EG24142A - Crystalline monohydrate, process for the preparation thereof and the use thereof for preparing a pharmaceutical composition - Google Patents

Crystalline monohydrate, process for the preparation thereof and the use thereof for preparing a pharmaceutical composition

Info

Publication number
EG24142A
EG24142A EG20011058A EG20011058A EG24142A EG 24142 A EG24142 A EG 24142A EG 20011058 A EG20011058 A EG 20011058A EG 20011058 A EG20011058 A EG 20011058A EG 24142 A EG24142 A EG 24142A
Authority
EG
Egypt
Prior art keywords
preparing
preparation
pharmaceutical composition
crystalline monohydrate
monohydrate
Prior art date
Application number
EG20011058A
Other languages
English (en)
Inventor
Banholzer Rolf
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7659568&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EG24142(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Application granted granted Critical
Publication of EG24142A publication Critical patent/EG24142A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
EG20011058A 2000-10-12 2001-10-09 Crystalline monohydrate, process for the preparation thereof and the use thereof for preparing a pharmaceutical composition EG24142A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10050621 2000-10-12

Publications (1)

Publication Number Publication Date
EG24142A true EG24142A (en) 2008-08-06

Family

ID=7659568

Family Applications (1)

Application Number Title Priority Date Filing Date
EG20011058A EG24142A (en) 2000-10-12 2001-10-09 Crystalline monohydrate, process for the preparation thereof and the use thereof for preparing a pharmaceutical composition

Country Status (47)

Country Link
EP (2) EP1326862B1 (fr)
JP (1) JP3764422B2 (fr)
KR (1) KR100823860B1 (fr)
CN (2) CN100519558C (fr)
AP (1) AP1572A (fr)
AR (2) AR034389A1 (fr)
AT (1) ATE276253T1 (fr)
AU (2) AU1499602A (fr)
BG (1) BG66161B1 (fr)
BR (1) BR0114584A (fr)
CA (1) CA2425539C (fr)
CR (1) CR6938A (fr)
CZ (1) CZ301841B6 (fr)
DE (1) DE50103666D1 (fr)
DK (1) DK1326862T3 (fr)
DZ (1) DZ3478A1 (fr)
EA (1) EA004381B1 (fr)
EC (1) ECSP034540A (fr)
EE (1) EE04567B1 (fr)
EG (1) EG24142A (fr)
ES (1) ES2228965T3 (fr)
GE (1) GEP20063905B (fr)
HK (2) HK1060567A1 (fr)
HR (1) HRP20030276B1 (fr)
HU (1) HU226830B1 (fr)
IL (2) IL155335A0 (fr)
IS (1) IS2339B (fr)
MA (1) MA25842A1 (fr)
ME (2) ME00243B (fr)
MX (1) MXPA03003221A (fr)
MY (1) MY126931A (fr)
NO (1) NO328465B1 (fr)
NZ (1) NZ525733A (fr)
OA (1) OA12403A (fr)
PE (1) PE20020422A1 (fr)
PL (1) PL207870B1 (fr)
PT (1) PT1326862E (fr)
RS (1) RS50218B (fr)
SA (1) SA01220412B1 (fr)
SI (1) SI1326862T1 (fr)
SK (1) SK287009B6 (fr)
TR (1) TR200402579T4 (fr)
TW (1) TW589313B (fr)
UA (1) UA74215C2 (fr)
UY (2) UY26962A1 (fr)
WO (1) WO2002030928A1 (fr)
ZA (1) ZA200302500B (fr)

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US7311894B2 (en) 2002-03-28 2007-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg HFA suspension formulations containing an anticholinergic
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US7056916B2 (en) 2002-11-15 2006-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments for the treatment of chronic obstructive pulmonary disease
DE10317461A1 (de) 2003-04-16 2004-10-28 Boehringer Ingelheim Pharma Gmbh & Co. Kg Radioaktiv markierte Mikropartikel, Verfahren zu deren Herstellung und deren Verwendung
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ATE460414T1 (de) 2003-11-03 2010-03-15 Boehringer Ingelheim Int Verfahren zur herstellung von tiotropiumsalzen
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DE102004016179A1 (de) * 2004-03-30 2005-10-20 Boehringer Ingelheim Pharma Verbindungen zur Behandlung von proliferativen Prozessen
PT2422786E (pt) 2004-04-22 2014-11-12 Boehringer Ingelheim Int Novas combinações farmacêuticas para o tratamento de doenças respiratórias
US7220742B2 (en) 2004-05-14 2007-05-22 Boehringer Ingelheim International Gmbh Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
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DE102004048389A1 (de) 2004-10-01 2006-04-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Modifizierung von Oberflächen von Laktose als Hilfsstoff zur Verwendung für Pulverinhalativa
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RU2007144531A (ru) * 2005-05-02 2009-06-10 БЕРИНГЕР ИНГЕЛЬХАЙМ ИНТЕРНАЦИОНАЛЬ ГмбХ (DE) Новые кристаллические формы тиотропийбромида
NZ583872A (en) * 2005-06-15 2011-10-28 Boehringer Ingelheim Int Process for preparing tiotropium salts, tiotropium salts as such and pharmaceutical compositions thereof
DE102005030733A1 (de) 2005-07-01 2007-01-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff
BRPI0614394A2 (pt) * 2005-08-06 2011-03-29 Boehringer Ingelheim Int uso de sais de tiotrópio
CA2619402C (fr) 2005-08-15 2015-02-03 Boehringer Ingelheim International Gmbh Procede de production de betamimetiques
US20070086957A1 (en) 2005-10-10 2007-04-19 Thierry Bouyssou Combination of medicaments for the treatment of respiratory diseases
US7423146B2 (en) 2005-11-09 2008-09-09 Boehringer Ingelheim International Gmbh Process for the manufacturing of pharmaceutically active 3,1-benzoxazine-2-ones
DE102005059602A1 (de) * 2005-12-14 2007-06-21 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Mikronisierung
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EP1847543A1 (fr) 2006-04-19 2007-10-24 Boehringer Ingelheim Pharma GmbH & Co. KG Dihydrothienopyrimidines pour le traitement de maladies inflammatoires
BRPI0608387A2 (pt) 2006-04-19 2009-12-29 Boehringer Ingelheim Int compostos para o tratamento de doenças inflamatórias
US20080051582A1 (en) 2006-07-10 2008-02-28 Sicor Inc. Process for the preparation of tiotropium bromide
JP2010500318A (ja) 2006-08-07 2010-01-07 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 呼吸器疾患の治療用医薬組成物
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EP1923393A1 (fr) * 2006-11-17 2008-05-21 Boehringer Ingelheim Pharma GmbH & Co. KG Forme cristalline de tiotropium bromide avec urée
EP1925295A1 (fr) * 2006-11-22 2008-05-28 Boehringer Ingelheim Pharma GmbH & Co. KG Formule de poudre stable contenant un nouveau anticholinergique
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CN101827852B (zh) 2007-10-19 2014-07-30 贝林格尔.英格海姆国际有限公司 取代的哌啶子基-二氢噻吩并嘧啶
EP2093219A1 (fr) 2008-02-22 2009-08-26 Boehringer Ingelheim International Gmbh Forme de sel à énantiomère pur et cristalline d'un bêtamimétique et son utilisation comme médicament
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PL2379525T3 (pl) 2008-12-19 2016-01-29 Centrexion Therapeutics Corp Cykliczne pirymidyno-4-karboksamidy jako antagoniści receptora CCR2 do leczenia stanów zapalnych, astmy oraz COPD
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WO2010101538A2 (fr) 2009-03-06 2010-09-10 Bilgic Mahmut Nouvelles formes de cristaux
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JP5822831B2 (ja) 2009-08-07 2015-11-24 ジェネリクス・［ユーケー］・リミテッド チオトロピウム臭化物の無水物
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EP2569298B1 (fr) 2010-05-12 2015-11-25 Boehringer Ingelheim International GmbH Nouveaux antagonistes du récepteur ccr2, son procédé de production et utilisation associée en tant que médicaments
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JP5786258B2 (ja) 2011-07-15 2015-09-30 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規かつ選択的なｃｃｒ２拮抗薬
CA2843022C (fr) 2011-07-26 2019-09-24 Boehringer Ingelheim International Gmbh Quinoleines substituees et leur utilisation comme medicaments
US20130059866A1 (en) 2011-08-24 2013-03-07 Boehringer Ingelheim International Gmbh Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma
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RU2567539C1 (ru) * 2015-02-04 2015-11-10 Индивидуальный предприниматель Михайлов Олег Ростиславович КРИСТАЛЛИЧЕСКАЯ γ-МОДИФИКАЦИЯ (1α,2β,4β,5α,7β-7)-[(ГИДРОКСИДИ-2-ТИЕНИЛАЦЕТИЛ)ОКСИ]-9,9-ДИМЕТИЛ-3-ОКСА-9-АЗОНИАТРИЦИКЛО[3.3.1.02,4]НОНАН БРОМИДА МОНОГИДРАТА, СПОСОБ ЕЁ ПОЛУЧЕНИЯ И ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ НА ЕЁ ОСНОВЕ
WO2017138896A1 (fr) 2016-02-11 2017-08-17 Sima Patent Ve Lisanslama Hizmetleri Ltd. Şti Forme cristalline d'anhydrate de bromure de tiotropium
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DE19834506A1 (de) * 1998-07-31 2000-02-03 Hexal Ag Transmucosales therapeutisches System zur Anwendung von Sildenafil
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Also Published As

Publication number Publication date
SI1326862T1 (en) 2005-02-28
KR20030042008A (ko) 2003-05-27
CZ301841B6 (cs) 2010-07-07
IS2339B (is) 2008-02-15
ME00243B (me) 2011-05-10
HRP20030276B1 (en) 2006-02-28
SK4362003A3 (en) 2003-08-05
UY34901A (es) 2015-02-27
AU1499602A (en) 2002-04-22
HK1060567A1 (en) 2004-08-13
PT1326862E (pt) 2004-11-30
YU27303A (sh) 2006-05-25
DZ3478A1 (fr) 2002-04-18
SK287009B6 (sk) 2009-09-07
HK1086557A1 (en) 2006-09-22
CN1221549C (zh) 2005-10-05
EE200300171A (et) 2003-06-16
SA01220412B1 (ar) 2006-11-05
WO2002030928A1 (fr) 2002-04-18
TR200402579T4 (tr) 2004-12-21
BG66161B1 (bg) 2011-09-30
ZA200302500B (en) 2004-04-22
PL207870B1 (pl) 2011-02-28
EE04567B1 (et) 2005-12-15
GEP20063905B (en) 2006-08-25
AP1572A (en) 2006-02-13
NO328465B1 (no) 2010-02-22
MEP40008A (en) 2011-02-10
HU226830B1 (en) 2009-11-30
RS50218B (sr) 2009-07-15
IS6772A (is) 2003-04-09
EP1326862A1 (fr) 2003-07-16
PL366041A1 (en) 2005-01-24
HUP0301022A3 (en) 2005-12-28
JP2004526668A (ja) 2004-09-02
CN1733761A (zh) 2006-02-15
ECSP034540A (es) 2003-07-25
NO20031694L (no) 2003-04-11
MY126931A (en) 2006-10-31
CN1469877A (zh) 2004-01-21
CA2425539C (fr) 2007-04-03
AR068527A2 (es) 2009-11-18
AU2002214996B2 (en) 2007-03-15
EP1326862B1 (fr) 2004-09-15
UA74215C2 (uk) 2005-11-15
HUP0301022A2 (hu) 2003-10-28
ES2228965T3 (es) 2005-04-16
DE50103666D1 (de) 2004-10-21
OA12403A (en) 2006-04-18
CA2425539A1 (fr) 2003-04-11
TW589313B (en) 2004-06-01
IL155335A0 (en) 2003-11-23
NZ525733A (en) 2005-01-28
EP1468998A1 (fr) 2004-10-20
AR034389A1 (es) 2004-02-25
IL155335A (en) 2009-02-11
DK1326862T3 (da) 2004-11-22
MA25842A1 (fr) 2003-07-01
BG107687A (bg) 2003-09-30
EA004381B1 (ru) 2004-04-29
NO20031694D0 (no) 2003-04-11
AP2003002775A0 (en) 2003-03-31
HRP20030276A2 (en) 2005-02-28
MXPA03003221A (es) 2004-12-03
ATE276253T1 (de) 2004-10-15
KR100823860B1 (ko) 2008-04-21
PE20020422A1 (es) 2002-06-28
CN100519558C (zh) 2009-07-29
CR6938A (es) 2004-10-28
JP3764422B2 (ja) 2006-04-05
UY26962A1 (es) 2002-06-20
BR0114584A (pt) 2003-08-26
EA200300457A1 (ru) 2003-10-30

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