EP0800073B1 - Pretreatment apparatus - Google Patents

Pretreatment apparatus Download PDF

Info

Publication number
EP0800073B1
EP0800073B1 EP97302315A EP97302315A EP0800073B1 EP 0800073 B1 EP0800073 B1 EP 0800073B1 EP 97302315 A EP97302315 A EP 97302315A EP 97302315 A EP97302315 A EP 97302315A EP 0800073 B1 EP0800073 B1 EP 0800073B1
Authority
EP
European Patent Office
Prior art keywords
needle
tank
diluting
pretreatment
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP97302315A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP0800073A3 (en
EP0800073A2 (en
Inventor
Shingo Fukunaga
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tosoh Corp
Original Assignee
Tosoh Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tosoh Corp filed Critical Tosoh Corp
Publication of EP0800073A2 publication Critical patent/EP0800073A2/en
Publication of EP0800073A3 publication Critical patent/EP0800073A3/en
Application granted granted Critical
Publication of EP0800073B1 publication Critical patent/EP0800073B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38Diluting, dispersing or mixing samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/04Preparation or injection of sample to be analysed
    • G01N30/06Preparation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1004Cleaning sample transfer devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1079Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices with means for piercing stoppers or septums

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
EP97302315A 1996-04-04 1997-04-04 Pretreatment apparatus Expired - Lifetime EP0800073B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP08254196A JP3572792B2 (ja) 1996-04-04 1996-04-04 前処理装置
JP82541/96 1996-04-04
JP8254196 1996-04-04

Publications (3)

Publication Number Publication Date
EP0800073A2 EP0800073A2 (en) 1997-10-08
EP0800073A3 EP0800073A3 (en) 1998-04-22
EP0800073B1 true EP0800073B1 (en) 2004-09-29

Family

ID=13777374

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97302315A Expired - Lifetime EP0800073B1 (en) 1996-04-04 1997-04-04 Pretreatment apparatus

Country Status (4)

Country Link
US (2) US6066298A (ja)
EP (1) EP0800073B1 (ja)
JP (1) JP3572792B2 (ja)
DE (1) DE69730893T2 (ja)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6315952B1 (en) * 1998-10-05 2001-11-13 The University Of New Mexico Plug flow cytometry for high throughput screening and drug discovery
US6211956B1 (en) * 1998-10-15 2001-04-03 Particle Sizing Systems, Inc. Automatic dilution system for high-resolution particle size analysis
ATE246144T1 (de) * 1999-12-01 2003-08-15 Procter & Gamble Vorrichtung zu produktenlieferung
DE10001895A1 (de) * 2000-01-19 2001-07-26 Mettler Toledo Gmbh Analysenvorrichtung und Antriebsvorrichtung hierfür
EP1154270B1 (en) * 2000-05-09 2015-01-21 Tosoh Corporation Glycated hemoglobin analyzer
JP2002031626A (ja) * 2000-05-09 2002-01-31 Tosoh Corp 糖化ヘモグロビン分析計
JP2002001092A (ja) * 2000-06-22 2002-01-08 Shimadzu Corp 排液装置
US7439076B1 (en) * 2000-06-30 2008-10-21 Hitachi, Ltd. Liquid dispensing method and device
JP3665257B2 (ja) * 2000-07-11 2005-06-29 株式会社日立製作所 分注装置
US6852291B1 (en) * 2000-10-11 2005-02-08 Innovadyne Technologies, Inc. Hybrid valve apparatus and method for fluid handling
US7135146B2 (en) * 2000-10-11 2006-11-14 Innovadyne Technologies, Inc. Universal non-contact dispense peripheral apparatus and method for a primary liquid handling device
US6887429B1 (en) * 2001-01-26 2005-05-03 Global Fia Apparatus and method for automated medical diagnostic tests
FI20010190A (fi) * 2001-02-01 2002-08-02 Niilo Kaartinen Nestenäytteiden testauksessa käytettävä menetelmä, menetelmää soveltava testiyksikkö sekä testiyksiköitä sisältävä järjestelmä
ATE371179T1 (de) 2001-06-13 2007-09-15 Kenneth F Uffenheimer Automatisches flüssigkeitsbehandlungssystem und - verfahren
US6526812B2 (en) 2001-07-14 2003-03-04 Leap Technologies, Inc. Self-washing injection apparatus
ATE377763T1 (de) * 2002-01-25 2007-11-15 Innovadyne Technologies Inc Kontaktloses verfahren zur verteilung geringer flüssigkeitsvolumen
US7288228B2 (en) * 2002-02-12 2007-10-30 Gilson, Inc. Sample injection system
GB0218949D0 (en) * 2002-08-14 2002-09-25 Thermo Electron Corp Pumping and diluting a sample for analysis
GB0218946D0 (en) 2002-08-14 2002-09-25 Thermo Electron Corp Diluting a sample
JP3863087B2 (ja) * 2002-10-25 2006-12-27 シスメックス株式会社 試料分析装置およびその装置に使用されるピペット洗浄用希釈液
AU2003285719A1 (en) * 2003-01-13 2004-08-10 Pfizer Products Inc. System for rinsing a sample probe comprising a probe guide support
JP3826891B2 (ja) * 2003-03-05 2006-09-27 株式会社島津製作所 オートサンプラ
JP2004317420A (ja) * 2003-04-18 2004-11-11 Hitachi Software Eng Co Ltd キャピラリー利用測定装置
EP2413136B1 (en) * 2003-07-18 2013-07-03 Bio-Rad Laboratories, Inc. System and method for multi-analyte detection
US8012768B2 (en) 2003-07-18 2011-09-06 Bio-Rad Laboratories, Inc. System and method for multi-analyte detection
US7422905B2 (en) * 2004-02-27 2008-09-09 Medtronic, Inc. Blood coagulation test cartridge, system, and method
US7439069B2 (en) * 2004-02-27 2008-10-21 Nippoldt Douglas D Blood coagulation test cartridge, system, and method
US7399637B2 (en) * 2004-04-19 2008-07-15 Medtronic, Inc. Blood coagulation test cartridge, system, and method
US7621282B2 (en) * 2004-06-17 2009-11-24 Abbott Laboratories, Inc. Probe washing cups and methods
US7628954B2 (en) 2005-05-04 2009-12-08 Abbott Laboratories, Inc. Reagent and sample handling device for automatic testing system
JP4781075B2 (ja) * 2005-10-03 2011-09-28 シスメックス株式会社 検体分析装置
US20080034900A1 (en) * 2006-08-09 2008-02-14 Bollinger David S Apparatus and method to sample a material for later analysis
AU2008251904B2 (en) * 2007-05-11 2013-10-10 Bio-Rad Laboratories, Inc. Wash ring assembly and method of use
JP5162177B2 (ja) * 2007-07-31 2013-03-13 シスメックス株式会社 粒子分析装置及び粒子分析方法
CN101799400B (zh) * 2009-02-05 2011-09-28 浙江雷畴科技有限公司 一种在线液体光学检测分析装置
JP5111476B2 (ja) * 2009-10-26 2013-01-09 株式会社日立ハイテクノロジーズ 液体試料分析装置及び液体試料導入装置
US8733152B2 (en) * 2010-01-19 2014-05-27 Bio-Rad Laboratories, Inc. Automated analyzer with low-pressure in-line filtration
JP5843516B2 (ja) * 2010-08-25 2016-01-13 アークレイ株式会社 分析装置および分析方法
JP2012117945A (ja) * 2010-12-02 2012-06-21 Hitachi High-Technologies Corp 液体クロマトグラフ,液体クロマトグラフ用試料導入装置、および液体クロマトグラフ用試料導入装置の洗浄方法
JP5810630B2 (ja) * 2011-05-25 2015-11-11 東ソー株式会社 検体希釈装置
JP5806514B2 (ja) * 2011-05-31 2015-11-10 株式会社東芝 自動分析装置
JP5754298B2 (ja) * 2011-08-18 2015-07-29 東ソー株式会社 検体希釈装置を備えた分析装置
US9791465B2 (en) * 2012-02-22 2017-10-17 Hitachi High-Technologies Corporation Automatic analyzer
JP5799889B2 (ja) * 2012-05-15 2015-10-28 株式会社島津製作所 分取精製装置
CN103447268A (zh) * 2012-06-05 2013-12-18 北京普源精电科技有限公司 一种自动进样器及其洗针槽
KR101478458B1 (ko) * 2013-08-29 2014-12-31 김보곤 세정기능이 구비된 혈액점도측정장치
US10792655B2 (en) * 2014-12-10 2020-10-06 Wallac Oy Dispenser device and a method for rinsing the dispenser device
CN105842366B (zh) * 2015-01-15 2018-01-23 株式会社岛津制作所 样品注入装置
CN105457951A (zh) * 2015-12-30 2016-04-06 聚光科技(杭州)股份有限公司 清洗装置及方法
JP6774150B2 (ja) * 2016-02-19 2020-10-21 株式会社日立ハイテク 自動分析装置
WO2017199432A1 (ja) * 2016-05-20 2017-11-23 株式会社島津製作所 前処理装置及びその前処理装置を備えた分析システム
JP7052435B6 (ja) * 2018-03-09 2022-06-24 東洋紡株式会社 希釈・分注ノズル洗浄容器、分注・希釈システム、及び自動分析装置
EP3803377B1 (en) * 2018-05-29 2023-11-15 Waters Technologies Corporation Online sample manager
JP6828077B2 (ja) * 2019-03-28 2021-02-10 シスメックス株式会社 吸引管の洗浄方法および試料測定装置
CN114200070A (zh) * 2021-12-14 2022-03-18 嘉兴市唯真生物科技有限公司 一种液相色谱分析装置

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3192968A (en) * 1962-07-02 1965-07-06 Warner Lambert Pharmaceutical Apparatus for performing analytical procedures
FR2120300A5 (ja) * 1970-12-29 1972-08-18 Hoffmann La Roche
JPS5139382B2 (ja) * 1972-02-17 1976-10-27
JPS5523417A (en) * 1978-07-25 1980-02-19 Seishin Seiyaku Kk Automatic sample supply unit
JPS5782769A (en) * 1980-11-10 1982-05-24 Hitachi Ltd Automatic analyzing device
JPS5848836A (ja) * 1981-09-18 1983-03-22 Toa Medical Electronics Co Ltd 光学式自動分析測定装置
JPS60263850A (ja) * 1984-06-12 1985-12-27 Toshiba Corp 分析装置
JPS6182275U (ja) * 1984-11-02 1986-05-31
US4574850A (en) * 1985-01-17 1986-03-11 E. I. Du Pont De Nemours And Company Method of and apparatus for dispensing liquid
JPS61234336A (ja) * 1985-04-11 1986-10-18 Aloka Co Ltd 分注装置
US4730631A (en) * 1985-07-22 1988-03-15 Sequoia-Turner Corporation Probe wash station
US4946651A (en) * 1985-11-15 1990-08-07 Smithkline Diagnostics, Inc. Sample holder for a body fluid analyzer
US4820497A (en) * 1986-06-23 1989-04-11 E. I. Du Pont De Nemours And Company Movable cleaning assembly for an aspirating needle
FR2606885B1 (fr) * 1986-11-14 1989-08-04 Abx Sarl Dispositif de nettoyage d'une aiguille de prelevement d'un liquide
US4948563A (en) * 1987-05-08 1990-08-14 Abbott Laboratories Waste container insert for washing automated immunoassay apparatus probe
DE3885021T2 (de) * 1987-07-14 1994-05-19 Kyoto Daiichi Kagaku Kyoto Kk Automatische Messmethode für Glycohämoglobin.
JPH0197857A (ja) * 1987-07-14 1989-04-17 Kyoto Daiichi Kagaku:Kk グリコヘモグロビンの自動測定方法及び試料導入バルブ
FR2629207B1 (fr) * 1988-07-07 1991-05-31 Melet Francois Analyseur hematologique automatique a dispositif simplifie de prelevement et de distribution
JPH084617Y2 (ja) * 1989-10-20 1996-02-07 株式会社ニッテク サンプリング装置
US5132233A (en) * 1989-03-13 1992-07-21 Beckman Instruments, Inc. Sample injection cell
US4989623A (en) * 1989-12-01 1991-02-05 Akzo N.V. Apparatus and method for cleaning reagent delivery probes
JPH04105066A (ja) * 1990-08-24 1992-04-07 Olympus Optical Co Ltd プローブ洗浄容器
JP2568791B2 (ja) * 1992-07-15 1997-01-08 日機装 株式会社 試薬の希釈装置及び希釈方法
US5408891A (en) * 1992-12-17 1995-04-25 Beckman Instruments, Inc. Fluid probe washing apparatus and method
JPH06294802A (ja) * 1993-04-12 1994-10-21 Olympus Optical Co Ltd 自動分析装置
JPH0798306A (ja) * 1993-09-29 1995-04-11 Sekisui Chem Co Ltd 安定型糖化ヘモグロビン測定方法
US5558838A (en) * 1993-09-29 1996-09-24 Becton Dickinson And Company Sample preparation apparatus
JPH0798320A (ja) * 1993-09-29 1995-04-11 Shimadzu Corp 生化学自動分析装置
JP3311113B2 (ja) * 1993-10-19 2002-08-05 オリンパス光学工業株式会社 分析装置
JP3239199B2 (ja) * 1993-12-20 2001-12-17 シスメックス株式会社 ピペット洗浄装置
JPH08178824A (ja) * 1994-12-21 1996-07-12 Toa Medical Electronics Co Ltd 粒子測定装置
US5730938A (en) * 1995-08-09 1998-03-24 Bio-Chem Laboratory Systems, Inc. Chemistry analyzer
JP3239203B2 (ja) * 1995-12-19 2001-12-17 シスメックス株式会社 試料攪拌装置
JP3505906B2 (ja) * 1996-04-04 2004-03-15 東ソー株式会社 糖化ヘモグロビン分析装置

Also Published As

Publication number Publication date
DE69730893D1 (de) 2004-11-04
DE69730893T2 (de) 2005-02-03
JP3572792B2 (ja) 2004-10-06
US6066298A (en) 2000-05-23
EP0800073A3 (en) 1998-04-22
JPH09274048A (ja) 1997-10-21
EP0800073A2 (en) 1997-10-08
US6190614B1 (en) 2001-02-20

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