AU2001241056A1 - Spiro compounds, process for preparing the same and use thereof as drugs - Google Patents

Spiro compounds, process for preparing the same and use thereof as drugs

Info

Publication number
AU2001241056A1
AU2001241056A1 AU2001241056A AU4105601A AU2001241056A1 AU 2001241056 A1 AU2001241056 A1 AU 2001241056A1 AU 2001241056 A AU2001241056 A AU 2001241056A AU 4105601 A AU4105601 A AU 4105601A AU 2001241056 A1 AU2001241056 A1 AU 2001241056A1
Authority
AU
Australia
Prior art keywords
drugs
preparing
same
spiro compounds
spiro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001241056A
Inventor
Masakazu Fujio
Kenji Hashimoto
Jiro Katayama
Atsushi Numata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Pharma Corp
Original Assignee
Welfide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Welfide Corp filed Critical Welfide Corp
Publication of AU2001241056A1 publication Critical patent/AU2001241056A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/20Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/20Spiro-condensed systems
AU2001241056A 2000-03-09 2001-03-07 Spiro compounds, process for preparing the same and use thereof as drugs Abandoned AU2001241056A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000065545 2000-03-09
JP2000-65545 2000-03-09
PCT/JP2001/001793 WO2001066546A1 (en) 2000-03-09 2001-03-07 Spiro compounds, process for preparing the same and use thereof as drugs

Publications (1)

Publication Number Publication Date
AU2001241056A1 true AU2001241056A1 (en) 2001-09-17

Family

ID=18585048

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001241056A Abandoned AU2001241056A1 (en) 2000-03-09 2001-03-07 Spiro compounds, process for preparing the same and use thereof as drugs

Country Status (2)

Country Link
AU (1) AU2001241056A1 (en)
WO (1) WO2001066546A1 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002339810A1 (en) * 2001-10-16 2003-04-28 Astrazeneca Ab Azabicyclic compounds for the treatment of fibromyalgia syndrome
DE10164139A1 (en) 2001-12-27 2003-07-10 Bayer Ag 2-heteroaryl carboxamides
BR0312414A (en) * 2002-07-05 2005-05-10 Targacept Inc N-aryl diazaespirocyclic compounds and methods for their preparation and use
GB0220581D0 (en) 2002-09-04 2002-10-09 Novartis Ag Organic Compound
AU2004255920B2 (en) 2003-07-08 2008-05-15 Astrazeneca Ab Spiro [1-azabicyclo [2.2.2] octan-3,5'-oxazolidin]-2'-one derivatives with affinity to the alpha7 nicotinic acetylcholine receptor
PE20060437A1 (en) 2004-06-18 2006-06-08 Novartis Ag AZA-BICYCLONONE COMPOUNDS AS CHOLINERGIC LINKS OF nAChR
GB0415746D0 (en) 2004-07-14 2004-08-18 Novartis Ag Organic compounds
US8076349B2 (en) 2004-12-09 2011-12-13 Virochem Pharma Inc. Spirotropane compounds and methods for the modulation of chemokine receptor activity
BRPI0518859A2 (en) 2004-12-09 2008-12-09 Virochem Pharma Inc spirotropan compounds and methods for modulating chemokine receptor activity
JP2008524208A (en) * 2004-12-15 2008-07-10 アストラゼネカ・アクチエボラーグ Nicotinic acetylcholine receptor ligand
GB0521508D0 (en) 2005-10-21 2005-11-30 Novartis Ag Organic compounds
GB0525672D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
GB0525673D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
ITMI20061279A1 (en) * 2006-06-30 2008-01-01 Consiglio Nazionale Ricerche SELECTIVE NICOTINIC AGONISTS FOR THE ALFA7 RECEPTOR SUBTIPLE, PROCEDURE FOR THEIR PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS
CA2989633A1 (en) 2010-05-17 2011-11-24 Forum Pharmaceuticals Inc. A crystalline form of (r)-7-chloro-n-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide hydrochloride monohydrate
AU2013259871A1 (en) 2012-05-08 2014-11-20 Forum Pharmaceuticals Inc. Methods of maintaining, treating or improving cognitive function
WO2016100184A1 (en) 2014-12-16 2016-06-23 Forum Pharmaceuticals, Inc. Geminal substituted quinuclidine amide compounds as agonists of alpha-7 nicotinic acetylcholine receptors
KR20180044256A (en) 2015-06-10 2018-05-02 엑소반트 사이언시즈 게엠베하 Aminobenzoisooxazole compounds as agonists of the A7-nicotinic acetylcholine receptor
US10428062B2 (en) 2015-08-12 2019-10-01 Axovant Sciences Gmbh Geminal substituted aminobenzisoxazole compounds as agonists of α7-nicotinic acetylcholine receptors
AU2016340798A1 (en) * 2015-10-20 2018-04-26 Axovant Sciences Gmbh Aminoisoxazoline compounds as agonists of alpha7-nicotinic acetylcholine receptors
US10343991B2 (en) 2016-11-02 2019-07-09 Council Of Scientific & Industrial Research C5, C6 substituted and/or fused oxindoles as anti-cancer agents and process for preparation thereof
WO2022175402A1 (en) * 2021-02-18 2022-08-25 Aprea Therapeutics Ab Quinuclidine-3-one derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5534520A (en) * 1990-04-10 1996-07-09 Fisher; Abraham Spiro compounds containing five-membered rings
CZ289512B6 (en) * 1994-08-24 2002-02-13 Astra Aktiebolag Spiro-azabicyclic compounds useful in therapy

Also Published As

Publication number Publication date
WO2001066546A1 (en) 2001-09-13

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