Container for medicines
ES277095Y (es) 1984-01-25 1985-02-16 Fernandez-Tresguerres Hernandez Jesus A. Suministrador-dosificador de productos inyectables
DE3405352A1 (de) 1984-02-15 1985-08-22 Paul Dr.med. 4300 Essen Behrendt Vorrichtung zum applizieren pastoeser stoffe, insbesondere pharmazeutischer oder kosmetischer praeparate
SE8401796D0 (sv) 1984-04-02 1984-04-02 Draco Ab Doseringsanordning
FI76929C (fi) 1984-09-25 1989-01-10 Etelae Haemeen Keuhkovammayhdi Inhalationsdoseringsanordning, som aer avsedd foer nogrann dosering av disponerande laekemedel som ges aot andningssjuka i undersoekningsskedet och/eller laekemedel som ges som spray under behandlingen.
DK481884D0 (da) * 1984-10-09 1984-10-09 Karl Holm Medicinsk mund- eller svaelgsprayapparat
NZ209900A (en) 1984-10-16 1989-08-29 Univ Auckland Automatic inhaler
GB2170780A (en) 1985-02-09 1986-08-13 Trumeter Company Limited Dispensing device having counting mechanism
US4805811A (en) * 1985-03-29 1989-02-21 Aktiebolaget Draco Dosage device
DE3511870C1 (de) 1985-04-01 1986-06-26 J. Hengstler Kg, 7209 Aldingen Impulszaehler als elektromechanisches Zaehlwerk mit Schwingspulenantrieb
DE3677886D1 (de) 1985-10-24 1991-04-11 Sandoz Ag Aerosolspender mit vollstaendiger verzoegerter ausgabe.
DE3545703C1 (de) 1985-12-21 1987-05-14 Hengstler Kg Null- oder Rueckstelleinrichtung fuer Rollenzaehlwerke
DE8602238U1 (de) 1986-01-29 1986-04-10 Josef Wischerath GmbH & Co KG, 5000 Köln Mundrohr mit einem Sprühkopf zum Abgeben eines zu inhalierenden Mediums aus einer Sprühdose
US4809692A (en) * 1986-01-31 1989-03-07 Trudell Medical Pediatric asthmatic medication inhaler
SE8601351D0 (sv) * 1986-03-24 1986-03-24 Nilsson Sven Erik Styrd administration av fysiologiskt aktiva emnen
US4705811A (en) * 1986-04-07 1987-11-10 The Dow Chemical Company Expandable polymeric composition and method
CA1258054A (fr) 1986-04-25 1989-08-01 Robert E. Newell Indicateur
GB8612886D0 (en) 1986-05-28 1986-07-02 Gocman B Pressurised inhaler alarm
GB2195544A (en) 1986-08-04 1988-04-13 Universal Precision Moulders L Inhaler
FR2606506B1 (fr) 1986-11-06 1992-12-31 Valois Dispositif de vaporisateur doseur muni d'un moyen de comptage des doses emises
GB2199308A (en) 1987-01-02 1988-07-06 John Burdon Timed drug package dispenser
DE3705962A1 (de) 1987-02-25 1988-09-08 Hengstler Gmbh Mechanisches rollenzaehlwerk
DK166948B1 (da) 1988-02-10 1993-08-09 Dcp Af 1988 As Doseringsenhed til dosering af et antal afmaalte maengder af en vaeske, saasom insulin, fra en glastubule
DE8805055U1 (de) * 1988-04-16 1988-06-09 Hengstler GmbH, 78554 Aldingen Betriebsstundenzähler
DE3827639A1 (de) * 1988-08-16 1990-02-22 Basf Ag Katalysator fuer die oxidation und ammonoxidation von (alpha),ss-ungesaettigten kohlenwasserstoffen
DE3828463A1 (de) * 1988-08-22 1990-03-01 Vdo Schindling Einrichtung zur verstellung eines rueckstellbaren zaehlwerks
IE62780B1 (en) * 1988-09-10 1995-02-22 Fisons Plc Inhalation devices with a reduced risk of blockage
US5148355A (en) * 1988-12-24 1992-09-15 Technology Applications Company Limited Method for making printed circuits
US5009338A (en) * 1989-02-03 1991-04-23 Senetics Corporation Indicator cap for a medicine bottle
US5718355A (en) 1989-02-03 1998-02-17 Senetics, Inc. Indicator device responsive to axial force for use with inhaler
US5261548A (en) * 1989-02-03 1993-11-16 Senetics, Inc. Indicator cap for use with threaded or bayonet lug container
US5242067A (en) * 1989-02-03 1993-09-07 Senetics, Inc. Adaptor for indicator device
AU623730B2 (en) * 1989-02-08 1992-05-21 Becton Dickinson & Company Syringe having graphic visualization features
SE466684B (sv) 1989-03-07 1992-03-23 Draco Ab Anordning vid en inhalator samt foerfarande foer att med anordningen registrera medicinering med inhalator
US4955371A (en) * 1989-05-08 1990-09-11 Transtech Scientific, Inc. Disposable inhalation activated, aerosol device for pulmonary medicine
GB8919131D0 (en) 1989-08-23 1989-10-04 Riker Laboratories Inc Inhaler
US5020527A (en) * 1990-02-20 1991-06-04 Texax-Glynn Corporation Inhaler device with counter/timer means
US5042467A (en) * 1990-03-28 1991-08-27 Trudell Medical Medication inhaler with fitting having a sonic signalling device
US5226896A (en) 1990-04-04 1993-07-13 Eli Lilly And Company Dose indicating injection pen
GB9015522D0 (en) 1990-07-13 1990-08-29 Braithwaite Philip W Inhaler
DE4027669A1 (de) * 1990-08-31 1992-03-05 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung fuer medien
JPH0450059U (fr) * 1990-09-05 1992-04-27
IT1243820B (it) 1990-10-09 1994-06-28 Elettro Plastica Spa Dispositivo contadosi per erogatore di dosi di prodotto fluido, particolarmente per uso farmaceutico
JP3532204B2 (ja) 1991-03-05 2004-05-31 アラダイム コーポレーション 流量計の圧力センサのドリフトオフセットを補正する方法および装置
AU650953B2 (en) 1991-03-21 1994-07-07 Novartis Ag Inhaler
ATE189124T1 (de) * 1991-07-02 2000-02-15 Inhale Inc Verfahren und vorrichtung zum abgeben von medikamenten in aerosolform
IT222834Z2 (it) 1991-07-23 1995-05-08 Sandoz Prodotti Farmaceutici S Dispositivo dosatore del tipo a pulsante con contatore di numero di corse
US5328486A (en) 1991-11-19 1994-07-12 American Cyanamid Company Syringe for dispensing multiple dosages
GB2263068B (en) 1991-12-19 1996-05-01 Minnesota Mining & Mfg Inhalation device
GB2262452B (en) 1991-12-19 1995-12-20 Minnesota Mining & Mfg Inhalation device
US5363842A (en) * 1991-12-20 1994-11-15 Circadian, Inc. Intelligent inhaler providing feedback to both patient and medical professional
US5300042A (en) * 1992-03-02 1994-04-05 Kossoff-Sukel, Inc. Medication dispensing apparatus
GB9205823D0 (en) 1992-03-18 1992-04-29 Heywood Roy V Medicine containers
GB9211436D0 (en) * 1992-05-29 1992-07-15 Norton Healthcare Ltd Dose indicating device
US5284133A (en) * 1992-07-23 1994-02-08 Armstrong Pharmaceuticals, Inc. Inhalation device with a dose-timer, an actuator mechanism, and patient compliance monitoring means
US5358117A (en) * 1992-08-25 1994-10-25 James Adams Medicine container cap with time indicator
US5279422A (en) * 1992-08-25 1994-01-18 Adams James E Medicine container cap with time indicator
JPH0626891U (ja) * 1992-09-09 1994-04-12 株式会社ラジカルスタッフ 吸入器のカウンター表示装置
US5259499A (en) * 1992-12-10 1993-11-09 St. Francis Research Institute System and apparatus for accurate drug inventory control
KR0163472B1 (ko) * 1992-12-18 1998-11-16 에릭 에스. 딕커 분말 약품용 흡입기
US6012450A (en) * 1993-01-29 2000-01-11 Aradigm Corporation Intrapulmonary delivery of hematopoietic drug
US5433343A (en) 1993-07-30 1995-07-18 Meshberg; Philip Delivery system for measured quantities of liquids, especially medications
US5505192A (en) 1993-11-12 1996-04-09 New-Med Corporation Dispenser monitoring system
DE4422710C1 (de) * 1994-06-29 1995-09-14 Boehringer Ingelheim Kg Inhalationsgerät mit einem Elektronikmodul zur Funktionsüberwachung
US5411173A (en) 1993-12-17 1995-05-02 Weinstein; Albert Counter attachment for product dispensers
US5564414A (en) * 1994-05-26 1996-10-15 Walker; William F. Pressurized and metered medication dose counter on removable sleeve
FR2721106B1 (fr) * 1994-06-10 1996-09-13 Step Compteur de doses pour inhalateurs.
US5482030A (en) * 1994-06-13 1996-01-09 Klein; David Aerosol and non-aerosol spray counter
US5464970A (en) * 1994-06-16 1995-11-07 Delco Electronics Corporation Multiple counter assembly
US5645534A (en) 1994-06-24 1997-07-08 Becton Dickinson And Company Time of last injection indicator for medication delivery pen
US5817822A (en) 1994-06-24 1998-10-06 Novartis Corporation Certain alpha-azacycloalkyl substituted arylsulfonamido acetohydroxamic acids
US5544647A (en) 1994-11-29 1996-08-13 Iep Group, Inc. Metered dose inhalator
US5622163A (en) 1994-11-29 1997-04-22 Iep Group, Inc. Counter for fluid dispensers
SE9404140D0 (sv) * 1994-11-29 1994-11-29 Astra Ab Dose indicating device
US5772074A (en) * 1995-03-31 1998-06-30 Waterbury Companies, Inc. Device and method for indicating the dispensing of a predetermined amount of a material
DE69637257T2 (de) * 1995-04-14 2008-06-12 Smithkline Beecham Corp. Verfahren zur Herstellung eines Dosierinhalators
US6029659A (en) * 1995-04-17 2000-02-29 Solar Shield Corporation Inhalation device with counter
US5809997A (en) * 1995-05-18 1998-09-22 Medtrac Technologies, Inc. Electronic medication chronolog device
US5625659A (en) * 1995-05-19 1997-04-29 Gojo Industries, Inc. Method and apparatus for electronically measuring dispenser usage
US6139669A (en) * 1995-06-07 2000-10-31 Super Sack Mfg. Corp. Anti-microbial shoe linings, sock liners and socks and process for manufacture of same
US5826571A (en) 1995-06-08 1998-10-27 Innovative Devices, Llc Device for use with metered dose inhalers (MDIS)
DE19549033C1 (de) * 1995-12-28 1997-05-28 Boehringer Ingelheim Int Mechanisches Zählwerk für ein Dosiergerät
US5676129A (en) * 1996-03-14 1997-10-14 Oneida Research Services, Inc. Dosage counter for metered dose inhaler (MDI) systems using a miniature pressure sensor
FR2750780B1 (fr) 1996-07-05 1998-10-30 Valois Compteur de doses
US5816228A (en) * 1997-02-19 1998-10-06 Avl Powertrain Engineering, Inc. Fuel injection system for clean low viscosity fuels
US5794612A (en) * 1997-04-02 1998-08-18 Aeromax Technologies, Inc. MDI device with ultrasound sensor to detect aerosol dispensing
US5871007A (en) * 1997-06-09 1999-02-16 Chase Marketing International L.L.C. Throat spray counting mechanism
TW533865U (en) 1997-06-10 2003-05-21 Glaxo Group Ltd Dispenser for dispensing medicament and actuation indicating device
US6327037B1 (en) * 1997-11-12 2001-12-04 Chien Chou Optical rotation angle polarimeter
US6142339A (en) 1998-01-16 2000-11-07 1263152 Ontario Inc. Aerosol dispensing device
EP1449557B1 (fr) * 1998-01-16 2016-09-07 Trudell Medical International Dispositif de distribution en forme de kit
US5924303A (en) * 1998-03-09 1999-07-20 California Innovations Inc. Insulated soft-sided portable case having externally accessible receptacle
US6082358A (en) * 1998-05-05 2000-07-04 1263152 Ontario Inc. Indicating device for aerosol container
US6729330B2 (en) * 1998-05-05 2004-05-04 Trudell Medical International Indicating device for aerosol container
US6336453B1 (en) * 1999-04-30 2002-01-08 Trudell Medical International Indicating device for aerosol container
US6260549B1 (en) * 1998-06-18 2001-07-17 Clavius Devices, Inc. Breath-activated metered-dose inhaler
US6223744B1 (en) * 1999-03-16 2001-05-01 Multi-Vet Ltd. Wearable aerosol delivery apparatus
US6202642B1 (en) * 1999-04-23 2001-03-20 Medtrac Technologies, Inc. Electronic monitoring medication apparatus and method
US6234166B1 (en) * 1999-06-30 2001-05-22 Acktar Ltd. Absorber-reflector for solar heating
WO2001016029A1 (fr) * 1999-08-31 2001-03-08 Kimberly-Clark Worldwide, Inc. Systeme de purification portatif
US6516799B1 (en) * 1999-09-08 2003-02-11 Sapphire Design, Inc. Inhalation counter device
FR2799858B1 (fr) * 1999-10-19 2002-01-18 Valois Sa Compteur de doses et distributeur de produit fluide incorporant un tel compteur
FR2817847B1 (fr) 2000-12-08 2003-03-28 Tebro Dispositif de distribution de produit fluide ou pulverulent
DE10063013B4 (de) * 2000-12-16 2011-06-30 Dr. Johannes Heidenhain GmbH, 83301 Winkelmesseinrichtung
PT1516283E (pt) * 2002-06-21 2009-05-11 Glaxo Group Ltd Indicador de accionamento para um dispositivo de distribuição

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5228586A (en) * 1990-08-31 1993-07-20 Ing. Erich Pfeiffer Gmbh & Co. Kg Media dispenser with removable use index
US5289946A (en) * 1990-08-31 1994-03-01 Ing. Erich Pfeiffer Gmbh & Co. Kg Dispenser for media
US5349945A (en) * 1990-11-26 1994-09-27 Minnesota Mining And Manufacturing Company Aerosol dispenser comprising an indicator assembly
WO1992017231A1 (fr) * 1991-03-28 1992-10-15 Innomed, Inc. Inhalateur microelectronique possedant un compteur et un minuteur

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TR199903066T2 (xx) 2000-07-21
NZ501379A (en) 2002-04-26
EA199901017A1 (ru) 2000-06-26
DE69826039D1 (de) 2004-10-07
PE99099A1 (es) 1999-10-22
DE69831739D1 (de) 2005-11-03
KR20010013630A (ko) 2001-02-26
CA2293488A1 (fr) 1998-12-17
PT986412E (pt) 2002-09-30
US20030209239A1 (en) 2003-11-13
TW533865U (en) 2003-05-21
CA2293488C (fr) 2005-12-06
US7107986B2 (en) 2006-09-19
HU228280B1 (en) 2013-02-28
NO996085L (no) 2000-02-09
ES2249834T3 (es) 2006-04-01
EP0986412A1 (fr) 2000-03-22
IS5282A (is) 1999-11-30
WO1998056445A1 (fr) 1998-12-17
ATE305320T1 (de) 2005-10-15
JP2000513632A (ja) 2000-10-17
CN1265601A (zh) 2000-09-06
MA24562A1 (fr) 1998-12-31
EP0988078A1 (fr) 2000-03-29
DE69804609D1 (de) 2002-05-08
US6431168B1 (en) 2002-08-13
JP2000513634A (ja) 2000-10-17
IN192609B (fr) 2004-05-08
HRP980304A2 (en) 1999-04-30
WO1998056446A1 (fr) 1998-12-17
JP3487866B2 (ja) 2004-01-19
US6601582B2 (en) 2003-08-05
EP0988078B1 (fr) 2005-09-28
ES2227031T3 (es) 2005-04-01
CO4830464A1 (es) 1999-08-30
AU8213898A (en) 1998-12-30
EP0988077B1 (fr) 2003-10-08
US6474331B1 (en) 2002-11-05
DE69831739T2 (de) 2006-04-27
HUP0003328A2 (hu) 2001-02-28
CA2293487A1 (fr) 1998-12-17
EP0988077A1 (fr) 2000-03-29
MY124574A (en) 2006-06-30
EP0986412B1 (fr) 2002-04-03
ATE251481T1 (de) 2003-10-15
EP1163922A2 (fr) 2001-12-19
ES2175737T3 (es) 2002-11-16
US20020195102A1 (en) 2002-12-26
HUP0003328A3 (en) 2001-04-28
BR9809554A (pt) 2000-06-20
PT988077E (pt) 2004-03-31
DK1163922T3 (da) 2004-11-29
PL337316A1 (en) 2000-08-14
IL133219A (en) 2004-12-15
CA2293487C (fr) 2005-12-13
ES2207841T3 (es) 2004-06-01
AU741693B2 (en) 2001-12-06
EG21520A (en) 2001-11-28
ATE215389T1 (de) 2002-04-15
PT1163922E (pt) 2004-12-31
NO331497B1 (no) 2012-01-16
KR100493837B1 (ko) 2005-06-08
US8245704B2 (en) 2012-08-21
NO996085D0 (no) 1999-12-09
IS2177B (is) 2006-12-15
AP1126A (en) 2002-12-05
US6360739B1 (en) 2002-03-26
WO1998056444A1 (fr) 1998-12-17
AR012939A1 (es) 2000-11-22
JP2000513633A (ja) 2000-10-17
AU8213798A (en) 1998-12-30
CN1150038C (zh) 2004-05-19
ID24128A (id) 2000-07-06
US20060289008A1 (en) 2006-12-28
DE69804609T2 (de) 2002-09-12
AP9901705A0 (en) 1999-12-31
ATE274952T1 (de) 2004-09-15
EP1163922B1 (fr) 2004-09-01
RS49632B (sr) 2007-08-03
DK0986412T3 (da) 2002-07-22
AU742913B2 (en) 2002-01-17
HK1023956A1 (en) 2000-09-29
JP3487865B2 (ja) 2004-01-19
HRP980304B1 (en) 2003-06-30
CA2293484C (fr) 2010-04-13
CA2293484A1 (fr) 1998-12-17
BR9809983A (pt) 2000-08-01
IL133219A0 (en) 2001-03-19
YU65799A (sh) 2001-05-28
DE69826039T2 (de) 2005-09-22
DE69818819D1 (de) 2003-11-13
EP1475116A3 (fr) 2010-11-17
DK0988077T3 (da) 2004-01-12
JP3487867B2 (ja) 2004-01-19
PL188988B1 (pl) 2005-05-31
AU8436498A (en) 1998-12-30
BR9809980A (pt) 2000-08-01
AU741218B2 (en) 2001-11-29
EP1475116A2 (fr) 2004-11-10
DE69818819T2 (de) 2004-08-12
EA001396B1 (ru) 2001-02-26

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